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Volumn 11, Issue 6, 2012, Pages 1131-1141

Rad18 is a transcriptional target of E2F3

Author keywords

Cancer; Cell cycle; DNA damage; E2F3; Ubiquitin ligase

Indexed keywords

CYCLINE; HISTONE H2AX; RAD18 PROTEIN; TRANSCRIPTION FACTOR E2F3; UBIQUITIN PROTEIN LIGASE;

EID: 84858731339     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.11.6.19558     Document Type: Article
Times cited : (9)

References (106)
  • 1
    • 0026526437 scopus 로고
    • E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
    • PMID:1411535
    • Nevins JR. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 1992; 258:424-9; PMID:1411535; http://dx.doi.org/10.1126/ science.1411535.
    • (1992) Science , vol.258 , pp. 424-429
    • Nevins, J.R.1
  • 2
    • 0027382336 scopus 로고
    • Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein
    • PMID:8413249
    • Helin K, Harlow E, Fattaey A. Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. Mol Cell Biol 1993; 13:6501-8; PMID:8413249.
    • (1993) Mol Cell Biol , vol.13 , pp. 6501-6508
    • Helin, K.1    Harlow, E.2    Fattaey, A.3
  • 3
    • 0027140404 scopus 로고
    • Cell cycle-specific association of E2F with the p130 E1A-binding protein
    • PMID:8253385
    • Cobrinik D, Whyte P, Peeper DS, Jacks T, Weinberg RA. Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes Dev 1993; 7:2392-404; PMID:8253385; http://dx.doi.org/10.1101/gad.7.12a.2392.
    • (1993) Genes Dev , vol.7 , pp. 2392-2404
    • Cobrinik, D.1    Whyte, P.2    Peeper, D.S.3    Jacks, T.4    Weinberg, R.A.5
  • 4
    • 0026530730 scopus 로고
    • The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner
    • PMID:1531040
    • Shirodkar S, Ewen M, DeCaprio JA, Morgan J, Livingston DM, Chittenden T. The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell 1992; 68:157-66; PMID:1531040; http:// dx.doi.org/10.1016/0092-8674(92)90214-W.
    • (1992) Cell , vol.68 , pp. 157-166
    • Shirodkar, S.1    Ewen, M.2    DeCaprio, J.A.3    Morgan, J.4    Livingston, D.M.5    Chittenden, T.6
  • 5
    • 0026536876 scopus 로고
    • cdk2 is a component of the E2F-cyclin A complex
    • PMID:1310073
    • cdk2 is a component of the E2F-cyclin A complex. Cell 1992; 68:167-76; PMID:1310073; http://dx.doi.org/10.1016/0092-8674(92)90215-X.
    • (1992) Cell , vol.68 , pp. 167-176
    • Devoto, S.H.1    Mudryj, M.2    Pines, J.3    Hunter, T.4    Nevins, J.R.5
  • 6
    • 0026609875 scopus 로고
    • Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F
    • PMID:1530885
    • Cao L, Faha B, Dembski M, Tsai LH, Harlow E, Dyson N. Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature 1992; 355:176-9; PMID:1530885; http://dx.doi.org/10.1038/355176a0.
    • (1992) Nature , vol.355 , pp. 176-179
    • Cao, L.1    Faha, B.2    Dembski, M.3    Tsai, L.H.4    Harlow, E.5    Dyson, N.6
  • 7
    • 0025734783 scopus 로고
    • The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
    • PMID:1828394
    • Chittenden T, Livingston DM, Kaelin WG Jr. The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell 1991; 65:1073-82; PMID:1828394; http://dx.doi.org/10. 1016/0092-8674(91)90559-H.
    • (1991) Cell , vol.65 , pp. 1073-1082
    • Chittenden, T.1    Livingston, D.M.2    Kaelin Jr., W.G.3
  • 8
    • 0025905183 scopus 로고
    • The E2F transcription factor is a cellular target for the RB protein
    • PMID:1828392
    • Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR. The E2F transcription factor is a cellular target for the RB protein. Cell 1991; 65:1053-61; PMID:1828392; http://dx.doi.org/10.1016/0092-8674(91)90557-F.
    • (1991) Cell , vol.65 , pp. 1053-1061
    • Chellappan, S.P.1    Hiebert, S.2    Mudryj, M.3    Horowitz, J.M.4    Nevins, J.R.5
  • 9
    • 0025869428 scopus 로고
    • Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor
    • PMID:1710781
    • Bandara LR, La Thangue NB. Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature 1991; 351:494-7; PMID:1710781; http://dx.doi.org/10.1038/351494a0.
    • (1991) Nature , vol.351 , pp. 494-497
    • Bandara, L.R.1    La Thangue, N.B.2
  • 10
    • 0025910802 scopus 로고
    • The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F
    • PMID:1828393
    • Bagchi S, Weinmann R, Raychaudhuri P. The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F. Cell 1991; 65:1063-72; PMID:1828393; http://dx.doi.org/10.1016/0092- 8674(91)90558-G.
    • (1991) Cell , vol.65 , pp. 1063-1072
    • Bagchi, S.1    Weinmann, R.2    Raychaudhuri, P.3
  • 11
    • 0025893161 scopus 로고
    • Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A
    • PMID:1829647
    • Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR. Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell 1991; 65:1243-53; PMID:1829647; http://dx.doi.org/10.1016/0092-8674(91) 90019-U.
    • (1991) Cell , vol.65 , pp. 1243-1253
    • Mudryj, M.1    Devoto, S.H.2    Hiebert, S.W.3    Hunter, T.4    Pines, J.5    Nevins, J.R.6
  • 12
    • 0027299921 scopus 로고
    • Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F
    • PMID:8321204
    • Chittenden T, Livingston DM, DeCaprio JA. Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F. Mol Cell Biol 1993; 13:3975-83; PMID:8321204.
    • (1993) Mol Cell Biol , vol.13 , pp. 3975-3983
    • Chittenden, T.1    Livingston, D.M.2    DeCaprio, J.A.3
  • 13
  • 14
    • 0027769885 scopus 로고
    • Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members
    • PMID:8248803
    • Krek W, Livingston DM, Shirodkar S. Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science 1993; 262:1557-60; PMID:8248803; http://dx.doi.org/10.1126/science. 8248803.
