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Volumn 93, Issue 4, 2011, Pages 312-323

Disruption of embryonic vascular development in predictive toxicology

Author keywords

Adverse outcome pathway; Angiogenesis; Developmental toxicity; Predictive toxicology; Vascular development

Indexed keywords

CHEMOKINE; CIGARETTE SMOKE; DIOXIN; ENDOTHELIN; ESTRADIOL; ESTROGEN; G PROTEIN COUPLED RECEPTOR; METAL; PLASMINOGEN ACTIVATOR; PLATELET DERIVED GROWTH FACTOR B; RETINOID; THALIDOMIDE; TRANSFORMING GROWTH FACTOR BETA; VASCULAR TARGETING AGENT; VASCULOTROPIN A;

EID: 84856241088     PISSN: 1542975X     EISSN: 15429768     Source Type: Journal    
DOI: 10.1002/bdrc.20223     Document Type: Review
Times cited : (76)

References (77)
  • 1
    • 0033662205 scopus 로고    scopus 로고
    • Placental defects in ARNT-knockout conceptus correlate with localized decreases in VEGF-R2, Ang-1, and Tie-2
    • Abbott BD and Buckalew AR. 2000. Placental defects in ARNT-knockout conceptus correlate with localized decreases in VEGF-R2, Ang-1, and Tie-2. Devel Dyn 219: 526-538.
    • (2000) Devel Dyn , vol.219 , pp. 526-538
    • Abbott, B.D.1    Buckalew, A.R.2
  • 2
    • 0035876321 scopus 로고    scopus 로고
    • Assembly of trunk and limb blood vessels involves extensive migration and vasculogenesis of somite-derived angioblasts
    • Ambler CA, Nowicki JL, Burke AC and Bautch V. (2001). Assembly of trunk and limb blood vessels involves extensive migration and vasculogenesis of somite-derived angioblasts. Dev Biol 234: 352-364.
    • (2001) Dev Biol , vol.234 , pp. 352-364
    • Ambler, C.A.1    Nowicki, J.L.2    Burke, A.C.3    Bautch, V.4
  • 3
    • 77951118386 scopus 로고    scopus 로고
    • Adverse outcome pathway: A conceptual framework to support ecotoxicology and risk assessment
    • Ankley GT, Bennett RS, Erickson RJ, et al. 2010. Adverse outcome pathway: A conceptual framework to support ecotoxicology and risk assessment. Environ Toxicol Chem 29: 730-741.
    • (2010) Environ Toxicol Chem , vol.29 , pp. 730-741
    • Ankley, G.T.1    Bennett, R.S.2    Erickson, R.J.3
  • 4
    • 77950361117 scopus 로고    scopus 로고
    • Effects of neonatal exposure to bisphenol a on steroid regulation of vascular endothelial growth factor expression and endothelial cell proliferation in the adult rat uterus
    • Bosquiazzo VL, Varayoud J, Muñoz-de-Toro M, et al. 2010. Effects of neonatal exposure to bisphenol a on steroid regulation of vascular endothelial growth factor expression and endothelial cell proliferation in the adult rat uterus. Biol Reprod 82: 86-95.
    • (2010) Biol Reprod , vol.82 , pp. 86-95
    • Bosquiazzo, V.L.1    Varayoud, J.2    Muñoz-de-Toro, M.3
  • 5
    • 79957619706 scopus 로고    scopus 로고
    • Microvascular mural cell functionality of human embryonic stem cell-derived mesenchymal cells
    • Boyd NL, Nunes SS, Jokinen JD, et al. 2011. Microvascular mural cell functionality of human embryonic stem cell-derived mesenchymal cells. Tissue Eng Part A 17: 1537-1548.
    • (2011) Tissue Eng Part A , vol.17 , pp. 1537-1548
    • Boyd, N.L.1    Nunes, S.S.2    Jokinen, J.D.3
  • 6
    • 34248593493 scopus 로고    scopus 로고
    • Effects of some endocrine disruptors on the proliferation and viability of human endometrial endothelial cells in vitro
    • Bredhult C, Bäcklin B-M, Olovsson M. 2007. Effects of some endocrine disruptors on the proliferation and viability of human endometrial endothelial cells in vitro. Reprod Toxicol 23: 550-559.
