메뉴 건너뛰기




Volumn 15, Issue 3, 2011, Pages 609-622

Potential non-hypoxic/ischemic causes of increased cerebral interstitial fluid lactate/pyruvate ratio: A review of available literature

Author keywords

Brain tissue oxygen; Cerebral metabolism; Cerebral microdialysis; Lactate pyruvate ratio; Microdialysis; Monitoring; Multimodality monitoring; Neurochemical monitoring; Subarachnoid hemorrhage; Traumatic brain injury

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADRENALIN; ALCOHOL; CATECHOLAMINE DERIVATIVE; DIAZEPAM; ESMOLOL; ETOMIDATE; GLUCOSE; GLUCOSE 6 PHOSPHATE; GLYCEROL; GLYCERYL TRINITRATE; HALOTHANE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ISOPRENALINE; LACTATE DEHYDROGENASE; LACTIC ACID; LORAZEPAM; METFORMIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITROPRUSSIDE SODIUM; PHENOBARBITAL; PHENYTOIN; PROPOFOL; PYRUVATE DEHYDROGENASE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; RITODRINE; VASOPRESSIN;

EID: 84856259120     PISSN: 15416933     EISSN: 15560961     Source Type: Journal    
DOI: 10.1007/s12028-011-9517-8     Document Type: Review
Times cited : (45)

References (140)
  • 1
    • 0016138960 scopus 로고
    • Functional correlates of dopamine neurotransmission
    • Ungerstedt U, Pycock C. Functional correlates of dopamine neurotransmission. Bull Schweiz Akad Med Wiss. 1974;30: 44-55.
    • (1974) Bull Schweiz Akad Med Wiss , vol.30 , pp. 44-55
    • Ungerstedt, U.1    Pycock, C.2
  • 3
    • 44649157689 scopus 로고    scopus 로고
    • Microdialysis and the neurochemistry of addiction
    • DOI 10.1016/j.pbb.2007.09.001, PII S009130570700278X
    • Torregrossa MM, Kalivas PW. Microdialysis and the neurochemistry of addiction. Pharmacol Biochem Behav. 2008;90: 261-72. (Pubitemid 351787343)
    • (2008) Pharmacology Biochemistry and Behavior , vol.90 , Issue.2 , pp. 261-272
    • Torregrossa, M.M.1    Kalivas, P.W.2
  • 4
    • 34250808936 scopus 로고    scopus 로고
    • Exercise and the brain: Insight in new therapeutic modalities
    • Meeusen R. Exercise and the brain: insight in new therapeutic modalities. Ann Transplant. 2005;10:49-51.
    • (2005) Ann Transplant , vol.10 , pp. 49-51
    • Meeusen, R.1
  • 5
    • 44649174358 scopus 로고    scopus 로고
    • Microdialysis of GABA and glutamate: Analysis, interpretation and comparison with microsensors
    • DOI 10.1016/j.pbb.2007.09.004, PII S0091305707002791
    • van der Zeyden M, Oldenziel WH, Rea K, Cremers TI, Westerink BH. Microdialysis of GABA and glutamate: analysis, interpretation and comparison with microsensors. Pharmacol Biochem Behav. 2008;90:135-47. (Pubitemid 351787344)
    • (2008) Pharmacology Biochemistry and Behavior , vol.90 , Issue.2 , pp. 135-147
    • Van Der Zeyden, M.1    Oldenziel, W.H.2    Rea, K.3    Cremers, T.I.4    Westerink, B.H.5
  • 6
    • 33645836476 scopus 로고    scopus 로고
    • Microdialysis as a tool in local pharmacodynamics
    • Li Y, Peris J, Zhong L, Derendorf H. Microdialysis as a tool in local pharmacodynamics. AAPS J. 2006;8:E222-35.
    • (2006) AAPS J , vol.8
    • Li, Y.1    Peris, J.2    Zhong, L.3    Derendorf, H.4
  • 8
    • 0025070115 scopus 로고
    • Extracellular measurements in the thalamus of parkinsonian patients
    • Meyerson BA, Linderoth B, Karlsson H, Ungerstedt U. Extracellular measurements in the thalamus of parkinsonian patients. Life Sci. 1990;46:301-8.
    • (1990) Life Sci , vol.46 , pp. 301-8
    • Meyerson, B.A.1    Linderoth, B.2    Karlsson, H.3    Ungerstedt, U.4
  • 9
    • 12544249525 scopus 로고    scopus 로고
    • Translational neurochemical research in acute human brain injury: The current status and potential future for cerebral microdialysis
    • Hillered L, Vespa PM, Hovda DA. Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis. J Neurotrauma. 2005; 22:3-41.
    • (2005) J Neurotrauma , vol.22 , pp. 3-41
    • Hillered, L.1    Vespa, P.M.2    Hovda, D.A.3
  • 11
    • 43549092825 scopus 로고    scopus 로고
    • Metabolic failure precedes intracranial pressure rises in traumatic brain injury: A microdialysis study
    • Belli A, Sen J, Petzold A, Russo S, Kitchen N, Smith M. Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study. Acta Neurochir (Wien). 2008;150:461-9.
    • (2008) Acta Neurochir (Wien) , vol.150 , pp. 461-9
    • Belli, A.1    Sen, J.2    Petzold, A.3    Russo, S.4    Kitchen, N.5    Smith, M.6
  • 12
    • 70349435311 scopus 로고    scopus 로고
    • Brain tissue lactate elevations predict episodes of intracranial hypertension in patients with traumatic brain injury
    • Adamides AA, Rosenfeldt FL, Winter CD, et al. Brain tissue lactate elevations predict episodes of intracranial hypertension in patients with traumatic brain injury. J Am Coll Surg. 2009; 209:531-9.
    • (2009) J Am Coll Surg , vol.209 , pp. 531-9
    • Adamides, A.A.1    Rosenfeldt, F.L.2    Winter, C.D.3
  • 13
    • 3042682565 scopus 로고    scopus 로고
    • Microdialysis in neurointensive care
    • DOI 10.2174/1381612043384105
    • Ungerstedt U, Rostami E. Microdialysis in neurointensive care. Curr Pharm Des. 2004;10:2145-52. (Pubitemid 38832756)
    • (2004) Current Pharmaceutical Design , vol.10 , Issue.18 , pp. 2145-2152
    • Ungerstedt, U.1    Rostami, E.2
  • 14
  • 15
    • 77952095796 scopus 로고    scopus 로고
    • Cerebral energy metabolism and microdialysis in neurocritical care
    • Nordström CH. Cerebral energy metabolism and microdialysis in neurocritical care. Childs Nerv Syst. 2010;26:465-72.
    • (2010) Childs Nerv Syst , vol.26 , pp. 465-72
    • Nordström, C.H.1
  • 16
    • 33745684731 scopus 로고    scopus 로고
    • Cerebral microdialysis: Research technique or clinical tool
    • Tisdall MM, Smith M. Cerebral microdialysis: research technique or clinical tool. Br J Anaesth. 2006;97:18-25.
    • (2006) Br J Anaesth , vol.97 , pp. 18-25
    • Tisdall, M.M.1    Smith, M.2
  • 17
    • 58149214725 scopus 로고    scopus 로고
    • Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury: A microdialysis study
    • Oddo M, Schmidt JM, Carrera E, et al. Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury: a microdialysis study. Crit Care Med. 2008;36: 3233-8.
    • (2008) Crit Care Med , vol.36 , pp. 3233-8
    • Oddo, M.1    Schmidt, J.M.2    Carrera, E.3
  • 19
    • 65249089614 scopus 로고    scopus 로고
    • Hemoglobin concentration and cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage
    • Oddo M, Milby A, Chen I, et al. Hemoglobin concentration and cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage. Stroke. 2009;40:1275-81.
