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Volumn 37, Issue 1, 2012, Pages 247-260

Epigenetic treatments for cognitive impairments

Author keywords

development; drug discovery; epigenetics; learning and memory; neurodegeneration; neuroprotection

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BUTYRIC ACID; CLOZAPINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE INHIBITOR; FRAGILE X MENTAL RETARDATION PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HISTONE DEMETHYLASE; HUNTINGTIN; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE 1; N PHTHALOYLTRYPTOPHAN; NUCLEAR RECEPTOR RELATED FACTOR 1; PRION PROTEIN; REELIN; RESVERATROL; SIRTUIN 1; SULPIRIDE; TRICHOSTATIN A; VALPROIC ACID; VORINOSTAT; ZEBULARINE;

EID: 84856111959     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.85     Document Type: Review
Times cited : (82)

References (152)
  • 1
    • 38649124003 scopus 로고    scopus 로고
    • Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders
    • Abel T, Zukin RS (2008). Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders. Curr Opin Pharmacol 8: 57-64.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 57-64
    • Abel, T.1    Zukin, R.S.2
  • 2
    • 65249109439 scopus 로고    scopus 로고
    • MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome
    • Adachi M, Autry AE, Covington III HE, Monteggia LM (2009). MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome. J Neurosci 29: 4218-4227.
    • (2009) J Neurosci , vol.29 , pp. 4218-4227
    • Adachi, M.1    Autry, A.E.2    Covington Iii, H.E.3    Monteggia, L.M.4
  • 3
    • 38849159213 scopus 로고    scopus 로고
    • A novel mutation in JARID1C/SMCX in a patient with autism spectrum disorder (ASD)
    • DOI 10.1002/ajmg.a.32142
    • Adegbola A, Gao H, Sommer S, Browning M (2008). A novel mutation in JARID1C/SMCX in a patient with autism spectrum disorder (ASD). Am J Med Genet A 146A: 505-511. (Pubitemid 351206826)
    • (2008) American Journal of Medical Genetics, Part A , vol.146 , Issue.4 , pp. 505-511
    • Adegbola, A.1    Gao, H.2    Sommer, S.3    Browning, M.4
  • 4
    • 58149316420 scopus 로고    scopus 로고
    • Epigenetic regulation in human brain-focus on histone lysine methylation
    • Akbarian S, Huang HS (2009). Epigenetic regulation in human brain-focus on histone lysine methylation. Biol Psychiatry 65: 198-203.
    • (2009) Biol Psychiatry , vol.65 , pp. 198-203
    • Akbarian, S.1    Huang, H.S.2
  • 5
    • 2942705826 scopus 로고    scopus 로고
    • +/- mice: A model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration
    • DOI 10.1016/j.neuron.2004.05.021, PII S0896627304003022
    • Alarcon JM, Malleret G, Touzani K, Vronskaya S, Ishii S, Kandel ER et al. (2004). Chromatin acetylation, memory, and LTP are impaired in CBP%+/mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron 42: 947-959. (Pubitemid 38798233)
    • (2004) Neuron , vol.42 , Issue.6 , pp. 947-959
    • Alarcon, J.M.1    Malleret, G.2    Touzani, K.3    Vronskaya, S.4    Ishii, S.5    Kandel, E.R.6    Barco, A.7
  • 6
    • 39849094746 scopus 로고    scopus 로고
    • The role of protein synthesis during the labile phases of memory: Revisiting the skepticism
    • DOI 10.1016/j.nlm.2007.08.007, PII S1074742707001244
    • Alberini CM (2008). The role of protein synthesis during the labile phases of memory: revisiting the skepticism. Neurobiol Learn Mem 89: 234-246. (Pubitemid 351318267)
    • (2008) Neurobiology of Learning and Memory , vol.89 , Issue.3 , pp. 234-246
    • Alberini, C.M.1
  • 7
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl- CpG-binding protein 2
    • DOI 10.1038/13810
    • Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY (1999). Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpGbinding protein 2. Nat Genet 23: 185-188. (Pubitemid 29455390)
    • (1999) Nature Genetics , vol.23 , Issue.2 , pp. 185-188
    • Amir, R.E.1    Van Den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 8
    • 0033646967 scopus 로고    scopus 로고
    • Rett syndrome: Methyl-CpG-binding protein 2 mutations and phenotype-genotype correlations
    • Amir RE, Zoghbi HY (2000). Rett syndrome: methyl-CpG-binding protein 2 mutations and phenotype-genotype correlations. Am J Med Genet 97: 147-152.
    • (2000) Am J Med Genet , vol.97 , pp. 147-152
    • Amir, R.E.1    Zoghbi, H.Y.2
  • 9
    • 29144440149 scopus 로고    scopus 로고
    • Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome
    • DOI 10.1016/j.nbd.2005.07.005, PII S0969996105002044
    • Asaka Y, Jugloff DG, Zhang L, Eubanks JH, Fitzsimonds RM (2006). Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome. Neurobiol Dis 21: 217-227. (Pubitemid 41817320)
    • (2006) Neurobiology of Disease , vol.21 , Issue.1 , pp. 217-227
    • Asaka, Y.1    Jugloff, D.G.M.2    Zhang, L.3    Eubanks, J.H.4    Fitzsimonds, R.M.5
  • 10
    • 79959847254 scopus 로고    scopus 로고
    • The role of deubiquitinating enzymes in chromatin regulation
    • doi:10.1016/j.febslet.2010.10.042
    • Atanassov BS, Koutelou E, Dent SY (2010). The role of deubiquitinating enzymes in chromatin regulation. FEBS Lett. doi:10.1016/j.febslet.2010.10.042.
    • (2010) FEBS Lett.
