-
1
-
-
0026526437
-
E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
-
PMID:1411535
-
Nevins JR. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 1992; 258:424-9; PMID:1411535; http://dx.doi.org/10.1126/ science.1411535.
-
(1992)
Science
, vol.258
, pp. 424-429
-
-
Nevins, J.R.1
-
2
-
-
0027382336
-
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein
-
PMID:8413249
-
Helin K, Harlow E, Fattaey A. Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. Mol Cell Biol 1993; 13:6501-8; PMID:8413249.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6501-6508
-
-
Helin, K.1
Harlow, E.2
Fattaey, A.3
-
3
-
-
0027140404
-
Cell cycle-specific association of E2F with the p130 E1A-binding protein
-
PMID:8253385
-
Cobrinik D, Whyte P, Peeper DS, Jacks T, Weinberg RA. Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes Dev 1993; 7:2392-404; PMID:8253385; http://dx.doi.org/10.1101/gad.7.12a.2392.
-
(1993)
Genes Dev
, vol.7
, pp. 2392-2404
-
-
Cobrinik, D.1
Whyte, P.2
Peeper, D.S.3
Jacks, T.4
Weinberg, R.A.5
-
4
-
-
0026530730
-
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner
-
PMID:1531040
-
Shirodkar S, Ewen M, DeCaprio JA, Morgan J, Livingston DM, Chittenden T. The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell 1992; 68:157-66; PMID:1531040; http:// dx.doi.org/10.1016/0092-8674(92)90214-W.
-
(1992)
Cell
, vol.68
, pp. 157-166
-
-
Shirodkar, S.1
Ewen, M.2
DeCaprio, J.A.3
Morgan, J.4
Livingston, D.M.5
Chittenden, T.6
-
6
-
-
0026609875
-
Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F
-
PMID:1530885
-
Cao L, Faha B, Dembski M, Tsai LH, Harlow E, Dyson N. Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature 1992; 355:176-9; PMID:1530885; http://dx.doi.org/10.1038/355176a0.
-
(1992)
Nature
, vol.355
, pp. 176-179
-
-
Cao, L.1
Faha, B.2
Dembski, M.3
Tsai, L.H.4
Harlow, E.5
Dyson, N.6
-
7
-
-
0025734783
-
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
-
PMID:1828394
-
Chittenden T, Livingston DM, Kaelin WG Jr. The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell 1991; 65:1073-82; PMID:1828394; http://dx.doi.org/10. 1016/0092-8674(91)90559-H.
-
(1991)
Cell
, vol.65
, pp. 1073-1082
-
-
Chittenden, T.1
Livingston, D.M.2
Kaelin Jr., W.G.3
-
8
-
-
0025905183
-
The E2F transcription factor is a cellular target for the RB protein
-
PMID:1828392
-
Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR. The E2F transcription factor is a cellular target for the RB protein. Cell 1991; 65:1053-61; PMID:1828392; http://dx.doi.org/10.1016/0092-8674(91)90557-F.
-
(1991)
Cell
, vol.65
, pp. 1053-1061
-
-
Chellappan, S.P.1
Hiebert, S.2
Mudryj, M.3
Horowitz, J.M.4
Nevins, J.R.5
-
9
-
-
0025869428
-
Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor
-
PMID:1710781
-
Bandara LR, La Thangue NB. Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature 1991; 351:494-7; PMID:1710781; http://dx.doi.org/10.1038/351494a0.
-
(1991)
Nature
, vol.351
, pp. 494-497
-
-
Bandara, L.R.1
La Thangue, N.B.2
-
10
-
-
0025910802
-
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F
-
PMID:1828393
-
Bagchi S, Weinmann R, Raychaudhuri P. The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F. Cell 1991; 65:1063-72; PMID:1828393; http://dx.doi.org/10.1016/0092- 8674(91)90558-G.
-
(1991)
Cell
, vol.65
, pp. 1063-1072
-
-
Bagchi, S.1
Weinmann, R.2
Raychaudhuri, P.3
-
11
-
-
0025893161
-
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A
-
PMID:1829647
-
Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR. Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell 1991; 65:1243-53; PMID:1829647; http://dx.doi.org/10.1016/0092-8674(91) 90019-U.
-
(1991)
Cell
, vol.65
, pp. 1243-1253
-
-
Mudryj, M.1
Devoto, S.H.2
Hiebert, S.W.3
Hunter, T.4
Pines, J.5
Nevins, J.R.6
-
12
-
-
0027299921
-
Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F
-
PMID:8321204
-
Chittenden T, Livingston DM, DeCaprio JA. Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F. Mol Cell Biol 1993; 13:3975-83; PMID:8321204.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 3975-3983
-
-
Chittenden, T.1
Livingston, D.M.2
DeCaprio, J.A.3
-
13
-
-
0028919678
-
In vivo association of E2F and DP family proteins
-
PMID:7739537
-
Wu CL, Zukerberg LR, Ngwu C, Harlow E, Lees JA. In vivo association of E2F and DP family proteins. Mol Cell Biol 1995; 15:2536-46; PMID:7739537.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2536-2546
-
-
Wu, C.L.1
Zukerberg, L.R.2
Ngwu, C.3
Harlow, E.4
Lees, J.A.5
-
14
-
-
0027769885
-
Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members
-
PMID:8248803
-
Krek W, Livingston DM, Shirodkar S. Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science 1993; 262:1557-60; PMID:8248803; http://dx.doi.org/10.1126/science. 8248803.
-
(1993)
Science
, vol.262
, pp. 1557-1560
-
-
Krek, W.1
Livingston, D.M.2
Shirodkar, S.3
-
15
-
-
0027426917
-
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation
-
PMID:8405995
-
Helin K, Wu CL, Fattaey AR, Lees JA, Dynlacht BD, Ngwu C, et al. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev 1993; 7:1850-61; PMID:8405995; http://dx.doi.org/10.1101/gad.7.10.1850.
