NADPH oxidase(s): New source(s) of reactive oxygen species in the vascular system?

Journal of Clinical Pathology

Volumn 55, Issue 8, 2002, Pages 561-568

  Van Heerebeek, L ^a   Meischl, C ^b   Stooker, W ^a   Meijer, C J L M ^a   Niessen, H W M ^a   Roos, D ^b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; BLOOD CLOTTING FACTOR; CYTOKINE; DNA; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ADVENTITIA; ATHEROSCLEROSIS; BLOOD CLOTTING; BLOOD VESSEL; CARDIOVASCULAR SYSTEM; CELL TYPE; DNA SEQUENCE; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME SUBUNIT; FIBROBLAST; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEUKOCYTE FUNCTION; MECHANICAL STRESS; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; VASCULAR SMOOTH MUSCLE;

ANIMALS; BLOOD VESSELS; HUMANS; MUSCLE, SMOOTH, VASCULAR; NADH, NADPH OXIDOREDUCTASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 0036345585     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.55.8.561     Document Type: Review

References (71)

1. NAD(P)H oxidase: Role in cardiovascular biology and disease
2. Superoxide forming NADPH oxidase of phagocytes: An enzyme system regulated by multiple mechanisms
3. Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease
4. Neutrophil signal transduction and activation of the respiratory burst
5. Disturbed interaction of p21-rac with mutated p67phox causes chronic granulomatous disease
6. Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase
7. Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558
8. Chronic granulomatous disease
9. 558 molecules involved in the fibroblast and polymorphonuclear leucocyte superoxide-generating NADPH oxidase systems are structurally and genetically distinct
10. 2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase
11. 558 in patients with cytochrome b positive and negative X-linked chronic granulomatous disease
12. Molecular characterization and localization of the NAD(P)H oxidase components gp91 phox and p22phox in endothelial cells
13. Expression of functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells
14. NADPH oxidase subunits and superoxide production in porcine pulmonary artery endothelial cells
15. 558 alpha subunit cloning and expression in rat aortic smooth muscle cells
16. Oxidative stress and expression of p22phox are involved in the up-regulation of tissue factor in vascular smooth muscle cells in response to activated platelets
17. p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II induced hypertrophy in vascular smooth muscle cells
18. Superoxide anion from the adventitia of the rat thoracic aorta inactivates nitric oxide
19. Localization of a constitutively active, phagocyte like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II
20. Pulmonary artery NADPH oxidase is activated in hypoxic pulmonary vasoconstriction
21. Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+
22. Angiotensin II induces p67phox mRNA expression and NADPH oxidase superoxide generation in rabbit aortic adventitial fibroblasts
23. Components in human endothelial cells
24. A gp91 phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
25. Identification of a functional leukocyte type NADPH oxidase in human endothelial cells: A potential atherogenic source of reactive oxygen species
26. Expression of NADH/NADPH oxidase p22phox in human coronary arteries
27. NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells
28. Role of the vascular NADH/NADPH oxidase system in atherosclerosis
29. Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin: Evidence that p47phox may participate in forming this oxidase in vitro and in vivo
30. Cell transformation by the superoxide generating oxidase Mox1
31. NADPH oxidase subunit, gp91phox homologue, preferentially expressed in human colon epithelial cells
32. Identification of Renox, an NAPDH oxidase in kidney
33. A novel superoxide-producing NAD(P)H oxidase in kidney
34. Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family
35. The influence of phorbol myristate acetate on oxygen consumption of peripheral blood leukocytes
36. Simulated ischemia in flow-adapted endothelial cells leads to generation of reactive oxygen species and cell signalling
37. Tumour necrosis factor alpha activates a p22phox based NADH oxidase in vascular smooth muscle
38. Role of increased production of superoxide anions by NAD(P)H oxidase and xanthine oxldase in prolonged endotoxemia
39. Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: Involvement of p22phox and reactive oxygen species
40. 2 in angiotensin II induced vascular hypertrophy
41. Gene transfer of endothelial nitric oxide synthase reduces angiotensin II-induced endothelial dysfunction
42. Paracrine role of adventitial superoxide anion in mediating spontaneous tone of the isolated rat aorta in angiotensin II-induced hypertension
43. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
44. Endothelial cell oxidant production: Effect of NADPH oxidase inhibitors
45. Pulsatile stretch stimulates superoxide production in human aortic endothelial cells
46. Pulsatile stretch stimulates superoxide production and activates nuclear factor-kappa B in human coronary smooth muscle
47. Antioxidants inhibit monocyte adhesion by suppressing nuclear factor kappa B mobilization and induction of vascular cell adhesion molecule 1 in endothelial cells stimulated to generate radicals
48. Lactosylceramide mediates tumor necrosis factor alpha induced intercellular adhesion molecule 1 (ICAM-1) expression and the adhesion of neutrophils in human umbilical vein endothelial cells
49. Endothelin-1 induces NAD(P)H oxidase in human endothelial cells
50. Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-kappaB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cells
51. Effect of NADPH oxidase inhibition on endothelial cell ELAM-1 mRNA expression
52. Role of reactive oxygen species in bradykinin-induced mitogen activated protein kinase and c-fos induction in vascular cells
53. Angiotensin II induced superoxide anion generation in human vascular endothelial cells: Role of membrane bound NADH/NADPH oxidases
54. Thrombin stimulated reactive oxygen species production in cultured human endothelial cells
55. Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats
56. p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats
57. Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice
58. Vascular effect following homozygous disruption of p47phox: An essential component of NADPH oxidase
59. 558 light chain of the NADPH oxidase (p22phox)
60. A variant of p22phox, involved in generation of reactive oxygen species in the vessel wall, is associated with progression of coronary atherosclerosis
61. 242T polymorphism and coronary artery disease in the Australian population
62. Polymorphism of the NADH/NADPH oxidase p22phox gene in patients with coronary artery disease
63. 242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function
64. The p22phox polymorphism C242T is not associated with CHD risk in Asian Indians and Chinese
65. The p22phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals
66. 242T polymorphism of NADPH oxidase p22phox gene and ischemic cerebrovascular disease in the Japanese population
67. Sphingolipids in atherosclerosis and vascular biology
68. Lactosylceramlde stimulates human neutrophils to upregulate Mac-1, adhere to endothelium, and generate reactive oxygen metabolites in vitro
69. Endothelin-1 and smooth muscle cells: Induction of Jun amino terminal kinase through an oxygen radical sensitive mechanism
70. Redox-regulated signaling by lactosylceramide in the proliferation of human aortic smooth muscle cells
71. Coronary microvascular endothelial cell redox state in left ventricular hypertrophy: The role of angiotensin II