    • (2009) Stroke , vol.40 , pp. 1275-81
    • Oddo, M.1    Milby, A.2    Chen, I.3
  • 20
    • 0037381748 scopus 로고    scopus 로고
    • Assessment of the lower limit for cerebral perfusion pressure in severe head injuries by bedside monitoring of regional energy metabolism
    • DOI 10.1097/00000542-200304000-00004
    • Nordström CH, Reinstrup P, Xu W, Gärdenfors A, Ungerstedt U. Assessment of the lower limit for cerebral perfusion pressure in severe head injuries by bedside monitoring of regional energy metabolism. Anesthesiology. 2003;98:809-14. (Pubitemid 36373212)
    • (2003) Anesthesiology , vol.98 , Issue.4 , pp. 809-814
    • Nordstrom, C.-H.1    Reinstrup, P.2    Xu, W.3    Gardenfors, A.4    Ungerstedt, U.5
  • 21
    • 36448969810 scopus 로고    scopus 로고
    • Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis
    • DOI 10.1097/01.CCM.0000295667.66853.BC
    • Vespa PM, Miller C, McArthur D, et al. Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis. Crit Care Med. 2007;35:2830-6. (Pubitemid 350175782)
    • (2007) Critical Care Medicine , vol.35 , Issue.12 , pp. 2830-2836
    • Vespa, P.M.1    Miller, C.2    McArthur, D.3    Eliseo, M.4    Etchepare, M.5    Hirt, D.6    Glenn, T.C.7    Martin, N.8    Hovda, D.9
  • 22
    • 58149170723 scopus 로고    scopus 로고
    • Persisting depletion of brain glucose following cortical spreading depression, despite apparent hyperaemia: Evidence for risk of an adverse effect of Leão's spreading depression
    • Hashemi P, Bhatia R, Nakamura H, et al. Persisting depletion of brain glucose following cortical spreading depression, despite apparent hyperaemia: evidence for risk of an adverse effect of Leão's spreading depression. J Cereb Blood Flow Metab. 2009; 29:166-75.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 166-75
    • Hashemi, P.1    Bhatia, R.2    Nakamura, H.3
  • 23
    • 0034893370 scopus 로고    scopus 로고
    • Predictive value of neurochemical monitoring in large middle cerebral artery infarction
    • Schneweis S, Grond M, Staub F, et al. Predictive value of neurochemical monitoring in large middle cerebral artery infarction. Stroke. 2001;32:1863-7.
    • (2001) Stroke , vol.32 , pp. 1863-7
    • Schneweis, S.1    Grond, M.2    Staub, F.3
  • 24
    • 37549043528 scopus 로고    scopus 로고
    • Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: Preliminary findings
    • Nortje J, Coles JP, Timofeev I, et al. Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings. Crit Care Med. 2008;36: 273-81.
    • (2008) Crit Care Med , vol.36 , pp. 273-81
    • Nortje, J.1    Coles, J.P.2    Timofeev, I.3
  • 25
    • 54549089085 scopus 로고    scopus 로고
    • Persistent metabolic crisis as measured by elevated cerebral microdialysis lactatepyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury
    • Marcoux J, McArthur DA, Miller C, et al. Persistent metabolic crisis as measured by elevated cerebral microdialysis lactatepyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury. Crit Care Med. 2008;36:2871-7.
    • (2008) Crit Care Med , vol.36 , pp. 2871-7
    • Marcoux, J.1    McArthur, D.A.2    Miller, C.3
  • 26
    • 33645282529 scopus 로고    scopus 로고
    • Continuous monitoring of cerebral metabolism in traumatic brain injury: A focus on cerebral microdialysis
    • Hillered L, Persson L, Nilsson P, Ronne-Engstrom E, Enblad P. Continuous monitoring of cerebral metabolism in traumatic brain injury: a focus on cerebral microdialysis. Curr Opin Crit Care. 2006;12:112-8.
    • (2006) Curr Opin Crit Care , vol.12 , pp. 112-8
    • Hillered, L.1    Persson, L.2    Nilsson, P.3    Ronne-Engstrom, E.4    Enblad, P.5
  • 27
    • 4944239339 scopus 로고    scopus 로고
    • Modeling cerebral arteriovenous lactate kinetics after intravenous lactate infusion in the rat
    • DOI 10.1097/01.WCB.0000129417.80261.A6
    • Leegsma-Vogt G, van der Werf S, Venema K, Korf J. Modeling cerebral arteriovenous lactate kinetics after intravenous lactate infusion in the rat. J Cereb Blood Flow Metab. 2004;24: 1071-80. (Pubitemid 39332146)
    • (2004) Journal of Cerebral Blood Flow and Metabolism , vol.24 , Issue.10 , pp. 1071-1080
    • Leegsma-Vogt, G.1    Van Der Werf, S.2    Venema, K.3    Korf, J.4
  • 28
    • 0022515756 scopus 로고
    • Regional kinetic constants for blood-brain barrier pyruvic acid transport in conscious rats by the monocarboxylic acid carrier
    • Miller LP, Oldendorf WH. Regional kinetic constants for bloodbrain barrier pyruvic acid transport in conscious rats by the monocarboxylic acid carrier. J Neurochem. 1986;46:1412-6. (Pubitemid 16062540)
    • (1986) Journal of Neurochemistry , vol.46 , Issue.5 , pp. 1412-1416
    • Miller, L.P.1    Oldendorf, W.H.2
  • 31
    • 0036549674 scopus 로고    scopus 로고
    • Advanced monitoring in the neurology intensive care unit: Microdialysis
    • Johnston AJ, Gupta AK. Advanced monitoring in the neurology intensive care unit: microdialysis. Curr Opin Crit Care. 2002;8: 121-7.
    • (2002) Curr Opin Crit Care , vol.8 , pp. 121-7
    • Johnston, A.J.1    Gupta, A.K.2
  • 32
    • 0034521193 scopus 로고    scopus 로고
    • Intracerebral microdialysis in clinical practice: Baseline values for chemical markers during wakefulness, anesthesia, and neurosurgery
    • Reinstrup P, Ståhl N, Mellergård P, Uski T, Ungerstedt U, Nordström CH. Intracerebral microdialysis in clinical practice: baseline values for chemical markers during wakefulness, anesthesia, and neurosurgery. Neurosurgery. 2000;47:701-9.
    • (2000) Neurosurgery , vol.47 , pp. 701-9
    • Reinstrup, P.1    Ståhl, N.2    Mellergård, P.3    Uski, T.4    Ungerstedt, U.5    Nordström, C.H.6
  • 33
    • 0036309090 scopus 로고    scopus 로고
    • Cerebral physiological and biochemical changes during vasogenic brain edema induced by intrathecal injection of bacterial lipopolysaccharides in piglets
    • Gårdenfors A, Nilsson F, Skagerberg G, Ungerstedt U, Nordstro ̈m CH. Cerebral physiological and biochemical changes during vasogenic brain edema induced by intrathecal injection of bacterial lipopolysaccharides in piglets. Acta Neurochir. 2002;144:601-8.
