메뉴 건너뛰기




Volumn 9, Issue 1, 2012, Pages 48-62

Insight into the biomarkers as the novel anti-psoriatic drug discovery tool: A contemporary viewpoint

Author keywords

Biological agents; Biomarkers; Drug targeting; Gene marker; Psoriasis

Indexed keywords

ADALIMUMAB; ALEFACEPT; ANTIPSORIASIS AGENT; ARACHIDONIC ACID; BASILIXIMAB; BRIAKINUMAB; CERTOLIZUMAB PEGOL; CYTOKINE; DACLIZUMAB; DENILEUKIN DIFTITOX; EFALIZUMAB; EMBREL; ENZYME; ETANERCEPT; HLA ANTIGEN; INFLIXIMAB; MEDIMMUNE; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPEPTIDE; PEPTIDE; PROTEIN CDC42; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; RECOMBINANT INTERLEUKIN 10; RECOMBINANT INTERLEUKIN 11; SIPLIZUMAB; STAT PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; UNINDEXED DRUG; USTEKINUMAB;

EID: 84858171449     PISSN: 15701638     EISSN: 18756220     Source Type: Journal    
DOI: 10.2174/157016312799304516     Document Type: Review
Times cited : (26)

References (219)
  • 1
    • 0036999044 scopus 로고    scopus 로고
    • Medical backgrounder: Psoriasis
    • DOI 10.1358/dot.2002.38.12.820102
    • Travis L, Weinberg JM. Medical backgrounder: psoriasis. Drugs Today 2002; 38: 847-65. (Pubitemid 36245174)
    • (2002) Drugs of Today , vol.38 , Issue.12 , pp. 847-865
    • Travis, L.1    Weinberg, J.M.2
  • 2
    • 0037420518 scopus 로고    scopus 로고
    • Psoriasis
    • Lebwohl M: Psoriasis. Lancet 2003; 361: 1197-04.
    • (2003) Lancet , vol.361 , pp. 1197-1204
    • Lebwohl, M.1
  • 3
    • 0035724176 scopus 로고    scopus 로고
    • Psoriasis epidemiology and clinical spectrum
    • Christophers E. Psoriasis epidemiology and clinical spectrum. Clin Exp Dermatol 2001; 26: 314-20.
    • (2001) Clin Exp Dermatol , vol.26 , pp. 314-320
    • Christophers, E.1
  • 4
    • 0029836758 scopus 로고    scopus 로고
    • Psoriasis in the community: Prevalence, severity and patients' beliefs and attitudes towards the disease
    • Nevitt GJ, Hutchinson PE. Psoriasis in the community: prevalence, severity and patients, beliefs and attitudes towards the disease. Br J Dermatol 1996; 135: 533-7. (Pubitemid 26340262)
    • (1996) British Journal of Dermatology , vol.135 , Issue.4 , pp. 533-537
    • Nevitt, G.J.1    Hutchinson, P.E.2
  • 7
    • 33847279025 scopus 로고    scopus 로고
    • Pathogenesis and therapy of psoriasis
    • Lowes MA, Bowcock AM, Krueger, JG. Pathogenesis and therapy of psoriasis. Nature 2007; 445: 866-73.
    • (2007) Nature , vol.445 , pp. 866-873
    • Lowes, M.A.1    Bowcock, A.M.2    Krueger, J.G.3
  • 8
    • 54249083259 scopus 로고    scopus 로고
    • Inhibitory effect of panduratin A on UV-induced activation of mitogen-activated protein kinases (MAPKs) in dermal fibroblast cells
    • Shim JS, Kwon YY, Han YS, Hwang JK. Inhibitory effect of panduratin A on UV-induced activation of mitogen-activated protein kinases (MAPKs) in dermal fibroblast cells. Planta Med 2008; 74: 1446-50.
    • (2008) Planta Med , vol.74 , pp. 1446-1450
    • Shim, J.S.1    Kwon, Y.Y.2    Han, Y.S.3    Hwang, J.K.4
  • 11
    • 0032986504 scopus 로고    scopus 로고
    • Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis
    • Nickoloff BJ, Wrone-Smith T. Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis. Am J Pathol 1999; 155: 145-58. (Pubitemid 29318713)
    • (1999) American Journal of Pathology , vol.155 , Issue.1 , pp. 145-158
    • Nickoloff, B.J.1    Wrone-Smith, T.2
  • 12
    • 0024521715 scopus 로고
    • Predominance of 'memory' T cells (CD4+, CDw29+) over 'naive' T cells (CD4+, CD45R+) in both normal and diseased human skin
    • DOI 10.1007/BF00424268
    • Bos JD, Hagenaars C, Das PK, Krieg SR, Voorn WJ, Kapsenberg ML. Predominance of "memory" T cells (CD4+, CDw29+) over "naive" T cells (CD4+, CD45R+) in both normal and diseased human skin. Arch Dermatol Res 1989: 281: 24-30. (Pubitemid 19064135)
    • (1989) Archives of Dermatological Research , vol.281 , Issue.1 , pp. 24-30
    • Bos, J.D.1    Hagenaars, C.2    Das, P.K.3    Krieg, S.R.4    Voorn, W.J.5    Kapsenberg, M.L.6
  • 13
    • 0020595264 scopus 로고
    • Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies
    • Bos JD, Hulsebosch HJ, Krieg SR, Bakker PM, Cormane RH. Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies. Arch Dermatol Res 1983; 275: 181-9. (Pubitemid 13056614)
    • (1983) Archives of Dermatological Research , vol.275 , Issue.3 , pp. 181-189
    • Bos, J.D.1    Hulsebosch, H.J.2    Krieg, S.R.3
  • 14
    • 0025896576 scopus 로고
    • Proliferating cells in psoriatic dermis are comprised primarily of T cells, endothelial cells, and factor XIIIa+ perivascular dendritic cells
    • Morganroth GS, Chan LS, Weinstein GD, Voorhees JJ, Cooper KD. Proliferating cells in psoriatic dermis are comprised primarily of T cells, endothelial cells, and factor XIIIa+ perivascular dendritic cells. J Invest Dermatol 1991: 96: 333-40.
    • (1991) J Invest Dermatol , vol.96 , pp. 333-340
    • Morganroth, G.S.1    Chan, L.S.2    Weinstein, G.D.3    Voorhees, J.J.4    Cooper, K.D.5
  • 15
    • 0030942048 scopus 로고    scopus 로고
    • Lymphocyte activation in health and disease
    • Berridge MJ. Lymphocyte activation in health and disease. Crit Rev Immunol 1997: 17: 155-178. (Pubitemid 27161350)
    • (1997) Critical Reviews in Immunology , vol.17 , Issue.2 , pp. 155-178
    • Berridge, M.J.1
  • 17
    • 0036072614 scopus 로고    scopus 로고
    • Targeting T cell costimulation in autoimmune disease
    • DOI 10.1517/14728222.6.3.275
    • Racke MK, Stuart RW. Targeting T cell costimulation in autoimmune disease. Expert Opin Ther Targets 2002; 6: 275-89. (Pubitemid 34662101)
    • (2002) Expert Opinion on Therapeutic Targets , vol.6 , Issue.3 , pp. 275-289
    • Stuart, R.W.1    Racke, M.K.2
  • 18
    • 0027439191 scopus 로고
    • The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper Type 1 cell-mediated response
    • Uyemura K, Yamamura M, Fivenson DF, Modlin RL, Nickoloff BJ. The cytokine network in lesional and lesionfree psoriatic skin is characterized by a T-helper type 1 cellmediated response. J Invest Dermatol 1993: 101: 701-05. (Pubitemid 23322027)
    • (1993) Journal of Investigative Dermatology , vol.101 , Issue.5 , pp. 701-705
    • Uyemura, K.1    Yamamura, M.2    Fivenson, D.F.3    Modlin, R.L.4    Nickoloff, B.J.5
  • 20
    • 0032729645 scopus 로고    scopus 로고
    • The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines interferongamma, IL-2 and tumor necrosis factor-alpha defining TCI (cytotoxic T lymphocyte) and THI effector populations a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients
    • Austin LM, Ozawa M, Kikuchi T, Walters IB, Krueger JG. The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines interferongamma, IL-2 and tumor necrosis factor-alpha defining TCI (cytotoxic T lymphocyte) and THI effector populations a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol 1999; 113: 752-9.
    • (1999) J Invest Dermatol , vol.113 , pp. 752-759
    • Austin, L.M.1    Ozawa, M.2    Kikuchi, T.3    Walters, I.B.4    Krueger, J.G.5
  • 21
    • 0029150307 scopus 로고
    • Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia
    • Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD. Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia. J Invest Dermatol 1995; 105 (Suppl): 89S-94S.
    • (1995) J Invest Dermatol , vol.105 , Issue.SUPPL.