    • Atanassov, B.S.1    Koutelou, E.2    Dent, S.Y.3
  • 11
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 12
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • DOI 10.1038/nature05915, PII NATURE05915
    • Berger SL (2007). The complex language of chromatin regulation during transcription. Nature 447: 407-412. (Pubitemid 46816746)
    • (2007) Nature , vol.447 , Issue.7143 , pp. 407-412
    • Berger, S.L.1
  • 13
    • 32044432375 scopus 로고    scopus 로고
    • Reduced extinction of hippocampal-dependent memories in CPEB knockout mice
    • DOI 10.1101/lm.73706
    • Berger-Sweeney J, Zearfoss NR, Richter JD (2006). Reduced extinction of hippocampal-dependent memories in CPEB knockout mice. Learn Mem 13: 4-7. (Pubitemid 43200812)
    • (2006) Learning and Memory , vol.13 , Issue.1 , pp. 4-7
    • Berger-Sweeney, J.1    Zearfoss, N.R.2    Richter, J.D.3
  • 14
    • 45949098156 scopus 로고    scopus 로고
    • Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol
    • Bertran-Gonzalez J, Bosch C, Maroteaux M, Matamales M, Herve D, Valjent E et al. (2008). Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol. J Neurosci 28: 5671-5685.
    • (2008) J Neurosci , vol.28 , pp. 5671-5685
    • Bertran-Gonzalez, J.1    Bosch, C.2    Maroteaux, M.3    Matamales, M.4    Herve, D.5    Valjent, E.6
  • 15
    • 67349263366 scopus 로고    scopus 로고
    • Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons
    • Bertran-Gonzalez J, Hakansson K, Borgkvist A, Irinopoulou T, Brami-Cherrier K, Usiello A et al. (2009). Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons. Neuropsychopharmacology 34: 1710-1720.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1710-1720
    • Bertran-Gonzalez, J.1    Hakansson, K.2    Borgkvist, A.3    Irinopoulou, T.4    Brami-Cherrier, K.5    Usiello, A.6
  • 16
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • DOI 10.1038/nature05913, PII NATURE05913
    • Bird A (2007). Perceptions of epigenetics. Nature 447: 396-398. (Pubitemid 46816744)
    • (2007) Nature , vol.447 , Issue.7143 , pp. 396-398
    • Bird, A.1
  • 17
    • 79951686964 scopus 로고    scopus 로고
    • The sirtuin pathway in ageing and Alzheimer disease: Mechanistic and therapeutic considerations
    • Bonda DJ, Lee HG, Camins A, Pallas M, Casadesus G, Smith MA et al. (2011). The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations. Lancet Neurol 10: 275-279.
    • (2011) Lancet Neurol , vol.10 , pp. 275-279
    • Bonda, D.J.1    Lee, H.G.2    Camins, A.3    Pallas, M.4    Casadesus, G.5    Smith, M.A.6
  • 19
    • 77951483682 scopus 로고    scopus 로고
    • How the epigenome contributes to the development of psychiatric disorders
    • Bredy TW, Sun YE, Kobor MS (2010). How the epigenome contributes to the development of psychiatric disorders. Dev Psychobiol 52: 331-342.
    • (2010) Dev Psychobiol , vol.52 , pp. 331-342
    • Bredy, T.W.1    Sun, Y.E.2    Kobor, M.S.3
  • 20
    • 37249071337 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer treatment: A review of the clinical toxicity and the modulation of gene expression in cancer cells
    • DOI 10.2174/138920107783018417
    • Bruserud O, Stapnes C, Ersvaer E, Gjertsen BT, Ryningen A (2007). Histone deacetylase inhibitors in cancer treatment: a review of the clinical toxicity and the modulation of gene expression in cancer cell. Curr Pharm Biotechnol 8: 388-400. (Pubitemid 350268198)
    • (2007) Current Pharmaceutical Biotechnology , vol.8 , Issue.6 , pp. 388-400
    • Bruserud, O.1    Stapnes, C.2    Ersvaer, E.3    Gjertsen, B.T.4    Ryningen, A.5
  • 21
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • DOI 10.1126/science.1153252
    • Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J et al. (2008). MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320: 1224-1229. (Pubitemid 351929512)
    • (2008) Science , vol.320 , Issue.5880 , pp. 1224-1229
    • Chahrour, M.1    Sung, Y.J.2    Shaw, C.3    Zhou, X.4    Wong, S.T.C.5    Qin, J.6    Zoghbi, H.Y.7
  • 22
    • 0034644473 scopus 로고    scopus 로고
    • Signaling to chromatin through histone modifications
    • Cheung P, Allis CD, Sassone-Corsi P (2000). Signaling to chromatin through histone modifications. Cell 103: 263-271.
    • (2000) Cell , vol.103 , pp. 263-271
    • Cheung, P.1    Allis, C.D.2    Sassone-Corsi, P.3
  • 23
  • 24
    • 36249006058 scopus 로고    scopus 로고
    • The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation
    • DOI 10.1523/JNEUROSCI.2522-07.2007
    • Chwang WB, Arthur JS, Schumacher A, Sweatt JD (2007). The nuclear kinase mitogen-and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation. J Neurosci 27: 12732-12742. (Pubitemid 350127810)
    • (2007) Journal of Neuroscience , vol.27 , Issue.46 , pp. 12732-12742
    • Chwang, W.B.1    Arthur, J.S.2    Schumacher, A.3    Sweatt, J.D.4
  • 25
    • 33744793463 scopus 로고    scopus 로고
    • ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning
    • DOI 10.1101/lm.152906
    • Chwang WB, O'Riordan KJ, Levenson JM, Sweatt JD (2006). ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning. Learn Mem 13: 322-328. (Pubitemid 43830678)
    • (2006) Learning and Memory , vol.13 , Issue.3 , pp. 322-328
    • Chwang, W.B.1    O'Riordan, K.J.2    Levenson, J.M.3    Sweatt, J.D.4
  • 26
    • 33746457753 scopus 로고    scopus 로고
    • Enhanced Histone Acetylation and Transcription: A Dynamic Perspective
    • DOI 10.1016/j.molcel.2006.06.017, PII S1097276506004321
    • Clayton AL, Hazzalin CA, Mahadevan LC (2006). Enhanced histone acetylation and transcription: a dynamic perspective. Mol Cell 23: 289-296. (Pubitemid 44128853)
    • (2006) Molecular Cell , vol.23 , Issue.3 , pp. 289-296
    • Clayton, A.L.1    Hazzalin, C.A.2    Mahadevan, L.C.3
  • 30
    • 36849154193 scopus 로고
    • Memory and molecular turnover
    • Crick F (1984). Memory and molecular turnover. Nature 312: 101.
