Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis

Critical Care Medicine

Volumn 35, Issue 12, 2007, Pages 2830-2836

  Vespa, Paul M ^a,b   Miller, Chad ^a,b   McArthur, David ^a   Eliseo, Mathew ^a   Etchepare, Maria ^a   Hirt, Daniel ^a   Glenn, Thomas C ^a   Martin, Neil ^a   Hovda, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Continuous electroencephalography; Intensive care; Intracranial pressure; Lactate; Microdialysis; Nonconvulsive; Pyruvate; Seizures; Status epilepticus; Traumatic brain injury

Indexed keywords

LACTIC ACID; PYRUVIC ACID;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; EPILEPTIC STATE; EPILEPTOGENESIS; GLASGOW COMA SCALE; HUMAN; INJURY SCALE; INTENSIVE CARE UNIT; INTRACRANIAL PRESSURE; METABOLIC DISORDER; MICRODIALYSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; SEIZURE; TRAUMATIC BRAIN INJURY;

EID: 36448969810     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000295667.66853.BC     Document Type: Article

References (20)

1. Vincent JL, Berre J: Primer on medical management of severe brain injury. Crit Care Med 2005; 33:1392-1399
2. Vespa PM, Nuwer MR, Nenov V, et al: Increased incidence and impact of nonconvulsive and convulsive seizures after traumatic brain injury as detected by continuous EEG in the intensive care unit. J Neurosurg 1999; 91:750-760
3. Claassen J, Mayer SA, Kowalski RG, et al: Detection of electrographic seizures with continuous EEG monitoring in critically ill patients. Neurology 2004; 62:1743-1748
4. Vespa P, O'Phelan K, Mirabelli J, et al: Acute seizures after intracerebral hemorrhage: A factor in progressive midline shift and outcome. Neurology 2003; 60:1441-1446
5. Bergsneider MA, Hovda DA, Shalmon E, et al: Cerebral hyperglycolysis following severe human traumatic brain injury: A positron emission tomography study. J Neurosurg 1997; 86:241-251
6. Roncati Zanier E, Lee SM, Vespa PM, et al: Increased hippocampal CA3 vulnerability to low-level glutamate analogue following lateral fluid percussion injury. J Neurotrauma 2003; 20:409-420
7. Vespa P, Prins M, Ronne-Engstrom E, et al: Increase in extracellular glutamate caused by reduced cerebral perfusion pressure and seizures after human traumatic brain injury: A microdialysis study. J Neurosurg 1998; 89:971-982
8. Annegers JF, Grabow JD, Groover RV, et al: Seizures after head trauma: A population study. Neurology 1980; 30:683-689
9. Jennet WB, Lewin W: Traumatic epilepsy after closed head injuries. J Neurol Neurosurg Psychiatry 1980; 23:295-301
10. Lee ST, Wong CW, Yeh YS, et al: Early seizures after moderate closed head injury. Acta Neurochir 1995; 137:151-154
11. Temkin NR: Prophylactic anticonvulsants after neurosurgery. Epilepsy Curr 2002; 2:105-107
12. Vespa P: EEG for the detection of seizures in traumatic brain injury, infarction, and intracerebral hemorrhage: "To detect and protect." J Clin Neurophysiol 2005; 20:99-106
13. Parkin M, Hopwood S, Jones DA, et al: Dynamic changes in brain glucose and lactate in pericontusional areas of the human cerebral cortex, monitored with rapid sampling on-line microdialysis: Relationship with depolarisation-like events. J Cereb Blood Flow Metab 2005; 25:402-413
14. Enblad P, Valtysson J, Andersson J, et al: Simultaneous intracerebral microdialysis and positron emission tomography in the detection of ischemia in patients with sub-arachnoid hemorrhage. J Cereb Blood Flow Metab 1996; 16:637-644
15. Hoover RC, Motta M, Davis J, et al: Differential effects of the anticonvulsant topiramate on neurobehavioral and histological outcomes following traumatic brain injury in rats. J Neurotrauma 2004; 21:501-512
16. Hillered L, Vespa PM, Hovda DA: Translational neurochemical research in acute human brain injury: The current status and potential future for cerebral microdialysis. J Neurotrauma 2005; 22:3-41
17. Enblad P, Frykholm P, Valtysson J, et al: Middle cerebral artery occlusion and reperfusion in primates monitored by microdialysis and sequential positron emission tomography. Stroke 2001; 32:1574-1580
18. Vespa P, McArthur D, Glenn T, et al: Persistently reduced levels of extracellular glucose early after traumatic brain injury correlate with poor outcome at six months: A microdialysis study. J Cereb Blood Flow Metab 2003; 23:865-877
19. Vespa P, Bergsneider M, Hattori N, et al: Metabolic crisis without brain ischemia is common after traumatic brain injury: A combined microdialysis and positron emission tomography study. J Cereb Blood Flow Metab 2005; 25:763-774
20. Williams AJ, Tortella FC, Lu XM, et al: Anti-epileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. J Pharmacol Exp Ther 2004; 311:220-227