Cerebral microdialysis: Research technique or clinical tool

British Journal of Anaesthesia

Volumn 97, Issue 1, 2006, Pages 18-25

  Tisdall, M M ^a,b   Smith, Martin ^a,b  

^a NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Brain, injury; Metabolism, metabolites; Monitoring, intensive care; Monitoring, microdialysis

Indexed keywords

BIOLOGICAL MARKER; GLUCOSE; GLUTAMIC ACID; GLYCEROL; LACTIC ACID; PYRUVIC ACID;

BIOCHEMISTRY; BRAIN INJURY; BRAIN TISSUE; CATHETER; GLUCOSE METABOLISM; HEALTH CARE FACILITY; HUMAN; INTENSIVE CARE; LABORATORY TEST; MEDICAL RESEARCH; MEDICAL SPECIALIST; MICRODIALYSIS; MONITOR; NONHUMAN; ONLINE ANALYSIS; PATIENT MONITORING; PRIORITY JOURNAL; REVIEW;

EID: 33745684731     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/ael109     Document Type: Review

References (59)

1. Abi-Saab WM, Maggs DG, Jones T, et al. Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: Effects of hyperglycaemia and hypoglycaemia. J Cereb Blood Flow Metab 2002; 22: 271-9
2. Bellander BM, Cantais E, Enblad P, et al. Consensus meeting on microdialysis in neurointensive care. Intensive Care Med 2004; 30: 2166-9
3. Belli A, Sen J, Petzold A, et al. Extracellular N-acetylaspartate depletion in traumatic brain injury. J Neurochem 2006; 96: 861-9
4. Benveniste H, Drejer J, Schousboe A, Diemer NH. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischaemia monitored by intracellular microdialysis. J Neurochem 1984; 43: 1369-74
5. Benveniste H, Huttemeir PC. Microdialysis-theory and application. Prog Neurobiol 1990; 35: 195-215
6. Bergsneider MA, Hovda DA, Shalmon E, et al. Cerebral hyperglycolysis following severe human traumatic brain injury: A positron emission tomography study. J Neurosurg 1997; 86: 241-51
7. Bito L, Davson H, Levin EM, Murray M, Snider N. The concentration of free amino acids and other electrolytes in cerebrospinal fluid in vivo dialysate of brain blood plasma of the dog. J Neurochem 1966; 13: 1057-67
8. 2 for neuro-monitoring before decompressive craniectomy. Acta Anaesthesiol Scand 2006; 50: 252-4
9. Clausen T, Alves OL, Reinert M, Doppenberg E, Zauner A, Bullock R. Association between elevated tissue glycerol levels and poor outcome following severe traumatic brain injury. J Neurosurg 2005; 103: 233-8
10. Delgado JM, DeFeudis FV, Roth RH, Ryugo DK, Mitruka BM. Dialytrode for long term intracerebral perfusion in awake monkeys. Arch Int Pharmacodyn Ther 1972; 198: 9-21
11. Enblad P, Valtysson J, Andersson J, et al. Simultaneous intracerebral microdialysis and positron emission tomography in the detection of ischemia in patients with subarachnoid hemorrhage. J Cereb Blood Flow Metab 1996; 16: 637-44
12. Engstrom M, Polito A, Reinstrup P, et al. Intracerebral microdialysis in severe brain trauma: The importance of catheter location. J Neurosurg 2005; 102: 460-9
13. Goodman JC, Valadka AB, Gopinath SP, Uzura M, Robertson CS. Extracellular lactate and glucose alterations in the brain after head injury measured by microdialysis. Crit Care Med 1999; 27: 1965-73
14. Hillered L, Vespa PM, Hovda DA. Translational neurochemical research in acute human brain injury: The current status and potential future for cerebral microdialysis. J Neurotrauma 2005; 22:3-41
15. Hlatky R, Valadka A, Goodman J, Robertson C. Evolution of brain tissue injury after evacuation of acute traumatic subdural haematoma. Neurosurgery 2004; 55: 1318-23
16. Hovda DA, Yoshino A, Kawamata T, Katayama Y, Becker D. Diffuse prolonged depression of cerebral oxidative metabolism following concussive brain injury in the rat: A cytochrome oxidase histochemistry study. Brain Res 1991; 3: 1-10
17. Hutchinson PJ, Al-Rawi PG, O'Connell MT, et al. On-line monitoring of substrate delivery and brain metabolism in head injury. Acta Neurochir Suppl 2000; 76: 431-5
