Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: Mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis

Chemical Research in Toxicology

Volumn 24, Issue 6, 2011, Pages 797-808

  Carletti, Eugénie ^a   Schopfer, Lawrence M ^b   Colletier, Jacques Philippe ^a   Froment, Marie Thérèse ^c   Nachon, Florian ^c   Weik, Martin ^a   Lockridge, Oksana ^b   Masson, Patrick ^a,b,c  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c CENTRE DE RECHERCHES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINESTERASE; CRESYL SALIGENIN PHOSPHATE; ORGANOPHOSPHATE; UNCLASSIFIED DRUG;

AEROTOXIC SYNDROME; AGING; AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; INTOXICATION; MASS SPECTROMETRY; PROTEIN PHOSPHORYLATION;

ACETYLCHOLINESTERASE; AIR POLLUTION, INDOOR; AIRCRAFT; BUTYRYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; CRYSTALLOGRAPHY, X-RAY; HUMANS; KINETICS; MASS SPECTROMETRY; MODELS, MOLECULAR; NEUROTOXICITY SYNDROMES; ORGANOPHOSPHORUS COMPOUNDS; PERIPHERAL NERVOUS SYSTEM DISEASES;

EID: 79959401336     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx100447k     Document Type: Article

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