A comparison of genotoxicity between three common heterocyclic amines and acrylamide

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 580, Issue 1-2, 2005, Pages 103-110

  Durling, Louise J K ^a   Abramsson Zetterberg, Lilianne ^a  

^a NATIONAL FOOD ADMINISTRATION   (Sweden)

Author keywords

Acrylamide; Dose response; Erythrocytes; Heterocyclic amines; Micronucleus

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; ACRYLAMIDE; HETEROCYCLIC AMINE;

ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; DNA CONTENT; ERYTHROCYTE; FLOW CYTOMETRY; GENOTOXICITY; MALE; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACRYLAMIDE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; HETEROCYCLIC COMPOUNDS; IMIDAZOLES; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MICE, INBRED BALB C; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MUTAGENS; QUINOLINES; QUINOXALINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 12744268085     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2004.09.009     Document Type: Article

References (34)

1. E. Tareke, P. Rydberg, P. Karlsson, and M. Törnqvist Analysis of acrylamide, a carcinogen formed in heated foodstuffs J. Agric. Food Chem. 50 2002 4998 5006
2. N.J. Gooderham, S. Murray, A.M. Lynch, R.J. Edwards, M. Yadollahi-Farsani, C. Bratt, K.J. Rich, K. Zhao, B.P. Murray, S. Bhadresa, S.J. Crosbie, A.R. Boobis, and D.S. Davies Heterocyclic amines: evaluation of their role in the diet associated human cancer Br. J. Clin. Pharmacol. 42 1996 91 98
3. T. Sugimura Nutrition and dietary carcinogens Carcinogenesis 21 2000 387 395
4. R.J. Turesky Heterocyclic aromatic amine metabolism, DNA adduct formation, mutagenesis, and carcinogenesis Drug. Metab. Rev. 34 2002 625 650
5. K. Svensson, L. Abramsson, W. Becker, A. Glynn, K.-E. Hellenäs, Y. Lind, and J. Rosén Dietary intake of acrylamide in Sweden Food Chem. Toxicol. 41 2003 1581 1586
6. K. Skog Cooking procedures and food mutagens: a literature review Food Chem. Toxicol. 31 1993 655 675
7. M. Friedman Chemistry, biochemistry, and safety of acrylamide. A review J. Agric. Food Chem. 51 2003 4504 4526
8. E. Dybing, and T. Sanner Risk assessment of acrylamide in foods Toxicol. Sci. 75 2003 7 15
9. K. Augustsson, K. Skog, M. Jägerstad, and G. Steineck Assessment of the human exposure to heterocyclic amines Carcinogenesis 18 1997 1931 1935
10. B. Zimmerli, P. Rhyn, O. Zoller, and J. Schlatter Occurrence of heterocyclic aromatic amines in the Swiss diet: analytical method, exposure estimation and risk assessment Food Addit. Contam. 18 2001 533 551
11. G. Eisenbrand, and W. Tang Food-borne heterocyclic amines: chemistry, formation, occurrence and biological activities. A literature review Toxicology 84 1993 1 82
12. IARC Monographs on the evaluation of carcinogenic risks to human: some industrial chemicals no. 60, International Agency for Research on Cancer, Lyon, 1994, pp. 389-433.
13. IARC Monographs on the evaluation of carcinogenic risks to human: some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins no. 56, International Agency for Research on Cancer, Lyon, 1993, pp. 165-229.
14. S. Knasmüller, C.E. Schwab, S.J. Land, C.Y. Wang, R. Sanyal, M. Kundi, W. Parzefall, and F. Darroudi Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells Mutagenesis 14 1999 533 539
15. W. Pfau, F.L. Martin, K.J. Cole, S. Venitt, D.H. Phillips, P.L. Grover, and H. Marquardt Heterocyclic aromatic amines induce DNA strand breaks and cell transformation Carcinogenesis 20 1999 545 551
16. N. Loprieno, G. Boncristiani, and G. Loprieno An experimental approach to identifying the genotoxic risk from cooked meat mutagens Food Chem. Toxicol. 29 1991 337 386
17. J.D. Tucker, A.V. Carrano, N.A. Allen, M.L. Christensen, M.G. Knize, C.L. Strout, and J.S. Felton In vivo cytogenetic effects of cooked food mutagens Mutat. Res. 224 1989 105 113
