Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: Activation of polyol pathway and oxidative stress responsive signaling cascades

Chemico-Biological Interactions

Volumn 181, Issue 3, 2009, Pages 297-308

  Manna, Prasenjit ^a   Sinha, Mahua ^a   Sil, Parames C ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Arjunolic acid; Hyperglycemia; Mitochondrial damage; Renal dysfunction; Renal protection; Streptozotocin

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALDEHYDE REDUCTASE; ANTIOXIDANT; ARJUNOLIC ACID; CASPASE 3; CREATININE; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE; POLYOL; PROTEIN BCL 2; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SAPONIN; STREPTOZOCIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; HYPERGLYCEMIA; KIDNEY DYSFUNCTION; KIDNEY FAILURE; KIDNEY INJURY; KIDNEY MASS; KIDNEY PARENCHYMA; LIPID PEROXIDATION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN CARBONYLATION; RAT; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; UREA NITROGEN BLOOD LEVEL;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; DIABETIC NEPHROPATHIES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; MALE; NITRIC OXIDE; OXIDATIVE STRESS; POLYMERS; PROTEIN KINASES; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STREPTOZOCIN; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; RATTUS;

EID: 70349172654     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.08.004     Document Type: Article

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