    • (2002) Acta Neurochir , vol.144 , pp. 601-8
    • Gårdenfors, A.1    Nilsson, F.2    Skagerberg, G.3    Ungerstedt, U.4    Nordström, C.H.5
  • 35
    • 18944405433 scopus 로고    scopus 로고
    • Metabolic crisis without brain ischemia is common after traumatic brain injury: A combined microdialysis and positron emission tomography study
    • Vespa P, Bergsneider M, Hattori N, et al. Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study. J Cereb Blood Flow Metab. 2005;25:763-4.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 763-4
    • Vespa, P.1    Bergsneider, M.2    Hattori, N.3
  • 36
    • 33747005066 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: Effects of pyruvate dehydrogenase complex deficiency and dichloroacetate
    • DOI 10.1016/j.ymgme.2006.04.015, PII S1096719206001727
    • Simpson NE, Han Z, Berendzen KM, et al. Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate. Mol Genet Metab. 2006;89:97-105. (Pubitemid 44205473)
    • (2006) Molecular Genetics and Metabolism , vol.89 , Issue.1-2 , pp. 97-105
    • Simpson, N.E.1    Han, Z.2    Berendzen, K.M.3    Sweeney, C.A.4    Oca-Cossio, J.A.5    Constantinidis, I.6    Stacpoole, P.W.7
  • 37
    • 0031080330 scopus 로고    scopus 로고
    • Clinical and biochemical aspects of thiamine treatment for metabolic acidosis during total parenteral nutrition
    • DOI 10.1016/S0899-9007(96)00384-X, PII S089990079600384X
    • Nakasaki H, Ohta M, Soeda J, et al. Clinical and biochemical aspects of thiamine treatment for metabolic acidosis during total parenteral nutrition. Nutrition. 1997;13:110-7. (Pubitemid 27172285)
    • (1997) Nutrition , vol.13 , Issue.2 , pp. 110-117
    • Nakasaki, H.1    Ohta, M.2    Soeda, J.3    Makuuchi, H.4    Tsuda, M.5    Tajima, T.6    Mitomi, T.7    Fujii, K.8
  • 40
    • 0026448257 scopus 로고
    • A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group
    • Stacpoole PW, Wright EC, Baumgartner TG, et al. A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group. NEJM. 1992;327:1564-9.
    • (1992) NEJM , vol.327 , pp. 1564-9
    • Stacpoole, P.W.1    Wright, E.C.2    Baumgartner, T.G.3
  • 41
    • 0023196089 scopus 로고
    • Deficiency of the reduced nicotinamide adenine dinucleotide dehydrogenase component of complex I of mitochondrial electron transport. Fatal infantile lactic acidosis and hypermetabolism with skeletal-cardiac myopathy and encephalopathy
    • Hoppel CL, Kerr DS, Dahms B, Roessmann U. Deficiency of the reduced nicotinamide adenine dinucleotide dehydrogenase component of complex I of mitochondrial electron transport. Fatal infantile lactic acidosis and hypermetabolism with skeletal- cardiac myopathy and encephalopathy. J Clin Invest. 1987; 80:71-7. (Pubitemid 17097518)
    • (1987) Journal of Clinical Investigation , vol.80 , Issue.1 , pp. 71-77
    • Hoppel, C.L.1    Kerr, D.S.2    Dahms, B.3    Roessmann, U.4
  • 42
    • 0021162081 scopus 로고
    • Deficiency of the iron-sulfur clusters of mitochondrial reduced nicotinamide-adenine dinucleotide-ubiquinone oxidoreductase (complex I) in an infant with congenital lactic acidosis
    • Moreadith RW, Batshaw ML, Ohnishi T, et al. Deficiency of the iron-sulfur clusters ofmitochondrial reduced nicotinamide-adenine dinucleotide-ubiquinone oxidoreductase (complex I) in an infant with congenital lactic acidosis. J Clin Invest. 1984;74:685-97. (Pubitemid 14031003)
    • (1984) Journal of Clinical Investigation , vol.74 , Issue.3 , pp. 685-697
    • Moreadith, R.W.1    Bathshaw, M.L.2    Ohnishi, T.3
  • 43
    • 0022368085 scopus 로고
    • Defective intramitochondrial NADH oxidation in skin fibroblasts from an infant with fatal neonatal lacticacidemia
    • Robinson BH, McKay N, Goodyer P, Lancaster G. Defective intramitochondrial NADH oxidation in skin fibroblasts from an infant with fatal neonatal lacitcacidemia. Am J Hum Genet. 1985;37:938-46. (Pubitemid 16224134)
    • (1985) American Journal of Human Genetics , vol.37 , Issue.5 , pp. 938-946
    • Robinson, B.H.1    McKay, N.2    Goodyer, P.3    Lancaster, G.4
  • 44
    • 77955151559 scopus 로고    scopus 로고
    • Succinyl-CoA ligase deficiency: A mitochondrial hepatoencephalomyopathy
    • Van Hove JL, Saenz MS, Thomas JA, et al. Succinyl-CoA ligase deficiency: a mitochondrial hepatoencephalomyopathy. Pediatr Res. 2010;68:159-64.
    • (2010) Pediatr Res , vol.68 , pp. 159-64
    • Van Hove, J.L.1    Saenz, M.S.2    Thomas, J.A.3
  • 45
    • 0018906694 scopus 로고
    • Abnormalities of carbohydrate metabolism in idiopathic Fanconi syndrome
    • Chesney RW, Kaplan BS, Colle E, et al. Abnormalities of carbohydrate metabolism in idiopathic Fanconi syndrome. Pediatr Res. 1980;14:209-15. (Pubitemid 10133514)
    • (1980) Pediatric Research , vol.14 , Issue.3 , pp. 209-215
    • Chesney, R.W.1    Kaplan, B.S.2    Colle, E.3
  • 46
    • 0020557211 scopus 로고
    • Mitochondrial cytochrome deficiency presenting as a myopathy with hypotonia, external ophthalmoplegia, and lactic acidosis in an infant and as fatal hepatopathy in a second cousin
    • Boustany RN, Aprille JR, Halperin J, Levy H, DeLong GR. Mitochondrial cytochrome deficiency presenting as a myopathy with hypotonia, external ophthalmoplegia, and lactic acidosis in an infant and as fatal hepatopathy in a second cousin. Ann Neurol. 1983;14:462-70. (Pubitemid 13010047)
    • (1983) Annals of Neurology , vol.14 , Issue.4 , pp. 462-470
    • Boustany, R.N.1    Aprille, J.R.2    Halperin, J.3
  • 47
    • 77049093212 scopus 로고    scopus 로고
    • Pyruvate therapy for Leigh syndrome due to cytochrome c oxidase deficiency
    • Komaki H, Nishigaki Y, Fuku N, et al. Pyruvate therapy for Leigh syndrome due to cytochrome c oxidase deficiency. Biochim Biophys Acta. 2010;1800:313-5.
    • (2010) Biochim Biophys Acta , vol.1800 , pp. 313-5
    • Komaki, H.1    Nishigaki, Y.2    Fuku, N.3
  • 49
    • 35448998940 scopus 로고    scopus 로고
    • Energy metabolism in brain cells: Effects of elevated ammonia concentrations
    • DOI 10.1007/s11011-007-9068-z
    • Hertz L, Kala G. Energy metabolism in brain cells: effects of elevated ammonia concentrations. Metab Brain Dis. 2007;22: 199-218. (Pubitemid 47624320)
    • (2007) Metabolic Brain Disease , vol.22 , Issue.3-4 , pp. 199-218
    • Hertz, L.1    Kala, G.2
  • 50
    • 0021967164 scopus 로고
    • Ammonia intoxication: Effects on cerebral cortex and spinal cord
    • DOI 10.1111/j.1471-4159.1985.tb08751.x
    • Lin S, Raabe W. Ammonia intoxication: effects on cerebral cortex and spinal cord. J Neurochem. 1985;44:1252-8. (Pubitemid 15107066)
    • (1985) Journal of Neurochemistry , vol.44 , Issue.4 , pp. 1252-1258
    • Lin, S.1    Raabe, W.2
  • 52
    • 0021279657 scopus 로고
    • Prevention of ammonia toxicity by L-carnitine: Metabolic changes in brain
    • O'Connor JE, Costell M, Grisolía S. Prevention of ammonia toxicity by L-carnitine: metabolic changes in brain. Neurochem Res. 1984;9:563-70. (Pubitemid 14120961)
    • (1984) Neurochemical Research , vol.9 , Issue.4 , pp. 563-570
    • O'Connor, J.E.1    Costell, M.2    Grisolia, S.3
  • 53
    • 0017362424 scopus 로고
    • Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts
    • Hindfelt B, Plum F, Duffy TE. Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts. J Clin Invest. 1977;59:386-96. (Pubitemid 8061207)
    • (1977) Journal of Clinical Investigation , vol.59 , Issue.3 , pp. 386-396
    • Hindfelt, B.1    Plum, F.2    Duffy, T.E.3
  • 54
    • 54449091991 scopus 로고    scopus 로고
    • Cerebral glutamine concentration and lactate-pyruvate ratio in patients with acute liver failure
    • Bjerring PN, Hauerberg J, Frederiksen HJ, et al. Cerebral glutamine concentration and lactate-pyruvate ratio in patients with acute liver failure. Neurocrit Care. 2008;9:3-7.