-
(1993)
Genes Dev
, vol.7
, pp. 1850-1861
-
-
Helin, K.1
Wu, C.L.2
Fattaey, A.R.3
Lees, J.A.4
Dynlacht, B.D.5
Ngwu, C.6
-
16
-
-
0027434084
-
Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F
-
PMID:8223441
-
Bandara LR, Buck VM, Zamanian M, Johnston LH, La Thangue NB. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J 1993; 12:4317-24; PMID:8223441.
-
(1993)
EMBO J
, vol.12
, pp. 4317-4324
-
-
Bandara, L.R.1
Buck, V.M.2
Zamanian, M.3
Johnston, L.H.4
La Thangue, N.B.5
-
17
-
-
0027440919
-
A new component of the transcription factor DRTF1/E2F
-
PMID:8413592
-
Girling R, Partridge JF, Bandara LR, Burden N, Totty NF, Hsuan JJ, et al. A new component of the transcription factor DRTF1/E2F. Nature 1993; 365:468; PMID:8413592; http://dx.doi.org/10.1038/365468d0.
-
(1993)
Nature
, vol.365
, pp. 468
-
-
Girling, R.1
Partridge, J.F.2
Bandara, L.R.3
Burden, N.4
Totty, N.F.5
Hsuan, J.J.6
-
18
-
-
50149120366
-
Cellular mechanisms of tumour suppression by the retinoblastoma gene
-
PMID:18650841
-
Burkhart DL, Sage J. Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat Rev Cancer 2008; 8:671-82; PMID:18650841; http:// dx.doi.org/10.1038/nrc2399.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 671-682
-
-
Burkhart, D.L.1
Sage, J.2
-
19
-
-
0039227088
-
Induction of S-phase entry by E2F transcription factors depends on their nuclear localization
-
PMID:9271426
-
Müller H, Moroni MC, Vigo E, Petersen BO, Bartek J, Helin K. Induction of S-phase entry by E2F transcription factors depends on their nuclear localization. Mol Cell Biol 1997; 17:5508-20; PMID:9271426.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5508-5520
-
-
Müller, H.1
Moroni, M.C.2
Vigo, E.3
Petersen, B.O.4
Bartek, J.5
Helin, K.6
-
20
-
-
18344390418
-
ERBB receptors and cancer: The complexity of targeted inhibitors
-
PMID:15864276
-
Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005; 5:341-54; PMID:15864276; http://dx.doi.org/10. 1038/nrc1609.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
21
-
-
0035256698
-
Untangling the ErbB signalling network
-
PMID:11252954
-
Yarden Y, Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2001; 2:127-37; PMID:11252954; http://dx.doi.org/10.1038/35052073.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 127-137
-
-
Yarden, Y.1
Sliwkowski, M.X.2
-
22
-
-
60749109846
-
Cell cycle, CDKs and cancer: A changing paradigm
-
PMID:19238148
-
Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 2009; 9:153-66; PMID:19238148; http://dx.doi.org/10. 1038/nrc2602.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
23
-
-
27544470656
-
Mammalian cyclin-dependent kinases
-
PMID:16236519
-
Malumbres M, Barbacid M. Mammalian cyclin-dependent kinases. Trends Biochem Sci 2005; 30:630-41; PMID:16236519; http://dx.doi.org/10.1016/j.tibs. 2005.09.005.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 630-641
-
-
Malumbres, M.1
Barbacid, M.2
-
24
-
-
0035754080
-
To cycle or not to cycle: A critical decision in cancer
-
PMID:11902577
-
Malumbres M, Barbacid M. To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer 2001; 1:222-31; PMID:11902577; http://dx.doi.org/10. 1038/35106065.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 222-231
-
-
Malumbres, M.1
Barbacid, M.2
-
25
-
-
0034306996
-
The Rb/E2F pathway: Expanding roles and emerging paradigms
-
PMID:11018009
-
Harbour JW, Dean DC. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev 2000; 14:2393-409; PMID:11018009; http://dx.doi.org/10. 1101/gad.813200.
-
(2000)
Genes Dev
, vol.14
, pp. 2393-2409
-
-
Harbour, J.W.1
Dean, D.C.2
-
26
-
-
0035063183
-
The Rb/E2F pathway and cancer
-
PMID:11257102
-
Nevins JR. The Rb/E2F pathway and cancer. Hum Mol Genet 2001; 10:699-703; PMID:11257102; http:// dx.doi.org/10.1093/hmg/10.7.699.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 699-703
-
-
Nevins, J.R.1
-
27
-
-
1542426648
-
Amplification and overexpression of E2F3 in human bladder cancer
-
PMID:14716298
-
Feber A, Clark J, Goodwin G, Dodson AR, Smith PH, Fletcher A, et al. Amplification and overexpression of E2F3 in human bladder cancer. Oncogene 2004; 23:1627-30; PMID:14716298; http://dx.doi.org/10.1038/sj.onc.1207274.
-
(2004)
Oncogene
, vol.23
, pp. 1627-1630
-
-
Feber, A.1
Clark, J.2
Goodwin, G.3
Dodson, A.R.4
Smith, P.H.5
Fletcher, A.6
-
28
-
-
42549109141
-
Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification
-
PMID:18037967
-
Hurst CD, Tomlinson DC, Williams SV, Platt FM, Knowles MA. Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification. Oncogene 2008; 27:2716-27; PMID:18037967; http://dx.doi.org/10.1038/sj.onc.1210934.
-
(2008)
Oncogene
, vol.27
, pp. 2716-2727
-
-
Hurst, C.D.1
Tomlinson, D.C.2
Williams, S.V.3
Platt, F.M.4
Knowles, M.A.5
-
29
-
-
27144521756
-
Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma
-
PMID:16007192
-
Grasemann C, Gratias S, Stephan H, Schüler A, Schramm A, Klein-Hitpass L, et al. Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma. Oncogene 2005; 24:6441-9; PMID:16007192.
-
(2005)
Oncogene
, vol.24
, pp. 6441-6449
-
-
Grasemann, C.1
Gratias, S.2
Stephan, H.3
Schüler, A.4
Schramm, A.5
Klein-Hitpass, L.6
-
30
-
-
33644881673
-
Expression analysis of 6p22 genomic gain in retinoblastoma
-
PMID:16180235
-
Orlic M, Spencer CE, Wang L, Gallie BL. Expression analysis of 6p22 genomic gain in retinoblastoma. Genes Chromosomes Cancer 2006; 45:72-82; PMID:16180235; http://dx.doi.org/10.1002/gcc.20263.