    • (1993) Science , vol.262 , pp. 1557-1560
    • Krek, W.1    Livingston, D.M.2    Shirodkar, S.3
  • 15
    • 0027426917 scopus 로고
    • Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation
    • PMID:8405995
    • Helin K, Wu CL, Fattaey AR, Lees JA, Dynlacht BD, Ngwu C, et al. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev 1993; 7:1850-61; PMID:8405995; http://dx.doi.org/10.1101/gad.7.10.1850.
    • (1993) Genes Dev , vol.7 , pp. 1850-1861
    • Helin, K.1    Wu, C.L.2    Fattaey, A.R.3    Lees, J.A.4    Dynlacht, B.D.5    Ngwu, C.6
  • 16
    • 0027434084 scopus 로고
    • Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F
    • PMID:8223441
    • Bandara LR, Buck VM, Zamanian M, Johnston LH, La Thangue NB. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J 1993; 12:4317-24; PMID:8223441.
    • (1993) EMBO J , vol.12 , pp. 4317-4324
    • Bandara, L.R.1    Buck, V.M.2    Zamanian, M.3    Johnston, L.H.4    La Thangue, N.B.5
  • 17
    • 0027440919 scopus 로고
    • A new component of the transcription factor DRTF1/E2F
    • PMID:8413592
    • Girling R, Partridge JF, Bandara LR, Burden N, Totty NF, Hsuan JJ, et al. A new component of the transcription factor DRTF1/E2F. Nature 1993; 365:468; PMID:8413592; http://dx.doi.org/10.1038/365468d0.
    • (1993) Nature , vol.365 , pp. 468
    • Girling, R.1    Partridge, J.F.2    Bandara, L.R.3    Burden, N.4    Totty, N.F.5    Hsuan, J.J.6
  • 18
    • 50149120366 scopus 로고    scopus 로고
    • Cellular mechanisms of tumour suppression by the retinoblastoma gene
    • PMID:18650841
    • Burkhart DL, Sage J. Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat Rev Cancer 2008; 8:671-82; PMID:18650841; http:// dx.doi.org/10.1038/nrc2399.
    • (2008) Nat Rev Cancer , vol.8 , pp. 671-682
    • Burkhart, D.L.1    Sage, J.2
  • 19
    • 0039227088 scopus 로고    scopus 로고
    • Induction of S-phase entry by E2F transcription factors depends on their nuclear localization
    • PMID:9271426
    • Müller H, Moroni MC, Vigo E, Petersen BO, Bartek J, Helin K. Induction of S-phase entry by E2F transcription factors depends on their nuclear localization. Mol Cell Biol 1997; 17:5508-20; PMID:9271426.
    • (1997) Mol Cell Biol , vol.17 , pp. 5508-5520
    • Müller, H.1    Moroni, M.C.2    Vigo, E.3    Petersen, B.O.4    Bartek, J.5    Helin, K.6
  • 20
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • PMID:15864276
    • Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005; 5:341-54; PMID:15864276; http://dx.doi.org/10. 1038/nrc1609.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 21
    • 0035256698 scopus 로고    scopus 로고
    • Untangling the ErbB signalling network
    • PMID:11252954
    • Yarden Y, Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2001; 2:127-37; PMID:11252954; http://dx.doi.org/10.1038/35052073.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 127-137
    • Yarden, Y.1    Sliwkowski, M.X.2
  • 22
    • 60749109846 scopus 로고    scopus 로고
    • Cell cycle, CDKs and cancer: A changing paradigm
    • PMID:19238148
    • Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 2009; 9:153-66; PMID:19238148; http://dx.doi.org/10. 1038/nrc2602.
    • (2009) Nat Rev Cancer , vol.9 , pp. 153-166
    • Malumbres, M.1    Barbacid, M.2
  • 23
    • 27544470656 scopus 로고    scopus 로고
    • Mammalian cyclin-dependent kinases
    • PMID:16236519
    • Malumbres M, Barbacid M. Mammalian cyclin-dependent kinases. Trends Biochem Sci 2005; 30:630-41; PMID:16236519; http://dx.doi.org/10.1016/j.tibs. 2005.09.005.
    • (2005) Trends Biochem Sci , vol.30 , pp. 630-641
    • Malumbres, M.1    Barbacid, M.2
  • 24
    • 0035754080 scopus 로고    scopus 로고
    • To cycle or not to cycle: A critical decision in cancer
    • PMID:11902577
    • Malumbres M, Barbacid M. To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer 2001; 1:222-31; PMID:11902577; http://dx.doi.org/10. 1038/35106065.
    • (2001) Nat Rev Cancer , vol.1 , pp. 222-231
    • Malumbres, M.1    Barbacid, M.2
  • 25
    • 0034306996 scopus 로고    scopus 로고
    • The Rb/E2F pathway: Expanding roles and emerging paradigms
    • PMID:11018009
    • Harbour JW, Dean DC. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev 2000; 14:2393-409; PMID:11018009; http://dx.doi.org/10. 1101/gad.813200.
    • (2000) Genes Dev , vol.14 , pp. 2393-2409
    • Harbour, J.W.1    Dean, D.C.2
  • 26
    • 0035063183 scopus 로고    scopus 로고
    • The Rb/E2F pathway and cancer
    • PMID:11257102
    • Nevins JR. The Rb/E2F pathway and cancer. Hum Mol Genet 2001; 10:699-703; PMID:11257102; http:// dx.doi.org/10.1093/hmg/10.7.699.
    • (2001) Hum Mol Genet , vol.10 , pp. 699-703
    • Nevins, J.R.1
  • 27
    • 1542426648 scopus 로고    scopus 로고
    • Amplification and overexpression of E2F3 in human bladder cancer
    • PMID:14716298
    • Feber A, Clark J, Goodwin G, Dodson AR, Smith PH, Fletcher A, et al. Amplification and overexpression of E2F3 in human bladder cancer. Oncogene 2004; 23:1627-30; PMID:14716298; http://dx.doi.org/10.1038/sj.onc.1207274.
    • (2004) Oncogene , vol.23 , pp. 1627-1630
    • Feber, A.1    Clark, J.2    Goodwin, G.3    Dodson, A.R.4    Smith, P.H.5    Fletcher, A.6
  • 28
    • 42549109141 scopus 로고    scopus 로고
    • Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification
    • PMID:18037967
    • Hurst CD, Tomlinson DC, Williams SV, Platt FM, Knowles MA. Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification. Oncogene 2008; 27:2716-27; PMID:18037967; http://dx.doi.org/10.1038/sj.onc.1210934.