    • (2007) Reprod Toxicol , vol.23 , pp. 550-559
    • Bredhult, C.1    Bäcklin, B.-M.2    Olovsson, M.3
  • 7
    • 84866158884 scopus 로고    scopus 로고
    • Genetic causes of vascular malformations
    • 16 Spec No. 2
    • Brouillard PVikkula M. 2007. Genetic causes of vascular malformations. Hum Mol Genet 16 Spec No. 2: R140-R149.
    • (2007) Hum Mol Genet
    • Brouillard, P.1    Vikkula, M.2
  • 8
    • 34447252338 scopus 로고    scopus 로고
    • Refinement of a morphological scoring system for postimplantation rabbit conceptuses
    • Carney EW, Tornesi B, Keller C, et al. 2007. Refinement of a morphological scoring system for postimplantation rabbit conceptuses. Birth Defects Res B 80: 213-222.
    • (2007) Birth Defects Res B , vol.80 , pp. 213-222
    • Carney, E.W.1    Tornesi, B.2    Keller, C.3
  • 9
    • 38749128372 scopus 로고    scopus 로고
    • Visualization and experimental analysis of blood vessel formation using transgenic zebrafish
    • Cha YR, Weinstein BM. 2007. Visualization and experimental analysis of blood vessel formation using transgenic zebrafish. Birth Defects Res C 81: 286-296.
    • (2007) Birth Defects Res C , vol.81 , pp. 286-296
    • Cha, Y.R.1    Weinstein, B.M.2
  • 10
    • 80054012347 scopus 로고    scopus 로고
    • Developmental and pathological angiogenesis
    • Chung AS, Ferrara N. 2011. Developmental and pathological angiogenesis. Ann Rev Cell Dev Biol 27: 563-584.
    • (2011) Ann Rev Cell Dev Biol , vol.27 , pp. 563-584
    • Chung, A.S.1    Ferrara, N.2
  • 11
    • 39349118236 scopus 로고    scopus 로고
    • Transforming environmental health protection
    • Collins FS, Gray GM, Bucher JR. 2008. Transforming environmental health protection. Science 319: 906-907.
    • (2008) Science , vol.319 , pp. 906-907
    • Collins, F.S.1    Gray, G.M.2    Bucher, J.R.3
  • 12
    • 30744432619 scopus 로고    scopus 로고
    • Endothelial cells and VEGF in vascular development
    • Coultas L, Chawengsaksophak K, Rossant J. 2005. Endothelial cells and VEGF in vascular development. Nature 438: 937-945.
    • (2005) Nature , vol.438 , pp. 937-945
    • Coultas, L.1    Chawengsaksophak, K.2    Rossant, J.3
  • 14
    • 33845620001 scopus 로고    scopus 로고
    • The ToxCast program for prioritizing toxicity testing of environmental chemicals
    • Dix DJ, Houck KA, Martin MT, et al. 2007. The ToxCast program for prioritizing toxicity testing of environmental chemicals. Toxicol Sci 95: 5-12.
    • (2007) Toxicol Sci , vol.95 , pp. 5-12
    • Dix, D.J.1    Houck, K.A.2    Martin, M.T.3
  • 15
    • 40949107294 scopus 로고    scopus 로고
    • The genetics of vasculogenesis
    • Chadwick DJ, Goode J, editors. Hoboken: Wiley.
    • Drake CJ, Fleming PA, Argraves WS. 2007. The genetics of vasculogenesis. In: Chadwick DJ, Goode J, editors. Vascular development. Hoboken: Wiley. pp. 61-70.
    • (2007) Vascular development , pp. 61-70
    • Drake, C.J.1    Fleming, P.A.2    Argraves, W.S.3
  • 16
    • 0029015923 scopus 로고
    • Vascularization of the mouse embryo:a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development
    • Dumont DJ, Fong G-H, Puri MC, Gradwohl G, et al. 1995. Vascularization of the mouse embryo:a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev Dyn 203: 80-92.