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 72-82
-
-
Orlic, M.1
Spencer, C.E.2
Wang, L.3
Gallie, B.L.4
-
31
-
-
33750900241
-
Retinoblastoma regulatory pathway in lung cancer
-
PMID:17100603
-
Wikenheiser-Brokamp KA. Retinoblastoma regulatory pathway in lung cancer. Curr Mol Med 2006; 6:783-93; PMID:17100603.
-
(2006)
Curr Mol Med
, vol.6
, pp. 783-793
-
-
Wikenheiser-Brokamp, K.A.1
-
32
-
-
0034425049
-
Loss-of- Heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays
-
PMID:10973224
-
Lindblad-Toh K, Tanenbaum DM, Daly MJ, Winchester E, Lui WO, Villapakkam A, et al. Loss-of- heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays. Nat Biotechnol 2000; 18:1001-5; PMID:10973224; http:// dx.doi.org/10.1038/79269.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 1001-1005
-
-
Lindblad-Toh, K.1
Tanenbaum, D.M.2
Daly, M.J.3
Winchester, E.4
Lui, W.O.5
Villapakkam, A.6
-
33
-
-
33751120208
-
Nuclear overexpression of the E2F3 transcription factor in human lung cancer
-
PMID:16938365
-
Cooper CS, Nicholson AG, Foster C, Dodson A, Edwards S, Fletcher A, et al. Nuclear overexpression of the E2F3 transcription factor in human lung cancer. Lung Cancer 2006; 54:155-62; PMID:16938365; http://dx.doi.org/10.1016/j. lungcan.2006.07.005.
-
(2006)
Lung Cancer
, vol.54
, pp. 155-162
-
-
Cooper, C.S.1
Nicholson, A.G.2
Foster, C.3
Dodson, A.4
Edwards, S.5
Fletcher, A.6
-
34
-
-
33746610140
-
Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF
-
PMID:16835303
-
Qin G, Kishore R, Dolan CM, Silver M, Wecker A, Luedemann CN, et al. Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF. Proc Natl Acad Sci USA 2006; 103:11015-20; PMID:16835303; http://dx.doi.org/10.1073/pnas.0509533103.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11015-11020
-
-
Qin, G.1
Kishore, R.2
Dolan, C.M.3
Silver, M.4
Wecker, A.5
Luedemann, C.N.6
-
35
-
-
50649086353
-
Mouse development with a single E2F activator
-
PMID:18594513
-
Tsai SY, Opavsky R, Sharma N, Wu L, Naidu S, Nolan E, et al. Mouse development with a single E2F activator. Nature 2008; 454:1137-41; PMID:18594513; http://dx.doi.org/10.1038/nature07066.
-
(2008)
Nature
, vol.454
, pp. 1137-1141
-
-
Tsai, S.Y.1
Opavsky, R.2
Sharma, N.3
Wu, L.4
Naidu, S.5
Nolan, E.6
-
36
-
-
0036069979
-
E2Fs regulate adipocyte differentiation
-
PMID:12110166
-
Fajas L, Landsberg RL, Huss-Garcia Y, Sardet C, Lees JA, Auwerx J. E2Fs regulate adipocyte differentiation. Dev Cell 2002; 3:39-49; PMID:12110166; http:// dx.doi.org/10.1016/S1534-5807(02)00190-9.
-
(2002)
Dev Cell
, vol.3
, pp. 39-49
-
-
Fajas, L.1
Landsberg, R.L.2
Huss-Garcia, Y.3
Sardet, C.4
Lees, J.A.5
Auwerx, J.6
-
37
-
-
0035265833
-
dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development
-
PMID:11463372
-
Ceol CJ, Horvitz HR. dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Mol Cell 2001; 7:461-73; PMID:11463372; http://dx.doi.org/10.1016/S1097-2765(01)00194-0.
-
(2001)
Mol Cell
, vol.7
, pp. 461-473
-
-
Ceol, C.J.1
Horvitz, H.R.2
-
38
-
-
11244252136
-
Lin-35 Rb acts in the major hypodermis to oppose ras-mediated vulval induction in C. elegans
-
PMID:15621535
-
Myers TR, Greenwald I. lin-35 Rb acts in the major hypodermis to oppose ras-mediated vulval induction in C. elegans. Dev Cell 2005; 8:117-23; PMID:15621535; http://dx.doi.org/10.1016/j.devcel.2004.11.015.
-
(2005)
Dev Cell
, vol.8
, pp. 117-123
-
-
Myers, T.R.1
Greenwald, I.2
-
39
-
-
0032939925
-
Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
-
PMID:10207094
-
Blattner C, Sparks A, Lane D. Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol Cell Biol 1999; 19:3704-13; PMID:10207094.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3704-3713
-
-
Blattner, C.1
Sparks, A.2
Lane, D.3
-
40
-
-
73549095168
-
E2F3 is a mediator of DNA damage- Induced apoptosis
-
PMID:19917728
-
Martinez LA, Goluszko E, Chen HZ, Leone G, Post S, Lozano G, et al. E2F3 is a mediator of DNA damage- induced apoptosis. Mol Cell Biol 2010; 30:524-36; PMID:19917728; http://dx.doi.org/10.1128/MCB.00938-09.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 524-536
-
-
Martinez, L.A.1
Goluszko, E.2
Chen, H.Z.3
Leone, G.4
Post, S.5
Lozano, G.6
-
41
-
-
34247199852
-
Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage
-
PMID:17380128
-
Inoue Y, Kitagawa M, Taya Y. Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage. EMBO J 2007; 26:2083-93; PMID:17380128; http://dx.doi.org/10.1038/sj.emboj.7601652.
