Analytical approaches for monitoring exposure to organophosphorus and carbamate agents through analysis of protein adducts

Drug Testing and Analysis

Volumn 4, Issue 3-4, 2012, Pages 246-261

  Schopfer, Lawrence M ^a   Lockridge, Oksana ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Forensic analysis; Low dose exposure; Mass spectrometry; Proteolysis; Retrospective analysis

Indexed keywords

AMINO ACIDS; FLUORINE COMPOUNDS; FORENSIC SCIENCE; GAS CHROMATOGRAPHY; PATIENT TREATMENT; POTASSIUM COMPOUNDS; PROTEINS;

AGENT AGES; ANALYTICAL APPROACH; BUTYRYLCHOLINESTERASE; COVALENT BINDING; FORENSIC ANALYSIS; GASCHROMATOGRAPHY-MASS SPECTROMETRY; LOW-DOSE EXPOSURES; PROTEIN ADDUCTS; RETROSPECTIVE ANALYSIS; SENSITIVE METHOD;

MASS SPECTROMETRY;

ALBUMIN; CARBAMIC ACID; CARBARIL; CHLORPYRIFOS; CHOLINESTERASE; CYCLOSARIN; DICHLORVOS; MALAOXON; MIPAFOX; ORGANOPHOSPHORUS COMPOUND; OXIME; PARAOXON; POTASSIUM FLUORIDE; SARIN; SERINE; SOMAN; TABUN; TYROSINE;

ANALYTIC METHOD; CHEMICAL REACTION; CIRCULATION; COVALENT BOND; DRUG EXPOSURE; ENZYME BINDING; GAS CHROMATOGRAPHY; HUMAN; INTOXICATION; MASS SPECTROMETER; MASS SPECTROMETRY; METABOLITE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; REVIEW;

EID: 84859426721     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.1325     Document Type: Review

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