Influence of adrenergic agonists on the release of amino acids from rat skeletal muscle studied by microdialysis

Acta Physiologica Scandinavica

Volumn 163, Issue 4, 1998, Pages 349-360

  Rosdahl, H ^a,b   Samuelsson, A C ^a   Ungerstedt, U ^a   Henriksson, J ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SWEDISH SCHOOL OF SPORT AND HEALTH SCIENCES   (Sweden)

Author keywords

Adrenaline; Amino acids; Blood flow; Ethanol; Microdialysis; Skeletal muscle

Indexed keywords

ADRENALIN; ADRENERGIC RECEPTOR STIMULATING AGENT; AMINO ACID; GLUTAMINE; ISOPRENALINE; LACTIC ACID; PYRUVIC ACID; VASOPRESSIN;

ADRENERGIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; VASOCONSTRICTION; VASODILATATION;

EID: 0031903645     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1998.t01-1-00341.x     Document Type: Article

References (29)

1. 2+ -mobilizing hormones serotonin, vasopressin, and bradykinin increase mitochondrially bound hexokinase in muscle. Biochem Med Metab Biol 41, 181-188.
2. Bernt, E. & Gutmann, I. 1974. Determination with alcohol dehydrogenase and NAD. In: H.U. Bergmeyer (ed.) Methods of Enzymatic Analysis., pp. 1499-1505. Verlag Chemie GmbH, Weinheim, FRG.
3. Del Prato, S., DeFronzo, R.A., Castellino, P., Wahren, J. & Alvestrand, A. 1990. Regulation of amino acid metabolism by epinephrine. Am J Physiol 258 (21), E878-E887.
4. 2O. Biochemistry of Exercise, 10th International Conference, Sydney, Australia (Abstract).
5. Ejesson, B., Lind, C., Vinnars, E. & Wernerman, J. 1990. Stress hormones initiates changes in muscle free amino acid concentrations characteristic for surgical trauma. Clin Nutr 9 (Spec Suppl.), 12.
6. Essén, P., Wernerman, J., Sonnenfeld, T., Thunell, S. & Vinnars, E. 1992. Free amino acids in plasma and muscle during 24 hours post-operatively- a descriptive study. Clin Physiol 12 (2), 163-177.
7. Ezrailson, E.G., Entman, M.L. & Garber, A.J. 1983. Adrenergic and serotonergic regulation of skeletal muscle metabolism in rat. J Biol Chem 258, 12494-12498.
8. Felig, P. 1975. Amino acid metabolism in man. Annu Rev Biochem 44, 933-955.
9. Fryburg, D.A., Gelfand, R.A., Jahn, L.A. et al. 1995. Effects of epinephrine on human muscle glucose and protein metabolism. Am J Physiol 268, E55-E59.
10. Garber, A.J., Karl, I.E. & Kipnis, D.M. 1976. Alanine and glutamine synthesis and release from skeletal muscle. IV. β-adrenergic inhibition of amino acid release. J Biol Chem 251, 851-857.
11. Goldberg, A.L. & Dice, J.F. 1974. Intracellular protein degradation in mammalian and bacterial cells. Annu Rev Biochem 43, 835-869.
12. Hallström, Å., Carlsson, A., Hillered, L. & Ungerstedt, U. 1989. Simultaneous determination of lactate, pyruvate, and ascorbate in microdialysis samples from rat brain, blood, fat, and muscle using high-performance liquid chromatography. J Pharmacol Meth 22, 113-124.
13. Hickner, R.C., Ekelund, U., Mellander, S., Ungerstedt, U. & Henriksson, J. 1995. Muscle blood flow in cats: comparison of the microdialysis ethanol technique with direct measurement. J Appl Physiol 79, 638-647.
14. Hickner, R.C., Rosdahl, H., Borg, I., Ungerstedt, U., Jorfeldt, L. & Henriksson, J. 1992. The ethanol technique of monitoring blood flow changes in rat skeletal muscle: implications for microdialysis. Acta Physiol Scand 146 (1), 87-97.
15. Larsson, J. & Hultman, E. 1979. The effect of long-term arterial occlusion on energy metabolism of the human quadriceps muscle. Scand J Clin Lab Invest 39, 257-264.
16. Li, J.B. & Jefferson, L.S. 1977. Effect of isoproterenol on amino acid levels and protein turnover in skeletal muscle. Am J Physiol 232 (2), E243-E249.
17. Liggett, S.B. & Raymond, J.R. 1993. Pharmacology and molecular biology of adrenergic receptors. Baillier̀e's Clin Endocrinol Metabolism 7, 279-306.
18. Lindroth, P. & Mopper, K. 1979. High performance liquid chromatograph determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with o-phthaldialdehyde. Anal Chem 51, 1667-1674.
19. Lund, J., Stjernström, H., Bergholm, U., jorfeldt, L., Vinnars, E. & Wiklund, L. 1986. The exchange of blood-borne amino acids in the leg during abdominal surgical trauma: effects of glucose infusion,.Clin Sci 71, 487-496.
20. Matthews, D.E., Pesola, G. & Campbell, R.G. 1990. Effect of epinephrine on amino acid and energy metabolism in humans. Am J Physiol 258 (21), E948-E956.
21. Miles, J.M., Nissen, S.L., Gerich, J.E. & Haymond, M.W. 1984. Effects of epinephrine infusion on leucine and alanine kinetics in humans. Am J Physiol 247, E166-E172.
22. Nie, Z.T., Wallberg-Henriksson, H., Johansson, S. & Henriksson, J. 1989. Effects of adrenaline and prior exercise on the release of alanine, glutamine and glutamate from incubated rat skeletal muscle. Acta Physiol Scand 136, 395-401.
23. Ruderman, N.B. 1975. Muscle amino acid metabolism and gluconeogenesis. Annu Rev Med 26, 245-258.
24. Svedenhag, J. 1994. Opposite effects of adrenaline on plasma ammonia and blood lactate concentrations in healthy men. Biochemistry of Eexercise. Ninth International Conference, Aberdeen 21-26 July (Abstract).
25. Tossman, U. & Ungerstedt, U. 1986. Microdialysis in the study of extracellular levels of amino acids in the rat brain. Acta Physiol Scand 128, 9-14.
26. Webber, J. & Macdonald, I.A. 1993. A comparison of the cardiovascular and metabolic effects of incremental versus continuous dose adrenaline infusions in men and women. Int J Obesity 17, 37-43.
27. Wernerman, J., Brandt, R., Strandell, T., Allgén, L.-G. & Vinnars, E. 1985. The effect of stress hormones on the interorgan flux of amino acids and on the concentration of free amino acids in skeletal muscle. Clin Nutr 4, 207-216.
28. Wernerman, J., Hammarqvist, F., Botta, D. & Vinnars, E. 1993. Stress hormones alter the pattern of free amino acids in human skeletal muscle. Clin Physiol 13, 309-319.
29. Williams, I.H., Sugden, P.H. & Morgan, H.E. 1981. Use of aromatic amino acids as monitors of protein turnover. Am J Physiol 240, E677-E681.