    • Bata-Csorgo, Z.1    Hammerberg, C.2    Voorhees, J.J.3    Cooper, K.D.4
  • 22
    • 0034805313 scopus 로고    scopus 로고
    • Treatment of psoriasis. Part 1. Topical therapy and phototherapy
    • DOI 10.1067/mjd.2001.117046
    • Lebwohl M, Ali S. Treatment of psoriasis Topical therapy and phototherapy. J Am Acad Dermatol 2001; 45: 487-98. (Pubitemid 32917240)
    • (2001) Journal of the American Academy of Dermatology , vol.45 , Issue.4 , pp. 487-498
    • Lebwohl, M.1    Ali, S.2
  • 23
  • 26
    • 0035069606 scopus 로고    scopus 로고
    • The impact of psoriasis on quality of life: Results of a 1998 National Psoriasis Foundation Patient-Membership Survey
    • Krueger G, Koo J, Lebwohl M, Menter A, Stern RS, Rolstad T. The Impact of Psoriasis on Quality of Life. Results a 1998 Natl Psoriasis Foundation Patient-Membership Survey. Arch Dermatol 2001; 137: 280-84. (Pubitemid 32240779)
    • (2001) Archives of Dermatology , vol.137 , Issue.3 , pp. 280-284
    • Krueger, G.1    Koo, J.2    Lebwohl, M.3    Menter, A.4    Stern, R.S.5    Rolstad, T.6
  • 28
    • 0036718359 scopus 로고    scopus 로고
    • The suitability of quality-of-life questionnaires for psoriasis research: A systematic literature review
    • De Korte J, Mombers FM, Sprangers MA, Bos JD. The suitability of quality-of-life questionnaires for psoriasis research a systematic literature review. Arch Dermatol 2002; 138: 1221-7. (Pubitemid 35025697)
    • (2002) Archives of Dermatology , vol.138 , Issue.9 , pp. 1221-1227
    • De Korte, J.1    Mombers, F.M.C.2    Sprangers, M.A.G.3    Bos, J.D.4    Corona, R.5
  • 30
    • 0030765915 scopus 로고    scopus 로고
    • Triggering factors
    • DOI 10.1016/S0738-081X(97)00024-2, PII S0738081X97000242
    • Tagami H. Triggering factors. Clin Dermatol 1997; 15: 677-85. (Pubitemid 27411302)
    • (1997) Clinics in Dermatology , vol.15 , Issue.5 , pp. 677-685
    • Tagami, H.1
  • 31
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group
    • Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 2001; 69: 89-95.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
  • 32
    • 47349119414 scopus 로고    scopus 로고
    • Biological biomarkers in psoriatic disease. A review
    • de Vlam K, Gottlieb AB, Fitzgerald O. Biological biomarkers in psoriatic disease. A review. J Rheumatol 2008; 35: 1443-8. (Pubitemid 352000801)
    • (2008) Journal of Rheumatology , vol.35 , Issue.7 , pp. 1443-1448
    • De Vlam, K.1    Gottlieb, A.B.2    FitzGerald, O.3
  • 34
    • 2642573655 scopus 로고    scopus 로고
    • Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis
    • DOI 10.1111/j.1365-4632.2004.02222.x
    • Sander CS, Chang H, Hamm F, Elsner P, Thiele JJ. Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis. Int J Dermatol 2004; 43: 326-35. (Pubitemid 38714593)
    • (2004) International Journal of Dermatology , vol.43 , Issue.5 , pp. 326-335
    • Sander, C.S.1    Chang, H.2    Hamm, F.3    Elsner, P.4    Thiele, J.J.5
  • 36
    • 0033105874 scopus 로고    scopus 로고
    • NADPH oxidase: An update
    • Babior BM. NADPH oxidase: an update. Blood 1999; 93: 1464-76. (Pubitemid 29102471)
    • (1999) Blood , vol.93 , Issue.5 , pp. 1464-1476
    • Babior, B.M.1
  • 38
    • 0032911057 scopus 로고    scopus 로고
    • The diversity of the lipoxygenase family. Many sequence data but little information on biological significance
    • DOI 10.1016/S0014-5793(99)00396-8, PII S0014579399003968
    • Kuhn H, Thiele BJ. The diversity of the lipoxygenase family many sequence data but little information on biological significance. FEBS Lett 1999; 449: 7-11. (Pubitemid 29182660)
    • (1999) FEBS Letters , vol.449 , Issue.1 , pp. 7-11
    • Kuhn, H.1    Thiele, B.J.2
  • 39
    • 0019195393 scopus 로고
    • Prostaglandins arachidonic acid and inflammation
    • Kuehl Jr FA, Egan RW. Prostaglandins arachidonic acid and inflammation. Science. 1980; 210: 978-84.
    • (1980) Science , vol.210 , pp. 978-984
    • Kuehl Jr., F.A.1    Egan, R.W.2
  • 41
    • 8544224992 scopus 로고    scopus 로고
    • Metal-induced oxidative stress and signal transduction
    • DOI 10.1016/j.freeradbiomed.2004.09.010, PII S0891584904007191
    • Leonard SS, Harris GK, Shi X. Metal-induced oxidative stress and signal transduction. Free Radic Biol Med 2004; 37: 1921-42. (Pubitemid 39491314)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.12 , pp. 1921-1942
    • Leonard, S.S.1    Harris, G.K.2    Shi, X.3
  • 42
    • 1842844732 scopus 로고    scopus 로고
    • Radiation-induced oxidative DNA damage, 8-oxoguanine, in human peripheral T cells
    • Ogawa Y, Kobayashi T, Nishioka A, et al. Radiation-induced oxidative DNA damage, 8-oxoguanine, in human peripheral T cells. Int J Mol Med 2003; 11: 27-32.
    • (2003) Int J Mol Med , vol.11 , pp. 27-32
    • Ogawa, Y.1    Kobayashi, T.2    Nishioka, A.3
  • 43
    • 0037861837 scopus 로고    scopus 로고
    • UV-induced free radicals in the skin detected by ESR spectroscopy and imaging using nitroxides
    • DOI 10.1016/S0891-5849(03)00241-7
    • Herrling T, Fuchs J, Rehberg J, Groth N. UV-induced free radicals in the skin detected by ESR spectroscopy and imaging using nitroxides. Free Radic Biol Med 2003; 35: 59-67. (Pubitemid 36782337)
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.1 , pp. 59-67
    • Herrling, T.1    Fuchs, J.2    Rehberg, J.3    Groth, N.4
  • 44
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 1999; 57: 727- 41.
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 46
    • 33751112220 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of skin disease
    • DOI 10.1038/sj.jid.5700340, PII 5700340
    • Bickers DR, Athar M. Oxidative stress in the pathogenesis of skin disease. J Invest Dermatol 2006; 126: 2565-75. (Pubitemid 44764040)
    • (2006) Journal of Investigative Dermatology , vol.126 , Issue.12 , pp. 2565-2575
    • Bickers, D.R.1    Athar, M.2
  • 47
    • 0032213375 scopus 로고    scopus 로고
    • Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing
    • Hampton MB, Kettle AJ, Winterbourn CC. Inside the neutrophil phagosome oxidants, myeloperoxidase and bacterial killing. Blood 1998; 92: 3007-17. (Pubitemid 28492304)
    • (1998) Blood , vol.92 , Issue.9 , pp. 3007-3017
    • Hampton, M.B.1    Kettle, A.J.2    Winterbourn, C.C.3
  • 49
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants oxidative stress and the biology of ageing
    • Finkel T, Holbrook NJ. Oxidants oxidative stress and the biology of ageing. Nature 2000; 408: 239-47.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 50
    • 0036038079 scopus 로고    scopus 로고
    • Psoriasis is mediated by a cutaneous defect triggered by activated immunocytes: Induction of psoriasis by cells with natural killer receptors
    • DOI 10.1046/j.1523-1747.2002.01812.x
    • Gilhar A, Ullmann Y, Kerner H, et al. Psoriasis is mediated by a cutaneous defect triggered by activated immunocytes: induction of psoriasis by cells with natural killer receptors. J Invest Dermatol 2002; 119: 384-91. (Pubitemid 35001948)
    • (2002) Journal of Investigative Dermatology , vol.119 , Issue.2 , pp. 384-391
    • Gilhar, A.1    Ullmann, Y.2    Kerner, H.3    Assy, B.4    Shalaginov, R.5    Serafimovich, S.6    Kalish, R.S.7
  • 55
    • 33745209428 scopus 로고    scopus 로고
    • Prominent production of IL-20 by CD68+/ CD11c+ myeloid-derived cells in psoriasis gene regulation and cellular effects
    • Wang F, Lee E, Lowes MA, et al. Prominent production of IL-20 by CD68+/ CD11c+ myeloid-derived cells in psoriasis gene regulation and cellular effects. J Invest Dermatol 2006; 126: 1590-99.