    • (2008) Neurocrit Care , vol.9 , pp. 3-7
    • Bjerring, P.N.1    Hauerberg, J.2    Frederiksen, H.J.3
  • 55
    • 0027377745 scopus 로고
    • Response of rat cerebral glycolytic enzymes to hyperammonemic states
    • DOI 10.1016/0304-3940(93)90134-7
    • Ratnakumari L, Murthy CR. Response of rat cerebral glycolytic enzymes to hyperammonemic states. Neurosci Lett. 1993;161: 37-40. (Pubitemid 23311059)
    • (1993) Neuroscience Letters , vol.161 , Issue.1 , pp. 37-40
    • Ratnakumari, L.1    Murthy, C.R.K.2
  • 56
    • 0031979199 scopus 로고    scopus 로고
    • Differential inhibition by hyperammonemia of the electron transport chain enzymes in synaptosomes and nonsynaptic mitochondria in ornithine transcarbamylase-deficient spf-Mice: Restoration by acetyl-L-carnitine
    • DOI 10.1023/A:1022406911604
    • Qureshi K, Rama Rao KV, Qureshi IA. Differential inhibition by hyperammonemia of the electron transport chain enzymes in synaptosomes and non-synaptic mitochondria in ornithine transcarbamylase-deficient spf-mice: restoration by acetyl-Lcarnitine. Neurochem Res. 1998;23:855-61. (Pubitemid 28178158)
    • (1998) Neurochemical Research , vol.23 , Issue.6 , pp. 855-861
    • Qureshi, K.1    Rao, K.V.R.2    Qureshi, I.A.3
  • 57
    • 0026752613 scopus 로고
    • Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice
    • Ratnakumari L, Qureshi IA, Butterworth RF. Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice. Biochem Biophys Res Commun. 1992;184:746-51.
    • (1992) Biochem Biophys Res Commun , vol.184 , pp. 746-51
    • Ratnakumari, L.1    Qureshi, I.A.2    Butterworth, R.F.3
  • 58
    • 77950555096 scopus 로고    scopus 로고
    • Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance
    • She P, Zhou Y, Zhang Z, Griffin K, Gowda K, Lynch CJ. Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance. J Appl Physiol. 2010;108:941-9.
    • (2010) J Appl Physiol , vol.108 , pp. 941-9
    • She, P.1    Zhou, Y.2    Zhang, Z.3    Griffin, K.4    Gowda, K.5    Lynch, C.J.6
  • 59
    • 0023653356 scopus 로고
    • Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates
    • Kauppinen RA, Sihra TS, Nicholls DG. Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates. Biochim Biophys Acta. 1987;930:173-8.
    • (1987) Biochim Biophys Acta , vol.930 , pp. 173-8
    • Kauppinen, R.A.1    Sihra, T.S.2    Nicholls, D.G.3
  • 60
    • 63449091161 scopus 로고    scopus 로고
    • Sustaining hypercitrullinemia, hypercholesterolemia and augmented oxidative stress in Japanese children with aspartate/glutamate carrier isoform 2-citrin-deficiency even during the silent period
    • Nagasaka H, Okano Y, Tsukahara H, et al. Sustaining hypercitrullinemia, hypercholesterolemia and augmented oxidative stress in Japanese children with aspartate/glutamate carrier isoform 2-citrin-deficiency even during the silent period. Mol Genet Metab. 2009;97:21-6.
    • (2009) Mol Genet Metab , vol.97 , pp. 21-6
    • Nagasaka, H.1    Okano, Y.2    Tsukahara, H.3
  • 61
    • 0036848476 scopus 로고    scopus 로고
    • Halothane, isoflurane and sevolfurane inhibit NADH: Ubiquinone oxidoreductase (complex I) of cardiac mitochondria
    • DOI 10.1113/jphysiol.2002.025015
    • Hanley PJ, Ray J, Brandt U, Daut J. Halothane, isoflurane and sevoflurane inhibit NADH:ubiquinone oxidoreductase (complex I) of cardiac mitochondria. J Physiol. 2002;544:687-93. (Pubitemid 35355950)
    • (2002) Journal of Physiology , vol.544 , Issue.3 , pp. 687-693
    • Hanley, P.J.1    Ray, J.2    Brandt, U.3    Daut, J.4
  • 62
    • 0016712892 scopus 로고
    • In vivo toxic effects of halothane on canine cerebral metabolic pathways
    • Michenfelder JD, Theye RA. In vivo toxic effects of halothane on canine cerebral metabolic pathways. Am J Physiol. 1975;229: 1050-5.
    • (1975) Am J Physiol , vol.229 , pp. 1050-5
    • Michenfelder, J.D.1    Theye, R.A.2
  • 63
    • 39049193418 scopus 로고    scopus 로고
    • Propofol is associated with impaired brain metabolism during hypothermic circulatory arrest: An experimental microdialysis study
    • Dahlbacka S, Mäkelä J, Kaakinen T, et al. Propofol is associated with impaired brain metabolism during hypothermic circulatory arrest: an experimental microdialysis study. Heart Surg Forum. 2006;9:E710-8.
    • (2006) Heart Surg Forum , vol.9
    • Dahlbacka, S.1    Mäkelä, J.2    Kaakinen, T.3
  • 65
    • 0031042580 scopus 로고    scopus 로고
    • Effect of the intravenous anesthetic 2,6-diisopropylphenol on respiration and energy production by rat brain synaptosomes
    • DOI 10.1023/A:1022438805337
    • Marian M, Parrino C, Leo AM, Vincenti E, Bindoli A, Scutari G. Effect of the intravenous anesthetic 2,6-diisopropylphenol on respiration and energy production by rat brain synaptosomes. Neurochem Res. 1997;22:287-92. (Pubitemid 27091817)
    • (1997) Neurochemical Research , vol.22 , Issue.3 , pp. 287-292
    • Marian, M.1    Parrino, C.2    Leo, A.M.3    Vincenti, E.4    Bindoli, A.5    Scutari, G.6
  • 66
    • 0025735434 scopus 로고
    • Influence of the anesthetic 2,6-diisopropylphenol on the oxidative phosphorylation of isolated rat liver mitochondria
    • Branca D, Roberti MS, Lorenzin P, Vincenti E, Scutari G. Influence of the anesthetic 2,6-diisopropylphenol on the oxidative phosphorylation of isolated rat liver mitochondria. Biochem Pharmacol. 1991;42:87-90.
    • (1991) Biochem Pharmacol , vol.42 , pp. 87-90
    • Branca, D.1    Roberti, M.S.2    Lorenzin, P.3    Vincenti, E.4    Scutari, G.5
  • 67
    • 67650116295 scopus 로고    scopus 로고
    • Propofol infusion syndrome: Update of clinical manifestation and pathophysiology
    • Fudickar A, Bein B. Propofol infusion syndrome: update of clinical manifestation and pathophysiology. Minerva Anestesiol. 2009;75:339-44.
    • (2009) Minerva Anestesiol , vol.75 , pp. 339-44
    • Fudickar, A.1    Bein, B.2
  • 68
    • 80052643951 scopus 로고    scopus 로고
    • Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage
    • doi:10.1007/s12028-010-9467-6
    • Pisapia JM, Wendell LC, Kumar MA, Zager EL, Levine JM. Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage. Neurocrit Care. 2010. doi:10.1007/s12028-010-9467-6.
