A hot-spot motif characterizes the interface between a designed ankyrin-repeat protein and its target ligand

Biophysical Journal

Volumn 102, Issue 3, 2012, Pages 407-416

  Cheung, Luthur Siu Lun ^a   Kanwar, Manu ^a   Ostermeier, Marc ^a   Konstantopoulos, Konstantinos ^a,b  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; LIGAND; MALTOSE BINDING PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; KINETICS; LIPID BILAYER; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR GENETICS; MUTATION; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN MOTIF; SPECTROSCOPY; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANKYRIN REPEAT; KINETICS; LIGANDS; LIPID BILAYERS; MALTOSE-BINDING PROTEINS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN ENGINEERING; SPECTRUM ANALYSIS; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

EID: 84856763445     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2012.01.004     Document Type: Article

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