-
(2007)
EMBO J
, vol.26
, pp. 2083-2093
-
-
Inoue, Y.1
Kitagawa, M.2
Taya, Y.3
-
42
-
-
0026769912
-
Transcriptional repression of the E2-containing promoters EIIaE, c-myc and RB1 by the product of the RB1 gene
-
PMID:1385853
-
Hamel PA, Gill RM, Phillips RA, Gallie BL. Transcriptional repression of the E2-containing promoters EIIaE, c-myc and RB1 by the product of the RB1 gene. Mol Cell Biol 1992; 12:3431-8; PMID:1385853.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3431-3438
-
-
Hamel, P.A.1
Gill, R.M.2
Phillips, R.A.3
Gallie, B.L.4
-
43
-
-
0026636908
-
Retinoblastoma protein switches the E2F site from positive to negative element
-
PMID:1321348
-
Weintraub SJ, Prater CA, Dean DC. Retinoblastoma protein switches the E2F site from positive to negative element. Nature 1992; 358:259-61; PMID:1321348; http://dx.doi.org/10.1038/358259a0.
-
(1992)
Nature
, vol.358
, pp. 259-261
-
-
Weintraub, S.J.1
Prater, C.A.2
Dean, D.C.3
-
44
-
-
0028960617
-
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
-
PMID:7884898
-
Kowalik TF, DeGregori J, Schwarz JK, Nevins JR. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J Virol 1995; 69:2491-500; PMID:7884898.
-
(1995)
J Virol
, vol.69
, pp. 2491-2500
-
-
Kowalik, T.F.1
DeGregori, J.2
Schwarz, J.K.3
Nevins, J.R.4
-
45
-
-
0028222124
-
p53 and E2F-1 cooperate to mediate apoptosis
-
PMID:8170954
-
Wu X, Levine AJ. p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci USA 1994; 91:3602-6; PMID:8170954; http://dx.doi.org/10.1073/pnas.91.9. 3602.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3602-3606
-
-
Wu, X.1
Levine, A.J.2
-
46
-
-
0027947383
-
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
-
PMID:7971984
-
Qin XQ, Livingston DM, Kaelin WG Jr, Adams PD. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci USA 1994; 91:10918-22; PMID:7971984; http://dx.doi.org/10.1073/ pnas.91.23.10918.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10918-10922
-
-
Qin, X.Q.1
Livingston, D.M.2
Kaelin Jr., W.G.3
Adams, P.D.4
-
47
-
-
0028061670
-
Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
-
PMID:7969153
-
Shan B, Lee WH. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol Cell Biol 1994; 14:8166-73; PMID:7969153.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 8166-8173
-
-
Shan, B.1
Lee, W.H.2
-
48
-
-
0031992159
-
E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2
-
PMID:9486847
-
Kowalik TF, DeGregori J, Leone G, Jakoi L, Nevins JR. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ 1998; 9:113-8; PMID:9486847.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 113-118
-
-
Kowalik, T.F.1
DeGregori, J.2
Leone, G.3
Jakoi, L.4
Nevins, J.R.5
-
49
-
-
0030739355
-
Induction of DNA synthesis and apoptosis are separable functions of E2F-1
-
PMID:9242492
-
Phillips AC, Bates S, Ryan KM, Helin K, Vousden KH. Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev 1997; 11:1853-63; PMID:9242492; http://dx.doi.org/10.1101/gad.11.14.1853.
-
(1997)
Genes Dev
, vol.11
, pp. 1853-1863
-
-
Phillips, A.C.1
Bates, S.2
Ryan, K.M.3
Helin, K.4
Vousden, K.H.5
-
50
-
-
0032622050
-
p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin
-
PMID:9863003
-
Meng RD, Phillips P, El-Deiry WS. p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin. Int J Oncol 1999; 14:5-14; PMID:9863003.
-
(1999)
Int J Oncol
, vol.14
, pp. 5-14
-
-
Meng, R.D.1
Phillips, P.2
El-Deiry, W.S.3
-
51
-
-
0345299171
-
Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation
-
PMID:9862970
-
Höfferer M, Wirbelauer C, Humar B, Krek W. Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation. Nucleic Acids Res 1999; 27:491-5; PMID:9862970; http://dx.doi.org/10.1093/nar/27.2.491.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 491-495
-
-
Höfferer, M.1
Wirbelauer, C.2
Humar, B.3
Krek, W.4
-
52
-
-
10644270921
-
p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
-
PMID:15601819
-
Urist M, Tanaka T, Poyurovsky MV, Prives C. p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes Dev 2004; 18:3041-54; PMID:15601819; http://dx.doi.org/10.1101/gad.1221004.
-
(2004)
Genes Dev
, vol.18
, pp. 3041-3054
-
-
Urist, M.1
Tanaka, T.2
Poyurovsky, M.V.3
Prives, C.4
-
53
-
-
0038752083
-
Chk2 activates E2F-1 in response to DNA damage
-
PMID:12717439
-
Stevens C, Smith L, La Thangue NB. Chk2 activates E2F-1 in response to DNA damage. Nat Cell Biol 2003; 5:401-9; PMID:12717439; http://dx.doi.org/10. 1038/ncb974.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 401-409
-
-
Stevens, C.1
Smith, L.2
La Thangue, N.B.3
-
54
-
-
0035878122
-
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
-
PMID:11459832
-
Lin WC, Lin FT, Nevins JR. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev 2001; 15:1833-44; PMID:11459832.
-
(2001)
Genes Dev
, vol.15
, pp. 1833-1844
-
-
Lin, W.C.1
Lin, F.T.2
Nevins, J.R.3
-
55
-
-
0030828886
-
Role for E2F in DNA damage-induced entry of cells into S phase
-
PMID:9288762
-
Huang Y, Ishiko T, Nakada S, Utsugisawa T, Kato T, Yuan ZM. Role for E2F in DNA damage-induced entry of cells into S phase. Cancer Res 1997; 57:3640-3; PMID:9288762.