    • (2006) J Invest Dermatol , vol.126 , pp. 1590-1599
    • Wang, F.1    Lee, E.2    Lowes, M.A.3
  • 56
    • 0025296817 scopus 로고
    • Serum-soluble interleukin 2 receptor in psoriasis failure to reflect clinical improvement
    • Kemmett D, Symons JA, Colver GB, Duff GW. Serum-soluble interleukin 2 receptor in psoriasis failure to reflect clinical improvement. Acta Derm Venereol 1990; 70: 264-66.
    • (1990) Acta Derm Venereol , vol.70 , pp. 264-266
    • Kemmett, D.1    Symons, J.A.2    Colver, G.B.3    Duff, G.W.4
  • 58
    • 35348876050 scopus 로고    scopus 로고
    • IL-15 and psoriasis: Another genetic link to Th17?
    • DOI 10.1038/sj.jid.5700855, PII 5700855
    • Elder JT. IL-15 and psoriasis another genetic link to Th17. J Invest Dermatol 2007; 127: 2495-7. (Pubitemid 47585052)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.11 , pp. 2495-2497
    • Elder, J.T.1
  • 59
    • 40749156754 scopus 로고    scopus 로고
    • Identification of cellular pathways of type 1q Th17 T cells, and TNF- And inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis
    • Haider AS, Lowes MA, Suarez-Farinas M, et al. Identification of cellular pathways of type 1q Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis. J Immunol 2008; 180: 1913-20.
    • (2008) J Immunol , vol.180 , pp. 1913-1920
    • Haider, A.S.1    Lowes, M.A.2    Suarez-Farinas, M.3
  • 60
    • 0031691282 scopus 로고    scopus 로고
    • Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes
    • DOI 10.1046/j.1523-1747.1998.00347.x
    • Teunissen MB, Koomen CW, de Waal Malefyt R, Wierenga EA, Bos JD. Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes. J Invest Dermatol1998; 111: 645-9. (Pubitemid 28452327)
    • (1998) Journal of Investigative Dermatology , vol.111 , Issue.4 , pp. 645-649
    • Teunissen, M.B.M.1    Koomen, C.W.2    De Waal, M.R.3    Wierenga, E.A.4    Bos, J.D.5
  • 61
    • 0032939560 scopus 로고    scopus 로고
    • IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: Synergistic or antagonist effects with IFN-gamma and TNF-alpha
    • Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes synergistic or antagonist effects with IFN-gamma and TNF-alpha. J Immunol 1999; 162: 494-502. (Pubitemid 29018959)
    • (1999) Journal of Immunology , vol.162 , Issue.1 , pp. 494-502
    • Albanesi, C.1    Cavani, A.2    Girolomoni, G.3
  • 62
    • 0033911218 scopus 로고    scopus 로고
    • Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4- induced activation of human keratinocytes
    • DOI 10.1046/j.1523-1747.2000.00041.x
    • Albanesi C, Scarponi C, Cavani A, Federici M, Nasorri F, Girolomoni G. Interleukin-17 is produced by both Th1 and Th2 lymphocytes and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes. J Invest Dermatol 2000; 115: 81-7. (Pubitemid 30470196)
    • (2000) Journal of Investigative Dermatology , vol.115 , Issue.1 , pp. 81-87
    • Albanesi, C.1    Scarponi, C.2    Cavani, A.3    Federici, M.4    Nasorri, F.5    Girolomoni, G.6
  • 63
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide
    • Xie QW, Whisnant R, Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. J Exp Med 1993; 177: 1779-84. (Pubitemid 23146145)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.6 , pp. 1779-1784
    • Xie, Q.-W.1    Whisnant, R.2    Nathan, C.3
  • 65
    • 0030687496 scopus 로고    scopus 로고
    • Altered expression of keratinocyte growth factor and its receptor in psoriasis
    • Finch PW, Murphy F, Cardinale I, Krueger JG. Altered expression of keratinocyte growth factor and its receptor in psoriasis. Am J Pathol 1997; 151: 1619-28. (Pubitemid 27527924)
    • (1997) American Journal of Pathology , vol.151 , Issue.6 , pp. 1619-1628
    • Finch, P.W.1    Murphy, F.2    Cardinale, I.3    Krueger, J.G.4
  • 67
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E, Mahadevan LC. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 1995; 20: 117-22.
    • (1995) Trends Biochem Sci , vol.20 , pp. 117-122
    • Cano, E.1    Mahadevan, L.C.2
  • 68
    • 0028073283 scopus 로고
    • MAPKs: New JNK expands the group
    • DOI 10.1016/0968-0004(94)90132-5
    • Davis RJ, MAPKs new JNK expands the group. Trends Biochem Sci 1994; 19: 470-3. (Pubitemid 24342759)
    • (1994) Trends in Biochemical Sciences , vol.19 , Issue.11 , pp. 470-473
    • Davis, R.J.1
  • 69
    • 0036876857 scopus 로고    scopus 로고
    • Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis
    • DOI 10.1016/S0923-1811(02)00064-6, PII S0923181102000646
    • Takahashi H, Ibe M, Nakamura S, Ishida-Yamamoto A, Hashimoto Y, Iizuka H. Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis. J Dermatol Sci 2002; 30: 94-99. (Pubitemid 36159019)
    • (2002) Journal of Dermatological Science , vol.30 , Issue.2 , pp. 94-99
    • Takahashi, H.1    Ibe, M.2    Nakamura, S.3    Ishida-Yamamoto, A.4    Hashimoto, Y.5    Iizuka, H.6
  • 71
    • 36148934536 scopus 로고    scopus 로고
    • Expression and localization of the activated mitogen-activated protein kinase in lesional psoriatic skin
    • Yu XJ, Li CY, Dai HY, et al. Expression and localization of the activated mitogen-activated protein kinase in lesional psoriatic skin. Exp Mol Pathol 2007; 83: 413-18.
    • (2007) Exp Mol Pathol , vol.83 , pp. 413-418
    • Yu, X.J.1    Li, C.Y.2    Dai, H.Y.3
  • 73
    • 0027444597 scopus 로고
    • AVP-induced activation of MAP kinase in vascular smooth muscle cells is mediated through protein kinase
    • Kribben A, Wieder ED, Li X, van, et al. AVP-induced activation of MAP kinase in vascular smooth muscle cells is mediated through protein kinase. C Am J Physiol 1993; 265: 939-45.
    • (1993) C Am J Physiol , vol.265 , pp. 939-945
    • Kribben, A.1    Wieder, E.D.2    Van Li, X.3
  • 74
    • 0027171138 scopus 로고
    • Activation of mitogen-activated protein kinase/extracellular signal- regulated kinase kinase by G protein and tyrosine kinase oncoproteins
    • Gardner AM, Vaillancourt RR, Johnson GL. Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins. J Biol Chem 1993; 268: 17896-901. (Pubitemid 23260303)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.24 , pp. 17896-17901
    • Gardner, A.M.1    Vaillancourt, R.R.2    Johnson, G.L.3
  • 76
    • 0028138774 scopus 로고
    • Activation of human monocytes via a non-neurokinin substance-P receptor that is coupled to G protein calcium phospholipaseD MAP kinase and IL-6 production
    • Kavelaars A, Broeke D, Jeurissen F, et al. Activation of human monocytes via a non-neurokinin substance-P receptor that is coupled to G protein calcium phospholipaseD MAP kinase and IL-6 production. J Immunol 1994; 153: 3691-9.
    • (1994) J Immunol , vol.153 , pp. 3691-3699
    • Kavelaars, A.1    Broeke, D.2    Jeurissen, F.3
  • 77
    • 0028826729 scopus 로고
    • Differential activation of mitogen-activated protein kinase and S6 kinase signaling pathways by 12-O-tetradecanoylphorbol-13-acetate (TPA) and insulin: Evidence for involvement of a TPA-stimulated protein-tyrosine kinase
    • Seger R, Biener Y, Feinstein R, Hanoch T, Gazit A, Zick Y. Differential activation of mitogen-activated protein kinase and S6 kinase signaling pathways by 12-O-tetradecanoylphorbol-13-acetate (TPA) and insulin: evidence for involvement of a TPA-stimulated protein-tyrosine kinase. J Biol Chem 1995; 270: 28325-30.
    • (1995) J Biol Chem , vol.270 , pp. 28325-28330
    • Seger, R.1    Biener, Y.2    Feinstein, R.3    Hanoch, T.4    Gazit, A.5    Zick, Y.6
  • 78
    • 0028843581 scopus 로고
    • Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor
    • Gamou S, Shimizu N. Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor. FEBS Lett 1995; 357: 161-4.
    • (1995) FEBS Lett , vol.357 , pp. 161-164
    • Gamou, S.1    Shimizu, N.2
  • 80
    • 0026757051 scopus 로고
    • Activation of MAP kinases by calcium-dependent and calcium-independent pathways stimulation by thapsigargin and epidermal growth factor
    • Chao TS, Byron KL, Lee KM, Villereal M, Rosner MR. Activation of MAP kinases by calcium-dependent and calcium-independent pathways stimulation by thapsigargin and epidermal growth factor. J Biol Chem 1992; 267: 19876-83.
