Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection

Nature Immunology

Volumn 6, Issue 1, 2005, Pages 57-64

  Gläser, Regine ^a   Harder, Jürgen ^a   Lange, Hans ^b   Bartels, Joachim ^a   Christophers, Enno ^a   Schröder, Jens Michael ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN ANTIBODY; PROTEIN S 100; PSORIASIN; ZINC ION;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; ENTEROBACTER INFECTION; ESCHERICHIA COLI; EXPOSURE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INFECTION RESISTANCE; KERATINOCYTE; NONHUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION; SKIN INFECTION;

ANTI-BACTERIAL AGENTS; CALCIUM-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; SKIN; ZINC;

EID: 12344302254     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1142     Document Type: Article

References (40)

1. Klenha, J. & Krs, V. Lysozyme in mouse and human skin. J. Invest. Dermatol. 49, 396-399 (1967).
2. Wiedow, O., Harder, J., Bartels, J., Streit, V. & Christophers, E. Antileukoprotease in human skin: an antibiotic peptide constitutively produced by keratinocytes. Biochem. Biophys. Res. Common. 248, 904-909 (1998).
3. Harder, J. & Schroder, J.M. RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin. J. Biol. Chem. 277, 46779-46784 (2002).
4. Schittek, B. et al. Dermcidin: a novel human antibiotic peptide secreted by sweat glands. Nat. Immunol. 2, 1133-1137 (2001).
5. Harder, J., Bartels, J., Christophers, E. & Schroder, J.M. A peptide antibiotic from human skin. Nature 387, 861 (1997).
6. Harder, J., Bartels, J., Christophers, E. & Schroder, J.M. Isolation and characterization of human β-defensin-3, a novel human inducible peptide antibiotic. J. Biol. Chem. 276, 5707-5713 (2001).
7. Frohm, M. et al. The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders. J. Biol.Chem. 272, 15258-15263 (1997).
8. Nizet, V. et al. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 414, 454-457 (2001).
9. Ong, P.Y. et al. Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N. Engl. J. Med. 347, 1151-1160 (2002).
10. Casewell, M.W. & Desai, N. Survival of multiply-resistant Klebsiella aerogenes and other gram-negative bacilli on finger-tips. J. Hosp. Infect. 4, 350-360 (1983).
11. Noble, W.C. in The skin microflora and microbial disease (ed. Noble, W.C.) 210 (Cambridge University Press, Cambridge, UK, 1992).
12. Kulski, J.K., Lim, C.P., Dunn, D.S. & Bellgard, M. Genomic and phylogenetic analysis of the S100A7 (Psoriasin) gene duplications within the region of the S100 gene cluster on human chromosome 1q21. J. Mol. Evol. 56, 397-406 (2003).
13. Steinberg, D.A. & Lehrer, R.I. Designer assays for antimicrobia peptides. Disputing the "one-size-fits-all" theory. Methods Mol. Biol. 78, 169-186 (1997).
14. van der Merwe, D.E. et al. Biological variation in sweat sodium chloride conductivity. Ann. Clin. Biochem. 39, 39-43 (2002).
15. Zasloff, M. Antimicrobial peptides of multicellular organisms. Nature 415, 389-395 (2002).
16. Lagasse, E. & Clerc, R.G. Cloning and expression of two human genes encoding calcium-binding proteins that are regulated during myeloid differentiation. Mol. Cell. Biol. 8, 2402-2410 (1988).
17. Murthy, A.R., Lehrer, R.I., Harwig, S.S. & Miyasaki, K.T. In vitro candidastatic properties of the human neutrophil calprotectin complex. J. Immunol. 151, 6291-6301 (1993).
18. Clohessy, P.A. & Golden, B.E. Calprotectin-mediated zinc chelation as a biostatic mechanism in host defence. Scand. J. Immunol. 42, 551-556 (1995).
19. Sohnle, P.G., Hunter, M.J., Hahn, B. & Chazin, W.J. Zinc-reversible antimicrobial activity of recombinant calprotectin (migration inhibitory factor-related proteins 8 and 14). J. Infect. Dis. 182, 1272-1275 (2000).
20. 2+, inhibits lamin assembly, destabilizes nuclear architecture and may independently protect nuclei from apoptosis in vitro. Cell Calcium 23, 151-164 (1998).
21. Madsen, P. et al. Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin. J. Invest. Dermatol. 97 701-712 (1991).
22. Burgisser, D.M. et al. Amino acid sequence analysis of human S100A7 (psoriasin) by tandem mass spectrometry. Biochem. Biophys. Res. Commun. 217, 257-263 (1995).
23. Hagens, G. et al. Calcium-binding protein S100A7 and epidermal-type fatty acid-binding protein are associated in the cytosol of human keratinocytes. Biochem. J. 339, 419-427 (1999).
24. Celis, J.E. et al. Bladder squamous cell carcinomas express psoriasin and externalize it to the urine. J. Urol. 155 2105-2112 (1996).
25. Leygue, E. et al. Differential expression of psoriasin messenger RNA between in situ and invasive human breast carcinoma. Cancer Res. 56, 4606-4609 (1996).
26. Yoshio, H. et al. Antimicrobial polypeptides of human vernix caseosa and amniotic fluid: implications for newborn innate defense. Pediatr Res. 53, 211-216 (2003).
27. Heizmann, C.W., Fritz, G. & Schafer, B.W. S100 proteins: structure, functions and pathology. Front. Biosci. 7, d1356-1368 (2002).
28. Eckert, R.L. et al. S100 proteins in the epidermis. J. Invest. Dermatol. 123, 23-33 (2004).
29. Cole, A.M. et al. Calcitermin, a novel antimicrobial peptide isolated from human airway secretions. FEBS Lett. 504 5-10 (2001).
30. Travis, S.M. et al. Bactericidal activity of mammalian cathelicidin-derived peptides. Infect. Immun. 68, 2748-2755 (2000).
31. 2+-free states. Biochemistry 38, 1695-1704 (1999).
32. Ashoori, M. et al. Antibacterial activities of new synthetic divalent cation chelators. Microbiol. Immunol. 43, 311-316 (1999).
33. Gort, A.S., Ferber, D.M. & Imlay, J.A. The regulation and role of the periplasmic copper, zinc superoxide dismutase of Escherichia coli. Mol. Microbiol. 32, 179-191 (1999).
34. Benov, L., Sage, H. & Fridovich, I. The copper- and zinc-containing superoxide dismutase from Escherichia coli: molecular weight and stability. Arch. Biochem. Biophys. 340, 305-310 (1997).
35. Imlay, J.A. Pathways of oxidative damage. Annu. Rev. Microbiol. 57, 395-418 (2003).
36. Steinman, H.M. Function of periplasmic copper-zinc superoxide dismutase in Caulobacter crescentus. J. Bacteriol. 175, 1198-1202 (1993).
37. Sampson, B. et al. Hyperzincaemia and hypercalprotectinaemia: a new disorder of zinc metabolism. Lancet 360, 1742-1745 (2002).
38. Schroder, J.M. Identification and structural characterization of chemokines in lesional skin material of patients with inflammatory skin disease. Methods Enzymol. 288, 266-297 (1997).
39. Lange, H., Solterbeck, M., Berek, C. & Lemke, H. Correlation between immune maturation and idiotypic network recognition. Eur. J. Immunol. 26, 2234-2242 (1996).
40. Lange, H. et al. Reversal of the adult IgE high responder phenotype in mice by maternally transferred allergen-specific monoclonal IgG antibodies during a sensitive period in early ontogeny. Eur. J. Immunol. 32, 3133-3141 (2002).