-
1
-
-
0037703184
-
Role of PIGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
-
Autiero, M., J. Waltenberger, D. Communi, A. Kranz, L. Moons, D. Lambrechts, J. Kroll, S. Plaisance, M. De Mol, F. Bono, S. Kliche, G. Fellbrich, K. Ballmer-Hofer, D. Maglione, U. Mayr-Beyrle, M. Dewerchin, S. Dombrowski, D. Stanimirovic, P. Van Hummelen, C. Dehio, D. J. Hicklin, G. Persico, J. M. Herbert, D. Communi, M. Shibuya, D. Collen, E. M. Conway, and P. Carmeliet. 2003. Role of PIGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat. Med. 7:936-943.
-
(2003)
Nat. Med.
, vol.7
, pp. 936-943
-
-
Autiero, M.1
Waltenberger, J.2
Communi, D.3
Kranz, A.4
Moons, L.5
Lambrechts, D.6
Kroll, J.7
Plaisance, S.8
De Mol, M.9
Bono, F.10
Kliche, S.11
Fellbrich, G.12
Ballmer-Hofer, K.13
Maglione, D.14
Mayr-Beyrle, U.15
Dewerchin, M.16
Dombrowski, S.17
Stanimirovic, D.18
Van Hummelen, P.19
Dehio, C.20
Hicklin, D.J.21
Persico, G.22
Herbert, J.M.23
Communi, D.24
Shibuya, M.25
Collen, D.26
Conway, E.M.27
Carmeliet, P.28
more..
-
2
-
-
0022485548
-
The neu oncogene encodes an epidermal growth factor receptor-related protein
-
Bargmann, C. I., M. C. Hung, and R. A. Weinberg. 1986. The neu oncogene encodes an epidermal growth factor receptor-related protein. Cell 45:649-657.
-
(1986)
Cell
, vol.45
, pp. 649-657
-
-
Bargmann, C.I.1
Hung, M.C.2
Weinberg, R.A.3
-
3
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet, P., V. Ferreira, G. Breier, S. Pollefeyt, L. Kieckens, M. Gertsenstein, M. Fahrig, A. Vandenhoeck, K. Harpal, C. Eberhardt, C. Declercq, J. Pawling, L. Moons, D. Collen, W. Risau, and A. Nagy. 1996. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435-439.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
Declercq, C.11
Pawling, J.12
Moons, L.13
Collen, D.14
Risau, W.15
Nagy, A.16
-
4
-
-
0037311959
-
Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse
-
Ema, M., P. Faloon, W. J. Zhang, M. Hirashima, T. Reid, W. L. Stanford, S. Orkin, K. Choi, and J. Rossant. 2003. Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse. Genes Dev. 17:380-393.
-
(2003)
Genes Dev.
, vol.17
, pp. 380-393
-
-
Ema, M.1
Faloon, P.2
Zhang, W.J.3
Hirashima, M.4
Reid, T.5
Stanford, W.L.6
Orkin, S.7
Choi, K.8
Rossant, J.9
-
5
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara, N., K. Carver-Moore, H. Chen, M. Dowd, L. Lu, K. S. O'Shea, L. Powell-Braxton, K. J. Hillan, and M. W. Moore. 1996. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380:439-442.
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
6
-
-
0031039243
-
The biology of vascular endothelial growth factor
-
Ferrara, N., and T. Davis-Smyth. 1997. The biology of vascular endothelial growth factor. Endocr. Rev. 18:4-25.
-
(1997)
Endocr. Rev.
, vol.18
, pp. 4-25
-
-
Ferrara, N.1
Davis-Smyth, T.2
-
7
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
Fong, G. H., J. Rossant, M. Gertsenstein, and M. L. Breitman. 1995. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376:66-70.
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
8
-
-
0033334764
-
Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity
-
He, Y., S. K. Smith, K. A. Day, D. E. Clark, D. R. Licence, and D. S. Charnock-Jones. 1999. Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol. Endocrinol. 13:537-545.
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 537-545
-
-
He, Y.1
Smith, S.K.2
Day, K.A.3
Clark, D.E.4
Licence, D.R.5
Charnock-Jones, D.S.6
-
9
-
-
0028838012
-
Dimerization of cell surface receptors in signal transduction
-
Heldin, C. H. 1995. Dimerization of cell surface receptors in signal transduction. Cell 80:213-223.