    • (2010) Neurocrit Care
    • Pisapia, J.M.1    Wendell, L.C.2    Kumar, M.A.3    Zager, E.L.4    Levine, J.M.5
  • 69
    • 0027158745 scopus 로고
    • Effects of hypotensive anesthesia with sodium nitroprusside or isoflurane on hemodynamic and metabolic changes
    • Nam YT, Kim JS, Park KW. Effects of hypotensive anesthesia with sodium nitroprusside or isoflurane on hemodynamic and metabolic changes. Yonsei Med J. 1992;33:320-5.
    • (1992) Yonsei Med J , vol.33 , pp. 320-5
    • Nam, Y.T.1    Kim, J.S.2    Park, K.W.3
  • 70
    • 0017348737 scopus 로고
    • Cyanide release from sodium nitroprusside in the dog
    • Michenfelder JD. Cyanide release from sodium nitroprusside in the dog. Anesthesiology. 1977;46:196-201. (Pubitemid 8049365)
    • (1977) Anesthesiology , vol.46 , Issue.3 , pp. 196-201
    • Michenfelder, J.D.1
  • 71
    • 0018126660 scopus 로고
    • Cardiac cyanide toxicity by nitroprusside in the dog. Potential for reversal
    • Tinker JH, Michenfelder JD. Cardiac cyanide toxicity induced by nitroprusside in the dog: potential for reversal. Anesthesiology. 1978;49:109-16. (Pubitemid 9013598)
    • (1978) Anesthesiology , vol.49 , Issue.2 , pp. 109-116
    • Tinker, J.H.1    Michenfelder, J.D.2
  • 72
    • 77956394303 scopus 로고    scopus 로고
    • Mitochondrial dysfunction induced by statin contributes to endothelial dysfunction in patients with coronary artery disease
    • Dai YL, Luk TH, Siu CW, et al. Mitochondrial dysfunction induced by statin contributes to endothelial dysfunction in patients with coronary artery disease. Cardiovasc Toxicol. 2010;10:130-8.
    • (2010) Cardiovasc Toxicol , vol.10 , pp. 130-8
    • Dai, Y.L.1    Luk, T.H.2    Siu, C.W.3
  • 73
    • 0015265455 scopus 로고
    • Toxicology, metabolism, and biochemistry of 1,2- propanediol
    • Ruddick JA. Toxicology, metabolism, and biochemistry of 1,2- propanediol. Toxicol Appl Pharmacol. 1972;21:102-11.
    • (1972) Toxicol Appl Pharmacol , vol.21 , pp. 102-11
    • Ruddick, J.A.1
  • 74
    • 0027466201 scopus 로고
    • Effect of propane-1,2-diol ingestion on carbohydrate metabolism in female rat erythrocytes
    • DOI 10.1002/jat.2550130114
    • Saini M, Nagpaul JP, Amma MK. Effect of propane-1,2-diol ingestion on carbohydrate metabolism in female rat erythrocytes. J Appl Toxicol. 1993;13:69-75. (Pubitemid 23032665)
    • (1993) Journal of Applied Toxicology , vol.13 , Issue.1 , pp. 69-75
    • Saini, M.1    Nagpaul, J.P.2    Amma, M.K.P.3
  • 76
    • 0024601229 scopus 로고
    • Effects of propylene glycol on redox state of the perfuse rat liver - A note of caution
    • DOI 10.1007/BF01856027
    • Schölmerich J, Kitamura S, Miyai K. Effects of propylene glycol on redox state of the perfused rat liver - a note of caution. Res Exp Med (Berl). 1989;189:39-42. (Pubitemid 19064018)
    • (1989) Research in Experimental Medicine , vol.189 , Issue.1 , pp. 39-42
    • Scholmerich, J.1    Kitamura, S.2    Miyai, K.3
  • 77
    • 24944459735 scopus 로고    scopus 로고
    • Propylene glycol toxicity: A severe iatrogenic illness in ICU patients receiving IV benzodiazepines
    • Wilson KC, Reardon C, Theodore AC, Farber HW. Propylene glycol toxicity: a severe iatrogenic illness in ICU patients receiving IV benzodiazepines. Chest. 2005;128:1674-81.
    • (2005) Chest , vol.128 , pp. 1674-81
    • Wilson, K.C.1    Reardon, C.2    Theodore, A.C.3    Farber, H.W.4
  • 78
    • 30544455514 scopus 로고    scopus 로고
    • Osmol gap as a surrogate marker for serum propylene glycol concentrations in patients receiving lorazepam for sedation
    • DOI 10.1592/phco.2006.26.1.23
    • Barnes BJ, Gerst C, Smith JR, Terrell AR, Mullins ME. Osmol gap as a surrogate marker for serum propylene glycol concentrations in patients receiving lorazepam for sedation. Pharmacotherapy. 2006;26:23-33. (Pubitemid 43082924)
    • (2006) Pharmacotherapy , vol.26 , Issue.1 , pp. 23-33
    • Barnes, B.J.1    Gerst, C.2    Smith, J.R.3    Terrell, A.R.4    Mullins, M.E.5
  • 79
    • 46249096897 scopus 로고    scopus 로고
    • Hyperosmolar, increased-anion-gap metabolic acidosis and hyperglycemia after etomidate infusion
    • DOI 10.1016/j.jclinane.2007.12.010, PII S0952818007003728
    • Ganesh A, Audu P. Hyperosmolar, increased-anion-gap metabolic acidosis and hyperglycemia after etomidate infusion. J Clin Anesth. 2008;20:290-3. (Pubitemid 351915826)
    • (2008) Journal of Clinical Anesthesia , vol.20 , Issue.4 , pp. 290-293
    • Ganesh, A.1    Audu, P.2
  • 81
    • 34249977584 scopus 로고    scopus 로고
    • Recognition, treatment, and prevention of propylene glycol toxicity
    • Zar T, Graeber C, Perazella MA. Recognition, treatment, and prevention of propylene glycol toxicity. Sem Dial. 2007;20: 217-9.
    • (2007) Sem Dial , vol.20 , pp. 217-9
    • Zar, T.1    Graeber, C.2    Perazella, M.A.3
  • 84
    • 0021237738 scopus 로고
    • The effects of metformin compared to the effects of phenformin on the lactate production and the metabolism of isolated parenchymal rat liver cell
    • Jalling O, Olsen C. The effects of metformin compared to the effects of phenformin on the lactate production and the metabolism of isolated parenchymal rat liver cell. Acta Pharmacol Toxicol (Copenh). 1984;54:327-32. (Pubitemid 14100955)
    • (1984) Acta Pharmacologica et Toxicologica , vol.54 , Issue.5 , pp. 327-332
    • Jalling, O.1    Olsen, C.2
  • 85
    • 0018758962 scopus 로고
    • Metabolic effects of combined sulphonylurea and metformin therapy in maturity-onset diabetes
    • Nattrass M, Hinks L, Smythe P, Todd PG, Alberti KGMM. Metabolic effects of combined sulphonylurea and metformin therapy in maturity-onset diabetes. Horm Metab Res. 1979;11: 332-7. (Pubitemid 9212064)
    • (1979) Hormone and Metabolic Research , vol.11 , Issue.5 , pp. 332-337
    • Nattrass, M.1    Hinks, L.2    Smythe, P.3
  • 86
    • 0021360702 scopus 로고
    • Concentrations of lactate and pyruvate in maternal and neonatal blood with different intravenous fluids used for prehydration before epidural anesthesia
    • Ramanathan S, Masih AK, Ashok U, Arismendy J, Turndorf H. Concentrations of lactate and pyruvate in maternal and neonatal blood with different intravenous fluids used for prehydration before epidural anesthesia. Anesth Analg. 1984;63:69-74. (Pubitemid 14216415)
    • (1984) Anesthesia and Analgesia , vol.63 , Issue.1 , pp. 69-74
    • Ramanathan, S.1    Masih, A.K.2    Ashok, U.3
  • 88
    • 34547761212 scopus 로고    scopus 로고
    • Astrocyte glycogen and brain energy metabolism
    • DOI 10.1002/glia.20557
    • Brown AM, Ransom BR. Astrocyte glycogen and brain energy metabolism. Glia. 2007;55:1263-71. (Pubitemid 47235367)
    • (2007) GLIA , vol.55 , Issue.12 , pp. 1263-1271
    • Brown, A.M.1    Ransom, B.R.2
  • 91
    • 0018178123 scopus 로고
    • Cerebral metabolic changes in profound, insulin-induced hypoglycemia, and in the recovery period following glucose administration
    • Agardh CD, Folbergrová J, Siesjö BK. Cerebral metabolic changes in profound, insulin-induced hypoglycemia, and in the recovery period following glucose administration. J Neurochem. 1978;31:1135-42. (Pubitemid 9039031)
    • (1978) Journal of Neurochemistry , vol.31 , Issue.5 , pp. 1135-1142
    • Agardh, C.-D.1    Folbergrova, J.2    Siesjo, B.K.3
  • 92
    • 0026025708 scopus 로고
    • Changes in pyruvate dehydrogenase complex activity during and following severe insulininduced hypoglycemia
    • Cardell M, Siesjö BK, Wieloch T. Changes in pyruvate dehydrogenase complex activity during and following severe insulininduced hypoglycemia. J Cereb Blood Flow Metab. 1991;11: 122-8.