    • (1992) J Biol Chem , vol.267 , pp. 19876-19883
    • Chao, T.S.1    Byron, K.L.2    Lee, K.M.3    Villereal, M.4    Rosner, M.R.5
  • 82
    • 0029154733 scopus 로고
    • Protein tyrosine kinase PYK2 involved in Ca(2+)- Induced regulation of ion channel and MAP kinase functions
    • Lev S, Moreno H, Martinez R, et al. Protein tyrosine kinase PYK2 involved in Ca(2+)- induced regulation of ion channel and MAP kinase functions. Nature 1995; 376: 737-45.
    • (1995) Nature , vol.376 , pp. 737-745
    • Lev, S.1    Moreno, H.2    Martinez, R.3
  • 83
    • 0028277844 scopus 로고
    • Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras
    • DOI 10.1016/0896-6273(94)90438-3
    • Rosen LB, Ginty DD, Weber MJ, Greenberg ME. Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 1994; 12: 1207-21. (Pubitemid 24186790)
    • (1994) Neuron , vol.12 , Issue.6 , pp. 1207-1221
    • Rosen, L.B.1    Ginty, D.D.2    Weber, M.J.3    Greenberg, M.E.4
  • 85
    • 0034491933 scopus 로고    scopus 로고
    • Lck and CaM-kinase
    • DOI 10.1016/S0161-5890(00)00087-0, PII S0161589000000870
    • Franklin RA, Atherfold PA, McCubrey JA. Calcium-induced ERK activation in human T lymphocytes occurs via p56 (Lck) and CaM-kinase. Mol Immunol 2000; 37: 675-83. (Pubitemid 32112655)
    • (2000) Molecular Immunology , vol.37 , Issue.11 , pp. 675-683
    • Franklin, R.A.1    Atherfold, P.A.2    McCubrey, J.A.3
  • 86
    • 0036080595 scopus 로고    scopus 로고
    • CaM kinase II-dependent activation of tyrosine kinases and ERK1/2 in vascular smooth muscle
    • Ginnan R, Singer HA. CaM kinase II-dependent activation of tyrosine kinases and ERK1/2 in vascular smooth muscle. Am J Physiol Cell Physiol 2002; 282: C754-C61.
    • (2002) Am J Physiol Cell Physiol , vol.282
    • Ginnan, R.1    Singer, H.A.2
  • 88
    • 0036876857 scopus 로고    scopus 로고
    • Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis
    • DOI 10.1016/S0923-1811(02)00064-6, PII S0923181102000646
    • Takahashi H, Ibe M, Nakamura S, Ishida-Yamamoto A, Hashimoto Y, Iizuka H. Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis. J Dermatol Sci 2002; 30: 94-9. (Pubitemid 36159019)
    • (2002) Journal of Dermatological Science , vol.30 , Issue.2 , pp. 94-99
    • Takahashi, H.1    Ibe, M.2    Nakamura, S.3    Ishida-Yamamoto, A.4    Hashimoto, Y.5    Iizuka, H.6
  • 90
    • 0027994002 scopus 로고
    • An osmosensing signal transduction pathway in mammalian cells
    • Galcheva-Gargova Z, Derijard B, Wu IH, Davis RJ. An osmosensing signal transduction pathway in mammalian cells. Science1994; 265: 806-8. (Pubitemid 24266144)
    • (1994) Science , vol.265 , Issue.5173 , pp. 806-808
    • Galcheva-Gargova, Z.1    Derijard, B.2    Wu, I.-H.3    Davis, R.J.4
  • 91
    • 33645771481 scopus 로고    scopus 로고
    • Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: Involvement of JNK and ERK MAP kinases
    • Conde de la, Rosa L, Schoemaker MH, et al. Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases. J Hepatol 2006; 44: 918-29.
    • (2006) J Hepatol , vol.44 , pp. 918-929
    • Conde De La, R.L.1    Schoemaker, M.H.2
  • 93
    • 9144253936 scopus 로고    scopus 로고
    • The ASK1-MAP kinase cascades in mammalian stress response
    • DOI 10.1093/jb/mvh134
    • Matsukawa J, Matsuzawa A, Takeda K, Ichijo H. The ASK1-MAP kinase cascades in mammalian stress response. J Biochem 2004; 136: 261-65. (Pubitemid 39545783)
    • (2004) Journal of Biochemistry , vol.136 , Issue.3 , pp. 261-265
    • Matsukawa, J.1    Matsuzawa, A.2    Takeda, K.3    Ichijo, H.4
  • 94
    • 0033140337 scopus 로고    scopus 로고
    • Antioxidants Differentially Regulate Activation of Nuclear Factor-kappaB, Activator Protein-1, c-Jun Amino-Terminal Kinases, and Apoptosis Induced by Tumor Necrosis Factor: Evidence that JNK and NF-kappaB Activation Are Not Linked to Apoptosis
    • Shrivastava A, Aggarwal BB. Antioxidants differentially regulate activation of nuclear factor-kappa B, activator protein-1, c-jun amino-terminal kinases, and apoptosis induced by tumor necrosis factor: evidence that JNK and NF-kappa B activation are not linked to apoptosis. Antioxid Redox Signaling 1999; 1: 181-91. (Pubitemid 129619774)
    • (1999) Antioxidants and Redox Signaling , vol.1 , Issue.2 , pp. 181-191
    • Shrivastava, A.1    Aggarwal, B.B.2
  • 96
    • 0032955803 scopus 로고    scopus 로고
    • Activation pattern of mitogen-activated protein kinases elicited by peroxynitrite: Attenuation by selenite supplementation
    • DOI 10.1016/S0014-5793(99)00372-5, PII S0014579399003725
    • Schieke SM, Briviba K, Klotz LO, et al. Activation pattern of mitogen Activated Protein kinases elicited by peroxynitrite attenuation by selenite supplementation. FEBS Lett 1999; 448: 301-3. (Pubitemid 29168508)
    • (1999) FEBS Letters , vol.448 , Issue.2-3 , pp. 301-303
    • Schieke, S.M.1    Briviba, K.2    Klotz, L.-O.3    Sies, H.4
  • 97
    • 0036019933 scopus 로고    scopus 로고
    • Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: Advanced findings from ASK1 knockout mice
    • Matsuzawa A, Nishitoh H, Tobiume K, Takeda K, Ichijo H. Physiological roles Of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice. Antioxid Redox Signaling 2002; 4: 415-25. (Pubitemid 34753381)
    • (2002) Antioxidants and Redox Signaling , vol.4 , Issue.3 , pp. 415-425
    • Matsuzawa, A.1    Nishitoh, H.2    Tobiume, K.3    Takeda, K.4    Ichijo, H.5
  • 98
    • 0029913510 scopus 로고    scopus 로고
    • Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c- Jun N-terminal kinase/stress-activated protein kinase pathway: A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family
    • DOI 10.1074/jbc.271.44.27225
    • Teramoto H, Coso OA, Miyata H, Igishi T, Miki T, Gutkind JS. Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway a role for mixed lineage kinase 3/protein-tyrosine kinase 1 a novel member of the mixed lineage kinase family. J Biol Chem 1996; 271: 27225-28. (Pubitemid 26367270)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.44 , pp. 27225-27228
    • Teramoto, H.1    Coso, O.A.2    Miyata, H.3    Igishi, T.4    Miki, T.5    Silvio, G.J.6
  • 99
    • 0030198344 scopus 로고    scopus 로고
    • Protein kinase cascades activated by stress and inflammatory cytokines
    • Kyriakis JM, Avruch J. Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays 1996; 18: 567-77. (Pubitemid 26311096)
    • (1996) BioEssays , vol.18 , Issue.7 , pp. 567-577
    • Kyriakis, J.M.1    Avruch, J.2
  • 100
    • 0036193378 scopus 로고    scopus 로고
    • MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts
    • DOI 10.1128/MCB.22.8.2871-2881.2002
    • Wiggin GR, Soloaga A, Foster JM, Murray-Tait V, Cohen P, Arthur JS. MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts. Mol Cell Biol 2002; 22: 2871-81 (Pubitemid 34263007)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.8 , pp. 2871-2881
    • Wiggin, G.R.1    Soloaga, A.2    Foster, J.M.3    Murray-Tait, V.4    Cohen, P.5    Arthur, J.S.C.6