-
(1997)
Cancer Res
, vol.57
, pp. 3640-3643
-
-
Huang, Y.1
Ishiko, T.2
Nakada, S.3
Utsugisawa, T.4
Kato, T.5
Yuan, Z.M.6
-
56
-
-
58549112996
-
Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
-
PMID:19033363
-
Huang W, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 2009; 37:1-13; PMID:19033363; http://dx.doi.org/10.1093/nar/gkn923.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1-13
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
57
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
PMID:19131956
-
Huang W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009; 4:44-57; PMID:19131956; http://dx.doi.org/10.1038/nprot.2008.211.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
58
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
PMID:18001825
-
Huen MS, Grant R, Manke I, Minn K, Yu X, Yaffe MB, et al. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 2007; 131:901-14; PMID:18001825; http://dx.doi.org/10.1016/j. cell.2007.09.041.
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
-
59
-
-
0037068455
-
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
-
PMID:12226657
-
Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 2002; 419:135-41; PMID:12226657; http:// dx.doi.org/10.1038/nature00991.
-
(2002)
Nature
, vol.419
, pp. 135-141
-
-
Hoege, C.1
Pfander, B.2
Moldovan, G.L.3
Pyrowolakis, G.4
Jentsch, S.5
-
60
-
-
80051748549
-
RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control
-
PMID:21855804
-
Bourgo RJ, Thangavel C, Ertel A, Bergseid J, McClendon AK, Wilkens L, et al. RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control. Mol Cell 2011; 43:663-72; PMID:21855804; http:// dx.doi.org/10.1016/j.molcel.2011.06.029.
-
(2011)
Mol Cell
, vol.43
, pp. 663-672
-
-
Bourgo, R.J.1
Thangavel, C.2
Ertel, A.3
Bergseid, J.4
McClendon, A.K.5
Wilkens, L.6
-
61
-
-
0019174693
-
Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes
-
PMID:6249803
-
Wilkinson KD, Urban MK, Haas AL. Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes. J Biol Chem 1980; 255:7529-32; PMID:6249803.
-
(1980)
J Biol Chem
, vol.255
, pp. 7529-7532
-
-
Wilkinson, K.D.1
Urban, M.K.2
Haas, A.L.3
-
62
-
-
0019000271
-
Proposed role of ATP in protein breakdown: Conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis
-
PMID:6990414
-
Hershko A, Ciechanover A, Heller H, Haas AL, Rose IA. Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis. Proc Natl Acad Sci USA 1980; 77:1783-6; PMID:6990414; http://dx.doi. org/10.1073/pnas.77.4.1783.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1783-1786
-
-
Hershko, A.1
Ciechanover, A.2
Heller, H.3
Haas, A.L.4
Rose, I.A.5
-
63
-
-
0018992813
-
ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation
-
PMID:6769112
-
Ciechanover A, Heller H, Elias S, Haas AL, Hershko A. ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation. Proc Natl Acad Sci USA 1980; 77:1365-8; PMID:6769112; http://dx.doi.org/10.1073/pnas.77.3.1365.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1365-1368
-
-
Ciechanover, A.1
Heller, H.2
Elias, S.3
Haas, A.L.4
Hershko, A.5
-
64
-
-
0018772190
-
Resolution of the ATP-dependent proteolytic system from reticulocytes: A component that interacts with ATP
-
PMID:290989
-
Hershko A, Ciechanover A, Rose IA. Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP. Proc Natl Acad Sci USA 1979; 76:3107-10; PMID:290989; http://dx.doi.org/10.1073/ pnas.76.7.3107.
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 3107-3110
-
-
Hershko, A.1
Ciechanover, A.2
Rose, I.A.3
-
65
-
-
0342265782
-
A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes
-
PMID:264694
-
Etlinger JD, Goldberg AL. A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes. Proc Natl Acad Sci USA 1977; 74:54-8; PMID:264694; http://dx.doi.org/10.1073/pnas.74.1. 54.
-
(1977)
Proc Natl Acad Sci USA
, vol.74
, pp. 54-58
-
-
Etlinger, J.D.1
Goldberg, A.L.2
-
66
-
-
77049143850
-
The release of labeled amino acids from the proteins of rat liver slices
-
PMID:13044783
-
Simpson MV. The release of labeled amino acids from the proteins of rat liver slices. J Biol Chem 1953; 201:143-54; PMID:13044783.
-
(1953)
J Biol Chem
, vol.201
, pp. 143-154
-
-
Simpson, M.V.1
-
67
-
-
27144529182
-
Ubiquitylation and cell signaling
-
PMID:16148945
-
Haglund K, Dikic I. Ubiquitylation and cell signaling. EMBO J 2005; 24:3353-9; PMID:16148945; http:// dx.doi.org/10.1038/sj.emboj.7600808.
-
(2005)
EMBO J
, vol.24
, pp. 3353-3359
-
-
Haglund, K.1
Dikic, I.2
-
68
-
-
78649492271
-
The ubiquitous role of ubiquitin in the DNA damage response
-
(Amst) PMID:21056014
-
Al-Hakim A, Escribano-Diaz C, Landry MC, O'Donnell L, Panier S, Szilard RK, et al. The ubiquitous role of ubiquitin in the DNA damage response. DNA Repair (Amst) 2010; 9:1229-40; PMID:21056014; http://dx.doi.org/10.1016/j. dnarep.2010.09.011.
-
(2010)
DNA Repair
, vol.9
, pp. 1229-1240
-
-
Al-Hakim, A.1
Escribano-Diaz, C.2
Landry, M.C.3
O'Donnell, L.4
Panier, S.5
Szilard, R.K.6
-
69
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
PMID:18001824
-
Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, Lukas C, et al. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 2007; 131:887-900; PMID:18001824; http://dx.doi.org/10.1016/j.cell.2007.09.040.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
-
70
-
-
33646117239
-
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
-
PMID:16618811
-
Bekker-Jensen S, Lukas C, Kitagawa R, Melander F, Kastan MB, Bartek J, et al. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 2006; 173:195-206; PMID:16618811; http://dx.doi.org/10.1083/jcb.200510130.
