Oral insulin treatment suppresses virus-induced antigen-specific destruction of β cells and prevents autoimmune diabetes in transgenic mice

Journal of Clinical Investigation

Volumn 98, Issue 6, 1996, Pages 1324-1331

  Von Herrath, Matthias G ^a   Dyrberg, Thomas ^b   Oldstone, Michael B A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NOVO NORDISK A S   (Denmark)

Author keywords

bystander suppression; insulin; insulin dependent diabetes mellitus; lymphocytic choriomeningitis virus; oral tolerance

Indexed keywords

INSULIN; VIRUS NUCLEOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DIABETES MELLITUS; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR UPREGULATION; TRANSGENIC MOUSE; VIRUS INDUCTION;

EID: 0029744298     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118919     Document Type: Article

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