메뉴 건너뛰기




Volumn 131, Issue 2, 2011, Pages 382-390

Skin commensals amplify the innate immune response to pathogens by activation of distinct signaling pathways

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN 1; BETA DEFENSIN 2; BETA DEFENSIN 3; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RIBONUCLEASE; RIBONUCLEASE 7; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG;

EID: 78651383015     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2010.328     Document Type: Article
Times cited : (217)

References (37)
  • 1
    • 14544282377 scopus 로고    scopus 로고
    • Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?
    • Brogden KA (2005) Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol 3:238-50
    • (2005) Nat Rev Microbiol , vol.3 , pp. 238-250
    • Brogden, K.A.1
  • 2
    • 26844567701 scopus 로고    scopus 로고
    • Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli
    • Chen X, Niyonsaba F, Ushio H et al. (2005) Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli. J Dermatol Sci 40:123-32
    • (2005) J Dermatol Sci , vol.40 , pp. 123-132
    • Chen, X.1    Niyonsaba, F.2    Ushio, H.3
  • 3
    • 0346881404 scopus 로고    scopus 로고
    • Innate immune response of oral and foreskin keratinocytes: Utilization of different signaling pathways by various bacterial species
    • Chung WO, Dale BA (2004) Innate immune response of oral and foreskin keratinocytes: utilization of different signaling pathways by various bacterial species. Infect Immun 72:352-8
    • (2004) Infect Immun , vol.72 , pp. 352-358
    • Chung, W.O.1    Dale, B.A.2
  • 4
    • 39049154328 scopus 로고    scopus 로고
    • Skin microbiota: A source of disease or defence?
    • Cogen AL, Nizet V, Gallo RL (2008) Skin microbiota: a source of disease or defence? Br J Dermatol 158:442-55
    • (2008) Br J Dermatol , vol.158 , pp. 442-455
    • Cogen, A.L.1    Nizet, V.2    Gallo, R.L.3
  • 5
    • 0037250369 scopus 로고    scopus 로고
    • Keratinocyte expression of human beta defensin 2 following bacterial infection: Role in cutaneous host defense
    • Dinulos JG, Mentele L, Fredericks LP et al. (2003) Keratinocyte expression of human beta defensin 2 following bacterial infection: role in cutaneous host defense. Clin Diagn Lab Immunol 10:161-6
    • (2003) Clin Diagn Lab Immunol , vol.10 , pp. 161-166
    • Dinulos, J.G.1    Mentele, L.2    Fredericks, L.P.3
  • 6
    • 0031456095 scopus 로고    scopus 로고
    • The expression and modulation of IFN-alpha and IFN-beta in human keratinocytes
    • Fujisawa H, Kondo S, Wang B et al. (1997) The expression and modulation of IFN-alpha and IFN-beta in human keratinocytes. J Interferon Cytokine Res 17:721-5
    • (1997) J Interferon Cytokine Res , vol.17 , pp. 721-725
    • Fujisawa, H.1    Kondo, S.2    Wang, B.3
  • 7
    • 0031581544 scopus 로고    scopus 로고
    • Expression of natural peptide antibiotics in human skin
    • Fulton C, Anderson GM, Zasloff M et al. (1997) Expression of natural peptide antibiotics in human skin. Lancet 350:1750-1
    • (1997) Lancet , vol.350 , pp. 1750-1751
    • Fulton, C.1    Anderson, G.M.2    Zasloff, M.3
  • 8
    • 0001475281 scopus 로고    scopus 로고
    • Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction
    • Garcia JR, Jaumann F, Schulz S et al. (2001) Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction. Cell Tissue Res 306:257-64
    • (2001) Cell Tissue Res , vol.306 , pp. 257-264
    • Garcia, J.R.1    Jaumann, F.2    Schulz, S.3
  • 9
    • 0030820726 scopus 로고    scopus 로고
    • A peptide antibiotic from human skin
    • Harder J, Bartels J, Christophers E et al. (1997) A peptide antibiotic from human skin. Nature 387:861
    • (1997) Nature , vol.387 , pp. 861
