The Mipafox-Inhibited Catalytic Domain of Human Neuropathy Target Esterase Ages by Reversible Proton Loss

Biochemistry

Volumn 43, Issue 12, 2004, Pages 3716-3722

  Kropp, Timothy J ^a   Glynn, Paul ^b   Richardson, Rudy J ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; MASS SPECTROMETRY; NEUROLOGY; ORGANIC COMPOUNDS; REACTION KINETICS;

DEPROTONATION; REVERSIBLE PROTON LOSS;

ENZYMES;

AMINE; DYFLOS; ENZYME INHIBITOR; ISOPROPYLAMINE; MIPAFOX; NEUROTOXIC ESTERASE; ORGANOPHOSPHORUS COMPOUND; UNCLASSIFIED DRUG;

AGING; ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; ENZYME ACTIVE SITE; ENZYME INHIBITION; MASS SPECTROMETRY; NEUROPATHY; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTON TRANSPORT;

AMINO ACID SEQUENCE; CARBOXYLIC ESTER HYDROLASES; CATALYTIC DOMAIN; ENZYME INHIBITORS; ENZYME REACTIVATORS; HUMANS; ISOFLUROPHATE; KINETICS; MOLECULAR SEQUENCE DATA; NERVE DEGENERATION; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHATIDYLCHOLINES; PROTONS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 1642283190     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049960e     Document Type: Article

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