-
(2006)
J Cell Biol
, vol.173
, pp. 195-206
-
-
Bekker-Jensen, S.1
Lukas, C.2
Kitagawa, R.3
Melander, F.4
Kastan, M.B.5
Bartek, J.6
-
71
-
-
67349168142
-
RAD18 transmits DNA damage signalling to elicit homologous recombination repair
-
PMID:19396164
-
Huang J, Huen MS, Kim H, Leung CC, Glover JN, Yu X, et al. RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol 2009; 11:592-603; PMID:19396164; http://dx.doi. org/10.1038/ncb1865.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 592-603
-
-
Huang, J.1
Huen, M.S.2
Kim, H.3
Leung, C.C.4
Glover, J.N.5
Yu, X.6
-
72
-
-
79956053726
-
Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis
-
PMID:21247883
-
Lee BK, Bhinge AA, Iyer VR. Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis. Nucleic Acids Res 2011; 39:3558-73; PMID:21247883; http://dx.doi.org/10.1093/ nar/gkq1313.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 3558-3573
-
-
Lee, B.K.1
Bhinge, A.A.2
Iyer, V.R.3
-
73
-
-
77956997759
-
Damage-specific modification of PCNA
-
PMID:20930510
-
Das-Bradoo S, Nguyen HD, Bielinsky AK. Damage-specific modification of PCNA. Cell Cycle 2010; 9:3674-9; PMID:20930510; http://dx.doi.org/10.4161/cc.9. 18.13121.
-
(2010)
Cell Cycle
, vol.9
, pp. 3674-3679
-
-
Das-Bradoo, S.1
Nguyen, H.D.2
Bielinsky, A.K.3
-
74
-
-
79955934251
-
Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107
-
PMID:20010813
-
Das-Bradoo S, Nguyen HD, Wood JL, Ricke RM, Haworth JC, Bielinsky AK. Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107. Nat Cell Biol 2010; 12:74-9; PMID:20010813; http://dx.doi.org/10.1038/ncb2007.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 74-79
-
-
Das-Bradoo, S.1
Nguyen, H.D.2
Wood, J.L.3
Ricke, R.M.4
Haworth, J.C.5
Bielinsky, A.K.6
-
75
-
-
2442417331
-
Interaction of human DNA polymerase eta with monoubiquitinated PCNA: A possible mechanism for the polymerase switch in response to DNA damage
-
PMID:15149598
-
Kannouche PL, Wing J, Lehmann AR. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell 2004; 14:491-500; PMID:15149598; http://dx.doi.org/10.1016/S1097-2765(04)00259-X.
-
(2004)
Mol Cell
, vol.14
, pp. 491-500
-
-
Kannouche, P.L.1
Wing, J.2
Lehmann, A.R.3
-
76
-
-
0141831006
-
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation
-
PMID:12968183
-
Stelter P, Ulrich HD. Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature 2003; 425:188-91; PMID:12968183; http://dx.doi.org/10.1038/nature01965.
-
(2003)
Nature
, vol.425
, pp. 188-191
-
-
Stelter, P.1
Ulrich, H.D.2
-
77
-
-
28844506236
-
Suffering in silence: The tolerance of DNA damage
-
PMID:16341080
-
Friedberg EC. Suffering in silence: the tolerance of DNA damage. Nat Rev Mol Cell Biol 2005; 6:943-53; PMID:16341080; http://dx.doi.org/10.1038/nrm1781.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 943-953
-
-
Friedberg, E.C.1
-
78
-
-
18844415068
-
Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae
-
PMID:15687278
-
Minesinger BK, Jinks-Robertson S. Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae. Genetics 2005; 169:1939-55; PMID:15687278; http://dx.doi.org/10. 1534/genetics.104.033894.
-
(2005)
Genetics
, vol.169
, pp. 1939-1955
-
-
Minesinger, B.K.1
Jinks-Robertson, S.2
-
79
-
-
19444383801
-
Trading places: How do DNA polymerases switch during translesion DNA synthesis?
-
PMID:15916957
-
Friedberg EC, Lehmann AR, Fuchs RP. Trading places: how do DNA polymerases switch during translesion DNA synthesis? Mol Cell 2005; 18:499-505; PMID:15916957; http://dx.doi.org/10.1016/j.molcel. 2005.03.032.
-
(2005)
Mol Cell
, vol.18
, pp. 499-505
-
-
Friedberg, E.C.1
Lehmann, A.R.2
Fuchs, R.P.3
-
80
-
-
1942439667
-
Switching from highfidelity replicases to low-fidelity lesion-bypass polymerases
-
PMID:15196456
-
Plosky BS, Woodgate R. Switching from highfidelity replicases to low-fidelity lesion-bypass polymerases. Curr Opin Genet Dev 2004; 14:113-9; PMID:15196456; http://dx.doi.org/10.1016/j.gde.2004.02.002.
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 113-119
-
-
Plosky, B.S.1
Woodgate, R.2
-
81
-
-
0942268173
-
Xeroderma pigmentosum variant and error-prone DNA polymerases
-
PMID:14726018
-
Kannouche P, Stary A. Xeroderma pigmentosum variant and error-prone DNA polymerases. Biochimie 2003; 85:1123-32; PMID:14726018; http://dx.doi.org/10. 1016/j.biochi.2003.10.009.
-
(2003)
Biochimie
, vol.85
, pp. 1123-1132
-
-
Kannouche, P.1
Stary, A.2
-
82
-
-
0035808417
-
Purification and characterization of polkappa, a DNA polymerase encoded by the human DINB1 gene
-
PMID:11024016
-
Gerlach VL, Feaver WJ, Fischhaber PL, Friedberg EC. Purification and characterization of polkappa, a DNA polymerase encoded by the human DINB1 gene. J Biol Chem 2001; 276:92-8; PMID:11024016; http:// dx.doi.org/10.1074/jbc. M004413200.