    • Harder, J.1    Bartels, J.2    Christophers, E.3
  • 10
    • 0035937107 scopus 로고    scopus 로고
    • Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic
    • Harder J, Bartels J, Christophers E et al. (2001) Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 276:5707-13
    • (2001) J Biol Chem , vol.276 , pp. 5707-5713
    • Harder, J.1    Bartels, J.2    Christophers, E.3
  • 11
    • 0034125829 scopus 로고    scopus 로고
    • Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia
    • Harder J, Meyer-Hoffert U, Teran LM et al. (2000) Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia. Am J Respir Cell Mol Biol 22:714-21
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 714-721
    • Harder, J.1    Meyer-Hoffert, U.2    Teran, L.M.3
  • 12
    • 4143097141 scopus 로고    scopus 로고
    • Differential gene induction of human beta-defensins (hBD-1, -2, -3, and -4) in keratinocytes is inhibited by retinoic acid
    • Harder J, Meyer-Hoffert U, Wehkamp K et al. (2004) Differential gene induction of human beta-defensins (hBD-1, -2, -3, and -4) in keratinocytes is inhibited by retinoic acid. J Invest Dermatol 123:522-9
    • (2004) J Invest Dermatol , vol.123 , pp. 522-529
    • Harder, J.1    Meyer-Hoffert, U.2    Wehkamp, K.3
  • 13
    • 0037195896 scopus 로고    scopus 로고
    • RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin
    • Harder J, Schroder JM (2002) RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin. J Biol Chem 277:46779-84
    • (2002) J Biol Chem , vol.277 , pp. 46779-46784
    • Harder, J.1    Schroder, J.M.2
  • 14
    • 16844370194 scopus 로고    scopus 로고
    • Psoriatic scales: A promising source for the isolation of human skin-derived antimicrobial proteins
    • Harder J, Schroder JM (2005) Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins. J Leukoc Biol 77:476-86
    • (2005) J Leukoc Biol , vol.77 , pp. 476-486
    • Harder, J.1    Schroder, J.M.2
  • 15
    • 34848918479 scopus 로고    scopus 로고
    • The constitutive capacity of human keratinocytes to kill Staphylococcus aureus is dependent on beta-defensin 3
    • Kisich KO, Howell MD, Boguniewicz M et al. (2007) The constitutive capacity of human keratinocytes to kill Staphylococcus aureus is dependent on beta-defensin 3. J Invest Dermatol 127:2368-80
    • (2007) J Invest Dermatol , vol.127 , pp. 2368-2380
    • Kisich, K.O.1    Howell, M.D.2    Boguniewicz, M.3
  • 16
    • 0036136328 scopus 로고    scopus 로고
    • Regulation of human beta-defensin-2 in gingival epithelial cells: The involvement of mitogen-activated protein kinase pathways, but not the NF-kappaB transcription factor family
    • Krisanaprakornkit S, Kimball JR, Dale BA (2002) Regulation of human beta-defensin-2 in gingival epithelial cells: the involvement of mitogen-activated protein kinase pathways, but not the NF-kappaB transcription factor family. J Immunol 168:316-24
    • (2002) J Immunol , vol.168 , pp. 316-324
    • Krisanaprakornkit, S.1    Kimball, J.R.2    Dale, B.A.3
  • 17
    • 0034020351 scopus 로고    scopus 로고
    • Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: Multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier
    • Krisanaprakornkit S, Kimball JR, Weinberg A et al. (2000) Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier. Infect Immun 68:2907-15
    • (2000) Infect Immun , vol.68 , pp. 2907-2915
    • Krisanaprakornkit, S.1    Kimball, J.R.2    Weinberg, A.3
  • 18
    • 36148999436 scopus 로고    scopus 로고
    • The antimicrobial peptide-sensing system aps of Staphylococcus aureus
    • Li M, Cha DJ, Lai Y et al. (2007a) The antimicrobial peptide-sensing system aps of Staphylococcus aureus. Mol Microbiol 66:1136-47
    • (2007) Mol Microbiol , vol.66 , pp. 1136-1147