    • (2008) Oncogene , vol.27 , pp. 2716-2727
    • Hurst, C.D.1    Tomlinson, D.C.2    Williams, S.V.3    Platt, F.M.4    Knowles, M.A.5
  • 29
    • 27144521756 scopus 로고    scopus 로고
    • Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma
    • PMID:16007192
    • Grasemann C, Gratias S, Stephan H, Schüler A, Schramm A, Klein-Hitpass L, et al. Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma. Oncogene 2005; 24:6441-9; PMID:16007192.
    • (2005) Oncogene , vol.24 , pp. 6441-6449
    • Grasemann, C.1    Gratias, S.2    Stephan, H.3    Schüler, A.4    Schramm, A.5    Klein-Hitpass, L.6
  • 30
    • 33644881673 scopus 로고    scopus 로고
    • Expression analysis of 6p22 genomic gain in retinoblastoma
    • PMID:16180235
    • Orlic M, Spencer CE, Wang L, Gallie BL. Expression analysis of 6p22 genomic gain in retinoblastoma. Genes Chromosomes Cancer 2006; 45:72-82; PMID:16180235; http://dx.doi.org/10.1002/gcc.20263.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 72-82
    • Orlic, M.1    Spencer, C.E.2    Wang, L.3    Gallie, B.L.4
  • 31
    • 33750900241 scopus 로고    scopus 로고
    • Retinoblastoma regulatory pathway in lung cancer
    • PMID:17100603
    • Wikenheiser-Brokamp KA. Retinoblastoma regulatory pathway in lung cancer. Curr Mol Med 2006; 6:783-93; PMID:17100603.
    • (2006) Curr Mol Med , vol.6 , pp. 783-793
    • Wikenheiser-Brokamp, K.A.1
  • 32
    • 0034425049 scopus 로고    scopus 로고
    • Loss-of- Heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays
    • PMID:10973224
    • Lindblad-Toh K, Tanenbaum DM, Daly MJ, Winchester E, Lui WO, Villapakkam A, et al. Loss-of- heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays. Nat Biotechnol 2000; 18:1001-5; PMID:10973224; http:// dx.doi.org/10.1038/79269.
    • (2000) Nat Biotechnol , vol.18 , pp. 1001-1005
    • Lindblad-Toh, K.1    Tanenbaum, D.M.2    Daly, M.J.3    Winchester, E.4    Lui, W.O.5    Villapakkam, A.6
  • 33
    • 33751120208 scopus 로고    scopus 로고
    • Nuclear overexpression of the E2F3 transcription factor in human lung cancer
    • PMID:16938365
    • Cooper CS, Nicholson AG, Foster C, Dodson A, Edwards S, Fletcher A, et al. Nuclear overexpression of the E2F3 transcription factor in human lung cancer. Lung Cancer 2006; 54:155-62; PMID:16938365; http://dx.doi.org/10.1016/j. lungcan.2006.07.005.
    • (2006) Lung Cancer , vol.54 , pp. 155-162
    • Cooper, C.S.1    Nicholson, A.G.2    Foster, C.3    Dodson, A.4    Edwards, S.5    Fletcher, A.6
  • 34
    • 33746610140 scopus 로고    scopus 로고
    • Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF
    • PMID:16835303
    • Qin G, Kishore R, Dolan CM, Silver M, Wecker A, Luedemann CN, et al. Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF. Proc Natl Acad Sci USA 2006; 103:11015-20; PMID:16835303; http://dx.doi.org/10.1073/pnas.0509533103.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11015-11020
    • Qin, G.1    Kishore, R.2    Dolan, C.M.3    Silver, M.4    Wecker, A.5    Luedemann, C.N.6
  • 35
    • 50649086353 scopus 로고    scopus 로고
    • Mouse development with a single E2F activator
    • PMID:18594513
    • Tsai SY, Opavsky R, Sharma N, Wu L, Naidu S, Nolan E, et al. Mouse development with a single E2F activator. Nature 2008; 454:1137-41; PMID:18594513; http://dx.doi.org/10.1038/nature07066.
    • (2008) Nature , vol.454 , pp. 1137-1141
    • Tsai, S.Y.1    Opavsky, R.2    Sharma, N.3    Wu, L.4    Naidu, S.5    Nolan, E.6
  • 37
    • 0035265833 scopus 로고    scopus 로고
    • dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development
    • PMID:11463372
    • Ceol CJ, Horvitz HR. dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Mol Cell 2001; 7:461-73; PMID:11463372; http://dx.doi.org/10.1016/S1097-2765(01)00194-0.
    • (2001) Mol Cell , vol.7 , pp. 461-473
    • Ceol, C.J.1    Horvitz, H.R.2
  • 38
    • 11244252136 scopus 로고    scopus 로고
    • Lin-35 Rb acts in the major hypodermis to oppose ras-mediated vulval induction in C. elegans
    • PMID:15621535
    • Myers TR, Greenwald I. lin-35 Rb acts in the major hypodermis to oppose ras-mediated vulval induction in C. elegans. Dev Cell 2005; 8:117-23; PMID:15621535; http://dx.doi.org/10.1016/j.devcel.2004.11.015.
    • (2005) Dev Cell , vol.8 , pp. 117-123
    • Myers, T.R.1    Greenwald, I.2
  • 39
    • 0032939925 scopus 로고    scopus 로고
    • Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
    • PMID:10207094
    • Blattner C, Sparks A, Lane D. Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol Cell Biol 1999; 19:3704-13; PMID:10207094.
    • (1999) Mol Cell Biol , vol.19 , pp. 3704-3713
    • Blattner, C.1    Sparks, A.2    Lane, D.3
  • 40
    • 73549095168 scopus 로고    scopus 로고
    • E2F3 is a mediator of DNA damage- Induced apoptosis
    • PMID:19917728
    • Martinez LA, Goluszko E, Chen HZ, Leone G, Post S, Lozano G, et al. E2F3 is a mediator of DNA damage- induced apoptosis. Mol Cell Biol 2010; 30:524-36; PMID:19917728; http://dx.doi.org/10.1128/MCB.00938-09.
    • (2010) Mol Cell Biol , vol.30 , pp. 524-536
    • Martinez, L.A.1    Goluszko, E.2    Chen, H.Z.3    Leone, G.4    Post, S.5    Lozano, G.6
  • 41
    • 34247199852 scopus 로고    scopus 로고
    • Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage
    • PMID:17380128
    • Inoue Y, Kitagawa M, Taya Y. Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage. EMBO J 2007; 26:2083-93; PMID:17380128; http://dx.doi.org/10.1038/sj.emboj.7601652.
