N7-glycidamide-guanine DNA adduct formation by orally ingested acrylamide in rats: A dose-response study encompassing human diet-related exposure levels

Chemical Research in Toxicology

Volumn 25, Issue 2, 2012, Pages 381-390

  Watzek, Nico ^a   Bohm, Nadine ^a   Feld, Julia ^a   Scherbl, Denise ^a   Berger, Franz ^a   Merz, Karl Heinz ^a   Lampen, Alfonso ^b   Reemtsma, Thorsten ^b   Tannenbaum, Steven R ^c   Skipper, Paul L ^c   Baum, Matthias ^a   Richling, Elke ^a   Eisenbrand, Gerhard ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

^b FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ACRYLAMIDE; CARCINOGEN; GLYCIDAMIDE; GUANINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGEN DNA INTERACTION; CONTROLLED STUDY; DIET; DNA ADDUCT; DOSE RESPONSE; ELECTROPHILICITY; FEMALE; GENOTOXICITY; INGESTION; NONHUMAN; RAT; RISK ASSESSMENT; URINE;

ACRYLAMIDE; ANIMALS; CARCINOGENS; DIET; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOXY COMPOUNDS; FEMALE; GUANINE; HUMANS; KIDNEY; LIVER; LUNG; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84859773835     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx200446z     Document Type: Article

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