    • (1984) Nature , vol.312 , pp. 101
    • Crick, F.1
  • 31
    • 77958580776 scopus 로고    scopus 로고
    • DNA methylation and memory formation
    • Day JJ, Sweatt JD (2010). DNA methylation and memory formation. Nat Neurosci 13: 1319-1323.
    • (2010) Nat Neurosci , vol.13 , pp. 1319-1323
    • Day, J.J.1    Sweatt, J.D.2
  • 33
  • 34
    • 78449250771 scopus 로고    scopus 로고
    • Valproate induces DNA demethylation in nuclear extracts from adult mouse brain
    • Dong E, Chen Y, Gavin DP, Grayson DR, Guidotti A (2010). Valproate induces DNA demethylation in nuclear extracts from adult mouse brain. Epigenetics 5: 730-735.
    • (2010) Epigenetics , vol.5 , pp. 730-735
    • Dong, E.1    Chen, Y.2    Gavin, D.P.3    Grayson, D.R.4    Guidotti, A.5
  • 35
    • 51649127761 scopus 로고    scopus 로고
    • Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation
    • Dong E, Nelson M, Grayson DR, Costa E, Guidotti A (2008). Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci USA 105: 13614-13619.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13614-13619
    • Dong, E.1    Nelson, M.2    Grayson, D.R.3    Costa, E.4    Guidotti, A.5
  • 36
    • 0026700732 scopus 로고
    • A DNA methylation imprint, determined by the sex of the parent, distinguishes the Angelman and Prader-Willi syndromes
    • Driscoll DJ, Waters MF, Williams CA, Zori RT, Glenn CC, Avidano KM et al. (1992). A DNA methylation imprint, determined by the sex of the parent, distinguishes the Angelman and Prader-Willi syndromes. Genomics 13: 917-924.
    • (1992) Genomics , vol.13 , pp. 917-924
    • Driscoll, D.J.1    Waters, M.F.2    Williams, C.A.3    Zori, R.T.4    Glenn, C.C.5    Avidano, K.M.6
  • 38
    • 77953429462 scopus 로고    scopus 로고
    • Brain function and chromatin plasticity
    • Dulac C (2010). Brain function and chromatin plasticity. Nature 465: 728-735.
    • (2010) Nature , vol.465 , pp. 728-735
    • Dulac, C.1
  • 39
    • 0035433364 scopus 로고    scopus 로고
    • Acetyllysine-binding and function of bromodomain-containing proteins in chromatin
    • Dyson MH, Rose S, Mahadevan LC (2001). Acetyllysine-binding and function of bromodomain-containing proteins in chromatin. Front Biosci 6: D853-D865.
    • (2001) Front Biosci , vol.6
    • Dyson, M.H.1    Rose, S.2    Mahadevan, L.C.3
  • 40
    • 75949101467 scopus 로고    scopus 로고
    • Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132
    • Edbauer D, Neilson JR, Foster KA, Wang CF, Seeburg DP, Batterton MN et al. (2010). Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron 65: 373-384.
    • (2010) Neuron , vol.65 , pp. 373-384
    • Edbauer, D.1    Neilson, J.R.2    Foster, K.A.3    Wang, C.F.4    Seeburg, D.P.5    Batterton, M.N.6
  • 41
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD et al. (2010). Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 13: 423-430.
    • (2010) Nat Neurosci , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le Li T, E.4    Sweatt, J.D.5
  • 42
    • 34248523169 scopus 로고    scopus 로고
    • Recovery of learning and memory is associated with chromatin remodelling
    • Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH
    • Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH (2007). Recovery of learning and memory is associated with chromatin remodelling. Nature 447: 178-182.
    • (2007) Nature , vol.447 , pp. 178-182
  • 45
    • 0030064318 scopus 로고    scopus 로고
    • Influence of actinomycin D, a RNA synthesis inhibitor, on long-term potentiation in rat hippocampal neurons in vivo and in vitro
    • Frey U, Frey S, Schollmeier F, Krug M (1996). Influence of actinomycin D, a RNA synthesis inhibitor, on long-term potentiation in rat hippocampal neurons in vivo and in vitro. J Physiol 490(Pt 3): 703-711. (Pubitemid 26058841)
    • (1996) Journal of Physiology , vol.490 , Issue.3 , pp. 703-711
    • Frey, U.1    Frey, S.2    Schollmeier, F.3    Krug, M.4
  • 46
    • 0023908218 scopus 로고
    • Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro
    • Frey U, Krug M, Reymann KG, Matthies H (1988). Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro. Brain Res 452: 57-65.
    • (1988) Brain Res , vol.452 , pp. 57-65
    • Frey, U.1    Krug, M.2    Reymann, K.G.3    Matthies, H.4
  • 47
    • 77956185062 scopus 로고    scopus 로고
    • A novel pathway regulates memory and plasticity via SIRT1 and miR-134
    • Gao J, Wang WY, Mao YW, Graff J, Guan JS, Pan L et al. (2010). A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 466: 1105-1109.