    • (2007) EMBO J , vol.26 , pp. 2083-2093
    • Inoue, Y.1    Kitagawa, M.2    Taya, Y.3
  • 42
    • 0026769912 scopus 로고
    • Transcriptional repression of the E2-containing promoters EIIaE, c-myc and RB1 by the product of the RB1 gene
    • PMID:1385853
    • Hamel PA, Gill RM, Phillips RA, Gallie BL. Transcriptional repression of the E2-containing promoters EIIaE, c-myc and RB1 by the product of the RB1 gene. Mol Cell Biol 1992; 12:3431-8; PMID:1385853.
    • (1992) Mol Cell Biol , vol.12 , pp. 3431-3438
    • Hamel, P.A.1    Gill, R.M.2    Phillips, R.A.3    Gallie, B.L.4
  • 43
    • 0026636908 scopus 로고
    • Retinoblastoma protein switches the E2F site from positive to negative element
    • PMID:1321348
    • Weintraub SJ, Prater CA, Dean DC. Retinoblastoma protein switches the E2F site from positive to negative element. Nature 1992; 358:259-61; PMID:1321348; http://dx.doi.org/10.1038/358259a0.
    • (1992) Nature , vol.358 , pp. 259-261
    • Weintraub, S.J.1    Prater, C.A.2    Dean, D.C.3
  • 44
    • 0028960617 scopus 로고
    • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
    • PMID:7884898
    • Kowalik TF, DeGregori J, Schwarz JK, Nevins JR. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J Virol 1995; 69:2491-500; PMID:7884898.
    • (1995) J Virol , vol.69 , pp. 2491-2500
    • Kowalik, T.F.1    DeGregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 45
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • PMID:8170954
    • Wu X, Levine AJ. p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci USA 1994; 91:3602-6; PMID:8170954; http://dx.doi.org/10.1073/pnas.91.9. 3602.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 46
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • PMID:7971984
    • Qin XQ, Livingston DM, Kaelin WG Jr, Adams PD. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci USA 1994; 91:10918-22; PMID:7971984; http://dx.doi.org/10.1073/ pnas.91.23.10918.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10918-10922
    • Qin, X.Q.1    Livingston, D.M.2    Kaelin Jr., W.G.3    Adams, P.D.4
  • 47
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • PMID:7969153
    • Shan B, Lee WH. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol Cell Biol 1994; 14:8166-73; PMID:7969153.
    • (1994) Mol Cell Biol , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.H.2
  • 48
    • 0031992159 scopus 로고    scopus 로고
    • E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2
    • PMID:9486847
    • Kowalik TF, DeGregori J, Leone G, Jakoi L, Nevins JR. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ 1998; 9:113-8; PMID:9486847.
    • (1998) Cell Growth Differ , vol.9 , pp. 113-118
    • Kowalik, T.F.1    DeGregori, J.2    Leone, G.3    Jakoi, L.4    Nevins, J.R.5
  • 49
    • 0030739355 scopus 로고    scopus 로고
    • Induction of DNA synthesis and apoptosis are separable functions of E2F-1
    • PMID:9242492
    • Phillips AC, Bates S, Ryan KM, Helin K, Vousden KH. Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev 1997; 11:1853-63; PMID:9242492; http://dx.doi.org/10.1101/gad.11.14.1853.
    • (1997) Genes Dev , vol.11 , pp. 1853-1863
    • Phillips, A.C.1    Bates, S.2    Ryan, K.M.3    Helin, K.4    Vousden, K.H.5
  • 50
    • 0032622050 scopus 로고    scopus 로고
    • p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin
    • PMID:9863003
    • Meng RD, Phillips P, El-Deiry WS. p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin. Int J Oncol 1999; 14:5-14; PMID:9863003.
    • (1999) Int J Oncol , vol.14 , pp. 5-14
    • Meng, R.D.1    Phillips, P.2    El-Deiry, W.S.3
  • 51
    • 0345299171 scopus 로고    scopus 로고
    • Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation
    • PMID:9862970
    • Höfferer M, Wirbelauer C, Humar B, Krek W. Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation. Nucleic Acids Res 1999; 27:491-5; PMID:9862970; http://dx.doi.org/10.1093/nar/27.2.491.
    • (1999) Nucleic Acids Res , vol.27 , pp. 491-495
    • Höfferer, M.1    Wirbelauer, C.2    Humar, B.3    Krek, W.4
  • 52
    • 10644270921 scopus 로고    scopus 로고
    • p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
    • PMID:15601819
    • Urist M, Tanaka T, Poyurovsky MV, Prives C. p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes Dev 2004; 18:3041-54; PMID:15601819; http://dx.doi.org/10.1101/gad.1221004.
    • (2004) Genes Dev , vol.18 , pp. 3041-3054
    • Urist, M.1    Tanaka, T.2    Poyurovsky, M.V.3    Prives, C.4
  • 53
    • 0038752083 scopus 로고    scopus 로고
    • Chk2 activates E2F-1 in response to DNA damage
    • PMID:12717439
    • Stevens C, Smith L, La Thangue NB. Chk2 activates E2F-1 in response to DNA damage. Nat Cell Biol 2003; 5:401-9; PMID:12717439; http://dx.doi.org/10. 1038/ncb974.
    • (2003) Nat Cell Biol , vol.5 , pp. 401-409
    • Stevens, C.1    Smith, L.2    La Thangue, N.B.3
  • 54
    • 0035878122 scopus 로고    scopus 로고
    • Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
    • PMID:11459832
    • Lin WC, Lin FT, Nevins JR. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev 2001; 15:1833-44; PMID:11459832.
    • (2001) Genes Dev , vol.15 , pp. 1833-1844
    • Lin, W.C.1    Lin, F.T.2    Nevins, J.R.3
  • 55
    • 0030828886 scopus 로고    scopus 로고
    • Role for E2F in DNA damage-induced entry of cells into S phase
    • PMID:9288762
    • Huang Y, Ishiko T, Nakada S, Utsugisawa T, Kato T, Yuan ZM. Role for E2F in DNA damage-induced entry of cells into S phase. Cancer Res 1997; 57:3640-3; PMID:9288762.
