Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury

Critical Care Medicine

Volumn 36, Issue 10, 2008, Pages 2871-2877

  Marcoux, Judith ^b   McArthur, David A ^a   Miller, Chad ^a   Glenn, Thomas C ^a   Villablanca, Pablo ^a   Martin, Neil A ^a   Hovda, David A ^a   Alger, Jeffry R ^a   Vespa, Paul M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Atrophy; Biomarker; Brain trauma; Lactate; Microdialysis; MRI; Outcome; Pyruvate

Indexed keywords

GLUCOSE; GLUTAMIC ACID; GLYCEROL; LACTIC ACID; PYRUVIC ACID; BIOLOGICAL MARKER;

ADULT; ANASTOMOSIS; ARTICLE; BRAIN ATROPHY; BRAIN MICRODIALYSIS; BRAIN TISSUE; CLINICAL ARTICLE; CRANIOTOMY; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; FEMALE; FRONTAL LOBE; FRONTAL LOBE BRAIN ATROPHY; GLASGOW COMA SCALE; GLUCOSE BLOOD LEVEL; GLYCEROL BLOOD LEVEL; HUMAN; INTENSIVE CARE UNIT; LACTATE BLOOD LEVEL; LONG TERM CARE; MALE; METABOLIC DISORDER; MICRODIALYSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PATIENT MONITORING; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; TRAUMATIC BRAIN INJURY; VOLUMETRY; ADOLESCENT; ATROPHY; BRAIN DISEASE; BRAIN INJURY; CHRONIC DISEASE; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CRITICAL ILLNESS; FOLLOW UP; INJURY SCALE; METHODOLOGY; MIDDLE AGED; MORTALITY; PATHOLOGY; PREDICTION AND FORECASTING; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; ATROPHY; BIOLOGICAL MARKERS; BRAIN DISEASES; BRAIN INJURIES; CHRONIC DISEASE; COHORT STUDIES; CRITICAL ILLNESS; FEMALE; FOLLOW-UP STUDIES; FRONTAL LOBE; GLASGOW COMA SCALE; HUMANS; INJURY SEVERITY SCORE; INTENSIVE CARE UNITS; LACTIC ACID; MALE; MICRODIALYSIS; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PYRUVIC ACID; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 54549089085     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318186a4a0     Document Type: Article

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