    • (2010) Nature , vol.466 , pp. 1105-1109
    • Gao, J.1    Wang, W.Y.2    Mao, Y.W.3    Graff, J.4    Guan, J.S.5    Pan, L.6
  • 48
    • 0028267714 scopus 로고
    • Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice
    • Goto K, Numata M, Komura JI, Ono T, Bestor TH, Kondo H (1994). Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 56: 39-44. (Pubitemid 24102005)
    • (1994) Differentiation , vol.56 , Issue.1-2 , pp. 39-44
    • Goto, K.1    Numata, M.2    Komura, J.-I.3    Ono, T.4    Bestor, T.H.5    Kondo, H.6
  • 49
    • 67649867069 scopus 로고    scopus 로고
    • Epigenetic dysregulation in cognitive disorders
    • Graff J, Mansuy IM (2009). Epigenetic dysregulation in cognitive disorders. Eur J Neurosci 30: 1-8.
    • (2009) Eur J Neurosci , vol.30 , pp. 1-8
    • Graff, J.1    Mansuy, I.M.2
  • 51
    • 77955285002 scopus 로고    scopus 로고
    • Sex-specific parent-of-origin allelic expression in the mouse brain
    • Gregg C, Zhang J, Butler JE, Haig D, Dulac C (2010a). Sex-specific parent-of-origin allelic expression in the mouse brain. Science 329: 682-685.
    • (2010) Science , vol.329 , pp. 682-685
    • Gregg, C.1    Zhang, J.2    Butler, J.E.3    Haig, D.4    Dulac, C.5
  • 52
    • 77955299096 scopus 로고    scopus 로고
    • High-resolution analysis of parent-of-origin allelic expression in the mouse brain
    • Gregg C, Zhang J, Weissbourd B, Luo S, Schroth GP, Haig D et al. (2010b). High-resolution analysis of parent-of-origin allelic expression in the mouse brain. Science 329: 643-648.
    • (2010) Science , vol.329 , pp. 643-648
    • Gregg, C.1    Zhang, J.2    Weissbourd, B.3    Luo, S.4    Schroth, G.P.5    Haig, D.6
  • 53
    • 30644474460 scopus 로고    scopus 로고
    • Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9
    • Greiner D, Bonaldi T, Eskeland R, Roemer E, Imhof A (2005). Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat Chem Biol 1: 143-145.
    • (2005) Nat Chem Biol , vol.1 , pp. 143-145
    • Greiner, D.1    Bonaldi, T.2    Eskeland, R.3    Roemer, E.4    Imhof, A.5
  • 56
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • DOI 10.1038/nrg1379
    • He L, Hannon GJ (2004). MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5: 522-531. (Pubitemid 38868508)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 57
    • 18944403738 scopus 로고    scopus 로고
    • Differential localization of MAPK-activated protein kinases RSK1 and MSK1 in mouse brain
    • DOI 10.1016/j.molbrainres.2005.01.014, PII S0169328X05000380
    • Heffron D, Mandell JW (2005). Differential localization of MAPK-activated protein kinases RSK1 and MSK1 in mouse brain. Brain Res Mol Brain Res 136: 134-141. (Pubitemid 40704616)
    • (2005) Molecular Brain Research , vol.136 , Issue.1-2 , pp. 134-141
    • Heffron, D.1    Mandell, J.W.2
  • 58
    • 68049119933 scopus 로고    scopus 로고
    • Poly-(ADP-ribose) polymerase-1 is necessary for long-term facilitation in Aplysia
    • Hernandez AI, Wolk J, Hu JY, Liu J, Kurosu T, Schwartz JH et al. (2009). Poly-(ADP-ribose) polymerase-1 is necessary for long-term facilitation in Aplysia. J Neurosci 29: 9553-9562.
    • (2009) J Neurosci , vol.29 , pp. 9553-9562
    • Hernandez, A.I.1    Wolk, J.2    Hu, J.Y.3    Liu, J.4    Kurosu, T.5    Schwartz, J.H.6
  • 59
    • 77956885503 scopus 로고    scopus 로고
    • Core histone H2A ubiquitylation and transcriptional regulation
    • Higashi M, Inoue S, Ito T (2010). Core histone H2A ubiquitylation and transcriptional regulation. Exp Cell Res 316: 2707-2712.
    • (2010) Exp Cell Res , vol.316 , pp. 2707-2712
    • Higashi, M.1    Inoue, S.2    Ito, T.3
  • 60
    • 39549090166 scopus 로고    scopus 로고
    • MeCP2 Binding to DNA Depends upon Hydration at Methyl-CpG
    • DOI 10.1016/j.molcel.2007.12.028, PII S1097276508000968
    • Ho KL, McNae IW, Schmiedeberg L, Klose RJ, Bird AP, Walkinshaw MD (2008). MeCP2 binding to DNA depends upon hydration at methyl-CpG. Mol Cell 29: 525-531. (Pubitemid 351282541)
    • (2008) Molecular Cell , vol.29 , Issue.4 , pp. 525-531
    • Ho, K.L.1    McNae, I.W.2    Schmiedeberg, L.3    Klose, R.J.4    Bird, A.P.5    Walkinshaw, M.D.6
  • 61
    • 77954510708 scopus 로고    scopus 로고
    • Striatal microRNA controls cocaine intake through CREB signalling
    • Hollander JA, Im HI, Amelio AL, Kocerha J, Bali P, Lu Q et al. (2010). Striatal microRNA controls cocaine intake through CREB signalling. Nature 466: 197-202.
    • (2010) Nature , vol.466 , pp. 197-202
    • Hollander, J.A.1    Im, H.I.2    Amelio, A.L.3    Kocerha, J.4    Bali, P.5    Lu, Q.6
  • 64
    • 0036008551 scopus 로고    scopus 로고
    • Histone ubiquitination: A tagging tail unfolds?