    • (1997) Cancer Res , vol.57 , pp. 3640-3643
    • Huang, Y.1    Ishiko, T.2    Nakada, S.3    Utsugisawa, T.4    Kato, T.5    Yuan, Z.M.6
  • 56
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • PMID:19033363
    • Huang W, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 2009; 37:1-13; PMID:19033363; http://dx.doi.org/10.1093/nar/gkn923.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 57
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • PMID:19131956
    • Huang W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009; 4:44-57; PMID:19131956; http://dx.doi.org/10.1038/nprot.2008.211.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 58
    • 36249031962 scopus 로고    scopus 로고
    • RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
    • PMID:18001825
    • Huen MS, Grant R, Manke I, Minn K, Yu X, Yaffe MB, et al. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 2007; 131:901-14; PMID:18001825; http://dx.doi.org/10.1016/j. cell.2007.09.041.
    • (2007) Cell , vol.131 , pp. 901-914
    • Huen, M.S.1    Grant, R.2    Manke, I.3    Minn, K.4    Yu, X.5    Yaffe, M.B.6
  • 59
    • 0037068455 scopus 로고    scopus 로고
    • RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
    • PMID:12226657
    • Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 2002; 419:135-41; PMID:12226657; http:// dx.doi.org/10.1038/nature00991.
    • (2002) Nature , vol.419 , pp. 135-141
    • Hoege, C.1    Pfander, B.2    Moldovan, G.L.3    Pyrowolakis, G.4    Jentsch, S.5
  • 60
    • 80051748549 scopus 로고    scopus 로고
    • RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control
    • PMID:21855804
    • Bourgo RJ, Thangavel C, Ertel A, Bergseid J, McClendon AK, Wilkens L, et al. RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control. Mol Cell 2011; 43:663-72; PMID:21855804; http:// dx.doi.org/10.1016/j.molcel.2011.06.029.
    • (2011) Mol Cell , vol.43 , pp. 663-672
    • Bourgo, R.J.1    Thangavel, C.2    Ertel, A.3    Bergseid, J.4    McClendon, A.K.5    Wilkens, L.6
  • 61
    • 0019174693 scopus 로고
    • Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes
    • PMID:6249803
    • Wilkinson KD, Urban MK, Haas AL. Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes. J Biol Chem 1980; 255:7529-32; PMID:6249803.
    • (1980) J Biol Chem , vol.255 , pp. 7529-7532
    • Wilkinson, K.D.1    Urban, M.K.2    Haas, A.L.3
  • 62
    • 0019000271 scopus 로고
    • Proposed role of ATP in protein breakdown: Conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis
    • PMID:6990414
    • Hershko A, Ciechanover A, Heller H, Haas AL, Rose IA. Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis. Proc Natl Acad Sci USA 1980; 77:1783-6; PMID:6990414; http://dx.doi. org/10.1073/pnas.77.4.1783.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1783-1786
    • Hershko, A.1    Ciechanover, A.2    Heller, H.3    Haas, A.L.4    Rose, I.A.5
  • 63
    • 0018992813 scopus 로고
    • ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation
    • PMID:6769112
    • Ciechanover A, Heller H, Elias S, Haas AL, Hershko A. ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation. Proc Natl Acad Sci USA 1980; 77:1365-8; PMID:6769112; http://dx.doi.org/10.1073/pnas.77.3.1365.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1365-1368
    • Ciechanover, A.1    Heller, H.2    Elias, S.3    Haas, A.L.4    Hershko, A.5
  • 64
    • 0018772190 scopus 로고
    • Resolution of the ATP-dependent proteolytic system from reticulocytes: A component that interacts with ATP
    • PMID:290989
    • Hershko A, Ciechanover A, Rose IA. Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP. Proc Natl Acad Sci USA 1979; 76:3107-10; PMID:290989; http://dx.doi.org/10.1073/ pnas.76.7.3107.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 3107-3110
    • Hershko, A.1    Ciechanover, A.2    Rose, I.A.3
  • 65
    • 0342265782 scopus 로고
    • A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes
    • PMID:264694
    • Etlinger JD, Goldberg AL. A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes. Proc Natl Acad Sci USA 1977; 74:54-8; PMID:264694; http://dx.doi.org/10.1073/pnas.74.1. 54.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 54-58
    • Etlinger, J.D.1    Goldberg, A.L.2
  • 66
    • 77049143850 scopus 로고
    • The release of labeled amino acids from the proteins of rat liver slices
    • PMID:13044783
    • Simpson MV. The release of labeled amino acids from the proteins of rat liver slices. J Biol Chem 1953; 201:143-54; PMID:13044783.
    • (1953) J Biol Chem , vol.201 , pp. 143-154
    • Simpson, M.V.1
  • 67
    • 27144529182 scopus 로고    scopus 로고
    • Ubiquitylation and cell signaling
    • PMID:16148945
    • Haglund K, Dikic I. Ubiquitylation and cell signaling. EMBO J 2005; 24:3353-9; PMID:16148945; http:// dx.doi.org/10.1038/sj.emboj.7600808.
    • (2005) EMBO J , vol.24 , pp. 3353-3359
    • Haglund, K.1    Dikic, I.2
  • 68
    • 78649492271 scopus 로고    scopus 로고
    • The ubiquitous role of ubiquitin in the DNA damage response
    • (Amst) PMID:21056014
    • Al-Hakim A, Escribano-Diaz C, Landry MC, O'Donnell L, Panier S, Szilard RK, et al. The ubiquitous role of ubiquitin in the DNA damage response. DNA Repair (Amst) 2010; 9:1229-40; PMID:21056014; http://dx.doi.org/10.1016/j. dnarep.2010.09.011.
    • (2010) DNA Repair , vol.9 , pp. 1229-1240
    • Al-Hakim, A.1    Escribano-Diaz, C.2    Landry, M.C.3    O'Donnell, L.4    Panier, S.5    Szilard, R.K.6
  • 69
    • 36248966246 scopus 로고    scopus 로고
    • RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
    • PMID:18001824
    • Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, Lukas C, et al. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 2007; 131:887-900; PMID:18001824; http://dx.doi.org/10.1016/j.cell.2007.09.040.
    • (2007) Cell , vol.131 , pp. 887-900
    • Mailand, N.1    Bekker-Jensen, S.2    Faustrup, H.3    Melander, F.4    Bartek, J.5    Lukas, C.6
  • 70
    • 33646117239 scopus 로고    scopus 로고
    • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
    • PMID:16618811
    • Bekker-Jensen S, Lukas C, Kitagawa R, Melander F, Kastan MB, Bartek J, et al. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 2006; 173:195-206; PMID:16618811; http://dx.doi.org/10.1083/jcb.200510130.
