Sulphur dioxide: A potent glutathione depleting agent

Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology

Volumn 114, Issue 2, 1996, Pages 89-98

  Langley Evans, Simon C ^a   Phillips, Gary J ^a   Jackson, Alan A ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

bronchoalveolar lavage; glutathione; lung; rat; suphur dioxide

Indexed keywords

GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; SULFUR DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HEART; INHALATION; KIDNEY; LIVER; LUNG LAVAGE; LUNG TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030176048     PISSN: 07428413     EISSN: None     Source Type: Journal    
DOI: 10.1016/0742-8413(96)00012-6     Document Type: Article

References (28)

1. 1. Anderson, M.; Meister, A. Transport and direct utilization of γ-glutamylcysteine for glutathione synthesis. Proc. Natl. Acad. Sci. USA 80:707-711;1983.
2. 2. Atzori, L.; Bannenberg, G.; Corriga, A.M.; Moldeus, P.; Ryrfeldt, A. Sulfur dioxide-induced bronchoconstriction in the isolated and perfused guinea pig lung. Respiration 59:16-21; 1992.
3. 3. Basbaum, C.; Gallup, M.; Gum, J.; Kim, Y.; Jany, B. Modification of mucin gene expression in the airways of rats exposed to sulfur dioxide. Biorheology 27:485-489;1990.
4. 4. Cantin, A.M.; North, S.L.; Hubbard, R.C.; Crystal, R.C. Normal alveolar epithelial lining fluid contains high levels of glutathione. J. Appl. Physiol. 63:152-157;1987.
5. 5. Deneke, S.M.; Fanburg, B.L. Regulation of cellular glutathione. Am. J. Physiol. 257:L163-L173;1989.
6. 6. Freeman, B.A.; Crapo, J.D. Biology of disease: free radicals and tissue injury. Lab. Invest. 47:412-426;1982.
7. 7. Gan, Z.-R.; Wells, W.W. Purification and properties of thioltransferase. J. Biol. Chem. 261:996-1001;1986.
8. 8. Gong, H. Health effects of air pollution. Clin. Chest Med. 13:201-214;1992.
9. 9. Griffith, O.W. Determination of glutathione and glutathione disulphide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106:207-212;1980.
10. 10. Hunter, E.A.L.; Grimble, R.F. Cysteine and methionine supplementation modulate the effect of tumor necrosis factor on protein synthesis, glutathione and zinc concentrations of liver and lung in rats fed a low protein diet. J. Nutr. 124:2319-2328;1994.
11. 11. Jenkinson, S.G.; Lawrence, R.A.; Tucker, W.Y. Glutathione peroxidase, superoxide dismutase and glutathione S-transferase activities in human lung. Am. Rev. Respir. Dis. 130: 302-304;1984.
12. 12. Jenkinson, S.G.; Black, R.D.; Lawrence, R.A. Glutathione concentration in rat lung bronchoalveolar lavage fluid: effects of hyperoxia. J. Lab. Clin. Med. 112:345-351;1988.
13. 13. Jones, S.M.; Brooks, B.A.; Langley, S.C.; Idle, J.R.; Hirom, P.C. Glutathione transferase activities of cultured human lymphocytes. Carcinogenesis 9:395-398;1988.
14. 14. Kagedal, B.; Kallberg, M.; Sorbo, B. A possible involvement of glutathione in the detoxification of sulfite. Biochem. Biophys. Res. Commun. 136:1036-1041;1986.
15. 15. Kelly, F.J.; Town, G.I.; Phillips, G.J.; Holgate, S.T.; Roche, W.R.; Postle, A.D. The preterm guinea pig: a model for the study of neonatal lung disease. Clin. Sci. 81:439-446;1991.
16. 16. Langley, S.C.; Kelly, F.J. Differing response of the glutathione system to fasting in neonatal and adult guinea pigs. Biochem. Pharmacol. 44:1489-1494;1992.
17. 17. Langley, S.C.; Kelly, F.J. N-Acetylcysteine ameliorates hyperoxic lung injury in the preterm guinea pig. Biochem. Pharmacol. 45:841-846;1993.
18. 18. Langley, S.C.; Seakins, M.; Grimble, R.F.; Jackson, A.A. The acute phase response of adult rats is altered by in utero exposure to maternal low protein diets. J. Nutr. 124:1588-1596; 1994.
19. 19. Mannervik, B.; Persson, G.; Eriksson, S. Enzymic conversion of the reversible sulfitolysis of glutathione disulfide and the biological reduction of thiosulfate esters. Arch. Biochem. Biophys. 163:282-289;1974.
20. 2 and NOx on benzo(a)pyrene activating enzymes of the rat liver. Exp. Pathol 39:207-212;1990.
21. 21. Sandstrom, T.; Stjernberg, N.; Andersson, M.-C.; Kolmodin-Hedman, B.; Lundgren, R.; Rosenhall, L.; Angstrom, T. Cell response in bronchoalveolar lavage fluid after exposure to sulfur dioxide: a time response study. Am. Rev. Respir. Dis. 140: 1828-1831;1989a.
22. 22. Sandstrom, T.; Stjernberg, N.; Andersson, M.-C.; Kolmodin-Hedman, B.; Lundgren, R.; Angstrom, T. Is the short term limit for sulphur dioxide exposure safe? Effects of a controlled chamber exposure investigated with bronchoalveolar lavage. Br. J. Ind. Med. 46:200-203;1989b.
23. 23. Smith, P.K.; Krohn, R.I.; Hermanson, G.T.; Mallia, A.K.; Gartre, F.H.; Provenzano, M.D.; Fujimoto, E.K.; Goeke, N.M.; Olson, B.J.; Klenk, D.C. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150:76-85;1985.
24. 24. Stjernberg, N.; Eklund, A.; Nystrom, L.; Rosenhall, L.; Emmelin, A.; Stromqvist, L.-H. Prevalence of bronchial asthma and chronic bronchitis in a community in Northern Sweden: relations to environmental and occupational exposure to sulphur dioxide. Eur. J. Respir. Dis. 67:41-49;1985.
25. 25. Stratmann, U.; Lehman, R.R.; Steinbech, T.; Wessling, G. Effect of sulfur dioxide inhalation on the respiratory tract of the rat. Zbl. Hyg. 192:324-335;1991.
26. 26. Tewari, A.; Shukla, N.P. Air pollution-adverse effects of sulfur dioxide. Rev. Environ. Health 9:39-45;1991.
27. 27. Tietze, F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione. Anal. Biochem. 27:502-522;1969.
28. 28. Tseng, R.Y.M.; Li, C.Y.K. Low level sulfur dioxide pollution and childhood asthma. Ann. Allergy 65:379-383;1990.