    • (1995) Dev Dyn , vol.203 , pp. 80-92
    • Dumont, D.J.1    Fong, G.-H.2    Puri, M.C.3    Gradwohl, G.4
  • 17
    • 80053954482 scopus 로고    scopus 로고
    • Prenatal exposure to bisphenol A promotes angiogenesis and alters steroid-mediated responses in the mammary glands of cycling rats
    • Durando M, Kass L, Perdomo V, et al. 2011. Prenatal exposure to bisphenol A promotes angiogenesis and alters steroid-mediated responses in the mammary glands of cycling rats. J Steroid Bioch Mol Biol 127: 35-43.
    • (2011) J Steroid Bioch Mol Biol , vol.127 , pp. 35-43
    • Durando, M.1    Kass, L.2    Perdomo, V.3
  • 18
    • 73449145248 scopus 로고    scopus 로고
    • Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide
    • Ema M, Iseb R, Katoc H, Onedad S, Hirosea A, et al. 2010. Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide. Reprod Toxicol 29: 49-56.
    • (2010) Reprod Toxicol , vol.29 , pp. 49-56
    • Ema, M.1    Iseb, R.2    Katoc, H.3    Onedad, S.4    Hirosea, A.5
  • 19
    • 67650733297 scopus 로고    scopus 로고
    • The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf
    • Eshkar-Oren I, Viukov SV, Salameh S, et al. 2009. The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf. Development 136: 1263-1272.
    • (2009) Development , vol.136 , pp. 1263-1272
    • Eshkar-Oren, I.1    Viukov, S.V.2    Salameh, S.3
  • 20
    • 77956273530 scopus 로고    scopus 로고
    • Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction
    • Fantin A, Vieira JM, Gestri G, et al. 2010. Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood 116: 829-840.
    • (2010) Blood , vol.116 , pp. 829-840
    • Fantin, A.1    Vieira, J.M.2    Gestri, G.3
  • 21
    • 4544227785 scopus 로고    scopus 로고
    • Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice
    • Furuyama T, Kitayama K, Shimoda Y, et al. 2004. Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice. J Biol Chem 279: 34741-34749.
    • (2004) J Biol Chem , vol.279 , pp. 34741-34749
    • Furuyama, T.1    Kitayama, K.2    Shimoda, Y.3
  • 23
    • 0027536872 scopus 로고
    • Inhibition of angiogenesis by antiestrogens
    • Gagliardi A, Collins DC. 1993. Inhibition of angiogenesis by antiestrogens. Cancer Res 5: 533-535.
    • (1993) Cancer Res , vol.5 , pp. 533-535
    • Gagliardi, A.1    Collins, D.C.2
  • 24
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan D. 1997. Signaling vascular morphogenesis and maintenance. Science 277: 48-50.
    • (1997) Science , vol.277 , pp. 48-50
    • Hanahan, D.1
  • 25
    • 67650445156 scopus 로고    scopus 로고
    • Toxicology for the twenty-first century
    • Hartung T. 2009. Toxicology for the twenty-first century. Nature 460: 208-212.
    • (2009) Nature , vol.460 , pp. 208-212
    • Hartung, T.1
  • 26
    • 80052015813 scopus 로고    scopus 로고
    • Molecular control of endothelial cell behaviour during blood vessel Morphogenesis
    • Herbert SP and Stainier DYR. 2011. Molecular control of endothelial cell behaviour during blood vessel Morphogenesis. Nat Rev Mol Cell Biol 12: 551-564.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 551-564
    • Herbert, S.P.1    Stainier, D.Y.R.2
  • 27
    • 11144297756 scopus 로고    scopus 로고
    • Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice
    • Hiratsuka S, Nakao K, Nakamura K, et al. 2005. Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice. Mol Cell Biol 25: 346-354.