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 122-8
    • Cardell, M.1    Siesjö, B.K.2    Wieloch, T.3
  • 93
    • 40549083624 scopus 로고    scopus 로고
    • Hyperglycemia and cerebral glucose in aneurysmal subarachnoid hemorrhage
    • DOI 10.1007/s00134-008-1044-5
    • Schlenk F, Nagel A, Graetz D, Sarrafzadeh AS. Hyperglycemia and cerebral glucose in aneurysmal subarachnoid hemorrhage. Intensive Care Med. 2008;34:1200-7. (Pubitemid 351904294)
    • (2008) Intensive Care Medicine , vol.34 , Issue.7 , pp. 1200-1207
    • Schlenk, F.1    Nagel, A.2    Graetz, D.3    Sarrafzadeh, A.S.4
  • 94
    • 33644585056 scopus 로고    scopus 로고
    • Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury
    • Vespa P, Boonyaputthikul R, McArthur DL, et al. Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury. Crit Care Med. 2006;34:850-6.
    • (2006) Crit Care Med , vol.34 , pp. 850-6
    • Vespa, P.1    Boonyaputthikul, R.2    McArthur, D.L.3
  • 96
    • 0034981078 scopus 로고    scopus 로고
    • In vivo measurements of brain glucose transport using the reversible michaelis-menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia
    • Choi IY, Lee SP, Kim SG, Gruetter R. In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia. J Cereb Blood Flow Metab. 2001;21:653-63. (Pubitemid 32510453)
    • (2001) Journal of Cerebral Blood Flow and Metabolism , vol.21 , Issue.6 , pp. 653-663
    • Choi, I.-Y.1    Lee, S.-P.2    Kim, S.-G.3    Gruetter, R.4
  • 97
    • 0031830592 scopus 로고    scopus 로고
    • Sustained elevation of cerebral blood flow after hypoglycaemia in normal man
    • DOI 10.1016/S0168-8227(98)00031-X, PII S016882279800031X
    • Eckert B, Ryding E, Agardh CD. Sustained elevation of cerebral blood flow after hypoglycaemia in normal man. Diabetes Res Clin Pract. 1998;40:91-100. (Pubitemid 28308399)
    • (1998) Diabetes Research and Clinical Practice , vol.40 , Issue.2 , pp. 91-100
    • Eckert, B.1    Ryding, E.2    Agardh, C.-D.3
  • 98
    • 0031903645 scopus 로고    scopus 로고
    • Influence of adrenergic agonists on the release of amino acids from rat skeletal muscle studied by microdialysis
    • DOI 10.1046/j.1365-201X.1998.00341.x
    • Rosdahl H, Samuelsson AC, Ungerstedt U, Henriksson J. Influence of adrenergic agonists on the release of amino acids from rat skeletal muscle studied by microdialysis. Acta Physiol Scand. 1998;163:349-60. (Pubitemid 28375767)
    • (1998) Acta Physiologica Scandinavica , vol.163 , Issue.4 , pp. 349-360
    • Rosdahl, H.1    Samuelsson, A.-C.2    Ungerstedt, U.3    Henriksson, J.4
  • 99
    • 0347296030 scopus 로고    scopus 로고
    • Effects of epinephrine and norepinephrine on hemodynamics, oxidative metabolism, and organ energetics in endotoxemic rats
    • Levy B, Mansart A, Bollaert PE, Franck P, Mallie JP. Effects of epinephrine and norepinephrine on hemodynamics, oxidative metabolism, and organ energetics in endotoxemic rats. Intensive Care Med. 2003;29:292-300. (Pubitemid 36384420)
    • (2003) Intensive Care Medicine , vol.29 , Issue.2 , pp. 292-300
    • Levy, B.1    Mansart, A.2    Bollaert, P.-E.3    Franck, P.4    Mallie, J.-P.5
  • 100
    • 0030965638 scopus 로고    scopus 로고
    • Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: A prospective, randomized study
    • DOI 10.1007/s001340050329
    • Levy B, Bollaert PE, Charpentier C, et al. Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: a prospective, randomized study. Intensive Care Med. 1997;23:282-7. (Pubitemid 27129993)
    • (1997) Intensive Care Medicine , vol.23 , Issue.3 , pp. 282-287
    • Levy, B.1    Bollaert, P.-E.2    Charpentier, C.3    Nace, L.4    Audibert, G.5    Bauer, Ph.6    Nabet, P.7    Larcan, A.8
  • 101
    • 0021186340 scopus 로고
    • Metabolic effects of adrenaline and noradrenaline in man: Studies with somatostatin
    • Pernet A, Walker M, Gill GV, Ørskov H, Alberti KGMM, Johnston DG. Metabolic effects of adrenaline and noradrenaline in man: studies with somatostatin. Diabete Metab. 1984;10: 98-105. (Pubitemid 14079761)
    • (1984) Diabete et Metabolisme , vol.10 , Issue.2 , pp. 98-105
    • Pernet, A.1    Walker, M.2    Gill, G.V.3
  • 102
    • 0016801947 scopus 로고
    • Plasma catecholamines and blood substrate concentrations: Studies in insulin induced hypoglycaemia and after adrenaline infusions
    • Christensen NJ, Alberti KG, Brandsborg O. Plasma catecholamines and blood substrate concentrations: studies in insulin induced hypoglycaemia and after adrenaline infusions. Eur J Clin Invest. 1975;5:415-23.
    • (1975) Eur J Clin Invest , vol.5 , pp. 415-23
    • Christensen, N.J.1    Alberti, K.G.2    Brandsborg, O.3
  • 103
    • 39549095616 scopus 로고    scopus 로고
    • The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass grafting
    • Heringlake M, Wernerus M, Grünefeld J, et al. The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass grafting. Crit Care. 2007;11:R51.