    • (2006) J Cell Biol , vol.173 , pp. 195-206
    • Bekker-Jensen, S.1    Lukas, C.2    Kitagawa, R.3    Melander, F.4    Kastan, M.B.5    Bartek, J.6
  • 71
    • 67349168142 scopus 로고    scopus 로고
    • RAD18 transmits DNA damage signalling to elicit homologous recombination repair
    • PMID:19396164
    • Huang J, Huen MS, Kim H, Leung CC, Glover JN, Yu X, et al. RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol 2009; 11:592-603; PMID:19396164; http://dx.doi. org/10.1038/ncb1865.
    • (2009) Nat Cell Biol , vol.11 , pp. 592-603
    • Huang, J.1    Huen, M.S.2    Kim, H.3    Leung, C.C.4    Glover, J.N.5    Yu, X.6
  • 72
    • 79956053726 scopus 로고    scopus 로고
    • Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis
    • PMID:21247883
    • Lee BK, Bhinge AA, Iyer VR. Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis. Nucleic Acids Res 2011; 39:3558-73; PMID:21247883; http://dx.doi.org/10.1093/ nar/gkq1313.
    • (2011) Nucleic Acids Res , vol.39 , pp. 3558-3573
    • Lee, B.K.1    Bhinge, A.A.2    Iyer, V.R.3
  • 73
    • 77956997759 scopus 로고    scopus 로고
    • Damage-specific modification of PCNA
    • PMID:20930510
    • Das-Bradoo S, Nguyen HD, Bielinsky AK. Damage-specific modification of PCNA. Cell Cycle 2010; 9:3674-9; PMID:20930510; http://dx.doi.org/10.4161/cc.9. 18.13121.
    • (2010) Cell Cycle , vol.9 , pp. 3674-3679
    • Das-Bradoo, S.1    Nguyen, H.D.2    Bielinsky, A.K.3
  • 75
    • 2442417331 scopus 로고    scopus 로고
    • Interaction of human DNA polymerase eta with monoubiquitinated PCNA: A possible mechanism for the polymerase switch in response to DNA damage
    • PMID:15149598
    • Kannouche PL, Wing J, Lehmann AR. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell 2004; 14:491-500; PMID:15149598; http://dx.doi.org/10.1016/S1097-2765(04)00259-X.
    • (2004) Mol Cell , vol.14 , pp. 491-500
    • Kannouche, P.L.1    Wing, J.2    Lehmann, A.R.3
  • 76
    • 0141831006 scopus 로고    scopus 로고
    • Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation
    • PMID:12968183
    • Stelter P, Ulrich HD. Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature 2003; 425:188-91; PMID:12968183; http://dx.doi.org/10.1038/nature01965.
    • (2003) Nature , vol.425 , pp. 188-191
    • Stelter, P.1    Ulrich, H.D.2
  • 77
    • 28844506236 scopus 로고    scopus 로고
    • Suffering in silence: The tolerance of DNA damage
    • PMID:16341080
    • Friedberg EC. Suffering in silence: the tolerance of DNA damage. Nat Rev Mol Cell Biol 2005; 6:943-53; PMID:16341080; http://dx.doi.org/10.1038/nrm1781.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 943-953
    • Friedberg, E.C.1
  • 78
    • 18844415068 scopus 로고    scopus 로고
    • Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae
    • PMID:15687278
    • Minesinger BK, Jinks-Robertson S. Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae. Genetics 2005; 169:1939-55; PMID:15687278; http://dx.doi.org/10. 1534/genetics.104.033894.
    • (2005) Genetics , vol.169 , pp. 1939-1955
    • Minesinger, B.K.1    Jinks-Robertson, S.2
  • 79
    • 19444383801 scopus 로고    scopus 로고
    • Trading places: How do DNA polymerases switch during translesion DNA synthesis?
    • PMID:15916957
    • Friedberg EC, Lehmann AR, Fuchs RP. Trading places: how do DNA polymerases switch during translesion DNA synthesis? Mol Cell 2005; 18:499-505; PMID:15916957; http://dx.doi.org/10.1016/j.molcel. 2005.03.032.
    • (2005) Mol Cell , vol.18 , pp. 499-505
    • Friedberg, E.C.1    Lehmann, A.R.2    Fuchs, R.P.3
  • 80
    • 1942439667 scopus 로고    scopus 로고
    • Switching from highfidelity replicases to low-fidelity lesion-bypass polymerases
    • PMID:15196456
    • Plosky BS, Woodgate R. Switching from highfidelity replicases to low-fidelity lesion-bypass polymerases. Curr Opin Genet Dev 2004; 14:113-9; PMID:15196456; http://dx.doi.org/10.1016/j.gde.2004.02.002.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 113-119
    • Plosky, B.S.1    Woodgate, R.2
  • 81
    • 0942268173 scopus 로고    scopus 로고
    • Xeroderma pigmentosum variant and error-prone DNA polymerases
    • PMID:14726018
    • Kannouche P, Stary A. Xeroderma pigmentosum variant and error-prone DNA polymerases. Biochimie 2003; 85:1123-32; PMID:14726018; http://dx.doi.org/10. 1016/j.biochi.2003.10.009.
    • (2003) Biochimie , vol.85 , pp. 1123-1132
    • Kannouche, P.1    Stary, A.2
  • 82
    • 0035808417 scopus 로고    scopus 로고
    • Purification and characterization of polkappa, a DNA polymerase encoded by the human DINB1 gene
    • PMID:11024016
    • Gerlach VL, Feaver WJ, Fischhaber PL, Friedberg EC. Purification and characterization of polkappa, a DNA polymerase encoded by the human DINB1 gene. J Biol Chem 2001; 276:92-8; PMID:11024016; http:// dx.doi.org/10.1074/jbc. M004413200.
