Rad18 E3 ubiquitin ligase activity mediates fanconi anemia pathway activation and cell survival following DNA topoisomerase 1 inhibition

Cell Cycle

Volumn 10, Issue 10, 2011, Pages 1625-1638

  Palle, Komaraiah ^a   Vaziri, Cyrus ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Camptothecin; Double strand breaks; Fanconi anemia; Rad18; Topoisomerase I

Indexed keywords

BRCA2 PROTEIN; CAMPTOTHECIN; CELL CYCLE PROTEIN; CELL DIVISION CYCLE 45; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE ETA; DNA TOPOISOMERASE; DOUBLE STRANDED DNA; FANCONI ANEMIA GROUP A PROTEIN; FANCONI ANEMIA GROUP D2 PROTEIN; NIBRIN; PROTEIN P53; PYRIMIDINE DIMER; RAD18 PROTEIN; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL SURVIVAL; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE; DNA SYNTHESIS; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME INHIBITION; FANCONI ANEMIA; FIBROBLAST; HUMAN; HUMAN CELL; UBIQUITINATION;

EID: 79956007456     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.10.15617     Document Type: Article

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