    • (2007) Crit Care , vol.11
    • Heringlake, M.1    Wernerus, M.2    Grünefeld, J.3
  • 104
    • 0021864508 scopus 로고
    • Effects of intravenous ritodrine on lactate and pyruvate levels: Role of glycemia and anaerobiosis
    • Cano A, Martínez P, Parrilla JJ, Abad L. Effects of intravenous ritodrine on lactate and pyruvate levels: role of glycemia and anaerobiosis. Obstet Gynecol. 1985;66:207-10. (Pubitemid 15049723)
    • (1985) Obstetrics and Gynecology , vol.66 , Issue.2 , pp. 207-210
    • Cano, A.1    Martinez, P.2    Parrilla, J.J.3    Abad, L.4
  • 105
  • 106
    • 0022443686 scopus 로고
    • Effect of sepsis on activity of pyruvate dehydrogenase complex in skeletal muscle and liver
    • Vary TC, Siegel JH, Nakatani T, Sato T, Aoyama H. Effect of sepsis on activity of pyruvate dehydrogenase complex in skeletal muscle and liver. Am J Physiol. 1986;250:E634-40.
    • (1986) Am J Physiol , vol.250
    • Vary, T.C.1    Siegel, J.H.2    Nakatani, T.3    Sato, T.4    Aoyama, H.5
  • 107
    • 0030990451 scopus 로고    scopus 로고
    • Protective effects of succinic acid dimethyl ester infusion in experimental endotoxemia
    • Malaisse WJ, Nadi AB, Ladriere L, Zhang TM. Protective effects of succinic acid dimethyl ester infusion in experimental endotoxemia. Nutrition. 1997;13:330-41.
    • (1997) Nutrition , vol.13 , pp. 330-41
    • Malaisse, W.J.1    Nadi, A.B.2    Ladriere, L.3    Zhang, T.M.4
  • 108
    • 67649383319 scopus 로고    scopus 로고
    • Moderate hypercapnia exerts beneficial effects on splanchnic energy metabolism during endotoxemia
    • Gnaegi A, Feihl F, Boulat O, Waeber B, Liaudet L. Moderate hypercapnia exerts beneficial effects on splanchnic energy metabolism during endotoxemia. Intensive Care Med. 2009;35: 1297-304.
    • (2009) Intensive Care Med , vol.35 , pp. 1297-304
    • Gnaegi, A.1    Feihl, F.2    Boulat, O.3    Waeber, B.4    Liaudet, L.5
  • 109
    • 60849086756 scopus 로고    scopus 로고
    • Renal haemodynamic, microcirculatory, metabolic and histopathological responses to peritonitis-induced septic shock in pigs
    • Chvojka J, Sykora R, Krouzecky A, et al. Renal haemodynamic, microcirculatory, metabolic and histopathological responses to peritonitis-induced septic shock in pigs. Crit Care. 2008;12: R164.
    • (2008) Crit Care , vol.12
    • Chvojka, J.1    Sykora, R.2    Krouzecky, A.3
  • 110
  • 111
    • 0023815459 scopus 로고
    • Early impairment of oxidative metabolism and energy production in severe sepsis
    • Astiz M, Rackow EC, Weil MH, Schumer W. Early impairment of oxidative metabolism and energy production in severe sepsis. Circ Shock. 1988;26:311-20. (Pubitemid 18268355)
    • (1988) Circulatory Shock , vol.26 , Issue.3 , pp. 311-320
    • Astiz, M.1    Rackow, E.C.2    Weil, M.H.3    Schumer, W.4
  • 112
    • 0018669481 scopus 로고
    • Cerebral metabolic and circulatory changes in the rat during sustained seizures induced by DL-homocysteine
    • DOI 10.1016/0006-8993(79)90497-9
    • Blennow G, Folbergrová J, Nilsson B, Siesjö BK. Cerebral metabolic and circulatory changes in the rat during sustained seizures induced by DL-homocysteine. Brain Res. 1979;179: 129-46. (Pubitemid 10217476)
    • (1979) Brain Research , vol.179 , Issue.1 , pp. 129-146
    • Blennow, G.1    Folbergrova, J.2    Nilsson, B.3    Siesjo, B.K.4
  • 113
    • 33947625069 scopus 로고    scopus 로고
    • Mitochondrial complex I inhibition in cerebral cortex of immature rats following homocysteic acid-induced seizures
    • DOI 10.1016/j.expneurol.2006.12.010, PII S0014488606006431
    • Folbergrová J, Jesina P, Drahota Z, et al. Mitochondrial complex I inhibition in cerebral cortex of immature rats following homocysteic acid-induced seizures. Exp Neurol. 2007;204:597-609. (Pubitemid 46497046)
    • (2007) Experimental Neurology , vol.204 , Issue.2 , pp. 597-609
    • Folbergrova, J.1    Jesina, P.2    Drahota, Z.3    Lisy, V.4    Haugvicova, R.5    Vojtiskova, A.6    Houstek, J.7
  • 114
    • 0018376417 scopus 로고
    • Metabolic responses to status epilepticus in the rat, cat, and mouse
    • Howse DCN. Metabolic responses to status epilepticus in the rat, cat, and mouse. Can J Physiol Pharmacol. 1979;57:205-12. (Pubitemid 9116979)
    • (1979) Canadian Journal of Physiology and Pharmacology , vol.57 , Issue.2 , pp. 205-212
    • Howse, D.C.N.1
  • 115
    • 0021804558 scopus 로고
    • Cerebral metabolic changes during and following fluorothyl-induced seizures in ventilated rats
    • DOI 10.1111/j.1471-4159.1985.tb08778.x
    • Folbergrová J, Ingvar M, Nevander G, Siesjö BK. Cerebral metabolic changes during and following fluorothyl-induced seizures in ventilated rats. J Neurochem. 1985;44:1419-26. (Pubitemid 15056909)
    • (1985) Journal of Neurochemistry , vol.44 , Issue.5 , pp. 1419-1426
    • Folbergrova, J.1    Ingvar, M.2    Nevander, G.3    Siesjo, B.K.4
  • 116
    • 0023100875 scopus 로고
    • Metabolic alterations underlying the development of hypermetabolic necrosis in the substantia nigra in status epilepticus
    • Ingvar M, Folbergrová J, Siesjö BK. Metabolic alterations underlying the development of hypermetabolic necrosis in the substantia nigra in status epilepticus. J Cereb Blood Flow Metab. 1987;7:103-8. (Pubitemid 17018322)
    • (1987) Journal of Cerebral Blood Flow and Metabolism , vol.7 , Issue.1 , pp. 103-108
    • Ingvar, M.1    Folbegrova, J.2    Siesjo, B.K.3
  • 117
    • 0017686105 scopus 로고
    • Cerebral metabolic changes during prolonged epileptic seizures in rats
    • Chapman AG, Meldrum BS, Siesjö BK. Cerebral metabolic changes during prolonged epileptic seizures in rats. J Neurochem. 1977;28:1025-35. (Pubitemid 8098870)
    • (1977) Journal of Neurochemistry , vol.28 , Issue.5 , pp. 1025-1035
    • Chapman, A.G.1    Meldrum, B.S.2    Siesjo, B.K.3
  • 118
    • 0021827127 scopus 로고
    • Cerebral energy metabolism during bicuculline-induced status epilepticus in spontaneously hypertensive rats
    • Johansson BB, Fredriksson K. Cerebral energy metabolism during bicuculline-induced status epilepticus in spontaneously hypertensive rats. Acta Phys Scand. 1985;123:299-302. (Pubitemid 15033593)
    • (1985) Acta Physiologica Scandinavica , vol.123 , Issue.3 , pp. 299-302
    • Johansson, B.B.1    Fredriksson, K.2
  • 119
    • 37549052954 scopus 로고    scopus 로고
    • Brain metabolism and diffusion in the rat cerebral cortex during pilocarpine-induced status epilepticus
    • Slais K, Vorisek I, Zoremba N, Homola A, Dmytrenko L, Sykova E. Brain metabolism and diffusion in the rat cerebral cortex during pilocarpine-induced status epilepticus. Exp Neurol. 2008;209:145-54.