    • (2001) J Biol Chem , vol.276 , pp. 92-98
    • Gerlach, V.L.1    Feaver, W.J.2    Fischhaber, P.L.3    Friedberg, E.C.4
  • 83
    • 0035807870 scopus 로고    scopus 로고
    • Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA
    • PMID:11724965
    • Haracska L, Johnson RE, Unk I, Phillips BB, Hurwitz J, Prakash L, et al. Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA. Proc Natl Acad Sci USA 2001; 98:14256-61; PMID:11724965; http://dx.doi.org/10.1073/pnas.261560798.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14256-14261
    • Haracska, L.1    Johnson, R.E.2    Unk, I.3    Phillips, B.B.4    Hurwitz, J.5    Prakash, L.6
  • 84
    • 0034600851 scopus 로고    scopus 로고
    • Two RING finger proteins mediate cooperation between ubiquitin- conjugating enzymes in DNA repair
    • PMID:10880451
    • Ulrich HD, Jentsch S. Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J 2000; 19:3388-97; PMID:10880451; http://dx.doi.org/10.1093/emboj/19.13.3388.
    • (2000) EMBO J , vol.19 , pp. 3388-3397
    • Ulrich, H.D.1    Jentsch, S.2
  • 85
    • 57749169348 scopus 로고    scopus 로고
    • SUMOylation regulates Rad18-mediated template switch
    • PMID:19092928
    • Branzei D, Vanoli F, Foiani M. SUMOylation regulates Rad18-mediated template switch. Nature 2008; 456:915-20; PMID:19092928; http://dx.doi.org/10. 1038/nature07587.
    • (2008) Nature , vol.456 , pp. 915-920
    • Branzei, D.1    Vanoli, F.2    Foiani, M.3
  • 86
    • 0030814759 scopus 로고    scopus 로고
    • Involvement of the yeast DNA polymerase delta in DNA repair in vivo
    • PMID:9258670
    • Giot L, Chanet R, Simon M, Facca C, Faye G. Involvement of the yeast DNA polymerase delta in DNA repair in vivo. Genetics 1997; 146:1239-51; PMID:9258670.
    • (1997) Genetics , vol.146 , pp. 1239-1251
    • Giot, L.1    Chanet, R.2    Simon, M.3    Facca, C.4    Faye, G.5
  • 87
    • 27644590452 scopus 로고    scopus 로고
    • The error-free component of the RAD6/RAD18 DNA damage tolerance pathway of budding yeast employs sister-strand recombination
    • PMID:16247017
    • Zhang H, Lawrence CW. The error-free component of the RAD6/RAD18 DNA damage tolerance pathway of budding yeast employs sister-strand recombination. Proc Natl Acad Sci USA 2005; 102:15954-9; PMID:16247017; http://dx.doi.org/10. 1073/pnas.0504586102.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15954-15959
    • Zhang, H.1    Lawrence, C.W.2
  • 88
    • 0032169004 scopus 로고    scopus 로고
    • The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein family
    • PMID:9705497
    • Xiao W, Lin SL, Broomfield S, Chow BL, Wei YF. The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein family. Nucleic Acids Res 1998; 26:3908-14; PMID:9705497; http:// dx.doi.org/10.1093/nar/26.17.3908.
    • (1998) Nucleic Acids Res , vol.26 , pp. 3908-3914
    • Xiao, W.1    Lin, S.L.2    Broomfield, S.3    Chow, B.L.4    Wei, Y.F.5
  • 89
    • 0028271574 scopus 로고
    • Bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog
    • PMID:8182464
    • Oh CE, McMahon R, Benzer S, Tanouye MA. bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog. J Neurosci 1994; 14:3166-79; PMID:8182464.
    • (1994) J Neurosci , vol.14 , pp. 3166-3179
    • Oh, C.E.1    McMahon, R.2    Benzer, S.3    Tanouye, M.A.4
  • 90
    • 33845310025 scopus 로고    scopus 로고
    • Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination
    • PMID:17130289
    • Motegi A, Sood R, Moinova H, Markowitz SD, Liu PP, Myung K. Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination. J Cell Biol 2006; 175:703-8; PMID:17130289; http://dx.doi.org/10.1083/jcb.200606145.
    • (2006) J Cell Biol , vol.175 , pp. 703-708
    • Motegi, A.1    Sood, R.2    Moinova, H.3    Markowitz, S.D.4    Liu, P.P.5    Myung, K.6
  • 91
    • 33750309123 scopus 로고    scopus 로고
    • Role for RAD18 in homologous recombination in DT40 cells
    • PMID:16923963
    • Szüts D, Simpson LJ, Kabani S, Yamazoe M, Sale JE. Role for RAD18 in homologous recombination in DT40 cells. Mol Cell Biol 2006; 26:8032-41; PMID:16923963; http://dx.doi.org/10.1128/MCB.01291-06.
    • (2006) Mol Cell Biol , vol.26 , pp. 8032-8041
    • Szüts, D.1    Simpson, L.J.2    Kabani, S.3    Yamazoe, M.4    Sale, J.E.5
  • 92
    • 33749510488 scopus 로고    scopus 로고
    • RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40
    • PMID:16888649
    • Simpson LJ, Ross AL, Szüts D, Alviani CA, Oestergaard VH, Patel KJ, et al. RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40. EMBO Rep 2006; 7:927-32; PMID:16888649; http://dx.doi.org/10.1038/sj.embor.7400777.
    • (2006) EMBO Rep , vol.7 , pp. 927-932
    • Simpson, L.J.1    Ross, A.L.2    Szüts, D.3    Alviani, C.A.4    Oestergaard, V.H.5    Patel, K.J.6
  • 93
    • 0037107370 scopus 로고    scopus 로고
    • RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells
    • PMID:12374756
    • Yamashita YM, Okada T, Matsusaka T, Sonoda E, Zhao GY, Araki K, et al. RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells. EMBO J 2002; 21:5558-66; PMID:12374756; http://dx.doi.org/10. 1093/emboj/cdf534.
    • (2002) EMBO J , vol.21 , pp. 5558-5566
    • Yamashita, Y.M.1    Okada, T.2    Matsusaka, T.3    Sonoda, E.4    Zhao, G.Y.5    Araki, K.6
  • 94
    • 0030878003 scopus 로고    scopus 로고
    • The RAD5 gene product is involved in the avoidance of non-homologous end-joining of DNA double-strand breaks in the yeast Saccharomyces cerevisiae
    • PMID:9016623
    • Ahne F, Jha B, Eckardt-Schupp F. The RAD5 gene product is involved in the avoidance of non-homologous end-joining of DNA double-strand breaks in the yeast Saccharomyces cerevisiae. Nucleic Acids Res 1997; 25:743-9; PMID:9016623; http://dx.doi.org/10.1093/nar/25.4.743.