  • 101
    • 0032479983 scopus 로고    scopus 로고
    • Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
    • DOI 10.1093/emboj/17.15.4426
    • Deak M, Clifton AD, Lucocq LM, Alessi DR. Mitogen and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38 and may mediate activation of CREB. EMBO J 1998; 17: 4426-41. (Pubitemid 28362632)
    • (1998) EMBO Journal , vol.17 , Issue.15 , pp. 4426-4441
    • Deak, M.1    Clifton, A.D.2    Lucocq, J.M.3    Alessi, D.R.4
  • 103
    • 33745209428 scopus 로고    scopus 로고
    • Prominent production of IL-20 by CD68+/ CD11c+ myeloid-derived cells in psoriasis gene regulation and cellular effects
    • Wang F, Lee E, Lowes MA, et al. Prominent production of IL-20 by CD68+/ CD11c+ myeloid-derived cells in psoriasis gene regulation and cellular effects. J Invest Dermatol 2006; 126: 1590-99
    • (2006) J Invest Dermatol , vol.126 , pp. 1590-1599
    • Wang, F.1    Lee, E.2    Lowes, M.A.3
  • 104
    • 0028117163 scopus 로고
    • Cytokine signal transduction
    • DOI 10.1016/0092-8674(94)90333-6
    • Kishimoto T, Taga T, Akira S. Cytokine signal transduction. Cell 1994; 76: 253-62. (Pubitemid 24046688)
    • (1994) Cell , vol.76 , Issue.2 , pp. 253-262
    • Kishimoto, T.1    Taga, T.2    Akirat, S.3
  • 105
    • 0037138370 scopus 로고    scopus 로고
    • Signaling through the JAK/STAT pathway, recent advances and future challenges
    • DOI 10.1016/S0378-1119(02)00398-0, PII S0378111902003980
    • Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW. Signaling through the JAK/STAT pathway recent advances and future challenges. Gene 2002; 285: 1-24. (Pubitemid 34246317)
    • (2002) Gene , vol.285 , Issue.1-2 , pp. 1-24
    • Kisseleva, T.1    Bhattacharya, S.2    Braunstein, J.3    Schindler, C.W.4
  • 106
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • DOI 10.1016/S0092-8674(02)00701-8
    • O'Shea JJ, Gadina M, Schreiber RD. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell (Suppl) 2002; 109: S121-31. (Pubitemid 34457857)
    • (2002) Cell , vol.109 , Issue.2 SUPPL. 1
    • OShea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 108
    • 33845718240 scopus 로고    scopus 로고
    • Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain
    • DOI 10.1101/gad.1485406
    • Mertens C, Zhong M, Krishnaraj R, Zou W, Chen X, Darnell JE Jr. Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain. Genes Dev 2006; 20: 3372-81. (Pubitemid 44969156)
    • (2006) Genes and Development , vol.20 , Issue.24 , pp. 3372-3381
    • Mertens, C.1    Zhong, M.2    Krishnaraj, R.3    Zou, W.4    Chen, X.5    Darnell Jr., J.E.6
  • 109
    • 34547108380 scopus 로고    scopus 로고
    • JAK-STAT signaling from interferons to cytokines
    • Schindler C, Levy DE, Decker T. JAK-STAT signaling from interferons to cytokines. J Biol Chem 2007; 282: 20059-63.
    • (2007) J Biol Chem , vol.282 , pp. 20059-20063
    • Schindler, C.1    Levy, D.E.2    Decker, T.3
  • 112
    • 33645960166 scopus 로고    scopus 로고
    • PKC zeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways
    • Moscat J, Rennert P, Diaz-Meco MT. PKC zeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways. Cell Death Differ 2006; 13: 702-11.
    • (2006) Cell Death Differ , vol.13 , pp. 702-711
    • Moscat, J.1    Rennert, P.2    Diaz-Meco, M.T.3
  • 113
    • 49549084651 scopus 로고    scopus 로고
    • Activation of keratinocyte protein kinase C zeta in psoriasis plaques
    • Zhao Y, Fishelevich R, Petrali JP, et al. Activation of keratinocyte protein kinase C zeta in psoriasis plaques. J Invest Dermatol 2008; 128: 2190-97.
    • (2008) J Invest Dermatol , vol.128 , pp. 2190-2197
    • Zhao, Y.1    Fishelevich, R.2    Petrali, J.P.3
  • 114
    • 0042525909 scopus 로고    scopus 로고
    • Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation
    • DOI 10.1093/emboj/cdg370
    • Duran A, Diaz-Meco MT, Moscat J. Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation. EMBO J 2003; 22: 3910-8. (Pubitemid 36975717)
    • (2003) EMBO Journal , vol.22 , Issue.15 , pp. 3910-3918
    • Duran, A.1    Diaz-Meco, M.T.2    Moscat, J.3
  • 115
    • 0035145916 scopus 로고    scopus 로고
    • Dislipidemia and oxidative stress in mild and in severe psoriasis as a risk for cardiovascular disease
    • DOI 10.1016/S0009-8981(00)00358-2, PII S0009898100003582
    • Rocha-Pereira P, Santos-Silva A, Rebelo I, Figueiredo A, Quintanilha A, Teixeira F. Dislipidemia and oxidative stress in mild and in severe psoriasis as a risk for cardiovascular disease. Clin Chim Acta 2001; 303: 33-9. (Pubitemid 32121803)
    • (2001) Clinica Chimica Acta , vol.303 , Issue.1-2 , pp. 33-39
    • Rocha-Pereira, P.1    Santos-Silva, A.2    Rebelo, I.3    Figueiredo, A.4    Quintanilha, A.5    Teixeira, F.6
  • 116
    • 33846694581 scopus 로고    scopus 로고
    • Accumulation of oxidized low density lipoprotein in psoriatic skin and changes of plasma lipid levels in psoriatic patients
    • Tekin NS, Tekin IO, Barut F, Sipahi EY. Accumulation of oxidized low density lipoprotein in psoriatic skin and changes of plasma lipid levels in psoriatic patients. Mediators Inflamm 2007; 2007: 78454.
    • (2007) Mediators Inflamm , vol.2007 , pp. 78454
    • Tekin, N.S.1    Tekin, I.O.2    Barut, F.3    Sipahi, E.Y.4
  • 119
    • 0036686105 scopus 로고    scopus 로고
    • Activity of superoxide dismutase and catalase and the level of lipid peroxidation products reactive with TBA in patients with psoriasis
    • Drewa G, Krzyzynska-Malinowska E, Wozniak A, et al. Activity of superoxide dismutase and catalase and the level of lipid peroxidation products reactive with TBA in patients with psoriasis. Med Sci Monit 2002; 8: BR338-BR43.
    • (2002) Med Sci Monit , vol.8
    • Drewa, G.1    Krzyzynska-Malinowska, E.2    Wozniak, A.3
  • 120
    • 0345425787 scopus 로고    scopus 로고
    • Antioxidants and lipid peroxidation status in the blood of patients with psoriasis
    • DOI 10.1016/S0009-8981(99)00150-3, PII S0009898199001503
    • Kokcam I, Naziroglu M. Antioxidants and lipid peroxidation status in the blood of patients with psoriasis. Clin Chim Acta 1999; 289: 23-31. (Pubitemid 29505196)
    • (1999) Clinica Chimica Acta , vol.289 , Issue.1-2 , pp. 23-31
    • Kokcam, I.1    Naziroglu, M.2
  • 121
    • 37049018807 scopus 로고    scopus 로고
    • PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparinbinding EGF-like growth factor
    • Romanowska M, al Yacoub N, Seidel H, et al. PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparinbinding EGF-like growth factor. J Invest Dermatol 2008; 128: 110- 24.
    • (2008) J Invest Dermatol , vol.128 , pp. 110-124
    • Romanowska, M.1    Al Yacoub, N.2    Seidel, H.3
  • 122
    • 0026710581 scopus 로고
    • Type I kerantinocyte transglutaminase: Expression in human skin and psoriasis
    • Schroeder WT, Thacher SM, Stewart-Galetka S, et al. Type I kerantinocyte transglutaminase: expression in human skin and psoriasis. J Invest Dermatol 1992; 99: 27-34.
