Impaired redox signaling and mitochondrial uncoupling contributes vascular inflammation and cardiac dysfunction in type 1 diabetes: Protective role of arjunolic acid

Biochimie

Volumn 94, Issue 3, 2012, Pages 786-797

  Manna, Prasenjit ^a   Sil, Parames C ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Antioxidant and antidiabetic; Arjunolic acid; Cardiac dysfunction and apoptosis; Hyperglycemia; Reactive intermediates; Vascular inflammation

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ADENOSINE TRIPHOSPHATE; ARJUNOLIC ACID; CARDIOVASCULAR AGENT; CASPASE 3; CATALASE; CHOLESTEROL; CREATINE KINASE; CYTOCHROME C; GLUCOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; TRITERPENOID; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE; CONTROLLED STUDY; DIABETIC ANGIOPATHY; DIABETIC CARDIOMYOPATHY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME RELEASE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GLUCOSE BLOOD LEVEL; HISTOLOGY; HYPERGLYCEMIA; HYPERLIPIDEMIA; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; LIPID PEROXIDATION; MALE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PROTEIN CARBONYLATION; PROTEIN CLEAVAGE; RAT; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; VASCULITIS; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CHEMOKINE CCL2; CYTOCHROMES C; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; FLOW CYTOMETRY; HYPOGLYCEMIC AGENTS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MALE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRITERPENES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA; RATTUS;

EID: 84857056966     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2011.11.010     Document Type: Article

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