    • (1997) Nucleic Acids Res , vol.25 , pp. 743-749
    • Ahne, F.1    Jha, B.2    Eckardt-Schupp, F.3
  • 95
    • 53149134255 scopus 로고    scopus 로고
    • Regulation of double-stranded DNA gap repair by the RAD6 pathway
    • (Amst) PMID:18722556
    • Moertl S, Karras GI, Wismüller T, Ahne F, Eckardt- Schupp F. Regulation of double-stranded DNA gap repair by the RAD6 pathway. DNA Repair (Amst) 2008; 7:1893-906; PMID:18722556; http://dx.doi.org/10.1016/j.dnarep.2008. 07.016.
    • (2008) DNA Repair , vol.7 , pp. 1893-1906
    • Moertl, S.1    Karras, G.I.2    Wismüller, T.3    Ahne, F.4    Eckardt- Schupp, F.5
  • 96
    • 80051713813 scopus 로고    scopus 로고
    • Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double-strand breaks
    • PMID:21858012
    • Inagaki A, Sleddens-Linkels E, van Cappellen WA, Hibbert RG, Sixma TK, Hoeijmakers JH, et al. Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double-strand breaks. PLoS One 2011; 6:23155; PMID:21858012; http://dx.doi.org/10.1371/journal.pone. 0023155.
    • (2011) PLoS One , vol.6 , pp. 23155
    • Inagaki, A.1    Sleddens-Linkels, E.2    Van Cappellen, W.A.3    Hibbert, R.G.4    Sixma, T.K.5    Hoeijmakers, J.H.6
  • 97
    • 77957799898 scopus 로고    scopus 로고
    • Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway
    • PMID:20675655
    • Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM, Vaziri C. Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. J Biol Chem 2010; 285:31525-36; PMID:20675655; http://dx.doi.org/10.1074/jbc.M110.138206.
    • (2010) J Biol Chem , vol.285 , pp. 31525-31536
    • Song, I.Y.1    Palle, K.2    Gurkar, A.3    Tateishi, S.4    Kupfer, G.M.5    Vaziri, C.6
  • 98
    • 77958499239 scopus 로고    scopus 로고
    • RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network
    • PMID:20937699
    • Geng L, Huntoon CJ, Karnitz LM. RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network. J Cell Biol 2010; 191:249-57; PMID:20937699; http://dx.doi.org/10.1083/jcb.201005101.
    • (2010) J Cell Biol , vol.191 , pp. 249-257
    • Geng, L.1    Huntoon, C.J.2    Karnitz, L.M.3
  • 99
    • 55849091416 scopus 로고    scopus 로고
    • Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells
    • PMID:18845679
    • Niimi A, Brown S, Sabbioneda S, Kannouche PL, Scott A, Yasui A, et al. Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. Proc Natl Acad Sci USA 2008; 105:16125-30; PMID:18845679; http://dx.doi.org/10.1073/pnas.0802727105.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16125-16130
    • Niimi, A.1    Brown, S.2    Sabbioneda, S.3    Kannouche, P.L.4    Scott, A.5    Yasui, A.6
  • 100
    • 79956007456 scopus 로고    scopus 로고
    • Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition
    • PMID:21478670
    • Palle K, Vaziri C. Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition. Cell Cycle 2011; 10:1625-38; PMID:21478670; http://dx.doi.org/10. 4161/cc.10.10.15617.
    • (2011) Cell Cycle , vol.10 , pp. 1625-1638
    • Palle, K.1    Vaziri, C.2
  • 101
    • 15044351968 scopus 로고    scopus 로고
    • Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland
    • PMID:15767672
    • Lazzerini Denchi E, Attwooll C, Pasini D, Helin K. Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland. Mol Cell Biol 2005; 25:2660-72; PMID:15767672; http://dx.doi.org/10. 1128/MCB.25.7.2660-72.2005.
    • (2005) Mol Cell Biol , vol.25 , pp. 2660-2672
    • Lazzerini Denchi, E.1    Attwooll, C.2    Pasini, D.3    Helin, K.4
  • 102
    • 72949103076 scopus 로고    scopus 로고
    • E2F1 represses beta-catenin/ TCF activity by direct upregulation of Siah1
    • PMID:20187294
    • Xie W, Jin L, Mei Y, Wu M. E2F1 represses beta-catenin/ TCF activity by direct upregulation of Siah1. J Cell Mol Med 2009; 13:1719-27; PMID:20187294; http://dx.doi.org/10.1111/j.1582-4934.2008.00423.x.
    • (2009) J Cell Mol Med , vol.13 , pp. 1719-1727
    • Xie, W.1    Jin, L.2    Mei, Y.3    Wu, M.4
  • 103
    • 79958288924 scopus 로고    scopus 로고
    • p53 governs telomere regulation feedback too, via TRF2
    • (Albany NY) PMID:21266744
    • Horikawa I, Fujita K, Harris CC. p53 governs telomere regulation feedback too, via TRF2. Aging (Albany NY) 2011; 3:26-32; PMID:21266744.
    • (2011) Aging , vol.3 , pp. 26-32
    • Horikawa, I.1    Fujita, K.2    Harris, C.C.3
  • 104
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • PMID:16273092
    • Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 2006; 439:353-7; PMID:16273092; http://dx.doi.org/10.1038/nature04296.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3    Wang, Q.4    Potti, A.5    Chasse, D.6
  • 105
    • 48949119363 scopus 로고    scopus 로고
    • Evaluation of biological pathways involved in chemotherapy response in breast cancer
    • PMID:18445275
    • Tordai A, Wang J, Andre F, Liedtke C, Yan K, Sotiriou C, et al. Evaluation of biological pathways involved in chemotherapy response in breast cancer. Breast Cancer Res 2008; 10:37; PMID:18445275; http://dx.doi.org/10.1186/ bcr2088.
    • (2008) Breast Cancer Res , vol.10 , pp. 37
    • Tordai, A.1    Wang, J.2    Andre, F.3    Liedtke, C.4    Yan, K.5    Sotiriou, C.6
  • 106
    • 77954929373 scopus 로고    scopus 로고
    • Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM
    • PMID:20534551
    • Wiedemeyer WR, Dunn IF, Quayle SN, Zhang J, Chheda MG, Dunn GP, et al. Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM. Proc Natl Acad Sci USA 2010; 107:11501-6; PMID:20534551; http://dx.doi.org/10.1073/pnas.1001613107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11501-11506
    • Wiedemeyer, W.R.1    Dunn, I.F.2    Quayle, S.N.3    Zhang, J.4    Chheda, M.G.5    Dunn, G.P.6


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