DNA strand breaking capacity of acrylamide and glycidamide in mammalian cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 580, Issue 1-2, 2005, Pages 71-80

  Puppel, Nicole ^a   Tjaden, Zeina ^a   Fueller, Florian ^a   Marko, Doris ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

Caco 2; Comet assay; Cytotoxicity; Glutathione; Rat hepatocytes; Strand breaks; V79

Indexed keywords

ACRYLAMIDE; AMIDE; BUTHIONINE SULFOXIMINE; CYTOCHROME P450 2E1; GLUTATHIONE; GLYCIDAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN CACO 2; CELL STRAIN V 79; CELL VIABILITY; COMET ASSAY; CYTOTOXICITY; DNA DAMAGE; DNA STRAND BREAKAGE; GENOTOXICITY; LIVER CELL; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ACRYLAMIDE; ANIMALS; BLOTTING, WESTERN; CACO-2 CELLS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; COMET ASSAY; CRICETINAE; CRICETULUS; CYTOCHROME P-450 CYP2E1; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOXY COMPOUNDS; GLUTATHIONE; HEPATOCYTES; HUMANS; MUTAGENS; RATS; TIME FACTORS;

MAMMALIA;

EID: 12744259430     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2004.11.009     Document Type: Article

References (32)

1. E. Tareke, P. Rydberg, P. Karlsson, S. Eriksson, and M. Törnqvist Acrylamide: a cooking carcinogen? Chem. Res. Toxicol. 13 2000 517 522
2. E. Tareke, P. Rydberg, P. Karlsson, S. Eriksson, and M. Törnqvist Analysis of acrylamide, a carcinogen formed in heated foodstuffs J. Agric. Food Chem. 50 2002 4998 5006
3. R.H. Stadler, I. Blank, N. Varga, F. Robert, J. Hau, P.A. Guy, M.-C. Robert, and S. Riediker Acrylamide from Maillard reaction products Nature 419 2002 449
4. R. Weißhaar, and B. Gutsche Formation of acrylamide in heated potato products - model experiments pointing out asparagine as precursor Deutsche Lebensmittel-Rundschau 11 2002 397 400
5. M. Granvogl, M. Jezussek, P. Koehler, and P. Schieberle Quantitation of 3-aminopropionamide in potatoes - a minor but potent precursor in acrylamide formation J. Agric. Food Chem. 52 15 2004 4751 4757
6. S. Madle, L. Broschinski, O. Mosbach-Schulz, G. Schöning, and A. Schulte Zur aktuellen Risikobewertung von Acrylamid in Lebensmitteln Bundesgesundheitsbl-Gesundheitsforsch-Gesundheitsschutz 5 2003 405 415
7. A.C. Godin, B. Bengtsson, R. Niskanen, E. Tareke, M. Törnqvist, K. Forslund, and Acrylamide N-methylolacrylamide poisoning in a herd of Charolais crossbreed cattle Vet. Rec. 151 24 2002 724 728
8. J.D. Burek, R.R. Albee, J.E. Beyer, T.J. Bell, R.M. Carreon, D.C. Morden, C.E. Wade, E.A. Hermann, and S.J. Gorzinski Subchronic toxicity of acrylamide administered to rats in the drinking water followed by up to 144 days of recover J. Environ. Pathol. Toxicol. 4 5-6 1980 157 182
9. M.B. Abou-Donia, S.M. Ibrahim, J.J. Corcoran, L. Lack, M.A. Friedman, and D.M. Lapadula Neurotoxicity of glycidamide, an acrylamide metabolite, following intraperitoneal injections in rats J. Environ. Pathol. Toxicol. 39 4 1993 447 464
10. R.M. LoPachin, C.D. Balaban, and J.F. Ross Acrylamide axonopathy revisited Toxicol. Appl. Pharmacol. 188 3 2003 135 153
11. K.A. Johnson, S.J. Gorzinski, K.M. Bodner, R.A. Campbell, C.H. Wolf, M.A. Friedman, and R.W. Mast Chronic toxicity and oncogenicity study on acrylamide incorporated in the drinking water of Fischer 344 rats Toxicol. Appl. Pharmacol. 85 2 1986 154 168
12. M.A. Friedman, L.H. Dulak, and M.A. Stedham A lifetime oncogenicity study in rats with acrylamide Fundam. Appl. Toxicol. 27 1 1995 95 105