    • (1992) J Invest Dermatol , vol.99 , pp. 27-34
    • Schroeder, W.T.1    Thacher, S.M.2    Stewart-Galetka, S.3
  • 123
    • 0036038079 scopus 로고    scopus 로고
    • Psoriasis is mediated by a cutaneous defect triggered by activated immunocytes: Induction of psoriasis by cells with natural killer receptors
    • DOI 10.1046/j.1523-1747.2002.01812.x
    • Gilhar A, Ullmann Y, Kerner H, et al. Psoriasis is mediated by a cutaneous defect triggered by activated immunocytes induction of psoriasis by cells with natural killer receptors. J Invest Dermatol 2002; 119: 384-91. (Pubitemid 35001948)
    • (2002) Journal of Investigative Dermatology , vol.119 , Issue.2 , pp. 384-391
    • Gilhar, A.1    Ullmann, Y.2    Kerner, H.3    Assy, B.4    Shalaginov, R.5    Serafimovich, S.6    Kalish, R.S.7
  • 124
    • 36249024235 scopus 로고    scopus 로고
    • Comparison of expression of heat-shock protein 60, Toll-like receptors 2 and 4, and T-cell receptor gammadelta in plaque and guttate psoriasis
    • DOI 10.1111/j.1600-0560.2007.00756.x
    • Seung NR, Park EJ, Kim CW, et al. Comparison of expression of heat-shock protein 60, Toll-like receptors 2 and 4 and T-cell receptor gammadelta in plaque and guttate psoriasis. J Cutan Pathol 2007; 34: 903-11. (Pubitemid 350132007)
    • (2007) Journal of Cutaneous Pathology , vol.34 , Issue.12 , pp. 903-911
    • Seung, N.R.1    Park, E.J.2    Kim, C.W.3    Kim, K.H.4    Kim, K.J.5    Cho, H.J.6    Park, H.R.7
  • 126
    • 0033024635 scopus 로고    scopus 로고
    • Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium
    • DOI 10.1046/j.1523-1747.1999.00512.x
    • Lucke T, Choudhry R, Thom R, Selmer IS, Burden AD, Hodgins MB. Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis vaginal epithelium and buccal epithelium. J Invest Dermatol 1999; 112: 354-61. (Pubitemid 29125113)
    • (1999) Journal of Investigative Dermatology , vol.112 , Issue.3 , pp. 354-361
    • Lucke, T.1    Choudhry, R.2    Thom, R.3    Selmer, I.-S.4    Burden, A.D.5    Hodgins, M.B.6
  • 128
    • 68249155826 scopus 로고
    • Altered [125i]epidermal growth factor binding and receptor distribution in psoriasis
    • Nanney LB, Stoscheck CM, Magid M, King LE Jr. Altered [125i]epidermal growth factor binding and receptor distribution in psoriasis. Biull Eksp Biol Med 1993; 115: 618-20.
    • (1993) Biull Eksp Biol Med , vol.115 , pp. 618-620
    • Nanney, L.B.1    Stoscheck, C.M.2    Magid, M.3    King Jr., L.E.4
  • 129
    • 0026087048 scopus 로고
    • Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis
    • Nickoloff BJ, Karabin GD, Barker JN, et al. Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis. Am J Pathol 1991; 138: 129-40.
    • (1991) Am J Pathol , vol.138 , pp. 129-140
    • Nickoloff, B.J.1    Karabin, G.D.2    Barker, J.N.3
  • 130
    • 0029834634 scopus 로고    scopus 로고
    • Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions
    • DOI 10.1083/jcb.135.1.227
    • Blessing M, Schirmacher P, Kaiser S. Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions. J Cell Biol 1996; 135: 227-39. (Pubitemid 26337750)
    • (1996) Journal of Cell Biology , vol.135 , Issue.1 , pp. 227-239
    • Blessing, M.1    Schirmacher, P.2    Kaiser, S.3
  • 131
    • 68249154274 scopus 로고    scopus 로고
    • The pathogenesis of psoriasis: Biochemical aspects
    • Grove T, Mulfinger L. The pathogenesis of psoriasis: biochemical aspects. J Young Invest 2001; 4.
    • (2001) J Young Invest , vol.4
    • Grove, T.1    Mulfinger, L.2
  • 134
    • 0029062615 scopus 로고
    • Discordant expression of Bcl-x and Bcl-2 by keratinocytes in vitro and psoriatic keratinocytes in vivo
    • Wrone-Smith T, Johnson T, Nelson B, et al. Discordant expression of Bcl-x and Bcl-2 by keratinocytes in vitro and psoriatic keratinocytes in vivo. Am J Pathol 1995; 146: 1079-88.
    • (1995) Am J Pathol , vol.146 , pp. 1079-1088
    • Wrone-Smith, T.1    Johnson, T.2    Nelson, B.3
  • 135
    • 0030712410 scopus 로고    scopus 로고
    • Expression of bcl-2 antagonist bak in inflammatory and neoplastic skin diseases
    • Tomkova H, Fujimoto W, Arata J. Expression of bcl-2 antagonist bak in inflammatory and neoplastic skin diseases. Br J Dermatol 1997; 137: 703-8. (Pubitemid 27496185)
    • (1997) British Journal of Dermatology , vol.137 , Issue.5 , pp. 703-708
    • Tomkova, H.1    Fujimoto, W.2    Arata, J.3
  • 136
    • 0031817363 scopus 로고    scopus 로고
    • Expression of the bcl-2 homologue bax in normal human skin, psoriasis vulgaris and non-melanoma skin cancers
    • Tomkova H, Fujimoto W, Arata J. Expression of the bcl-2 homologue Bax in normal human skin, psoriasis vulgaris and non-melanoma skin cancers. Eur J Dermatol 1998; 8: 256-60. (Pubitemid 28281453)
    • (1998) European Journal of Dermatology , vol.8 , Issue.4 , pp. 256-260
    • Tomkova, H.1    Fujimoto, W.2    Arata, J.3
  • 139
    • 33846906224 scopus 로고    scopus 로고
    • H17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • DOI 10.1038/nature05505, PII NATURE05505
    • Zheng Y, Danilenko DM, Valdez P, et al. Interleukin-22 a TH17 cytokine mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007; 445: 648-51. (Pubitemid 46232884)
    • (2007) Nature , vol.445 , Issue.7128 , pp. 648-651
    • Zheng, Y.1    Danilenko, D.M.2    Valdez, P.3    Kasman, I.4    Eastham-Anderson, J.5    Wu, J.6    Ouyang, W.7
  • 140
    • 0036385828 scopus 로고    scopus 로고
    • Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation
    • Chien AJ, Presland RB, Kuechle MK. Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation. Biochem Biophys Res Commun 2002; 296: 911-7.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 911-917
    • Chien, A.J.1    Presland, R.B.2    Kuechle, M.K.3
  • 143
    • 0038702528 scopus 로고    scopus 로고
    • Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies [1]
    • DOI 10.1038/sj.cdd.4401141
    • Lippens S, VandenBroecke C, Van Damme E, Tschachler E, Vandenabeele P, Declercq W. Caspase-14 is expressed in the epidermis the choroid plexus the retinal pigment epithelium and thymic Hassall's bodies. Cell Death Differ 2003; 10: 257-9. (Pubitemid 36553468)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.2 , pp. 257-259
    • Lippens, S.1    VandenBroecke, C.2    Van Damme, E.3    Tschachler, E.4    Vandenabeele, P.5    Declercq, W.6
  • 146
    • 58949094012 scopus 로고    scopus 로고
    • Maintained efficacy of the tyrosine kinase inhibitor imatinib mesylate in a patient with rheumatoid arthritis
    • Eklund KK, Lindstedt K, Sandler C, et al. Maintained efficacy of the tyrosine kinase inhibitor imatinib mesylate in a patient with rheumatoid arthritis. J Clin Rheumatol 2008; 14: 294-6.
    • (2008) J Clin Rheumatol , vol.14 , pp. 294-296
    • Eklund, K.K.1    Lindstedt, K.2    Sandler, C.3
  • 148
    • 0037032835 scopus 로고    scopus 로고
    • The protein kinase complement of the human genome
    • DOI 10.1126/science.1075762
    • Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science 2002; 298: 1912-34. (Pubitemid 35425239)
    • (2002) Science , vol.298 , Issue.5600 , pp. 1912-1934
    • Manning, G.1    Whyte, D.B.2    Martinez, R.3    Hunter, T.4    Sudarsanam, S.5
  • 149
    • 0034693799 scopus 로고    scopus 로고
    • The protein tyrosine kinase family of the human genome
    • Robinson DR, Wu YM, Lin SF. The protein tyrosine kinase family of the human genome. Oncogene 2000; 19: 55 48-57.
    • (2000) Oncogene , vol.19 , pp. 5548-5557
    • Robinson, D.R.1    Wu, Y.M.2    Lin, S.F.3
  • 150
    • 43749094998 scopus 로고    scopus 로고
    • The epidermal growth factor receptor system in skin repair and inflammation
    • DOI 10.1038/sj.jid.5701184, PII 5701184
    • Pastore S, Mascia F, Mariani V, Girolomoni G. The epidermal growth factor receptor system in skin repair and inflammation. J Invest Dermatol 2008; 128: 1365-74. (Pubitemid 351693180)
    • (2008) Journal of Investigative Dermatology , vol.128 , Issue.6 , pp. 1365-1374
    • Pastore, S.1    Mascia, F.2    Mariani, V.3    Girolomoni, G.4
  • 151
    • 22044442973 scopus 로고    scopus 로고
    • Tyrosine kinases as targets for cancer therapy
    • DOI 10.1056/NEJMra044389
    • Krause DS, Van Etten RA. Tyrosine kinases as targets for cancer therapy. N Engl J Med 2005; 353: 172-87. (Pubitemid 41058349)
    • (2005) New England Journal of Medicine , vol.353 , Issue.2 , pp. 172-187
    • Krause, D.S.1    Van Etten, R.A.2
  • 152
    • 0033786922 scopus 로고    scopus 로고
    • Protein tyrosine kinase structure and function
    • Hubbard SR, Till JH. Protein tyrosine kinase structure and function. Annu Rev Biochem 2000; 69: 373-98.
