Metabolic failure precedes intracranial pressure rises in traumatic brain injury: A microdialysis study

Acta Neurochirurgica

Volumn 150, Issue 5, 2008, Pages 461-469

  Belli, A ^a,d   Sen, J ^b   Petzold, A ^c   Russo, S ^b   Kitchen, N ^b   Smith, M ^b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Glutamate; Glycerol; ICP; Lactate:pyruvate ratio; Microdialysis; Traumatic brain injury

Indexed keywords

BIOLOGICAL MARKER; GLUTAMIC ACID; GLYCEROL; LACTIC ACID; PYRUVIC ACID;

ADOLESCENT; ADULT; AGED; ARTICLE; BIOCHEMISTRY; BRAIN PERFUSION; CALCULATION; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONFIDENCE INTERVAL; CORRELATION ANALYSIS; HUMAN; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; METABOLIC DISORDER; MICRODIALYSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; TRAUMATIC BRAIN INJURY;

BIOLOGICAL MARKERS; BRAIN; BRAIN INJURIES; GLUTAMIC ACID; GLYCEROL; HUMANS; INTRACRANIAL HYPERTENSION; LACTIC ACID; METABOLIC DISEASES; MICRODIALYSIS; OSMOLAR CONCENTRATION; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PYRUVIC ACID; RISK FACTORS;

EID: 43549092825     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-008-1580-3     Document Type: Article

References (44)