18. J.M. Parry, E.M. Parry, R. Bourner, A. Doherty, S. Ellard, J. O'Donovan, B. Hoebee, J.M. Stoppelaar, G.R. Mohn, A. Onfelt, A. Renglin, N. Schultz, C. Soderpalm-Berndes, K.G. Jensen, M. Kirsch-Volders, A. Elhajouji, P. Van Hummelen, F. Degrassi, A. Antoccia, D. Cimini, M. Izzo, C. Tanzarella, I.D. Adler, U. Kliesch, G. Schriever-Schwemmer, P. Gasser, R. Crebelli, A. Carere, C. Andreoli, R. Benigni, P. Leopardi, F. Marcon, Z. Zinjo, A.T. Natarajan, J.J.W.A. Boei, A. Kappas, G. Voutsinas, F.E. Zarani, A. Patrinelli, F. Pachierotti, C. Tiveron, and P. Hess The detection and evaluation of aneugenic chemicals Mutat. Res. 353 1996 11 46
19. J. Grawé, L. Abramsson-Zetterberg, L. Eriksson, and G. Zetterberg The relationship between DNA content and centromere content in micronucleated mouse bone marrow erythrocytes analysed by flow cytometry and fluorescent in situ hybridization Mutagenesis 9 1994 31 38
20. L. Abramsson-Zetterberg The dose response relationship at very low doses of acrylamide is linear in the flow cytometer-based mouse micronucleus assay Mutat. Res. 535 2002 215 222
21. J. Cao, W. Beisker, M. Nüsse, and I.D. Adler Flow cytometric detection of micronuclei induced by chemicals in poly- and normochromatic erythrocytes of mouse peripheral blood Mutagenesis 8 1993 533 541
22. J.T. Mac Gregor, C.C. Wehr, and D.H. Gould Clastogen-induced micronuclei in peripheral blood erythrocytes: the basis of an improved micronucleus test Environ. Mutagen 2 1980 509 514
23. R.J. Cole, N. Taylor, J. Cole, and C.F. Arlett Short-term tests for transplacentally active carcinogens. I. Micronucleus formation in fetal and maternal mouse erythroblasts Mutat. Res. 80 1981 141 157
24. L. Abramsson-Zetterberg, G. Zetterberg, and J. Grawé The time course of micronucleated polychromatic erythrocytes in mouse bone marrow and peripheral blood Mutat. Res. 350 1996 349 358
25. L. Abramsson-Zetterberg, J. Grawé, and G. Zetterberg Flow cytometric analysis of micronucleus induction in mice by internal exposure to 137 Cs at very low dose rates Int. J. Radiat. Biol. 67 1995 29 36
26. J. Grawé, G. Zetterberg, and H. Amnéus Flow-cytometric enumeration of micronucleated polychromatic erythrocytes in mouse peripheral blood Cytometry 13 1992 750 758
27. H. Hayashi, H. Norppa, and T. Sofuni Jr. Ishidate, Flow cytometric micronucleus test with mouse peripheral erythrocytes Mutagenesis 7 1992 257 264
28. J. Grawé, L. Abramsson-Zetterberg, and G. Zetterberg Low dose effects of chemicals as assessed by the flow cytometric in vivo micronucleus assay Mutat. Res. 405 1998 199 208
29. R.S. King, F.F. Kadlubar, and R.J. Turesky In vivo metabolism of heterocyclic amines M. Nagao T. Sugimura Food Borne Carcinogens: Heterocyclic Amines 2000 Wiley West Sussex 90 111
30. K.L. Dearfield, C.O. Abernathy, M.S. Ottley, J.H. Brantner, and P.F. Hayes Acrylamide: its metabolism, developmental and reproductive effects, genotoxicity, and carcinogenicity Mutat. Res. 195 1988 45 77
31. B. Paulsson, J. Grawé, and M. Törnqvist Hemoglobin adducts and micronucleus frequencies in mouse and rat after acrylamide or N-methylolacrylamide treatment Mutat. Res. 516 2002 101 111
32. B. Paulsson, N. Kotova, J. Grawé, A. Henderson, F. Granath, B. Golding, and M. Törnqvist Induction of micronuclei in mouse and rat by glycidamide, genotoxic metabolite of acrylamide Mutat. Res. 535 2003 15 24
33. J.A. Holme, H. Wallin, G. Brunborg, E.J. Soderlund, J.K. Hongslo, and J. Alexander Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP): formation of 2-hydroxamino-PhIP, a directly acting genotoxic metabolite Carcinogenesis 10 1989 1389 1396
34. M.A. Cheeseman, E.J. Machuga, and A.B. Bailey A tiered approach to threshold of regulation Food Chem. Toxicol. 37 1999 387 412