    • (2005) Mol Cell Biol , vol.25 , pp. 346-354
    • Hiratsuka, S.1    Nakao, K.2    Nakamura, K.3
  • 28
    • 0037401126 scopus 로고    scopus 로고
    • Proposal for a tiered approach to developmental toxicity testing for veterinary pharmaceutical products for food producing animals
    • Hurtt ME, Cappon GD, Browning A. 2003. Proposal for a tiered approach to developmental toxicity testing for veterinary pharmaceutical products for food producing animals. Food Chem Toxicol 41: 611-619.
    • (2003) Food Chem Toxicol , vol.41 , pp. 611-619
    • Hurtt, M.E.1    Cappon, G.D.2    Browning, A.3
  • 29
    • 33645833215 scopus 로고    scopus 로고
    • Suppressive effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on vascular remodeling that takes place in the normal labyrinth zone of rat placenta during late gestation
    • Ishimura R, Kawakami T, Ohsako S, et al. 2006. Suppressive effect of 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin on vascular remodeling that takes place in the normal labyrinth zone of rat placenta during late gestation. Toxicol Sci 91: 265-274.
    • (2006) Toxicol Sci , vol.91 , pp. 265-274
    • Ishimura, R.1    Kawakami, T.2    Ohsako, S.3
  • 30
    • 77949350034 scopus 로고    scopus 로고
    • Identification of a primary target of thalidomide teratogenicity
    • Ito T, Ando H, Suzuki T, et al. 2010. Identification of a primary target of thalidomide teratogenicity. Science 327: 1345-1350.
    • (2010) Science , vol.327 , pp. 1345-1350
    • Ito, T.1    Ando, H.2    Suzuki, T.3
  • 31
    • 77951675220 scopus 로고    scopus 로고
    • In vitro screening of environmental chemicals for targeted testing prioritization - the ToxCast project
    • Judson R, Houck KA, Kavlock RJ, et al. 2010. In vitro screening of environmental chemicals for targeted testing prioritization - the ToxCast project. Environ Health Perspect 118: 485-492.
    • (2010) Environ Health Perspect , vol.118 , pp. 485-492
    • Judson, R.1    Houck, K.A.2    Kavlock, R.J.3
  • 32
    • 0031351597 scopus 로고    scopus 로고
    • Vascular effects of endothelin-1 in stage 21 chick embryos
    • Kajio F, Nakazawa M, 1997. Vascular effects of endothelin-1 in stage 21 chick embryos. Heart Vessel 12: 300-305.
    • (1997) Heart Vessel , vol.12 , pp. 300-305
    • Kajio, F.1    Nakazawa, M.2
  • 33
    • 44649128099 scopus 로고    scopus 로고
    • The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching
    • Kappas NC, Zeng G, Chappell JC, et al. 2008. The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching. J Cell Biol 181: 847-858.
    • (2008) J Cell Biol , vol.181 , pp. 847-858
    • Kappas, N.C.1    Zeng, G.2    Chappell, J.C.3
  • 36
    • 67349147007 scopus 로고    scopus 로고
    • Small molecule screen for compounds that affect vascular development in the zebrafish retina
    • Kitambi SS, MaCulloch KJ, Peterson RT, Malicki JJ. 2009. Small molecule screen for compounds that affect vascular development in the zebrafish retina. Mech Dev 126: 464-477.
    • (2009) Mech Dev , vol.126 , pp. 464-477
    • Kitambi, S.S.1    MaCulloch, K.J.2    Peterson, R.T.3    Malicki, J.J.4
  • 37
    • 80053009778 scopus 로고    scopus 로고
    • Environmental impact on vascular development predicted by high-throughput screening
    • Kleinstreuer NC, Judson RS, Reif DM, et al. 2011. Environmental impact on vascular development predicted by high-throughput screening. Environ Health Perspect 119: 1596-1603.
    • (2011) Environ Health Perspect , vol.119 , pp. 1596-1603
    • Kleinstreuer, N.C.1    Judson, R.S.2    Reif, D.M.3
  • 38
    • 67650729693 scopus 로고    scopus 로고
    • Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB
    • Knudsen TB, Martin MT, Kavlock RJ, et al. 2009. Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB. Reprod Toxicol 28: 209-219.