    • Li, M.1    Cha, D.J.2    Lai, Y.3
  • 19
    • 34547201058 scopus 로고    scopus 로고
    • Gram-positive three-component antimicrobial peptide-sensing system
    • Li M, Lai Y, Villaruz AE et al. (2007b) Gram-positive three-component antimicrobial peptide-sensing system. Proc Natl Acad Sci USA 104: 9469-74
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9469-9474
    • Li, M.1    Lai, Y.2    Villaruz, A.E.3
  • 20
    • 0036178642 scopus 로고    scopus 로고
    • Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation
    • Liu AY, Destoumieux D, Wong AV et al. (2002) Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation. J Invest Dermatol 118:275-81
    • (2002) J Invest Dermatol , vol.118 , pp. 275-281
    • Liu, A.Y.1    Destoumieux, D.2    Wong, A.V.3
  • 21
    • 0033883797 scopus 로고    scopus 로고
    • Human melanoma progression in skin reconstructs: Biological significance of bFGF
    • Meier F, Nesbit M, Hsu MY et al. (2000) Human melanoma progression in skin reconstructs: biological significance of bFGF. Am J Pathol 156:193-200
    • (2000) Am J Pathol , vol.156 , pp. 193-200
    • Meier, F.1    Nesbit, M.2    Hsu, M.Y.3
  • 22
    • 10744222928 scopus 로고    scopus 로고
    • Toll-like receptor expression in human keratinocytes: Nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent
    • Mempel M, Voelcker V, Kollisch G et al. (2003) Toll-like receptor expression in human keratinocytes: nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent. J Invest Dermatol 121:1389-96
    • (2003) J Invest Dermatol , vol.121 , pp. 1389-1396
    • Mempel, M.1    Voelcker, V.2    Kollisch, G.3
  • 23
    • 23344434740 scopus 로고    scopus 로고
    • Staphylococcus aureus infection of epidermal keratinocytes promotes expression of innate antimicrobial peptides
    • Menzies BE, Kenoyer A (2005) Staphylococcus aureus infection of epidermal keratinocytes promotes expression of innate antimicrobial peptides. Infect Immun 73:5241-4
    • (2005) Infect Immun , vol.73 , pp. 5241-5244
    • Menzies, B.E.1    Kenoyer, A.2
  • 24
    • 33845476244 scopus 로고    scopus 로고
    • Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes
    • Menzies BE, Kenoyer A (2006) Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes. Infect Immun 74:6847-54
    • (2006) Infect Immun , vol.74 , pp. 6847-6854
    • Menzies, B.E.1    Kenoyer, A.2
  • 25
    • 0037973517 scopus 로고    scopus 로고
    • Staphylo-coccus aureus susceptibility to innate antimicrobial peptides, beta-defensins and CAP18, expressed by human keratinocytes
    • Midorikawa K, Ouhara K, Komatsuzawa H et al. (2003) Staphylo-coccus aureus susceptibility to innate antimicrobial peptides, beta-defensins and CAP18, expressed by human keratinocytes. Infect Immun 71:3730-9
    • (2003) Infect Immun , vol.71 , pp. 3730-3739
    • Midorikawa, K.1    Ouhara, K.2    Komatsuzawa, H.3
  • 26
    • 0034284803 scopus 로고    scopus 로고
    • Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination
    • Neish AS, Gewirtz AT, Zeng H et al. (2000) Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination. Science 289:1560-3
    • (2000) Science , vol.289 , pp. 1560-1563
    • Neish, A.S.1    Gewirtz, A.T.2    Zeng, H.3
  • 27
    • 0035839525 scopus 로고    scopus 로고
    • Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 mRNA production by Caco-2 cells
    • Ogushi K, Wada A, Niidome T et al. (2001) Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 mRNA production by Caco-2 cells. J Biol Chem 276:30521-6
    • (2001) J Biol Chem , vol.276 , pp. 30521-30526
    • Ogushi, K.1    Wada, A.2    Niidome, T.3
  • 28
    • 24944445440 scopus 로고    scopus 로고
    • Innate immunity in the skin: How keratinocytes fight against pathogens