-
(2001)
J Biol Chem
, vol.276
, pp. 92-98
-
-
Gerlach, V.L.1
Feaver, W.J.2
Fischhaber, P.L.3
Friedberg, E.C.4
-
83
-
-
0035807870
-
Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA
-
PMID:11724965
-
Haracska L, Johnson RE, Unk I, Phillips BB, Hurwitz J, Prakash L, et al. Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA. Proc Natl Acad Sci USA 2001; 98:14256-61; PMID:11724965; http://dx.doi.org/10.1073/pnas.261560798.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14256-14261
-
-
Haracska, L.1
Johnson, R.E.2
Unk, I.3
Phillips, B.B.4
Hurwitz, J.5
Prakash, L.6
-
84
-
-
0034600851
-
Two RING finger proteins mediate cooperation between ubiquitin- conjugating enzymes in DNA repair
-
PMID:10880451
-
Ulrich HD, Jentsch S. Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J 2000; 19:3388-97; PMID:10880451; http://dx.doi.org/10.1093/emboj/19.13.3388.
-
(2000)
EMBO J
, vol.19
, pp. 3388-3397
-
-
Ulrich, H.D.1
Jentsch, S.2
-
85
-
-
57749169348
-
SUMOylation regulates Rad18-mediated template switch
-
PMID:19092928
-
Branzei D, Vanoli F, Foiani M. SUMOylation regulates Rad18-mediated template switch. Nature 2008; 456:915-20; PMID:19092928; http://dx.doi.org/10. 1038/nature07587.
-
(2008)
Nature
, vol.456
, pp. 915-920
-
-
Branzei, D.1
Vanoli, F.2
Foiani, M.3
-
86
-
-
0030814759
-
Involvement of the yeast DNA polymerase delta in DNA repair in vivo
-
PMID:9258670
-
Giot L, Chanet R, Simon M, Facca C, Faye G. Involvement of the yeast DNA polymerase delta in DNA repair in vivo. Genetics 1997; 146:1239-51; PMID:9258670.
-
(1997)
Genetics
, vol.146
, pp. 1239-1251
-
-
Giot, L.1
Chanet, R.2
Simon, M.3
Facca, C.4
Faye, G.5
-
87
-
-
27644590452
-
The error-free component of the RAD6/RAD18 DNA damage tolerance pathway of budding yeast employs sister-strand recombination
-
PMID:16247017
-
Zhang H, Lawrence CW. The error-free component of the RAD6/RAD18 DNA damage tolerance pathway of budding yeast employs sister-strand recombination. Proc Natl Acad Sci USA 2005; 102:15954-9; PMID:16247017; http://dx.doi.org/10. 1073/pnas.0504586102.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15954-15959
-
-
Zhang, H.1
Lawrence, C.W.2
-
88
-
-
0032169004
-
The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein family
-
PMID:9705497
-
Xiao W, Lin SL, Broomfield S, Chow BL, Wei YF. The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein family. Nucleic Acids Res 1998; 26:3908-14; PMID:9705497; http:// dx.doi.org/10.1093/nar/26.17.3908.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3908-3914
-
-
Xiao, W.1
Lin, S.L.2
Broomfield, S.3
Chow, B.L.4
Wei, Y.F.5
-
89
-
-
0028271574
-
Bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog
-
PMID:8182464
-
Oh CE, McMahon R, Benzer S, Tanouye MA. bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog. J Neurosci 1994; 14:3166-79; PMID:8182464.
-
(1994)
J Neurosci
, vol.14
, pp. 3166-3179
-
-
Oh, C.E.1
McMahon, R.2
Benzer, S.3
Tanouye, M.A.4
-
90
-
-
33845310025
-
Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination
-
PMID:17130289
-
Motegi A, Sood R, Moinova H, Markowitz SD, Liu PP, Myung K. Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination. J Cell Biol 2006; 175:703-8; PMID:17130289; http://dx.doi.org/10.1083/jcb.200606145.
-
(2006)
J Cell Biol
, vol.175
, pp. 703-708
-
-
Motegi, A.1
Sood, R.2
Moinova, H.3
Markowitz, S.D.4
Liu, P.P.5
Myung, K.6
-
91
-
-
33750309123
-
Role for RAD18 in homologous recombination in DT40 cells
-
PMID:16923963
-
Szüts D, Simpson LJ, Kabani S, Yamazoe M, Sale JE. Role for RAD18 in homologous recombination in DT40 cells. Mol Cell Biol 2006; 26:8032-41; PMID:16923963; http://dx.doi.org/10.1128/MCB.01291-06.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8032-8041
-
-
Szüts, D.1
Simpson, L.J.2
Kabani, S.3
Yamazoe, M.4
Sale, J.E.5
-
92
-
-
33749510488
-
RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40
-
PMID:16888649
-
Simpson LJ, Ross AL, Szüts D, Alviani CA, Oestergaard VH, Patel KJ, et al. RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40. EMBO Rep 2006; 7:927-32; PMID:16888649; http://dx.doi.org/10.1038/sj.embor.7400777.
-
(2006)
EMBO Rep
, vol.7
, pp. 927-932
-
-
Simpson, L.J.1
Ross, A.L.2
Szüts, D.3
Alviani, C.A.4
Oestergaard, V.H.5
Patel, K.J.6
-
93
-
-
0037107370
-
RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells
-
PMID:12374756
-
Yamashita YM, Okada T, Matsusaka T, Sonoda E, Zhao GY, Araki K, et al. RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells. EMBO J 2002; 21:5558-66; PMID:12374756; http://dx.doi.org/10. 1093/emboj/cdf534.
-
(2002)
EMBO J
, vol.21
, pp. 5558-5566
-
-
Yamashita, Y.M.1
Okada, T.2
Matsusaka, T.3
Sonoda, E.4
Zhao, G.Y.5
Araki, K.6
-
94
-
-
0030878003
-
The RAD5 gene product is involved in the avoidance of non-homologous end-joining of DNA double-strand breaks in the yeast Saccharomyces cerevisiae
-
PMID:9016623
-
Ahne F, Jha B, Eckardt-Schupp F. The RAD5 gene product is involved in the avoidance of non-homologous end-joining of DNA double-strand breaks in the yeast Saccharomyces cerevisiae. Nucleic Acids Res 1997; 25:743-9; PMID:9016623; http://dx.doi.org/10.1093/nar/25.4.743.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 743-749
-
-
Ahne, F.1
Jha, B.2
Eckardt-Schupp, F.3
-
95
-
-
53149134255
-
Regulation of double-stranded DNA gap repair by the RAD6 pathway
-
(Amst) PMID:18722556
-
Moertl S, Karras GI, Wismüller T, Ahne F, Eckardt- Schupp F. Regulation of double-stranded DNA gap repair by the RAD6 pathway. DNA Repair (Amst) 2008; 7:1893-906; PMID:18722556; http://dx.doi.org/10.1016/j.dnarep.2008. 07.016.