    • (2009) Reprod Toxicol , vol.28 , pp. 209-219
    • Knudsen, T.B.1    Martin, M.T.2    Kavlock, R.J.3
  • 39
    • 80054691906 scopus 로고    scopus 로고
    • Developmental toxicity testing for safety assessment: New approaches and technologies
    • Knudsen TB, Kavlock RJ, Daston GP, et al. 2011. Developmental toxicity testing for safety assessment: New approaches and technologies. Birth Defects Res B 92: 413-420.
    • (2011) Birth Defects Res B , vol.92 , pp. 413-420
    • Knudsen, T.B.1    Kavlock, R.J.2    Daston, G.P.3
  • 40
    • 78149399666 scopus 로고    scopus 로고
    • Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124
    • Kuhnert F, Mancuso MR, Shamloo A, et al. 2010. Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124. Science 330: 985-989.
    • (2010) Science , vol.330 , pp. 985-989
    • Kuhnert, F.1    Mancuso, M.R.2    Shamloo, A.3
  • 41
    • 12344275640 scopus 로고    scopus 로고
    • Control of arterial branching morphogenesis in embryogenesis:go with the flow
    • Le Noble F, Fleury V, Pries A, et al. 2005. Control of arterial branching morphogenesis in embryogenesis:go with the flow. Cardiovasc Res 65: 61-28.
    • (2005) Cardiovasc Res , vol.65 , pp. 61-28
    • Le Noble, F.1    Fleury, V.2    Pries, A.3
  • 42
    • 77950538918 scopus 로고    scopus 로고
    • Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia
    • Lebrin F, Srun S, Raymon K, et al. 2010. Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia. Nat Med 16: 420-428.
    • (2010) Nat Med , vol.16 , pp. 420-428
    • Lebrin, F.1    Srun, S.2    Raymon, K.3
  • 43
    • 0034987783 scopus 로고    scopus 로고
    • Effects of the xenoestrogen bisphenol A on expression of vascular endothelial growth factor (VEGF) in the rat
    • Long X, Burke KA, Bigsby RM, Nephew KP. 2001. Effects of the xenoestrogen bisphenol A on expression of vascular endothelial growth factor (VEGF) in the rat. Exp Biol Med 226: 477-483.
    • (2001) Exp Biol Med , vol.226 , pp. 477-483
    • Long, X.1    Burke, K.A.2    Bigsby, R.M.3    Nephew, K.P.4
  • 44
    • 35548932510 scopus 로고    scopus 로고
    • Vascular remodeling of the mouse yolk sac requires hemodynamic force
    • Lucitti JL, Jones EAV, Huang C, et al. 2007. Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development 134: 3317-3326.
    • (2007) Development , vol.134 , pp. 3317-3326
    • Lucitti, J.L.1    Jones, E.A.V.2    Huang, C.3
  • 46
    • 0031969557 scopus 로고    scopus 로고
    • Oxygen, genes, and development:An analysis of the role of hypoxic gene regulation during murine vascular development
    • Maltepe E and Celeste Simon M. 1998. Oxygen, genes, and development:An analysis of the role of hypoxic gene regulation during murine vascular development. J Mol Med 76: 391-401.
    • (1998) J Mol Med , vol.76 , pp. 391-401
    • Maltepe, E.1    Celeste Simon, M.2
  • 47
    • 64049119418 scopus 로고    scopus 로고
    • Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef database
    • Martin MT, Judson RS, Reif DM, et al. 2009a. Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef database. Environ Health Perspect 117: 392-399.
    • (2009) Environ Health Perspect , vol.117 , pp. 392-399
    • Martin, M.T.1    Judson, R.S.2    Reif, D.M.3
  • 48
    • 80052549683 scopus 로고    scopus 로고
    • Predictive model of rat reproductive toxicity from ToxCast high-throughput screening
    • Martin MT, Knudsen TB, Reif DM, et al. 2011. Predictive model of rat reproductive toxicity from ToxCast high-throughput screening. Biol Reprod 85: 327-339.