-
(1995)
Cell
, vol.80
, pp. 213-223
-
-
Heldin, C.H.1
-
10
-
-
0032482978
-
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
-
Hiratsuka, S., O. Minowa, J. Kuno, T. Noda, and M. Shibuya. 1998. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc. Natl. Acad. Sci. USA 95:9349-9354.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9349-9354
-
-
Hiratsuka, S.1
Minowa, O.2
Kuno, J.3
Noda, T.4
Shibuya, M.5
-
11
-
-
0036782035
-
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
-
Hiratsuka, S., K. Nakamura, S. Iwai, M. Murakami, T. Itoh, H. Kijima, J. M. Shipley, R. M. Senior, and M. Shibuya. 2002. MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell 2:289-300.
-
(2002)
Cancer Cell
, vol.2
, pp. 289-300
-
-
Hiratsuka, S.1
Nakamura, K.2
Iwai, S.3
Murakami, M.4
Itoh, T.5
Kijima, H.6
Shipley, J.M.7
Senior, R.M.8
Shibuya, M.9
-
12
-
-
0027421333
-
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
-
Kendall, R. L., and K. A. Thomas. 1993. Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc. Natl. Acad. Sci. USA 90:10705-10709.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10705-10709
-
-
Kendall, R.L.1
Thomas, K.A.2
-
13
-
-
0032570774
-
Genomic organization of the flt-1 gene encoding for vascular endothelial growth factor (VEGF) receptor-1 suggests an intimate evolutionary relationship between the 7-Ig and the 5-Ig tyrosine kinase receptors
-
Kondo, K., S. Hiratsuka, E. Subbalakshmi, H. Matsushime, and M. Shibuya. 1998. Genomic organization of the flt-1 gene encoding for vascular endothelial growth factor (VEGF) receptor-1 suggests an intimate evolutionary relationship between the 7-Ig and the 5-Ig tyrosine kinase receptors. Gene 208:297-305.
-
(1998)
Gene
, vol.208
, pp. 297-305
-
-
Kondo, K.1
Hiratsuka, S.2
Subbalakshmi, E.3
Matsushime, H.4
Shibuya, M.5
-
14
-
-
0005419856
-
Significant expression of vascular endothelial growth factor/vascular permeability factor in mouse ascites tumors
-
Luo, J. C., S. Yamaguchi, A. Shinkai, K. Shitara, and M. Shibuya. 1998. Significant expression of vascular endothelial growth factor/vascular permeability factor in mouse ascites tumors. Cancer Res. 58:2652-2660.
-
(1998)
Cancer Res.
, vol.58
, pp. 2652-2660
-
-
Luo, J.C.1
Yamaguchi, S.2
Shinkai, A.3
Shitara, K.4
Shibuya, M.5
-
15
-
-
0025998533
-
A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit
-
Matthews, W., C. T. Jordan, M. Gavin, N. A. Jenkins, N. G. Copeland, and I. R. Lemischka. 1991. A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc. Natl. Acad. Sci. USA 88:9026-9030.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9026-9030
-
-
Matthews, W.1
Jordan, C.T.2
Gavin, M.3
Jenkins, N.A.4
Copeland, N.G.5
Lemischka, I.R.6
-
16
-
-
0032913939
-
VEGF deprivation-induced apoptosis is a component of programmed capillary regression
-
Meeson, A. P., M. Argilla, K. Ko, L. Witte, and R. A. Lang. 1999. VEGF deprivation-induced apoptosis is a component of programmed capillary regression. Development 126:1407-1415.
-
(1999)
Development
, vol.126
, pp. 1407-1415
-
-
Meeson, A.P.1
Argilla, M.2
Ko, K.3
Witte, L.4
Lang, R.A.5
-
17
-
-
0029021904
-
Endothelial receptor tyrosine kinases involved in angiogenesis
-
Mustonen, T., and K. Alitalo. 1995. Endothelial receptor tyrosine kinases involved in angiogenesis. J. Cell Biol. 129:895-898.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 895-898
-
-
Mustonen, T.1
Alitalo, K.2
-
18
-
-
0031833476
-
Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages
-
Nishikawa, S. I., S. Nishikawa, M. Hiroshima, N. Matsuyoshi, and H. Kodama. 1998. Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development 125:1747-1757.
