Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium

Journal of Investigative Dermatology

Volumn 112, Issue 3, 1999, Pages 354-361

  Lucke, Tom ^a   Choudhry, Rukhsana ^a   Thom, Russell ^a   Selmer, Inger Sofie ^a   Burden, A David ^a   Hodgins, Malcolm B ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Connexin; Gap junctions; Ki67; Psoriasis

Indexed keywords

CONNEXIN 26; GAP JUNCTION PROTEIN; KI 67 ANTIGEN;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHEEK MUCOSA; CONTROLLED STUDY; EPIDERMIS CELL; GAP JUNCTION; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PSORIASIS; VAGINA EPITHELIUM;

EID: 0033024635     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1999.00512.x     Document Type: Article

References (30)

1. Bergoffen J, Scherer SS, Wang S, et al: Connexin mutations in X-linked Charcot-Marie-Tooth disease. Science 262:2039-2042, 1993
2. Brissette JL, Kumar NM, Gilula NB, Hall JE, Dotto GP: Switch in gap junction protein expression is associated with selective changes in junctional permeability during keratinocyte differentiation. Proc Natl Acad Sci USA 91:6453-6457, 1994
3. Britz-Cunningham SH, Shah MM, Zuppan CW, Fletcher WH: Mutations in the connexin 43 gap-junction gene in patients with heart malformations and defects of laterality. N Engl J Med 332:1323-1329, 1995
4. Bruzzone R, White TW, Goodenough DA: The cellular internet: on-line with connexins. Bio Essays 18:709-718, 1996
5. Budunova IV, Carbajal S, Slaga TI: The expression of gap junctional proteins during different stages of mouse skin carcinogenesis. Carcinogenesis 16:2717-2724, 1995
6. Butterwecke A, Elfgang C, Willecke K, Traub O: Differential expression of gap junction proteins connexin 45, -43, -40, -31, and -26 in mouse skin. Eur J Cell Biol 65:152-163, 1994
7. Caputo R, Innocenti M, Gasparini G, Peluchetti D: Plasma membranes in psoriatic cells. A freeze-fracture study. J Invest Dermatol 71:245-249, 1978
8. Cavicchini S, Brezzi A, Gasparini G, Caputo R: Skin ultrastructure after calcipotrioltreatment: a transmission electron microscopic and freeze-fracture study on psoriatic patients. Acta Derm Venereol 76:186-189, 1996
9. Choudhry R, Pitts JD, Hodgins MB: Changing patterns of gap junctional intercellular communication and connexin distribution in mouse epidermis and hair follicles during embryonic development. Dev Dynamics 210:417-430, 1997
10. Dahl E, Winterhager E, Reu B, Traub O, Butterweck A,. Willecke K: Expression of gap junction proteins connexin 31 and connexin 43 correlates with communication compartments in extraembryonic tissues and in the gastrulating mouse embryo respectively. J Cell Sci 109:191-197, 1996a
11. Dahl E, Manthey D, Chen Y, et al: Molecular cloning and functional expression of mouse connexin 30, a gap junction gene highly expressed in brain and skin. J Biol Chem 271:17903-17910, 1996b
12. Gerdes J, Lemke H, Baisch H: Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 133:1710-1715, 1984
13. Goliger J, Paul D: Expression of gap junction proteins Cx26, Cx31.1, Cx37 and Cx43 in developing and mature rat epidermis. Dev Dynamics 200:1-13, 1994
14. Goliger JA, Paul DL: Wounding alters epidermal connexin expression and gap junction-mediated intercellular communication. Mol Biol Cell 6:1491-1501, 1995
15. Green CR: Evidence mounts for the role of gap junctions during development. Bio Essays 8:7-10, 1988
16. Guo H, Acevedo P, Parsa D, Bertram J: Gap-junctional protein connexin 43 is expressed in dermis and epidermis of human skin: differential modulation by retinoids. J Invest Dermatol 99:460-467, 1992
17. Kamibayashi Y, Oyamada M, Oyamada Y, Mori M: Expression of gap junction proteins Cx26 and Cx43 is modulated during differentiation of keratinocytes in newborn mouse epidermis. J Invest Dermatol 101:773-778, 1993
18. Kelsell DP, Dunlop J, Stevens HP, et al: Connexin 26 mutations in hereditary non-syndromic sensorineural deafness. Nature 387:80-83, 1997
19. Krutovskikh V, Yamasaki H: The role of gap junctional intercellular communication (GJIC) disorders in experimental and human carcinogenesis. Histol Histopathol 12:761-768, 1997
20. Labarthe MP, Bosco D, Saurat JH, Meda P, Salomon D: Upregulation of connexin 26 between keratinocytes of psoriatic lesions. J Invest Dermatol 111:72-76, 1998
21. Masgrau-Peya E, Salomon D, Saurat JH, Meda P: In vivo modulation of connexins 43 and 26 of human epidermis by topical retinoic acid treatment. J Histochem Cytochem 45:1207-1215, 1997
22. Mesnil M, Piccoli C, Yamasaki H: A tumour suppressor gene, Cx26, also mediates the bystander effect in HeLa cells. Cancer Res 57:2929-2932, 1997
23. Risek B, Klier FG, Gilula NB: Developmental regulation and structural organisation of connexins in epidermal gap junctions. Dev Biol 164:183-196, 1994
24. Risek B, Pozzi A, Gilula NB: Modulation of gap junction expression during transient hyperplasia of rat epidermis. J Cell Sci 111:1395-1404, 1998
25. Rivas M, Jarvis E, Morisaki S, Carbonaro H, Gottlieb A, Krueger J: Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique. J Invest Dermatol 108:188-194, 1997
26. Salomon D, Saurat JH, Meda P: Cell-to-cell communication within intact human skin. J Clin Invest 82:248-254, 1988
27. Salomon D, Masgrau E, Vischer S, et al: Topography of mammalian connexins in human skin. J Invest Dermatol 103:240-247, 1994
28. Veenstra RD: Size and selectivity of gap junction channels formed from different connexins. J Bioenerget Biomembr 28:327-337, 1996
29. Wilgenbus KK, Kirkpatrick CJ, Knuechel R, Willecke K, Traub O: Expression of Cx26, Cx32 and Cx43 gap junction proteins in normal and neoplastic human tissues. Int J Cancer 51:522-529, 1992
30. Zelante L, Gasparini P, Estivill X, et al: Connexin 26 mutations associated with the most common form of non-syndromic neurosensory autosomal recessive deafness (DFNB1) in Mediterraneans. Hum Mol Genet 6:1605-1609, 1997