    • (2011) Biol Reprod , vol.85 , pp. 327-339
    • Martin, M.T.1    Knudsen, T.B.2    Reif, D.M.3
  • 49
    • 67649233774 scopus 로고    scopus 로고
    • Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database
    • Martin MT, Mendez E, Corum DG, et al. 2009b. Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database. Toxicol Sci 110: 181-190.
    • (2009) Toxicol Sci , vol.110 , pp. 181-190
    • Martin, M.T.1    Mendez, E.2    Corum, D.G.3
  • 50
    • 2342596403 scopus 로고    scopus 로고
    • A Titin mutation defines roles for circulation in endothelial morphogenesis
    • May SR, Stewart NJ, Chang W and Peterson AS. 2004. A Titin mutation defines roles for circulation in endothelial morphogenesis. Dev Biol 270: 31-46.
    • (2004) Dev Biol , vol.270 , pp. 31-46
    • May, S.R.1    Stewart, N.J.2    Chang, W.3    Peterson, A.S.4
  • 51
    • 0035996082 scopus 로고    scopus 로고
    • Mainstream and sidestream cigarette smoke inhibit growth and angiogenesis in the day 5 chick chorioallantoic membrane
    • Melkonian G, Cheung L, Marr R, et al. 2002. Mainstream and sidestream cigarette smoke inhibit growth and angiogenesis in the day 5 chick chorioallantoic membrane. Toxicol Sci 68: 237-248.
    • (2002) Toxicol Sci , vol.68 , pp. 237-248
    • Melkonian, G.1    Cheung, L.2    Marr, R.3
  • 52
    • 0034718502 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and beta
    • Mueller MD, Vigne JL, Minchenko A, et al. 2000. Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and beta. Proc Natl Acad Sci U S A 97: 10972-10977.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10972-10977
    • Mueller, M.D.1    Vigne, J.L.2    Minchenko, A.3
  • 53
    • 0141618452 scopus 로고    scopus 로고
    • Growth and angiogenesis are inhibited in vivo in developing tissues by pyrazine and its derivatives
    • Melkonian G, Eckelhoefer H, Wu M, et al. 2003. Growth and angiogenesis are inhibited in vivo in developing tissues by pyrazine and its derivatives. Toxicol Sci 74: 393-401.
    • (2003) Toxicol Sci , vol.74 , pp. 393-401
    • Melkonian, G.1    Eckelhoefer, H.2    Wu, M.3
  • 55
    • 0037731526 scopus 로고    scopus 로고
    • Antiangiogenic Activity of N-substituted and tetrafluorinated thalidomide analogues
    • Ng SSW, Gütschow M, Weiss M, et al. 2003. Antiangiogenic Activity of N-substituted and tetrafluorinated thalidomide analogues. Cancer Res 63: 3189-3194.
    • (2003) Cancer Res , vol.63 , pp. 3189-3194
    • Ng, S.S.W.1    Gütschow, M.2    Weiss, M.3
  • 56
    • 27644582508 scopus 로고    scopus 로고
    • Angiogenesis inhibitors derived from thalidomide
    • Noguchi T, Fujimoto H, Sano H, et al. 2005. Angiogenesis inhibitors derived from thalidomide. Bioorg Med Chem Lett 15: 5509-5513.
    • (2005) Bioorg Med Chem Lett , vol.15 , pp. 5509-5513
    • Noguchi, T.1    Fujimoto, H.2    Sano, H.3
  • 57
    • 80052933197 scopus 로고
    • Basic and therapeutic aspects of angiogenesis
    • Potente M, Gerhardt H, Carmeliet P. Basic and therapeutic aspects of angiogenesis. Cell 0000 146: 873-887.
    • (0) Cell , vol.146 , pp. 873-887
    • Potente, M.1    Gerhardt, H.2    Carmeliet, P.3
  • 58
    • 21444452805 scopus 로고    scopus 로고
    • Vasculogenesis and angiogenesis in the mouse embryo studied using quail/mouse chimeras
    • Pudliszewski M and Pardanaud L. 2005. Vasculogenesis and angiogenesis in the mouse embryo studied using quail/mouse chimeras. Int J Dev Biol 49: 355-361.
