Predictive model of rat reproductive toxicity from ToxCast high throughput screening

Biology of Reproduction

Volumn 85, Issue 2, 2011, Pages 327-339

  Martin, Matthew T ^a   Knudsen, Thomas B ^a   Reif, David M ^a   Houck, Keith A ^a   Judson, Richard S ^a   Kavlock, Robert J ^a   Dix, David J ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Female reproductive tract; Fertility; Male reproductive tract; Predictive toxicology; Reproductive toxicity; Toxicology

Indexed keywords

ABAMECTIN; ALACHLOR; BROMOXYNIL; CELL NUCLEUS RECEPTOR; CHLORSULFURON; CYTOCHROME P450; DAMINOZIDE; DICAMBA; DICHLORPROP; DICHLORVOS; DICOFOL; DICROTOPHOS; DIMETHOATE; DIMPYLATE; DIPHENYLAMINE; DISULFOTON; ENVIRONMENTAL CHEMICAL; FENARIMOL; FENITROTHION; FENVALERATE; G PROTEIN COUPLED RECEPTOR; METHOXYCHLOR; MILBEMECTIN; PHTHALIC ACID DIBUTYL ESTER; PROCHLORAZ; SPIROXAMINE; TEBUPIRIMFOS; TEFLUTHRIN; TRIBUFOS; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; DISCRIMINANT ANALYSIS; ENZYME INHIBITION; FEMALE; FEMALE GENITAL SYSTEM; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; IN VIVO STUDY; MALE; MALE GENITAL SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCTIVE TOXICITY; SIGNAL TRANSDUCTION; VALIDATION PROCESS;

ANIMALS; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION REGULATION; MALE; PREDICTIVE VALUE OF TESTS; RATS; REPRODUCTION; RISK ASSESSMENT; SMALL MOLECULE LIBRARIES; TOXICITY TESTS; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

RATTUS; RODENTIA;

EID: 80052549683     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.111.090977     Document Type: Article

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