    • DOI 10.1002/bies.10038
    • Jason LJ, Moore SC, Lewis JD, Lindsey G, Ausio J (2002). Histone ubiquitination: a tagging tail unfolds? Bioessays 24: 166-174. (Pubitemid 34179295)
    • (2002) BioEssays , vol.24 , Issue.2 , pp. 166-174
    • Jason, L.J.M.1    Moore, S.C.2    Lewis, J.D.3    Lindsey, G.4    Ausi, J.5
  • 67
    • 36448958766 scopus 로고    scopus 로고
    • Function of the Drosophila CPEB protein Orb2 in long-term courtship memory
    • DOI 10.1038/nn1996, PII NN1996
    • Keleman K, Kruttner S, Alenius M, Dickson BJ (2007). Function of the Drosophila CPEB protein Orb2 in long-term courtship memory. Nat Neurosci 10: 1587-1593. (Pubitemid 350175870)
    • (2007) Nature Neuroscience , vol.10 , Issue.12 , pp. 1587-1593
    • Keleman, K.1    Kruttner, S.2    Alenius, M.3    Dickson, B.J.4
  • 68
    • 76749091005 scopus 로고    scopus 로고
    • Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease
    • Kilgore M, Miller CA, Fass DM, Hennig KM, Haggarty SJ, Sweatt JD et al. (2010). Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology 35: 870-880.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 870-880
    • Kilgore, M.1    Miller, C.A.2    Fass, D.M.3    Hennig, K.M.4    Haggarty, S.J.5    Sweatt, J.D.6
  • 70
    • 43049168861 scopus 로고    scopus 로고
    • Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation
    • Kim MO, Chawla P, Overland RP, Xia E, Sadri-Vakili G, Cha JH (2008). Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation. J Neurosci 28: 3947-3957.
    • (2008) J Neurosci , vol.28 , pp. 3947-3957
    • Kim, M.O.1    Chawla, P.2    Overland, R.P.3    Xia, E.4    Sadri-Vakili, G.5    Cha, J.H.6
  • 71
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: The mark and its mediators
    • DOI 10.1016/j.tibs.2005.12.008, PII S096800040500352X
    • Klose RJ, Bird AP (2006). Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 31: 89-97. (Pubitemid 43221841)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.2 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 73
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin Modifications and Their Function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • Kouzarides T (2007). Chromatin modifications and their function. Cell 128: 693-705. (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 75
    • 36849046285 scopus 로고    scopus 로고
    • Histone Crosstalk between H2B Monoubiquitination and H3 Methylation Mediated by COMPASS
    • DOI 10.1016/j.cell.2007.09.046, PII S0092867407013505
    • Lee JS, Shukla A, Schneider J, Swanson SK, Washburn MP, Florens L et al. (2007). Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell 131: 1084-1096. (Pubitemid 350235018)
    • (2007) Cell , vol.131 , Issue.6 , pp. 1084-1096
    • Lee, J.-S.1    Shukla, A.2    Schneider, J.3    Swanson, S.K.4    Washburn, M.P.5    Florens, L.6    Bhaumik, S.R.7    Shilatifard, A.8
  • 77
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • DOI 10.1038/366362a0
    • Li E, Beard C, Jaenisch R (1993). Role for DNA methylation in genomic imprinting. Nature 366: 362-365. (Pubitemid 23349366)
    • (1993) Nature , vol.366 , Issue.6453 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 79
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory
    • Lubin FD, Roth TL, Sweatt JD (2008). Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci 28: 10576-10586.
    • (2008) J Neurosci , vol.28 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 80
    • 66849119061 scopus 로고    scopus 로고
    • DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation
    • Ma DK, Guo JU, Ming GL, Song H (2009a). DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation. Cell Cycle 8: 1526-1531.
    • (2009) Cell Cycle , vol.8 , pp. 1526-1531
    • Ma, D.K.1    Guo, J.U.2    Ming, G.L.3    Song, H.4
  • 81
    • 60749094831 scopus 로고    scopus 로고
    • Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
    • Ma DK, Jang MH, Guo JU, Kitabatake Y, Chang ML, Pow-Anpongkul N et al. (2009b). Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 323: 1074-1077.
    • (2009) Science , vol.323 , pp. 1074-1077
    • Ma, D.K.1    Jang, M.H.2    Guo, J.U.3    Kitabatake, Y.4    Chang, M.L.5    Pow-Anpongkul, N.6
  • 82
    • 71349087123 scopus 로고    scopus 로고
    • Modulation of chromatin modification facilitates extinction of cocaine-induced conditioned place preference
    • Malvaez M, Sanchis-Segura C, Vo D, Lattal KM, Wood MA (2010). Modulation of chromatin modification facilitates extinction of cocaine-induced conditioned place preference. Biol Psychiatry 67: 36-43
    • (2010) Biol Psychiatry , vol.67 , pp. 36-43
    • Malvaez, M.1    Sanchis-Segura, C.2    Vo, D.3    Lattal, K.M.4    Wood, M.A.5
  • 83
    • 74249105659 scopus 로고    scopus 로고
    • Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
    • Maze I, Covington III HE, Dietz DM, LaPlant Q, Renthal W, Russo SJ et al. (2010). Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science 327: 213-216.