    • (2005) Int J Dev Biol , vol.49 , pp. 355-361
    • Pudliszewski, M.1    Pardanaud, L.2
  • 59
    • 78650284457 scopus 로고    scopus 로고
    • Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data
    • Reif D, Martin M, Tan S, et al. (2010) Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data. Environ Hlth Persp 118: 1714-1720.
    • (2010) Environ Hlth Persp , vol.118 , pp. 1714-1720
    • Reif, D.1    Martin, M.2    Tan, S.3
  • 60
    • 0141730400 scopus 로고    scopus 로고
    • Screening for developmental toxicity of tobacco smoke constituents
    • Rogers JM and Abbott BD. 2003. Screening for developmental toxicity of tobacco smoke constituents. Toxicol Sci 75: 227-228.
    • (2003) Toxicol Sci , vol.75 , pp. 227-228
    • Rogers, J.M.1    Abbott, B.D.2
  • 61
    • 79959378371 scopus 로고    scopus 로고
    • Intra-laboratory pre-validation of a human cell based in vitro angiogenesis assay for testing angiogenesis modulators
    • Sarkanen J-R, Mannerström M, Vuorenpää H, et al. 2011. Intra-laboratory pre-validation of a human cell based in vitro angiogenesis assay for testing angiogenesis modulators. Front Pharmacol 1: 1-13.
    • (2011) Front Pharmacol , vol.1 , pp. 1-13
    • Sarkanen, J.-R.1    Mannerström, M.2    Vuorenpää, H.3
  • 62
    • 0033876198 scopus 로고    scopus 로고
    • Thalidomide inhibits angiogenesis in embryoid bodies by the generation of hydroxyl radicals
    • Sauer H, Günther J, Hescheler J, Wartenberg M. 2000. Thalidomide inhibits angiogenesis in embryoid bodies by the generation of hydroxyl radicals. Am J Pathol 156: 151-158.
    • (2000) Am J Pathol , vol.156 , pp. 151-158
    • Sauer, H.1    Günther, J.2    Hescheler, J.3    Wartenberg, M.4
  • 63
    • 33747621613 scopus 로고    scopus 로고
    • Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor
    • Semenza GL. 2006. Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor. Exp Physiol 91: 803-806.
    • (2006) Exp Physiol , vol.91 , pp. 803-806
    • Semenza, G.L.1
  • 64
    • 79951900953 scopus 로고    scopus 로고
    • Using nuclear receptor activity to stratify hepatocarcinogens
    • Shah I, Houck K, Judson RS, et al. 2011. Using nuclear receptor activity to stratify hepatocarcinogens. PLoS One 6: e14584.
    • (2011) PLoS One , vol.6
    • Shah, I.1    Houck, K.2    Judson, R.S.3
  • 65
    • 80053516123 scopus 로고    scopus 로고
    • Predictive models of prenatal developmental toxicity from ToxCast high throughput screening data
    • Sipes NS, Martin MT, Reif DM, et al. 2011. Predictive models of prenatal developmental toxicity from ToxCast high throughput screening data. Toxicol Sci 124: 109-127.
    • (2011) Toxicol Sci , vol.124 , pp. 109-127
    • Sipes, N.S.1    Martin, M.T.2    Reif, D.M.3
  • 66
    • 0033066150 scopus 로고    scopus 로고
    • Teratogenic effects of the endothelin receptor antagonist L-753,037 in the rat
    • Spence S, Anderson C, Cukierski M, Patrick D. 1999. Teratogenic effects of the endothelin receptor antagonist L-753, 037 in the rat. Reprod Toxicol 13: 15-29.
    • (1999) Reprod Toxicol , vol.13 , pp. 15-29
    • Spence, S.1    Anderson, C.2    Cukierski, M.3    Patrick, D.4
  • 67
    • 56749104928 scopus 로고    scopus 로고
    • Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature
    • Stenman JM, Rajagopal J, Carroll TJ, Ishibashi M, et al. 2008. Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science 322: 1247-1250.
