Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

Nature Medicine

Volumn 13, Issue 8, 2007, Pages 975-980

  Yamasaki, Kenshi ^a   Di Nardo, Anna ^a   Bardan, Antonella ^a   Murakami, Masamoto ^b   Ohtake, Takaaki ^b   Coda, Alvin ^a   Dorschner, Robert A ^a   Bonnart, Chrystelle ^c,d   Descargues, Pascal ^c,d   Hovnanian, Alain ^c,d,e   Morhenn, Vera B ^a   Gallo, Richard L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

^c INSERM   (France)

^d UNIVERSITÉ DE TOULOUSE   (France)

^e TOULOUSE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATHELICIDIN; ENZYME; SERINE PROTEINASE; STRATUM CORNEUM TRYPTIC ENZYME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAMP GENE; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHEMA; GENE; GENE DELETION; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; ROSACEA; SKIN BIOPSY; SKIN INFLAMMATION; SPINK5 GENE; TELANGIECTASIA;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BIOPSY; CELLS, CULTURED; CYTOKINES; ENZYME ACTIVATION; HUMANS; INFLAMMATION; KERATINOCYTES; MICE; MICE, KNOCKOUT; ROSACEA; SERINE ENDOPEPTIDASES; SERPINS;

MUS;

EID: 34547660319     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1616     Document Type: Article

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