18. Hutchinson PJ, Gupta AK, Frywe TF, et al. Correlation between cerebral blood flow, substrate delivery, and metabolism in head injury: A combined microdialysis and triple oxygen positron emission tomography study. J Cereb Blood Flow Metab 2002; 22: 735-45
19. Hutchinson PJ, O'Connell MT, Nortje J, et al. Cerebral microdialysis methodology - evaluation of 20 kDa and 100 kDa catheters. Physiol Meas 2005; 26: 423-8
20. Jeremitsky E, Omert LA, Dunham CM, Wilberger J, Rodriguez A. The impact of hyperglycemia on patients with severe brain injury. J Neurotrouma 2005; 58: 47-50
21. Johnston AJ, Steiner LA, Coles JP, et al. Effect of cerebral perfusion pressure augmentation on regional oxygenation and metabolism after head injury. Crit Care Med 2005; 33: 189-95
22. Kehr J. A survey on quantitative microdialysis: Theoretical models and practical implications. J Neurosci Methods 1993; 48: 251-61
23. Kett-White R, Hutchinson PJ, Al-Rawi PG, Gupta AK, Pickard JD, Kirkpatrick PJ. Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes. Neurosurgery 2002; 50: 1213-21
24. Langemann H, Mendelowitsch A, Landolt H, Alessandril B, Gratzl O. Experimental and clinical monitoring of glucose by microdialysis. Clin Neurol Neurosurg 1995; 97: 149-55
25. Lindefors N, Amberg G, Ungerstedt U. Intracerebral microdialysis: I. Experimental studies of diffusion kinetics. J Pharmacol Methods 1989; 22: 141-56
26. Marion DW, Puccio A, Wisniewski SR, et al. Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury. Crit Care Med 2002; 30: 2619-25
27. Maurer MH, Berger C, Wolf M, et al. The proteome of human brain microdialysate. Proteome Sci 2003; 1: 7
28. Nilsson OG, Brandt L, Ungerstedt U, Saveland H. Bedside detection of brain ischemia using intracerebral microdialysis: Subarachnoid hemorrhage and delayed ischemic deterioration. Neurosurgery 1999; 45: 1176-84
29. Nilsson P, Hillered L, Porten U, Ungerstedt U. Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats. J Cereb Blood Flow Metab 1990; 10: 631-7
30. Nordstrom C, Reinstrup P, Xu W, Gardenfors A, Ungerstedt U. Assessment of lower limit for cerebral perfusion pressure in severe head injuries by bedside monitoring of regional energy metabolism. Anesthesiology 2003; 98: 809-14
31. Obrenovitch TP, Urenjak J. Is high extracellular glucamate the key to excitotoxicity in traumatic brain injury? J Neurotrauma 1997; 14: 677-98
32. Peerdeman SM, Girbes AR, Polderman KH, Vandertop W. Changes in interstitial glycerol concentration in head-injured patients: correlation with clinical events. Intensive Care Med 2003; 29: 1825-8
33. Persson L, Hillered L Intracerebral microdialysis. J Neurosurg 1996; 85: 984-5
34. Persson L, Hillered L. Chemical monitoring of neurosurgical intensive care patients using intracerebral microdialysis. J Neurosurg 1992; 76: 72-80
35. Persson L, Valtysson J, Enblad P, et al. Neurochemical monitoring using intracerebral microdialysis in patients with subarachnoid hemorrhage. J Neurosurg 1996; 84: 606-16
36. Redgate ES, Boggs S, Grudziak A, Deutsch M. Polyamines in brain tumour therapy. J Neurooncol 1995; 25: 167-79
37. Reinstrup P, Stahl N, Mellergard P, Uski T, Ungerstedt U, Nordstrom CH. Intracerebral microdialysis in clinical practice: Baseline values for chemical markers during wakefulness, anesthesia, and neurosurgery. Neurosurgery 2000; 47: 701-9
38. Robertson CS, Gopinath SP, Uzura M, Valadka AB, Goodman JC. Metabolic changes in the brain during transient ischemia measured with microdialysis. Neurol Res 1998; 20 (Suppl. 1): 91-4
39. Ronquist G, Hugosson R, Sjolander U, Ungerstedt U. Treatment of malignant glioma by a new therapeutic principle. Acta Neurochir (Wien) 1992; 114: 8-11