    • (2008) Science , vol.322 , pp. 1247-1250
    • Stenman, J.M.1    Rajagopal, J.2    Carroll, T.J.3    Ishibashi, M.4
  • 69
    • 3042712893 scopus 로고    scopus 로고
    • Retinoic acid controls blood vessel formation by modulating endothelial and mural cell interaction via suppression of Tie2 signaling in vascular progenitor cells
    • Suzuki Y, Komi Y, Ashino H, et al. 2004. Retinoic acid controls blood vessel formation by modulating endothelial and mural cell interaction via suppression of Tie2 signaling in vascular progenitor cells. Blood 104: 166-169.
    • (2004) Blood , vol.104 , pp. 166-169
    • Suzuki, Y.1    Komi, Y.2    Ashino, H.3
  • 70
    • 66649093493 scopus 로고    scopus 로고
    • Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation
    • Therapontos C, Erskine L, Gardner ER, et al. 2009. Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation. Proc Natl Acad Sci U S A 109: 8573-8578.
    • (2009) Proc Natl Acad Sci U S A , vol.109 , pp. 8573-8578
    • Therapontos, C.1    Erskine, L.2    Gardner, E.R.3
  • 71
    • 0033028390 scopus 로고    scopus 로고
    • Developmental toxicity and toxicokinetics of two endothelin receptor antagonists in rats and rabbits
    • Treinen K, Louden C, Dennis M, and Wier P. 1999. Developmental toxicity and toxicokinetics of two endothelin receptor antagonists in rats and rabbits. Teratology 59: 51-59.
    • (1999) Teratology , vol.59 , pp. 51-59
    • Treinen, K.1    Louden, C.2    Dennis, M.3    Wier, P.4
  • 73
    • 73149091643 scopus 로고    scopus 로고
    • Thalidomide-induced limb defects:resolving a 50-year-old puzzle
    • Vargesson N. 2009. Thalidomide-induced limb defects:resolving a 50-year-old puzzle. BioEssays 31: 1327-1336.
    • (2009) BioEssays , vol.31 , pp. 1327-1336
    • Vargesson, N.1
  • 74
    • 51349110512 scopus 로고    scopus 로고
    • Three-dimensional analysis of vascular development in the mouse embryo
    • Walls JR, Coultas L, Rossant J, Henkelman RM. 2008. Three-dimensional analysis of vascular development in the mouse embryo. PLoS ONE 3: e2853.
    • (2008) PLoS ONE , vol.3
    • Walls, J.R.1    Coultas, L.2    Rossant, J.3    Henkelman, R.M.4
  • 75
    • 73249124004 scopus 로고    scopus 로고
    • Identification of small molecule compounds that inhibit the HIF-1 signaling pathway
    • Xia M, Bi K, Cho MH, et al. 2009. Identification of small molecule compounds that inhibit the HIF-1 signaling pathway. Mol Cancer 8: 117.
    • (2009) Mol Cancer , vol.8 , pp. 117
    • Xia, M.1    Bi, K.2    Cho, M.H.3
  • 76
    • 22044444554 scopus 로고    scopus 로고
    • Thalidomide-induced antiangiogenic action is mediated by ceramide through depletion of VEGF receptors, and is antagonized by sphingosine-1-phosphate
    • Yabu T, Okazaki T, Tomimoto H, et al. 2005. Thalidomide-induced antiangiogenic action is mediated by ceramide through depletion of VEGF receptors, and is antagonized by sphingosine-1-phosphate. Blood 106: 125-134.
    • (2005) Blood , vol.106 , pp. 125-134
    • Yabu, T.1    Okazaki, T.2    Tomimoto, H.3
  • 77
    • 33750491949 scopus 로고    scopus 로고
    • Effects of copper deficiency on mouse yolk sac vasculature and expression of angiogenic mediators
    • Yang SJ, Uriu-Adams JY, Keen CL, et al. 2006. Effects of copper deficiency on mouse yolk sac vasculature and expression of angiogenic mediators. Birth Defects Res B 77:445-454.
    • (2006) Birth Defects Res B , vol.77 , pp. 445-454
    • Yang, S.J.1    Uriu-Adams, J.Y.2    Keen, C.L.3


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