    • (2000) Annu Rev Biochem , vol.69 , pp. 373-398
    • Hubbard, S.R.1    Till, J.H.2
  • 153
    • 62849094732 scopus 로고    scopus 로고
    • Selectivity and therapeutic inhibition of kinases to be or not to be
    • Ghoreschi K, Laurence A, O'Shea JJ. Selectivity and therapeutic inhibition of kinases to be or not to be. Nat Immunol 2009; 10: 356-60.
    • (2009) Nat Immunol , vol.10 , pp. 356-360
    • Ghoreschi, K.1    Laurence, A.2    O'Shea, J.J.3
  • 155
    • 0036038079 scopus 로고    scopus 로고
    • Psoriasis is mediated by a cutaneous defect triggered by activated immunocytes: Induction of psoriasis by cells with natural killer receptors
    • DOI 10.1046/j.1523-1747.2002.01812.x
    • Gilhar A, Ullmann Y, Kerner H, et al. Psoriasis is mediated by a cutaneous defect triggered by activated immunocytes induction of psoriasis by cells with natural killer receptors. J Invest Dermatol 2002; 119: 384-91. (Pubitemid 35001948)
    • (2002) Journal of Investigative Dermatology , vol.119 , Issue.2 , pp. 384-391
    • Gilhar, A.1    Ullmann, Y.2    Kerner, H.3    Assy, B.4    Shalaginov, R.5    Serafimovich, S.6    Kalish, R.S.7
  • 156
    • 0029030963 scopus 로고
    • Potent antagonism of calmodulin activity in vitro, but lack of antiproliferative effects on keratinocytes by the novel leukotriene biosynthesis inhibitor MK-886
    • Hegemann L, Hatzelmann A, Grewig S, Schmidt BH. Potent antagonism of calmodulin activity in vitro, but lack of antiproliferative effects on keratinocytes by the novel leukotriene biosynthesis inhibitor MK-886. Br J Dermatol1995; 133: 41-7.
    • (1995) Br J Dermatol , vol.133 , pp. 41-47
    • Hegemann, L.1    Hatzelmann, A.2    Grewig, S.3    Schmidt, B.H.4
  • 157
  • 163
    • 0031955175 scopus 로고    scopus 로고
    • Psoriatic keratinocytes express high levels of nerve growth factor
    • DOI 10.1080/000155598433368
    • Raychaudhuri SP, Jiang WY, Farber EM. Psoriatic keratinocytes express high levels of nerve growth factor. Acta Derm Venereol 1998; 78: 84-6. (Pubitemid 28153332)
    • (1998) Acta Dermato-Venereologica , vol.78 , Issue.2 , pp. 84-86
    • Raychaudhuri, S.P.1    Jiang, W.-Y.2    Farber, E.M.3
  • 166
    • 0016029730 scopus 로고
    • Natural history of psoriasis in 61 twin pairs
    • Farber EM, Nall L, Watson W. Natural history of psoriasis in 61 twin pairs. Arch Dermatol 1974; 109: 207-11.
    • (1974) Arch Dermatol , vol.109 , pp. 207-211
    • Farber, E.M.1    Nall, L.2    Watson, W.3
  • 167
    • 0020051265 scopus 로고
    • Psoriasis in monozygotic twins variations in expression in individuals with identical genetic constitution
    • Brandrup F, Holm N, Grunnet N, Henningsen K, Hansen HE. Psoriasis in monozygotic twins variations in expression in individuals with identical genetic constitution. Acta Dermatol 1982; 62: 229- 36.
    • (1982) Acta Dermatol , vol.62 , pp. 229-236
    • Brandrup, F.1    Holm, N.2    Grunnet, N.3    Henningsen, K.4    Hansen, H.E.5
  • 168
    • 0021806161 scopus 로고
    • Psoriasis of early and late onset: Characterization of two types of psoriasis vulgaris
    • Henseler T, Christophers E. Psoriasis of early and late onset characterization of two types of psoriasis vulgaris. J Am Acad Dermatol 1985; 13(3): 450-6. (Pubitemid 15016489)
    • (1985) Journal of the American Academy of Dermatology , vol.13 , Issue.3 , pp. 450-456
    • Henseler, T.1    Christophers, E.2
  • 171
    • 0025373181 scopus 로고
    • HLA region genes and immune activation in the pathogenesis of psoriasis
    • DOI 10.1001/archderm.126.8.1083
    • Gottlieb AB, Krueger JG. HLA region genes and immune activation in the pathogenesis of psoriasis. Arch Dermatol 1990; 126: 1083-6. (Pubitemid 20233186)
    • (1990) Archives of Dermatology , vol.126 , Issue.8 , pp. 1083-1086
    • Gottlieb, A.B.1    Krueger, J.G.2
  • 178
    • 0032900956 scopus 로고    scopus 로고
    • Searching for psoriasis susceptibility genes in Italy Genome scan and evidence for a new locus on chromosome 1
    • Capon F, Novelli G, Semprini S, et al. Searching for psoriasis susceptibility genes in Italy Genome scan and evidence for a new locus on chromosome 1. J Invest Dermatol 1999; 112: 52-5.
    • (1999) J Invest Dermatol , vol.112 , pp. 52-55
    • Capon, F.1    Novelli, G.2    Semprini, S.3
  • 180
    • 0033010024 scopus 로고    scopus 로고
    • Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families: Confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q
    • DOI 10.1159/000022832
    • Enlund F, Samuelsson L, Enerback C, et al. Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families confirmation of linkage to chromosome 6p (HLA region) and to 17q, but not to 4q. Hum Hered 1999; 49: 2-8. (Pubitemid 29050288)
    • (1999) Human Heredity , vol.49 , Issue.1 , pp. 2-8
    • Enlund, F.1    Samuelsson, L.2    Enerback, C.3    Inerot, A.4    Wahlstrom, J.5    Yhr, M.6    Torinsson, A.7    Martinsson, T.8    Swanbeck, G.9
  • 184
    • 0033795055 scopus 로고    scopus 로고
    • Genome wide scan in German families reveals evidence for a novel psoriasissusceptibility locus on chromosome 19p13
    • Lee YA, Roschendorf F, Windemuth C, et al. Genome wide scan in German families reveals evidence for a novel psoriasissusceptibility locus on chromosome 19p13. Am J Hum Genet 2000; 67: 1020-4.
    • (2000) Am J Hum Genet , vol.67 , pp. 1020-1024
    • Lee, Y.A.1    Roschendorf, F.2    Windemuth, C.3
  • 185
    • 34547790677 scopus 로고    scopus 로고
    • Interplay among oxidants, antioxidants, and cytokines in skin disorders: Present status and future considerations
    • DOI 10.1016/j.biopha.2007.05.010, PII S075333220700114X
    • Portugal M, Barak V, Ginsburg I, Kohen R. Interplay among oxidants, antioxidants, and cytokines in skin disorders present status and future considerations. Biomed Pharmacother 2007; 61: 412-22. (Pubitemid 47239346)
    • (2007) Biomedicine and Pharmacotherapy , vol.61 , Issue.7 , pp. 412-422
    • Portugal, M.1    Barak, V.2    Ginsburg, I.3    Kohen, R.4
  • 186
    • 70449718874 scopus 로고    scopus 로고
    • Current Treatment of Psoriasis with Biologics
    • Kunz, Manfred. Current Treatment of Psoriasis with Biologics. Curr Drug Discov Technol 2009; 6: 231-40.
    • (2009) Curr Drug Discov Technol , vol.6 , pp. 231-240
    • Kunz, M.1
  • 187
    • 0029053451 scopus 로고
    • Superoxide radical and superoxide dismutases
    • Fridovich I. Superoxide radical and superoxide dismutases. Annu Rev Biochem1995; 64: 97-112.
    • (1995) Annu Rev Biochem , vol.64 , pp. 97-112
    • Fridovich, I.1
  • 190
    • 0033230807 scopus 로고    scopus 로고
    • Tissue-specific functions of individual glutathione peroxidases
    • DOI 10.1016/S0891-5849(99)00173-2, PII S0891584999001732
    • Brigelius-Flohe R. Tissue-specific functions of individual glutathione peroxidases. Free Radic Biol Med 1999; 27: 951-65. (Pubitemid 29507469)
    • (1999) Free Radical Biology and Medicine , vol.27 , Issue.9-10 , pp. 951-965
    • Brigelius-Flohe, R.1
  • 191
    • 0033775891 scopus 로고    scopus 로고
    • Physiological functions of thioredoxin and thioredoxin reductase
    • Arner ES, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem 2000; 267: 6102-9.
    • (2000) Eur J Biochem , vol.267 , pp. 6102-6109
    • Arner, E.S.1    Holmgren, A.2
  • 193
    • 0001776198 scopus 로고    scopus 로고
    • DAB (389) IL-2 (denileukin diftitox, ONTAK) a new fusion protein technology
    • Foss FM. DAB (389) IL-2 (denileukin diftitox, ONTAK) a new fusion protein technology. Clin Lymphoma 2000; 1(Suppl. 1): S27-31.