    • Pivarcsi A, Nagy I, Kemeny L (2005) Innate immunity in the skin: how keratinocytes fight against pathogens. Curr Immunol Rev 1:29-42
    • (2005) Curr Immunol Rev , vol.1 , pp. 29-42
    • Pivarcsi, A.1    Nagy, I.2    Kemeny, L.3
  • 29
    • 52449127413 scopus 로고    scopus 로고
    • The role of antimicrobial peptides in human skin and in skin infectious diseases
    • Schittek B, Paulmann M, Senyurek I et al. (2008) The role of antimicrobial peptides in human skin and in skin infectious diseases. Infect Disord Drug Targets 8:135-43
    • (2008) Infect Disord Drug Targets , vol.8 , pp. 135-143
    • Schittek, B.1    Paulmann, M.2    Senyurek, I.3
  • 30
    • 33645051715 scopus 로고    scopus 로고
    • Antimicrobial skin peptides and proteins
    • Schroder JM, Harder J (2006) Antimicrobial skin peptides and proteins. Cell Mol Life Sci 63:469-86
    • (2006) Cell Mol Life Sci , vol.63 , pp. 469-486
    • Schroder, J.M.1    Harder, J.2
  • 31
    • 0038189571 scopus 로고    scopus 로고
    • Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors
    • Sorensen OE, Cowland JB, Theilgaard-Monch K et al. (2003) Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors. J Immunol 170:5583-9
    • (2003) J Immunol , vol.170 , pp. 5583-5589
    • Sorensen, O.E.1    Cowland, J.B.2    Theilgaard-Monch, K.3
  • 32
    • 17044367481 scopus 로고    scopus 로고
    • Differential regulation of beta-defensin expression in human skin by microbial stimuli
    • Sorensen OE, Thapa DR, Rosenthal A et al. (2005) Differential regulation of beta-defensin expression in human skin by microbial stimuli. J Immunol 174:4870-9
    • (2005) J Immunol , vol.174 , pp. 4870-4879
    • Sorensen, O.E.1    Thapa, D.R.2    Rosenthal, A.3
  • 33
    • 33745849146 scopus 로고    scopus 로고
    • Injury-induced innate immune response in human skin mediated by transactivation of the epidermal growth factor receptor
    • Sorensen OE, Thapa DR, Roupe KM et al. (2006) Injury-induced innate immune response in human skin mediated by transactivation of the epidermal growth factor receptor. J Clin Invest 116:1878-85
    • (2006) J Clin Invest , vol.116 , pp. 1878-1885
    • Sorensen, O.E.1    Thapa, D.R.2    Roupe, K.M.3
  • 34
    • 34548825389 scopus 로고    scopus 로고
    • Keratinocyte cytokine and chemokine receptors
    • vii
    • Tuzun Y, Antonov M, Dolar N et al. (2007) Keratinocyte cytokine and chemokine receptors. Dermatol Clin 25:467-76, vii
    • (2007) Dermatol Clin , vol.25 , pp. 467-476
    • Tuzun, Y.1    Antonov, M.2    Dolar, N.3
  • 35
    • 33644849605 scopus 로고    scopus 로고
    • NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2
    • Voss E, Wehkamp J, Wehkamp K et al. (2006) NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. J Biol Chem 281:2005-11
    • (2006) J Biol Chem , vol.281 , pp. 2005-2011
    • Voss, E.1    Wehkamp, J.2    Wehkamp, K.3
  • 36
    • 4644249955 scopus 로고    scopus 로고
    • NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: A novel effect of a probiotic bacterium
    • Wehkamp J, Harder J, Wehkamp K et al. (2004) NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium. Infect Immun 72:5750-8
    • (2004) Infect Immun , vol.72 , pp. 5750-5758
    • Wehkamp, J.1    Harder, J.2    Wehkamp, K.3
  • 37
    • 33644749261 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa- and IL-1beta-mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1
    • Wehkamp K, Schwichtenberg L, Schroder JM et al. (2006) Pseudomonas aeruginosa- and IL-1beta-mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1. J Invest Dermatol 126:121-7
    • (2006) J Invest Dermatol , vol.126 , pp. 121-127
    • Wehkamp, K.1    Schwichtenberg, L.2    Schroder, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.