    • (2010) Science , vol.327 , pp. 213-216
    • Maze, I.1    Covington Iii, H.E.2    Dietz, D.M.3    Laplant, Q.4    Renthal, W.5    Russo, S.J.6
  • 84
    • 0142091423 scopus 로고    scopus 로고
    • Quantitative Analysis of CBP- and P300-Induced Histone Acetylations In Vivo Using Native Chromatin
    • DOI 10.1128/MCB.23.21.7611-7627.2003
    • McManus KJ, Hendzel MJ (2003). Quantitative analysis of CBP-and P300-induced histone acetylations in vivo using native chromatin. Mol Cell Biol 23: 7611-7627. (Pubitemid 37271460)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.21 , pp. 7611-7627
    • McManus, K.J.1    Hendzel, M.J.2
  • 86
    • 0034813107 scopus 로고    scopus 로고
    • Mitogen-regulated RSK2-CBP interaction controls their kinase and acetylase activities
    • DOI 10.1128/MCB.21.20.7089-7096.2001
    • Merienne K, Pannetier S, Harel-Bellan A, Sassone-Corsi P (2001). Mitogenregulated RSK2-CBP interaction controls their kinase and acetylase activities. Mol Cell Biol 21: 7089-7096. (Pubitemid 32911267)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.20 , pp. 7089-7096
    • Merienne, K.1    Pannetier, S.2    Harel-Bellan, A.3    Sassone-Corsi, P.4
  • 89
    • 41649096261 scopus 로고    scopus 로고
    • DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity
    • DOI 10.1016/j.nlm.2007.07.016, PII S1074742707001104
    • Miller CA, Campbell SL, Sweatt JD (2008). DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity. Neurobiol Learn Mem 89: 599-603. (Pubitemid 351484241)
    • (2008) Neurobiology of Learning and Memory , vol.89 , Issue.4 , pp. 599-603
    • Miller, C.A.1    Campbell, S.L.2    Sweatt, J.D.3
  • 91
    • 33847614418 scopus 로고    scopus 로고
    • Covalent Modification of DNA Regulates Memory Formation
    • DOI 10.1016/j.neuron.2007.02.022, PII S0896627307001420
    • Miller CA, Sweatt JD (2007). Covalent modification of DNA regulates memory formation. Neuron 53: 857-869. (Pubitemid 46367557)
    • (2007) Neuron , vol.53 , Issue.6 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 92
    • 52249104915 scopus 로고    scopus 로고
    • Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia
    • Miniaci MC, Kim JH, Puthanveettil SV, Si K, Zhu H, Kandel ER et al. (2008). Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia. Neuron 59: 1024-1036.
    • (2008) Neuron , vol.59 , pp. 1024-1036
    • Miniaci, M.C.1    Kim, J.H.2    Puthanveettil, S.V.3    Si, K.4    Zhu, H.5    Kandel, E.R.6
  • 93
    • 33748587841 scopus 로고    scopus 로고
    • A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes
    • DOI 10.1016/j.cell.2006.07.031, PII S0092867406010993
    • Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, Thomson AM et al. (2006). A patternbased method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell 126: 1203-1217. (Pubitemid 44380294)
    • (2006) Cell , vol.126 , Issue.6 , pp. 1203-1217
    • Miranda, K.C.1    Huynh, T.2    Tay, Y.3    Ang, Y.-S.4    Tam, W.-L.5    Thomson, A.M.6    Lim, B.7    Rigoutsos, I.8
  • 94
    • 12744261491 scopus 로고    scopus 로고
    • Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome
    • Moretti P, Bouwknecht JA, Teague R, Paylor R, Zoghbi HY (2005). Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome. Hum Mol Genet 14: 205-220.
    • (2005) Hum Mol Genet , vol.14 , pp. 205-220
    • Moretti, P.1    Bouwknecht, J.A.2    Teague, R.3    Paylor, R.4    Zoghbi, H.Y.5
  • 96
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
    • DOI 10.1016/S0092-8674(00)81887-5
    • Nan X, Campoy FJ, Bird A (1997). MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88: 471-481. (Pubitemid 27154412)
    • (1997) Cell , vol.88 , Issue.4 , pp. 471-481
    • Xinsheng, N.1    Campoy, F.J.2    Bird, A.3
  • 97
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • DOI 10.1038/30764
    • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN et al. (1998). Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393: 386-389. (Pubitemid 28269714)
    • (1998) Nature , vol.393 , Issue.6683 , pp. 386-389
    • Nan, X.1    Ng, H.-H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 99
    • 0030606239 scopus 로고    scopus 로고
    • The transcriptional coactivators p300 and CBP are histone acetyltransferases
    • DOI 10.1016/S0092-8674(00)82001-2
    • Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y (1996). The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87: 953-959. (Pubitemid 26404293)
    • (1996) Cell , vol.87 , Issue.5 , pp. 953-959
    • Ogryzko, V.V.1    Schiltz, R.L.2    Russanova, V.3    Howard, B.H.4    Nakatani, Y.5
  • 101
    • 33645080930 scopus 로고    scopus 로고
    • Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice
    • Pelka GJ, Watson CM, Radziewic T, Hayward M, Lahooti H, Christodoulou J et al. (2006). Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice. Brain 129: 887-898.
    • (2006) Brain , vol.129 , pp. 887-898
    • Pelka, G.J.1    Watson, C.M.2    Radziewic, T.3    Hayward, M.4    Lahooti, H.5    Christodoulou, J.6
  • 104
    • 80052560599 scopus 로고    scopus 로고
    • Age-related changes in Arc transcription and DNA methylation within the hippocampus
    • doi:10.1016/j.neurobiolaging.2010.01.009
    • Penner MR, Roth TL, Chawla MK, Hoang LT, Roth ED, Lubin FD et al. (2010b). Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol Aging. doi:10.1016/j.neurobiolaging.2010.01.009.
    • (2010) Neurobiol Aging.
    • Penner, M.R.1    Roth, T.L.2    Chawla, M.K.3    Hoang, L.T.4    Roth, E.D.5    Lubin, F.D.6
  • 105
    • 0029022770 scopus 로고
    • Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
    • Petrij F, Giles RH, Dauwerse HG, Saris JJ, Hennekam RC, Masuno M et al. (1995). Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 376: 348-351.
    • (1995) Nature , vol.376 , pp. 348-351
    • Petrij, F.1    Giles, R.H.2    Dauwerse, H.G.3    Saris, J.J.4    Hennekam, R.C.5    Masuno, M.6
  • 106
    • 33845956755 scopus 로고
    • Effects of amino acid feedings in schizophrenic patients treated with iproniazid
    • Pollin W, Cardon Jr PV, Kety SS (1961). Effects of amino acid feedings in schizophrenic patients treated with iproniazid. Science 133: 104-105.
    • (1961) Science , vol.133 , pp. 104-105
    • Pollin, W.1    Cardon Jr., P.V.2    Kety, S.S.3
  • 107
    • 77952585703 scopus 로고    scopus 로고
    • MicroRNAs as a molecular basis for mental retardation, Alzheimer's and prion diseases
    • Provost P (2010). MicroRNAs as a molecular basis for mental retardation, Alzheimer's and prion diseases. Brain Res 1338: 58-66.