40. Sakowitz OW, Wolfrum S, Sarrafzadeh AS, Stover JF, Lanksch WR, Unterberg AW. Temporal profiles of extracellular nitric oxide metabolites following aneurysmal subarachnoid hemorrhage. Acta Neurochir (Wien) 2002; 581: 351-4
41. Sarrafzadeh A, Haux D, Kuchler I, Lanksch WR, Unterberg AW. Poor-grade aneurysmal subarachnoid hemorrhage: Relationship of cerebral metabolism to outcome. J Neurosurg 2004; 100: 400-6
42. Sarrafzadeh AS, Haux D, Ludemann L, et al. Cerebral ischemia in aneurysmal subarachnoid hemorrhage: A correlative microdialysis-PET study. Stroke 2004; 35: 638-43
43. Schulz M, Wang L, Tange M, Bjerre P. Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg 2000; 93: 233-8
44. Sen J, Belli A, Petzold A, et al. Extracellular fluid S100B in the injured brain: A future surrogate marker of acute brain injury? Acta Neurochir (Wien) 2005; 147: 897-900
45. Siesjo BK. Cerebral circulation and metabolism. J Neurosurg 1984; 60: 883-908
46. Skjoth-Rasmussen J, Schulz M, Kristensen SR, Bjerre P. Delayed neurological deficit detected by an ischemic pattern in the extracellular metabolites in patients with aneurismal subarachnoid hemorrhage. J Neurosurg 2004; 100: 8-15
47. Smith M, Belli A, Sen J, Russo S, Petzold A, Kitchen N. Prediction of secondary brain injury during neurocritical care: The role of cerebral microdialysis. In: Klaus S, Bahlmann L, eds. Microdialysis - Monitoring Tissue Chemistry in Intensive Care Medicine. Lengerich: Pabst Science Publishers, 2004; 45-55
48. Smith M. EditoHial 1: Neurocritical care: has it come of age? Br J Anaesth 2004; 93: 753-5
49. Stahl N, Mellergard P, Hallstrom A, Ungerstedt U, Nordstrom CH. Intracerebral microdialysis and bedside biochemical analysis in patients with fatal traumatic brain lesions. Acta Anaesthesiol Scand 2001; 45: 977-85
50. Teasdale G.M., Graham DI. Craniocerebral trauma: Protection and retrieval of the neuronal population after injury. Neurosurgery 1998; 43: 723-38
51. Ungerstedt U. Measurement of neurotransmitter release by intracranial microdialysis. In: Marsden CA, ed. Measurement of Neurotransmitter Release In Vivo. Chichester Wiley, 1984; 81-105
52. Ungerstedt U, Pycock C. Functional correlates of dopamine neurotransmission. Bull Schweiz Akad Med Wiss 1974; 30: 44-55
53. Unterberg AW, Sakowitz OW, Sarrafzadeh AS, Benndorf G, Lanksch WR. Role of bedside microdialysis in the diagnosis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg 2001; 94: 740-9
54. Valadka AB, Goodman JC, Gopinath SP, Uzura M, Robertson CS. Comparison of brain tissue oxygen tension to microdialysis-based measures of cerebral ischemia in fatally head-injured humans. J Neurotrauma 1998; 15: 509-19
55. Vespa P, Martin NA, Nenov V, et al. Delayed increase in extracellular glycerol with post-traumatic ellectrographic epileptic activity: Support for the theory that seizures induce secondary injury. Acta Neurochir Suppl 2002; 81: 355-7
56. Vespa PM, Boonyaputthikul R, McArthur DL, et al. Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury. Crit Care Med 2006; 34: 850-6
57. Vespa PM, McArthur D, O'Phelan K, et al. Persistently low extracellular glucose correlates with poor outcome 6 months after human traumatic brain injury despite a lack of increased lactate: A microdialysis study. J Cereb Blood Flow Metab 2003; 23: 865-77
58. Vespa P, Bergsneider M, Hattori N, et al. Metabolic crisis without brain ischemia is common after traumatic brain injury: A combined microdialysis and positron emission tomography study. J Cereb Blood Flow Metab 2005; 25: 763-74
59. Zauner A, Doppenberg E, Woodward J, Choi S, Young H, Bullock R. Continuous monitoring of cerebral substrate delivery and clearance: initial experience in 24 patients with severe acute brain injuries. Neurosurgery 1997; 41: 1082-93