    • (2000) Clin Lymphoma , vol.1 , Issue.SUPPL. 1
    • Foss, F.M.1
  • 195
    • 0033749344 scopus 로고    scopus 로고
    • Successful treatment of severe generalized pustular psoriasis with basiliximab (interleukin-2 receptor blocker)
    • Salim A, Emerson RM, Dalziel KL. Successful treatment of severe generalized pustular psoriasis with basiliximab (interleukin-2 receptor blocker). Br J Dermatol 2000; 143: 1121-2.
    • (2000) Br J Dermatol , vol.143 , pp. 1121-1122
    • Salim, A.1    Emerson, R.M.2    Dalziel, K.L.3
  • 196
    • 0034074077 scopus 로고    scopus 로고
    • Successful treatment of severe psoriasis with basiliximab, an interleukin-2 receptor monoclonal antibody
    • DOI 10.1046/j.1365-2230.2000.00612.x
    • Owen CM, Harrison PV. Successful treatment of severe psoriasis with basiliximab, an interleukin-2 receptor monoclonal antibody. Clin Exp Dermatol 2000; 25: 195-7. (Pubitemid 30340544)
    • (2000) Clinical and Experimental Dermatology , vol.25 , Issue.3 , pp. 195-197
    • Owen, C.M.1    Harrison, P.V.2
  • 199
    • 0037592156 scopus 로고    scopus 로고
    • Clinical response to alefacept results of a phase 3 study of intravenous administration of alefacept in patients with chronic plaque psoriasis
    • Krueger G. Clinical response to alefacept results of a phase 3 study of intravenous administration of alefacept in patients with chronic plaque psoriasis. J Eur Acad Dermatol Venereol 2003; 17(Suppl. 2): 17-24.
    • (2003) J Eur Acad Dermatol Venereol , vol.17 , Issue.SUPPL. 2 , pp. 17-24
    • Krueger, G.1
  • 200
    • 0000033485 scopus 로고    scopus 로고
    • Phase I results of intravenous MEDI-507 an anti-T-cell antibody for the treatment of psoriasis
    • Langley R, Roenigk H, McCall C. Phase I results of intravenous MEDI-507 an anti-T-cell antibody for the treatment of psoriasis. J Invest Dermatol 2001; 117: 817.
    • (2001) J Invest Dermatol , vol.117 , pp. 817
    • Langley, R.1    Roenigk, H.2    McCall, C.3
  • 201
    • 0036792808 scopus 로고    scopus 로고
    • Clinical and immunologic assessment of patients with psoriasis in a randomized double-blind placebo-controlled trial using recombinant human interleukin -10
    • Kimball AB, Kawamura T, Tejura K, et al. Clinical and immunologic assessment of patients with psoriasis in a randomized double-blind placebo-controlled trial using recombinant human interleukin -10. Arch Dermatol 2002; 138: 1341-6.
    • (2002) Arch Dermatol , vol.138 , pp. 1341-1346
    • Kimball, A.B.1    Kawamura, T.2    Tejura, K.3
  • 202
    • 4444255889 scopus 로고    scopus 로고
    • Adalimumab efficacy and safety in patients with moderate to severe chronic plaque psoriasis preliminary findings from a 12 week dose ranging trial
    • Chen DM, Gordon K, Leonardi C, et al. Adalimumab efficacy and safety in patients with moderate to severe chronic plaque psoriasis preliminary findings from a 12 week dose ranging trial. J Am Acad Dermatol 2004; 50(Pt II): PS 491.
    • (2004) J Am Acad Dermatol , vol.50 , Issue.PART II
    • Chen, D.M.1    Gordon, K.2    Leonardi, C.3
  • 203
    • 0030587817 scopus 로고    scopus 로고
    • Recombinant Human IL-11 Attenuates the Inflammatory Response Through Down-Regulation of Proinflammatory Cytokine Release and Nitric Oxide Production
    • Trepicchio WL, Bozza M, Pedneault G, Dorner AJ. Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production. J Immunol 1996; 157: 3627-34. (Pubitemid 126449177)
    • (1996) Journal of Immunology , vol.157 , Issue.8 , pp. 3627-3634
    • Trepicchio, W.L.1    Bozza, M.2    Pedneault, G.3    Dorner, A.J.4
  • 206
    • 84858170147 scopus 로고    scopus 로고
    • Abgenix discontinues treatment after disappointing psoriasis study results
    • Zhou X, Krueger JG, Kao MC. Abgenix discontinues treatment after disappointing psoriasis study results. East Bay Business Times 2002.
    • (2002) East Bay Business Times
    • Zhou, X.1    Krueger, J.G.2    Kao, M.C.3
  • 207
    • 74249094930 scopus 로고    scopus 로고
    • Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis
    • Griffiths CE, Strober BE, Van De Kerkhof P, et al. Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis. N Engl J Med 2010; 362: 118-28.
    • (2010) N Engl J Med , vol.362 , pp. 118-128
    • Griffiths, C.E.1    Strober, B.E.2    Van De Kerkhof, P.3
  • 208
    • 39649108216 scopus 로고    scopus 로고
    • Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: Results of a randomized, placebo-controlled, phase 2 trial
    • DOI 10.1001/archdermatol.2007.63
    • Kimball AB, Gordon KB, Langley RG, Menter A, Chartash EK, Valdes J. Safety and efficacy of ABT- 874, a fully human interleukin 12/23 monoclonal antibody in the treatment of moderate to severe chronic plaque psoriasis results of a randomized placebo-controlled phase 2 trials. Arch Dermatol 2008; 144: 200-7. (Pubitemid 351287002)
    • (2008) Archives of Dermatology , vol.144 , Issue.2 , pp. 200-207
    • Kimball, A.B.1    Gordon, K.B.2    Langley, R.G.3    Menter, A.4    Chartash, E.K.5    Valdes, J.6
  • 210
    • 51349142546 scopus 로고    scopus 로고
    • Ethyl pyruvate has an anti-inflammatory effect by inhibiting ROS-dependent STAT signaling in activated microglia
    • Kim HS, Cho IH, Kim JE, Shin, et al. Ethyl pyruvate has an anti-inflammatory effect by inhibiting ROS-dependent STAT signaling in activated microglia. Free Radic Biol Med 2008; 45: 950-63.
    • (2008) Free Radic Biol Med , vol.45 , pp. 950-963
    • Kim, H.S.1    Cho, I.H.2    Kim, J.E.3    Shin4
  • 214
    • 20944436301 scopus 로고    scopus 로고
    • Antagonism of epidermal growth factor receptor tyrosine kinase ameliorates the psoriatic phenotype in organ-cultured skin
    • DOI 10.1159/000084909
    • Varani J, Lateef H, Fay K, Elder JT. Antagonism of epidermal growth factor receptor tyrosine kinase ameliorates the psoriatic phenotype in organ-cultured skin. Skin Pharmacol Physiol 2005; 18: 123-31. (Pubitemid 40868668)
    • (2005) Skin Pharmacology and Physiology , vol.18 , Issue.3 , pp. 123-131
    • Varani, J.1    Lateef, H.2    Fay, K.3    Elder, J.T.4
  • 215
    • 33847020465 scopus 로고    scopus 로고
    • SU-011248, a vascular endothelial growth factor receptor-tyrosine kinase inhibitor, controls chronic psoriasis
    • DOI 10.1016/j.trsl.2007.01.003, PII S1931524407000333
    • Keshtgarpour M, Dudek AZ. SU-011248 a vascular endothelial growth factor receptor-tyrosine kinase inhibitor controls chronic psoriasis. Transl Res 2007; 149: 103-6. (Pubitemid 46275576)
    • (2007) Translational Research , vol.149 , Issue.3 , pp. 103-106
    • Keshtgarpour, M.1    Dudek, A.Z.2
  • 218
    • 0036379590 scopus 로고    scopus 로고
    • Improvement of psoriasis during imatinib therapy in a patient with a metastatic gastrointestinal stromal tumor
    • Miyagawa S, Fujimoto H, Ko S, Hirota S, Kitamura Y. Improvement of psoriasis during imatinib therapy in a patient with a metastatic gastrointestinal stromal tumor. Br J Dermatol 2002; 147: 406-7.
    • (2002) Br J Dermatol , vol.147 , pp. 406-407
    • Miyagawa, S.1    Fujimoto, H.2    Ko, S.3    Hirota, S.4    Kitamura, Y.5
  • 219
    • 51149117030 scopus 로고    scopus 로고
    • Drug insight intracellular inhibitors of HER2 clinical development of lapatinib in breast cancer
    • Cameron D, Stein S. Drug insight intracellular inhibitors of HER2 clinical development of lapatinib in breast cancer. Nat Clin Pract Oncol 2008; 5: 512-20
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 512-520
    • Cameron, D.1    Stein, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.