    • (2010) Brain Res , vol.1338 , pp. 58-66
    • Provost, P.1
  • 109
    • 0019398578 scopus 로고
    • DNA methylation and its possible biological roles
    • Razin A, Friedman J (1981). DNA methylation and its possible biological roles. Prog Nucleic Acid Res Mol Biol 25: 33-52.
    • (1981) Prog Nucleic Acid Res Mol Biol , vol.25 , pp. 33-52
    • Razin, A.1    Friedman, J.2
  • 110
    • 65549142573 scopus 로고    scopus 로고
    • Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins
    • Renthal W, Kumar A, Xiao G, Wilkinson M, Covington III HE, Maze I et al. (2009). Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron 62: 335-348.
    • (2009) Neuron , vol.62 , pp. 335-348
    • Renthal, W.1    Kumar, A.2    Xiao, G.3    Wilkinson, M.4    Covington Iii, H.E.5    Maze, I.6
  • 112
    • 48149096013 scopus 로고    scopus 로고
    • Epigenetic mechanisms in drug addiction
    • Renthal W, Nestler EJ (2008). Epigenetic mechanisms in drug addiction. Trends Mol Med 14: 341-350.
    • (2008) Trends Mol Med , vol.14 , pp. 341-350
    • Renthal, W.1    Nestler, E.J.2
  • 113
    • 70350619619 scopus 로고    scopus 로고
    • Cellular prion protein modulates age-related behavioral and neurochemical alterations in mice
    • Rial D, Duarte FS, Xikota JC, Schmitz AE, Dafre AL, Figueiredo CP et al. (2009). Cellular prion protein modulates age-related behavioral and neurochemical alterations in mice. Neuroscience 164: 896-907.
    • (2009) Neuroscience , vol.164 , pp. 896-907
    • Rial, D.1    Duarte, F.S.2    Xikota, J.C.3    Schmitz, A.E.4    Dafre, A.L.5    Figueiredo, C.P.6
  • 114
    • 33646193822 scopus 로고    scopus 로고
    • Inherited epigenetic variationFrevisiting soft inheritance
    • Richards EJ (2006). Inherited epigenetic variationFrevisiting soft inheritance. Nat Rev Genet 7: 395-401.
    • (2006) Nat Rev Genet , vol.7 , pp. 395-401
    • Richards, E.J.1
  • 115
    • 63449085750 scopus 로고    scopus 로고
    • Lasting epigenetic influence of early-life adversity on the BDNF gene
    • Roth TL, Lubin FD, Funk AJ, Sweatt JD (2009). Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol Psychiatry 65: 760-769.
    • (2009) Biol Psychiatry , vol.65 , pp. 760-769
    • Roth, T.L.1    Lubin, F.D.2    Funk, A.J.3    Sweatt, J.D.4
  • 119
    • 70449530489 scopus 로고    scopus 로고
    • Selective boosting of transcriptional and behavioral responses to drugs of abuse by histone deacetylase inhibition
    • Sanchis-Segura C, Lopez-Atalaya JP, Barco A (2009). Selective boosting of transcriptional and behavioral responses to drugs of abuse by histone deacetylase inhibition. Neuropsychopharmacology 34: 2642-2654.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2642-2654
    • Sanchis-Segura, C.1    Lopez-Atalaya, J.P.2    Barco, A.3
  • 120
    • 58149333252 scopus 로고    scopus 로고
    • L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice
    • Santini E, Alcacer C, Cacciatore S, Heiman M, Herve D, Greengard P et al. (2009). L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice. J Neurochem 108: 621-633.
    • (2009) J Neurochem , vol.108 , pp. 621-633
    • Santini, E.1    Alcacer, C.2    Cacciatore, S.3    Heiman, M.4    Herve, D.5    Greengard, P.6
  • 122
    • 71149121303 scopus 로고    scopus 로고
    • Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex
    • Schaefer A, Sampath SC, Intrator A, Min A, Gertler TS, Surmeier DJ et al. (2009). Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron 64: 678-691.
    • (2009) Neuron , vol.64 , pp. 678-691
    • Schaefer, A.1    Sampath, S.C.2    Intrator, A.3    Min, A.4    Gertler, T.S.5    Surmeier, D.J.6
  • 123
    • 79959813649 scopus 로고    scopus 로고
    • Every methyl counts-epigenetic calculus
    • doi:10.1016/j.febslet.2010.11.029
    • Scharf AN, Imhof A (2010). Every methyl counts-epigenetic calculus. FEBS Lett. doi:10.1016/j.febslet.2010.11.029.
    • (2010) FEBS Lett.
    • Scharf, A.N.1    Imhof, A.2
  • 125
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • DOI 10.1016/j.cell.2004.12.012, PII S0092867404011997
    • Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA et al. (2004). Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119: 941-953. (Pubitemid 40037608)
    • (2004) Cell , vol.119 , Issue.7 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3    Mulligan, P.4    Whetstine, J.R.5    Cole, P.A.6    Casero, R.A.7    Shi, Y.8
  • 126
    • 33846025127 scopus 로고    scopus 로고
    • Dynamic Regulation of Histone Lysine Methylation by Demethylases
    • DOI 10.1016/j.molcel.2006.12.010, PII S1097276506008689
    • Shi Y, Whetstine JR (2007). Dynamic regulation of histone lysine methylation by demethylases. Mol Cell 25: 1-14. (Pubitemid 46049067)
    • (2007) Molecular Cell , vol.25 , Issue.1 , pp. 1-14
    • Shi, Y.1    Whetstine, J.R.2
  • 127
    • 75749134925 scopus 로고    scopus 로고
    • Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation
    • Si K, Choi YB, White-Grindley E, Majumdar A, Kandel ER (2010). Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation. Cell 140: 421-435.
