RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40

EMBO Reports

Volumn 7, Issue 9, 2006, Pages 927-932

  Simpson, Laura J ^a   Ross, Anna Laura ^a   Szüts, Dávid ^a   Alviani, Cherry A ^a   Oestergaard, Vibe H ^a   Patel, Ketan J ^a   Sale, Julian E ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CELL PROTEIN; CYCLINE; MUTANT PROTEIN; PROTEIN RAD18; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; FOWL; GENE MUTATION; GENETIC ANALYSIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SENSITIVITY ANALYSIS; SISTER CHROMATID EXCHANGE; UBIQUITINATION;

ANIMALS; CELL LINE; CELL PROLIFERATION; CHICKENS; DNA DAMAGE; DNA REPLICATION; MUTATION; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN PROCESSING, POST-TRANSLATIONAL; SISTER CHROMATID EXCHANGE; TRANSFECTION; UBIQUITIN;

AVES; VERTEBRATA;

EID: 33749510488     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7400777     Document Type: Article

References (25)

1. Bienko M et al (2005) Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science 310: 1821-1824
2. Chen S, Davies AA, Sagan D, Ulrich HD (2005) The RING finger ATPase Rad5p of Saccharomyces cerevisiae contributes to DNA double-strand break repair in a ubiquitin-independent manner. Nucleic Acids Res 33: 5878-5886
3. Frampton J, Irmisch A, Green CM, Neiss A, Trickey M, Ulrich HD, Furuya K, Watts FZ, Carr AM, Lehmann AR (2006) Postreplication repair and PCNA modification in Schizosaccharomyces pombe. Mol Biol Cell 7: 2976-2985
4. Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, Grompe M, D'Andrea AD (2001) Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell 7: 249-262
5. Haracska L, Torres-Ramos CA, Johnson RE, Prakash S, Prakash L (2004) Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae. Mol Cell Biol 24: 4267-4274
6. Higgins NP, Kato K, Strauss B (1976) A model for replication repair in mammalian cells. J Mol Biol 101: 417-425
7. Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419: 135-141
8. Huang TT, Nijman SM, Mirchandani KD, Galardy PJ, Cohn MA, Haas W, Gygi SP, Ploegh HL, Bernards R, D'Andrea AD (2006) Regulation of monoubiquitinated PCNA by DUB autocleavage. Nat Cell Biol 8: 339-347
9. Kannouche PL, Wing J, Lehmann AR (2004) Interaction of human DNA polymerase ηη with monoubiquitinated PCNA: A possible mechanism for the polymerase switch in response to DNA damage. Mol Cell 14: 491-500
10. Kumar S, Hedges SB (1998) A molecular timescale for vertebrate evolution. Nature 392: 917-920
11. Leach CA, Michael WM (2005) Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts. J Cell Biol 171: 947-954
12. Nijman SM, Huang TT, Dirac AM, Brummelkamp TR, Kerkhoven RM, D'Andrea AD, Bernards R (2005) The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol Cell 17: 331-339
13. Okada T, Sonoda E, Yamashita YM, Koyoshi S, Tateishi S, Yamaizumi M, Takata M, Ogawa O, Takeda S (2002) Involvement of vertebrate polk in Rad18-independent postreplication repair of UV damage. J Biol Chem 277: 48690-48695
14. Papouli E, Chen S, Davies AA, Huttner D, Krejci L, Sung P, Ulrich HD (2005) Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p. Mol Cell 19: 123-133
15. Pfander B, Moldovan GL, Sacher M, Hoege C, Jentsch S (2005) SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature 436: 428-433
16. Ross AL, Sale JE (2006) The catalytic activity of REV1 is employed during immunoglobulin gene diversification in DT40. Mol Immunol 43: 1587-1594
17. Ross AL, Simpson LJ, Sale JE (2005) Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1. Nucleic Acids Res 33: 1280-1289
18. Shen X, Jun S, O'Neal LE, Sonoda E, Bemark M, Sale JE, Li L (2006) REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA). J Biol Chem 281: 13869-13872
19. Simpson LJ, Sale JE (2003) Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line. EMBO J 22: 1654-1664
20. Simpson LJ, Sale JE (2005) UBE2V2 (MMS2) is not required for effective immunoglobulin gene conversion or DNA damage tolerance in DT40. DNA Repair (Amst) 4: 503-510
21. Stelter P, Ulrich HD (2003) Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature 425: 188-191
22. Tateishi S, Sakuraba Y, Masuyama S, Inoue H, Yamaizumi M (2000) Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens. Proc Natl Acad Sci USA 97: 7927-7932
23. Tateishi S, Niwa H, Miyazaki J, Fujimoto S, Inoue H, Yamaizumi M (2003) Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells. Mol Cell Biol 23: 474-481
24. Watanabe K, Tateishi S, Kawasuji M, Tsurimoto T, Inoue H, Yamaizumi M (2004) Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. EMBO J 23: 3886-3896
25. Yamashita YM, Okada T, Matsusaka T, Sonoda E, Zhao GY, Araki K, Tateishi S, Yamaizumi M, Takeda S (2002) RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells. EMBO J 21: 5558-5566