Protease activated receptor-1 inhibits the Maspin tumor-suppressor gene to determine the melanoma metastatic phenotype

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 2, 2011, Pages 626-631

  Villares, Gabriel J ^a   Zigler, Maya ^a   Dobroff, Andrey S ^a   Wang, Hua ^a   Song, Renduo ^a   Melnikova, Vladislava O ^a   Huang, Li ^a   Braeuer, Russell R ^a   Bar Eli, Menashe ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

G protein coupled receptor signaling; Melanoma progression; Serpin B5; Transcriptional regulation

Indexed keywords

MASPIN; PROTEIN C JUN; PROTEINASE ACTIVATED RECEPTOR 1; TRANSCRIPTION FACTOR ETS 1;

ARTICLE; CANCER GROWTH; CANCER INVASION; CELL INVASION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LUNG METASTASIS; MELANOMA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN TARGETING; REGULATORY MECHANISM; TRANSCRIPTION REGULATION;

ANIMALS; CHROMATIN; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; LUNG NEOPLASMS; MELANOMA; MICE; MICE, NUDE; NEOPLASM METASTASIS; PHENOTYPE; PROTO-ONCOGENE PROTEIN C-ETS-1; PROTO-ONCOGENE PROTEINS C-JUN; RECEPTOR, PAR-1; RECEPTORS, G-PROTEIN-COUPLED; SERPINS; SIGNAL TRANSDUCTION;

EID: 79551678748     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1006886108     Document Type: Article

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