-
(1998)
Development
, vol.125
, pp. 1747-1757
-
-
Nishikawa, S.I.1
Nishikawa, S.2
Hiroshima, M.3
Matsuyoshi, N.4
Kodama, H.5
-
19
-
-
0028134936
-
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR
-
Park, J. E., H. H. Chen, J. Winer, K. A. Houck, and N. Ferrara. 1994. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J. Biol. Chem. 269:25646-25654.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25646-25654
-
-
Park, J.E.1
Chen, H.H.2
Winer, J.3
Houck, K.A.4
Ferrara, N.5
-
20
-
-
0030952289
-
Mechanisms of angiogenesis
-
Risau, W. 1997. Mechanisms of angiogenesis. Nature 386:671-674.
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
21
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
Shalaby, F., J. Rossant, T. P. Yamaguchi, M. Gertsenstein, X. F. Wu, M. L. Breitman, and A. C. Schuh. 1995. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376:62-66.
-
(1995)
Nature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.P.3
Gertsenstein, M.4
Wu, X.F.5
Breitman, M.L.6
Schuh, A.C.7
-
22
-
-
0035003384
-
Structure and function of VEGF/VEGF-receptor system involved in angiogenesis
-
Shibuya, M. 2001. Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct. Funct. 26:25-35.
-
(2001)
Cell Struct. Funct.
, vol.26
, pp. 25-35
-
-
Shibuya, M.1
-
23
-
-
0025259592
-
Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (fit) closely related to the fms family
-
Shibuya, M., S. Yamaguchi, A. Yamane, T. Ikeda, A. Tojo, H. Matsushime, and M. Sato. 1990. Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (fit) closely related to the fms family. Oncogene 5:519-524.
-
(1990)
Oncogene
, vol.5
, pp. 519-524
-
-
Shibuya, M.1
Yamaguchi, S.2
Yamane, A.3
Ikeda, T.4
Tojo, A.5
Matsushime, H.6
Sato, M.7
-
24
-
-
0035355472
-
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells
-
Takahashi, T., S. Yamaguchi, K. Chida, and M. Shibuya. 2001. A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells. EMBO J. 20:2768-2778.
-
(2001)
EMBO J.
, vol.20
, pp. 2768-2778
-
-
Takahashi, T.1
Yamaguchi, S.2
Chida, K.3
Shibuya, M.4
-
25
-
-
0034697966
-
A role for hematopoietic stem cells in promoting angiogenesis
-
Takakura, N., T. Watanabe, S. Suenobu, Y. Yamada, T. Noda, Y. Ito, M. Satake, and T. Suda. 2000. A role for hematopoietic stem cells in promoting angiogenesis. Cell 102:199-209.
-
(2000)
Cell
, vol.102
, pp. 199-209
-
-
Takakura, N.1
Watanabe, T.2
Suenobu, S.3
Yamada, Y.4
Noda, T.5
Ito, Y.6
Satake, M.7
Suda, T.8
-
26
-
-
0026702970
-
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
-
Terman, B. I., M. Dougher-Vermazen, M. E. Carrion, D. Dimitrov, D. C. Armellino, D. Gospodarowicz, and P. Bohlen. 1992. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem. Biophys. Res. Commun. 187:1579-1586.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.187
, pp. 1579-1586
-
-
Terman, B.I.1
Dougher-Vermazen, M.2
Carrion, M.E.3
Dimitrov, D.4
Armellino, D.C.5
Gospodarowicz, D.6
Bohlen, P.7
-
27
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ulrich, A., and J. Schlessinger. 1990. Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ulrich, A.1
Schlessinger, J.2
-
28
-
-
0034789517
-
Receptor tyrosine kinase signalling as a target for cancer intervention strategies
-
Zwick, E., J. Bange, and A. Ullrich. 2001. Receptor tyrosine kinase signalling as a target for cancer intervention strategies. Endocr. Relat. Cancer 8:161-173.
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 161-173
-
-
Zwick, E.1
Bange, J.2
Ullrich, A.3
|