-
(2008)
DNA Repair
, vol.7
, pp. 1893-1906
-
-
Moertl, S.1
Karras, G.I.2
Wismüller, T.3
Ahne, F.4
Eckardt- Schupp, F.5
-
96
-
-
80051713813
-
Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double-strand breaks
-
PMID:21858012
-
Inagaki A, Sleddens-Linkels E, van Cappellen WA, Hibbert RG, Sixma TK, Hoeijmakers JH, et al. Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double-strand breaks. PLoS One 2011; 6:23155; PMID:21858012; http://dx.doi.org/10.1371/journal.pone. 0023155.
-
(2011)
PLoS One
, vol.6
, pp. 23155
-
-
Inagaki, A.1
Sleddens-Linkels, E.2
Van Cappellen, W.A.3
Hibbert, R.G.4
Sixma, T.K.5
Hoeijmakers, J.H.6
-
97
-
-
77957799898
-
Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway
-
PMID:20675655
-
Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM, Vaziri C. Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. J Biol Chem 2010; 285:31525-36; PMID:20675655; http://dx.doi.org/10.1074/jbc.M110.138206.
-
(2010)
J Biol Chem
, vol.285
, pp. 31525-31536
-
-
Song, I.Y.1
Palle, K.2
Gurkar, A.3
Tateishi, S.4
Kupfer, G.M.5
Vaziri, C.6
-
98
-
-
77958499239
-
RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network
-
PMID:20937699
-
Geng L, Huntoon CJ, Karnitz LM. RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network. J Cell Biol 2010; 191:249-57; PMID:20937699; http://dx.doi.org/10.1083/jcb.201005101.
-
(2010)
J Cell Biol
, vol.191
, pp. 249-257
-
-
Geng, L.1
Huntoon, C.J.2
Karnitz, L.M.3
-
99
-
-
55849091416
-
Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells
-
PMID:18845679
-
Niimi A, Brown S, Sabbioneda S, Kannouche PL, Scott A, Yasui A, et al. Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. Proc Natl Acad Sci USA 2008; 105:16125-30; PMID:18845679; http://dx.doi.org/10.1073/pnas.0802727105.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16125-16130
-
-
Niimi, A.1
Brown, S.2
Sabbioneda, S.3
Kannouche, P.L.4
Scott, A.5
Yasui, A.6
-
100
-
-
79956007456
-
Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition
-
PMID:21478670
-
Palle K, Vaziri C. Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition. Cell Cycle 2011; 10:1625-38; PMID:21478670; http://dx.doi.org/10. 4161/cc.10.10.15617.
-
(2011)
Cell Cycle
, vol.10
, pp. 1625-1638
-
-
Palle, K.1
Vaziri, C.2
-
101
-
-
15044351968
-
Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland
-
PMID:15767672
-
Lazzerini Denchi E, Attwooll C, Pasini D, Helin K. Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland. Mol Cell Biol 2005; 25:2660-72; PMID:15767672; http://dx.doi.org/10. 1128/MCB.25.7.2660-72.2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2660-2672
-
-
Lazzerini Denchi, E.1
Attwooll, C.2
Pasini, D.3
Helin, K.4
-
102
-
-
72949103076
-
E2F1 represses beta-catenin/ TCF activity by direct upregulation of Siah1
-
PMID:20187294
-
Xie W, Jin L, Mei Y, Wu M. E2F1 represses beta-catenin/ TCF activity by direct upregulation of Siah1. J Cell Mol Med 2009; 13:1719-27; PMID:20187294; http://dx.doi.org/10.1111/j.1582-4934.2008.00423.x.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 1719-1727
-
-
Xie, W.1
Jin, L.2
Mei, Y.3
Wu, M.4
-
103
-
-
79958288924
-
p53 governs telomere regulation feedback too, via TRF2
-
(Albany NY) PMID:21266744
-
Horikawa I, Fujita K, Harris CC. p53 governs telomere regulation feedback too, via TRF2. Aging (Albany NY) 2011; 3:26-32; PMID:21266744.
-
(2011)
Aging
, vol.3
, pp. 26-32
-
-
Horikawa, I.1
Fujita, K.2
Harris, C.C.3
-
104
-
-
31144459985
-
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
-
PMID:16273092
-
Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 2006; 439:353-7; PMID:16273092; http://dx.doi.org/10.1038/nature04296.
-
(2006)
Nature
, vol.439
, pp. 353-357
-
-
Bild, A.H.1
Yao, G.2
Chang, J.T.3
Wang, Q.4
Potti, A.5
Chasse, D.6
-
105
-
-
48949119363
-
Evaluation of biological pathways involved in chemotherapy response in breast cancer
-
PMID:18445275
-
Tordai A, Wang J, Andre F, Liedtke C, Yan K, Sotiriou C, et al. Evaluation of biological pathways involved in chemotherapy response in breast cancer. Breast Cancer Res 2008; 10:37; PMID:18445275; http://dx.doi.org/10.1186/ bcr2088.
-
(2008)
Breast Cancer Res
, vol.10
, pp. 37
-
-
Tordai, A.1
Wang, J.2
Andre, F.3
Liedtke, C.4
Yan, K.5
Sotiriou, C.6
-
106
-
-
77954929373
-
Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM
-
PMID:20534551
-
Wiedemeyer WR, Dunn IF, Quayle SN, Zhang J, Chheda MG, Dunn GP, et al. Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM. Proc Natl Acad Sci USA 2010; 107:11501-6; PMID:20534551; http://dx.doi.org/10.1073/pnas.1001613107.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11501-11506
-
-
Wiedemeyer, W.R.1
Dunn, I.F.2
Quayle, S.N.3
Zhang, J.4
Chheda, M.G.5
Dunn, G.P.6
|