    • (2008) Exp Neurol , vol.209 , pp. 145-54
    • Slais, K.1    Vorisek, I.2    Zoremba, N.3    Homola, A.4    Dmytrenko, L.5    Sykova, E.6
  • 120
    • 21544460980 scopus 로고    scopus 로고
    • Metabolic changes in rat striatum following convulsive seizures
    • DOI 10.1016/j.brainres.2005.05.030, PII S0006899305007730
    • Darbin O, Risso JJ, Carre E, Lonjon M, Naritoku DK. Metabolic changes in rat striatum following convulsive seizures. Brain Res. 2005;1050:124-9. (Pubitemid 40922725)
    • (2005) Brain Research , vol.1050 , Issue.1-2 , pp. 124-129
    • Darbin, O.1    Risso, J.J.2    Carre, E.3    Lonjon, M.4    Naritoku, D.K.5
  • 121
    • 34748925344 scopus 로고    scopus 로고
    • Electrographic seizures and periodic discharges after intracerebral hemorrhage
    • Claassen J, Jetté N, Chum F, et al. Electrographic seizures and periodic discharges after intracerebral hemorrhage. Neurology. 2007;69:1256-65.
    • (2007) Neurology , vol.69 , pp. 1256-65
    • Claassen, J.1    Jetté, N.2    Chum, F.3
  • 122
    • 0015426930 scopus 로고
    • The effect of moderate and marked hypercapnia upon the energy state and upon the cytoplasmic NADH-NAD+ ratio of the rat brain
    • Folbergrová J, MacMillan V, Siesjö BK. The effect of moderate and marked hypercapnia upon the energy state and upon the cytoplasmic NADH-NAD+ ratio of the rat brain. J Neurochem. 1972;19:2497-505.
    • (1972) J Neurochem , vol.19 , pp. 2497-505
    • Folbergrová, J.1    MacMillan, V.2    Siesjö, B.K.3
  • 123
    • 0016258481 scopus 로고
    • Patterns of changes in brain carbohydrate metabolites, amino acids and organic phosphates at increased carbon dioxide tensions
    • Folbergrová J, Pontén U, Siesjö BK. Patterns of changes in brain carbohydrate metabolites, amino acids and organic phosphates at increased carbon dioxide tensions. J Neurochem. 1974;22: 1115-25.
    • (1974) J Neurochem , vol.22 , pp. 1115-25
    • Folbergrová, J.1    Pontén, U.2    Siesjö, B.K.3
  • 124
    • 0014708917 scopus 로고
    • Effects of carbon dioxide, bicarbonate, and pH on lactate and pyruvate in the brain of rats
    • Weyne J, Demeester G, Leusen I. Effects of carbon dioxide, bicarbonate, and pH on lactate and pyruvate in the brain of rats. Pflugers Arch. 1970;31:292-311.
    • (1970) Pflugers Arch , vol.31 , pp. 292-311
    • Weyne, J.1    Demeester, G.2    Leusen, I.3
  • 125
    • 0014558933 scopus 로고
    • The regulation of extra- and intracellular acid-base parameters in the rat brain during hyperand hypocapnia
    • Kjällquist A ̊ , Nardini M, Siesjö BK. The regulation of extra- and intracellular acid-base parameters in the rat brain during hyperand hypocapnia. Acta Physiol Scand. 1969;76:485-94.
    • (1969) Acta Physiol Scand , vol.76 , pp. 485-94
    • Kjällquist, Å.1    Nardini, M.2    Siesjö, B.K.3
  • 126
    • 0014489175 scopus 로고
    • The effects of hypercapnia and hypocapnia upon the cerebrospinal fluid lactate and pyruvate concentrations and upon the lactate, pyruvate, ATP, ADP, phosphocreatine and creatine concentrations of cat brain tissue
    • Granholm L, Siesjö BK. The effects of hypercapnia and hypocapnia upon the cerebrospinal fluid lactate and pyruvate concentrations and upon the lactate, pyruvate, ATP, ADP, phosphocreatine and creatine concentrations of cat brain tissue. Acta Physiol Scand. 1969;75:257-66.
    • (1969) Acta Physiol Scand , vol.75 , pp. 257-66
    • Granholm, L.1    Siesjö, B.K.2
  • 128
    • 0016780678 scopus 로고
    • Zum verhalten von laktat und pyruvat sowie des laktat/pyruvat-quotienten im blut bei schilddru ̈senfunktionsstörungen des menschen
    • Hübner G, Schwinger E, Meng W. Zum verhalten von laktat und pyruvat sowie des laktat/pyruvat-quotienten im blut bei schilddru ̈ senfunktionsstörungen des menschen. Z Gesamte Inn Med. 1975;30:786-9.
    • (1975) Z Gesamte Inn Med , vol.30 , pp. 786-9
    • Hübner, G.1    Schwinger, E.2    Meng, W.3
  • 129
  • 132
    • 0018878788 scopus 로고
    • Alcohol intoxication and hangover: Modification of hangover by chlormethiazole
    • Myrsten AL, Rydberg U, Ideström CM, Lamble R. Alcohol intoxication and hangover: modification of hangover by chlormethiazole. Psychopharmacology (Berl). 1980;69:117-25. (Pubitemid 10069531)
    • (1980) Psychopharmacology , vol.69 , Issue.2 , pp. 117-125
    • Myrsten, A.L.1    Rydberg, U.2    Idestrom, C.M.3    Lamble, R.4
  • 135
    • 0019297396 scopus 로고
    • Effects of ethanol on the developing rat. I. Ethanol metabolism and effects on lactate, pyruvate, and glucose concentrations
    • Hollstedt C, Rydberg U, Olsson O, Buijten J. Effects of ethanol on the developing rat. I. Ethanol metabolism and effects on lactate, pyruvate, and glucose concentrations. Med Biol. 1980; 58:158-63. (Pubitemid 11161878)
    • (1980) Medical Biology , vol.58 , Issue.3 , pp. 158-163
    • Hollstedt, C.1    Rydberg, U.2    Olsson, O.3    Buijten, J.4
  • 136
    • 0031466668 scopus 로고    scopus 로고
    • Low-molecular-weight metabolites relevant to ethanol metabolism: Correlation with alcohol withdrawal severity and utility for identification of alcoholics
    • Pronko PS, Velichko MG, Moroz AR, Rubanovich NN. Lowmolecular- weight metabolites relevant to ethanol metabolism: correlation with alcohol withdrawal severity and utility for identification of alcoholics. Alcohol Alcohol. 1997;32:761-8. (Pubitemid 28006016)
    • (1997) Alcohol and Alcoholism , vol.32 , Issue.6 , pp. 761-768
    • Pronko, P.S.1    Velichko, M.G.2    Moroz, A.R.3    Rubanovich, N.N.4
  • 137
  • 138
    • 0026320456 scopus 로고
    • Concentrations of blood and urine ethanol, acetaldehyde, acetate and acetone during experimental hangover in volunteers
    • Tskuamoto S, Kanegae T, Saito M, et al. Concentrations of blood and urine ethanol, acetaldehyde, acetate and acetone during experimental hangover in volunteers. Arukoru Kenkyuto Yakubutsu Ison. 1991;26:500-10.
    • (1991) Arukoru Kenkyuto Yakubutsu Ison , vol.26 , pp. 500-10
    • Tskuamoto, S.1    Kanegae, T.2    Saito, M.3
  • 139
    • 12244289642 scopus 로고    scopus 로고
    • Pyruvate dehydrogenase complex: Metabolic link to ischemic brain injury and target of oxidative stress
    • DOI 10.1002/jnr.20293, Brain Energy Metabolism: Transporters, Mitochondria and Neurodegeneration
    • Martin E, Rosenthal RE, Fiskum G. Pyruvate dehydrogenase complex: metabolic link to ischemic brain injury and target of oxidative stress. J Neurosci Res. 2005;79:240-7. (Pubitemid 40116441)
    • (2005) Journal of Neuroscience Research , vol.79 , Issue.1-2 , pp. 240-247
    • Martin, E.1    Rosenthal, R.E.2    Fiskum, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.