FADD cleavage by NK cell granzyme M enhances its self-association to facilitate procaspase-8 recruitment for auto-processing leading to caspase cascade

Cell Death and Differentiation

Volumn 19, Issue 4, 2012, Pages 605-615

  Wang, S ^a   Xia, P ^a   Shi, L ^a   Fan, Z ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

casp cascade; casp 8; FADD; granzyme M; proteolysis

Indexed keywords

CASPASE 8; CYTOCHROME C; DEATH RECEPTOR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GRANZYME; GRANZYME M; LYMPHOKINE; PROCASPASE 3; PROCASPASE 8; PROTEIN BID; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NATURAL KILLER CELL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN SECRETION;

APOPTOSIS; CASPASE 8; ENZYME ACTIVATION; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GENE KNOCKDOWN TECHNIQUES; GRANZYMES; HELA CELLS; HUMANS; JURKAT CELLS; KILLER CELLS, NATURAL; PROTEIN MULTIMERIZATION; PROTEOLYSIS;

EID: 84858158784     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.130     Document Type: Article

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