Detection of human butyrylcholinesterase-nerve gas adducts by liquid chromatography-mass spectrometric analysis after in gel chymotryptic digestion

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 838, Issue 1, 2006, Pages 21-30

  Tsuge, Kouichiro ^a   Seto, Yasuo ^a  

^a NATIONAL RESEARCH INSTITUTE OF POLICE SCIENCE   (Japan)

Author keywords

Adduct; Butyrylcholinesterase; Chymotryptic digestion; LC MS; Nerve gas

Indexed keywords

AFFINITY CHROMATOGRAPHY; ELECTROPHORESIS; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR WEIGHT; POLYACRYLATES; PURIFICATION; STRUCTURE (COMPOSITION);

ADDUCT; BUTYRYLCHOLINESTERASE; CHYMOTRYPTIC DIGESTION; ELECTROSPRAY MASS SPECTROMETRY (ESI-MS); NERVE GAS;

ENZYMES;

AMINO ACID; CHOLINESTERASE; CHYMOTRYPSIN; DODECYL SULFATE SODIUM; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; NERVE GAS; PEPTIDE; PROCAINAMIDE; SARIN; SOMAN;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANALYTIC METHOD; ARTICLE; DNA ADDUCT; ELECTROSPRAY MASS SPECTROMETRY; ENZYME DEGRADATION; EXTRACTION; GEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INCUBATION TIME; MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION;

AMINO ACID SEQUENCE; BUTYRYLCHOLINESTERASE; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHYMOTRYPSIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; ORGANOTHIOPHOSPHORUS COMPOUNDS; SARIN; SOMAN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33744784002     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.02.054     Document Type: Article

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