1. (1996) Guidelines for the management of severe head injury. Brain Trauma Foundation, American Association of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care. J Neurotrauma 13: 641-734
2. A Belli J Sen A Petzold S Russo N Kitchen M Smith B Tavazzi R Vagnozzi S Signoretti AM Amorini F Bellia G Lazzarino 2006 Extracellular N-acetylaspartate depletion in traumatic brain injury J Neurochem 96 861 869
3. SL Budd DG Nicholls 1996 Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells J Neurochem 67 2282 2291
4. T Clausen OL Alves M Reinert E Doppenberg A Zauner R Bullock 2005 Association between elevated brain tissue glycerol levels and poor outcome following severe traumatic brain injury J Neurosurg 103 233 238
5. C Dohmen E Kumura G Rosner WD Heiss R Graf 2005 Extracellular correlates of glutamate toxicity in short-term cerebral ischemia and reperfusion: a direct in vivo comparison between white and gray matter Brain Res 1037 43 51
6. G Fiskum 2004 Mechanisms of neuronal death and neuroprotection J Neurosurg Anesthesiol 16 108 110
7. G Fiskum AN Murphy MF Beal 1999 Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases J Cereb Blood Flow Metab 19 351 369
8. L Hillered L Ernster 1983 Respiratory activity of isolated rat brain mitochondria following in vitro exposure to oxygen radicals J Cereb Blood Flow Metab 3 207 214
9. L Hillered L Persson 1999 Neurochemical monitoring of the acutely injured human brain Scand J Clin Lab Invest Suppl 229 9 18
10. L Hillered L Persson P Nilsson E Ronne-Engstrom P Enblad 2006 Continuous monitoring of cerebral metabolism in traumatic brain injury: a focus on cerebral microdialysis Curr Opin Crit Care 12 112 118
11. L Hillered ML Smith BK Siesjo 1985 Lactic acidosis and recovery of mitochondrial function following forebrain ischemia in the rat J Cereb Blood Flow Metab 5 259 266
12. L Hillered J Valtysson P Enblad L Persson 1998 Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain J Neurol Neurosurg Psychiatry 64 486 491
13. L Hillered PM Vespa DA Hovda 2005 Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis J Neurotrauma 22 3 41
14. Hutchinson PJ, al-Rawi PG, O'Connell MT, Gupta AK, Maskell LB, Hutchinson DB, Pickard JD, Kirkpatrick PJ (2000) On-line monitoring of substrate delivery and brain metabolism in head injury. Acta Neurochir (Suppl 76): 431-435
15. PJ Hutchinson AK Gupta TF Fryer PG Al-Rawi DA Chatfield JP Coles MT O'Connell R Kett-White PS Minhas FI Aigbirhio JC Clark PJ Kirkpatrick DK Menon JD Pickard 2002 Correlation between cerebral blood flow, substrate delivery, and metabolism in head injury: a combined microdialysis and triple oxygen positron emission tomography study J Cereb Blood Flow Metab 22 735 745
16. AJ Johnston AK Gupta 2002 Advanced monitoring in the neurology intensive care unit: microdialysis Curr Opin Crit Care 8 121 127
17. H Kim RC Koehler PD Hurn ED Hall RJ Traystman 1996 Amelioration of impaired cerebral metabolism after severe acidotic ischemia by tirilazad posttreatment in dogs Stroke 27 114 121
18. AI Maas M Dearden GM Teasdale R Braakman F Cohadon F Iannotti A Karimi F Lapierre G Murray J Ohman L Persson F Servadei N Stocchetti A Unterberg 1997 EBIC-guidelines for management of severe head injury in adults. European Brain Injury Consortium Acta Neurochir (Wien) 139 286 294
19. S Magnoni L Ghisoni M Locatelli M Caimi A Colombo V Valeriani N Stocchetti 2003 Lack of improvement in cerebral metabolism after hyperoxia in severe head injury: a microdialysis study J Neurosurg 98 952 958
20. N Marklund K Salci A Lewen L Hillered 1997 Glycerol as a marker for post-traumatic membrane phospholipid degradation in rat brain Neuroreport 8 1457 1461
21. DK Menon 1999 Cerebral protection in severe brain injury: physiological determinants of outcome and their optimisation Br Med Bull 55 226 258
22. PS Murphy MO Leach IJ Rowland 1999 Signal modulation in (1)H magnetic resonance spectroscopy using contrast agents: proton relaxivities of choline, creatine, and N-acetylaspartate Magn Reson Med 42 1155 1158
23. OG Nilsson L Brandt U Ungerstedt H Saveland 1999 Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration Neurosurgery 45 1176 1184 discussion 84-85
24. HC Patel DK Menon S Tebbs R Hawker PJ Hutchinson PJ Kirkpatrick 2002 Specialist neurocritical care and outcome from head injury Intensive Care Med 28 547 553
25. L Persson L Hillered 1992 Chemical monitoring of neurosurgical intensive care patients using intracerebral microdialysis J Neurosurg 76 72 80
26. S Rehncrona L Mela BK Siesjo 1979 Recovery of brain mitochondrial function in the rat after complete and incomplete cerebral ischemia Stroke 10 437 446
27. P Reinstrup N Stahl P Mellergard T Uski U Ungerstedt CH Nordstrom 2000 Intracerebral microdialysis in clinical practice: baseline values for chemical markers during wakefulness, anesthesia, and neurosurgery Neurosurgery 47 701 709 discussion 9-10
28. CS Robertson SP Gopinath M Uzura AB Valadka JC Goodman 1998 Metabolic changes in the brain during transient ischemia measured with microdialysis Neurol Res 20 Suppl 1 S91 S94
29. AS Sarrafzadeh OW Sakowitz KL Kiening G Benndorf WR Lanksch AW Unterberg 2002 Bedside microdialysis: a tool to monitor cerebral metabolism in subarachnoid hemorrhage patients? Crit Care Med 30 1062 1070
30. AF Schinder EC Olson NC Spitzer M Montal 1996 Mitochondrial dysfunction is a primary event in glutamate neurotoxicity J Neurosci 16 6125 6133
31. MK Schulz LP Wang M Tange P Bjerre 2000 Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage J Neurosurg 93 808 814
32. S Signoretti A Marmarou B Tavazzi G Lazzarino A Beaumont R Vagnozzi 2001 N-Acetylaspartate reduction as a measure of injury severity and mitochondrial dysfunction following diffuse traumatic brain injury J Neurotrauma 18 977 991
33. J Skjoth-Rasmussen M Schulz SR Kristensen P Bjerre 2004 Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage J Neurosurg 100 8 15
34. M Smith 2003 Diffuse axonal injury in adults Trauma 5 1 8
35. N Stahl P Mellergard A Hallstrom U Ungerstedt CH Nordstrom 2001 Intracerebral microdialysis and bedside biochemical analysis in patients with fatal traumatic brain lesions Acta Anaesthesiol Scand 45 977 985
36. AK Stout HM Raphael BI Kanterewicz E Klann IJ Reynolds 1998 Glutamate-induced neuron death requires mitochondrial calcium uptake Nat Neurosci 1 366 373
37. GM Teasdale DI Graham 1998 Craniocerebral trauma: protection and retrieval of the neuronal population after injury Neurosurgery 43 723 737 discussion 37-38
38. R Vagnozzi A Marmarou B Tavazzi S Signoretti D Di Pierro F del Bolgia AM Amorini G Fazzina S Sherkat G Lazzarino 1999 Changes of cerebral energy metabolism and lipid peroxidation in rats leading to mitochondrial dysfunction after diffuse brain injury J Neurotrauma 16 903 913
39. BH Verweij JP Muizelaar FC Vinas PL Peterson Y Xiong CP Lee 2000 Impaired cerebral mitochondrial function after traumatic brain injury in humans J Neurosurg 93 815 820
40. P Vespa M Bergsneider N Hattori HM Wu SC Huang NA Martin TC Glenn DL McArthur DA Hovda 2005 Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study J Cereb Blood Flow Metab 25 763 774
41. RJ White IJ Reynolds 1996 Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure J Neurosci 16 5688 5697
42. Y Xiong Q Gu PL Peterson JP Muizelaar CP Lee 1997 Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury J Neurotrauma 14 23 34
43. YH Yau IR Piper RE Clutton IR Whittle 2000 Experimental evaluation of the Spiegelberg intracranial pressure and intracranial compliance monitor. Technical note J Neurosurg 93 1072 1077
44. A Zauner WP Daugherty MR Bullock DS Warner 2002 Brain oxygenation and energy metabolism: part I - biological function and pathophysiology Neurosurgery 51 289 301 discussion 2