13. IARC Monographs on the evaluation of carcinogen risks to humans: some industrial chemicals, No. 60, International Agency for Research on Cancer, Lyon, 1994.
14. G.A. Sega, and E.E. Generoso Measurement of DNA breakage in specific germ-cell stages of male mice exposed to acrylamide, using an alkaline-elution procedure Mutat. Res. 242 1990 79 87
15. K.L. Dearfield, G.R. Douglas, U.H. Ehling, M.M. Moore, G.A. Sega, and D.J. Brusick Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk Mutat. Res. 330 1-2 1995 71 99
16. 14C]acrylamide Carcinogenesis 16 1995 1161 1165
17. J.J. Solomon, J. Fedyk, F. Mukai, and A. Segal Direct alkylation of 2′-desoxynucleosides and DNA following in vitro reactions with acrylamide Cancer Res. 45 1985 3465 3470
18. C.J. Calleman, E. Bergmark, and L.G. Costa Acrylamide is metabolized to glycidamide in the rat: evidence from hemoglobin adduct formation Chem. Res. Toxicol. 3 1990 406 412
19. S.C.J. Sumner, T.R. Fennell, T.A. Moore, B. Chanas, F. Gonzalez, and B.I. Ghanayem Role of cytochrome P4502E1 in the metabolism of acrylamide and acrylonitrile in mice Chem. Res. Toxicol. 12 1999 1110 1116
20. B. Paulsson, N. Kotova, J. Grawé, A. Henderson, F. Granath, B. Golding, and M. Törnqvist Induction of micronuclei in mouse and rat by glycidamide, genotoxic metabolite of acrylamide Mutat. Res. 535 2003 13 24
21. G.G. da Costa, M.I. Churchwell, L.P. Hamilton, L.S. Von Tungeln, F.A. Beland, M.M. Marques, and D.R. Doerge DNA adduct formation from acrylamide via conversion to glycidamide in adult and neonatal mice Chem. Res. Toxicol. 16 2003 1328 1337
22. G.B. Payne, and P.H. Williams Reactions of peroxide. VI. Alkaline epoxidation of acrylonitrile J. Org. Chem. 26 1961 651 659
23. H.J. Schmitz, A. Hagenmaier, H.P. Hagenmaier, K.W. Bock, and D. Schrenk Potency of mixtures of polychlorinated biphenyls as inducers of dioxin receptor-regulated CYP1A activity in rat hepatocytes and H4IIE cells Toxicology 99 1995 47 54
24. C.M. Gedik, S.W. Ewen, and A.R. Collins Single-cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells Int. J. Radiat. Biol. 62 3 1992 313 320
25. D. Binda, D. Lasserre-Bigot, A. Bet, M. Thomassin, M.P. Come, C. Guinchard, R. Bars, A. Jacqueson, and L. Richert Time course of cytochrome P450 decline during rat hepatocyte isolation and culture: effect of L-NAME Toxicol. In Vitro 17 2003 59 67
26. M.E. Awad, M.S. Abdel-Rahman, and S.A. Hassan Acrylamide toxicity in isolated rat hepatocytes Toxicol. In Vitro 12 1998 699 704
27. 13C nuclear magnetic resonance spectroscopy Chem. Res. Toxicol. 5 1992 81 89
28. E. Zeiger, B. Anderson, S. Haworth, T. Lawlor, K. Mortelmans, and W. Speck Salmonella mutagenicity tests. III. Results from the testing of 255 chemicals Envrion. Mutagen. 9 Suppl. 9 1987 1 110
29. A.G. Knaap, P.G. Kramers, C.E. Voogd, W.G. Bergkamp, M.G. Groot, P.G. Langebroek, H.C. Mout, J.J. van der Stel, and H.W. Verharen Mutagenic activity of acrylamide in eukaryotic systems but not in bacteria Mutagenesis 3 3 1988 263 268
30. H. Tsuda, C.S. Shimizu, M.K. Taketomi, M.M. Hasegawa, A. Hamada, K.M. Kawata, and N. Inui Acrylamide; induction of DNA damage, chromosomal aberrations and cell transformation without gene mutations Mutagenesis 8 1 1993 23 29
31. A. Besaratinia, and G.P. Pfeifer Weak yet distinct mutagenicity of acrylamide in mammalian cells J. Natl. Cancer Inst. 95 2003 889 896
32. J. Park, L.M. Kamendulis, M.A. Friedman, and J.E. Klaunig Acrylamide-induced cellular transformation Toxicol. Sci. 65 2002 177 183