    • (2010) Cell , vol.140 , pp. 421-435
    • Si, K.1    Choi, Y.B.2    White-Grindley, E.3    Majumdar, A.4    Kandel, E.R.5
  • 128
    • 0346186101 scopus 로고    scopus 로고
    • A Neuronal Isoform of CPEB Regulates Local Protein Synthesis and Stabilizes Synapse-Specific Long-Term Facilitation in Aplysia
    • DOI 10.1016/S0092-8674(03)01021-3
    • Si K, Giustetto M, Etkin A, Hsu R, Janisiewicz AM, Miniaci MC et al. (2003a). A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia. Cell 115: 893-904. (Pubitemid 38058500)
    • (2003) Cell , vol.115 , Issue.7 , pp. 893-904
    • Si, K.1    Giustetto, M.2    Etkin, A.3    Hsu, R.4    Janisiewicz, A.M.5    Miniaci, M.C.6    Kim, J.-H.7    Zhu, H.8    Kandel, E.R.9
  • 129
    • 0348077417 scopus 로고    scopus 로고
    • A Neuronal Isoform of the Aplysia CPEB Has Prion-Like Properties
    • DOI 10.1016/S0092-8674(03)01020-1
    • Si K, Lindquist S, Kandel ER (2003b). A neuronal isoform of the aplysia CPEB has prion-like properties. Cell 115: 879-891. (Pubitemid 38058499)
    • (2003) Cell , vol.115 , Issue.7 , pp. 879-891
    • Si, K.1    Lindquist, S.2    Kandel, E.R.3
  • 130
    • 33745862395 scopus 로고    scopus 로고
    • Crystal structure and mechanism of human lysine-specific demethylase-1
    • DOI 10.1038/nsmb1113, PII NSMB1113
    • Stavropoulos P, Blobel G, Hoelz A (2006). Crystal structure and mechanism of human lysine-specific demethylase-1. Nat Struct Mol Biol 13: 626-632. (Pubitemid 44036473)
    • (2006) Nature Structural and Molecular Biology , vol.13 , Issue.7 , pp. 626-632
    • Stavropoulos, P.1    Blobel, G.2    Hoelz, A.3
  • 131
    • 34247862140 scopus 로고    scopus 로고
    • Behavioral and anatomical abnormalities in Mecp2 mutant mice: A model for Rett syndrome
    • DOI 10.1016/j.neuroscience.2007.02.009, PII S0306452207001820
    • Stearns NA, Schaevitz LR, Bowling H, Nag N, Berger UV, Berger-Sweeney J (2007). Behavioral and anatomical abnormalities in Mecp2 mutant mice: a model for Rett syndrome. Neuroscience 146: 907-921. (Pubitemid 46694130)
    • (2007) Neuroscience , vol.146 , Issue.3 , pp. 907-921
    • Stearns, N.A.1    Schaevitz, L.R.2    Bowling, H.3    Nag, N.4    Berger, U.V.5    Berger-Sweeney, J.6
  • 134
    • 0035873614 scopus 로고    scopus 로고
    • Increased histone acetyltransferase and lysine acetyltransferase activity and biphasic activation of the ERK/RSK cascade in insular cortex during novel taste learning
    • Swank MW, Sweatt JD (2001). Increased histone acetyltransferase and lysine acetyltransferase activity and biphasic activation of the ERK/RSK cascade in insular cortex during novel taste learning. J Neurosci 21: 3383-3391. (Pubitemid 32427673)
    • (2001) Journal of Neuroscience , vol.21 , Issue.10 , pp. 3383-3391
    • Swank, M.W.1    Sweatt, J.D.2
  • 135
    • 65249157050 scopus 로고    scopus 로고
    • Epigenetics, DNA methylation, and chromatin modifying drugs
    • Szyf M (2009). Epigenetics, DNA methylation, and chromatin modifying drugs. Annu Rev Pharmacol Toxicol 49: 243-263.
    • (2009) Annu Rev Pharmacol Toxicol , vol.49 , pp. 243-263
    • Szyf, M.1
  • 136
    • 54349095323 scopus 로고    scopus 로고
    • G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription
    • Tachibana M, Matsumura Y, Fukuda M, Kimura H, Shinkai Y (2008). G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J 27: 2681-2690.
    • (2008) EMBO J , vol.27 , pp. 2681-2690
    • Tachibana, M.1    Matsumura, Y.2    Fukuda, M.3    Kimura, H.4    Shinkai, Y.5
  • 137
    • 0035816682 scopus 로고    scopus 로고
    • Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3
    • Tachibana M, Sugimoto K, Fukushima T, Shinkai Y (2001). Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. J Biol Chem 276: 25309-25317.
    • (2001) J Biol Chem , vol.276 , pp. 25309-25317
    • Tachibana, M.1    Sugimoto, K.2    Fukushima, T.3    Shinkai, Y.4
  • 139
  • 141
    • 70449725209 scopus 로고    scopus 로고
    • Epigenetic mechanisms in neurological diseases: Genes, syndromes, and therapies
    • Urdinguio RG, Sanchez-Mut JV, Esteller M (2009). Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol 8: 1056-1072.
    • (2009) Lancet Neurol , vol.8 , pp. 1056-1072
    • Urdinguio, R.G.1    Sanchez-Mut, J.V.2    Esteller, M.3
  • 142
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan S, Tong Y, Steitz JA (2007). Switching from repression to activation: microRNAs can up-regulate translation. Science 318: 1931-1934.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 147
    • 28044436691 scopus 로고    scopus 로고
    • Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: Altering epigenetic marking later in life
    • DOI 10.1523/JNEUROSCI.3652-05.2005
    • Weaver IC, Champagne FA, Brown SE, Dymov S, Sharma S, Meaney MJ et al. (2005). Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci 25: 11045-11054. (Pubitemid 41692634)
    • (2005) Journal of Neuroscience , vol.25 , Issue.47 , pp. 11045-11054
    • Weaver, I.C.G.1    Champagne, F.A.2    Brown, S.E.3    Dymov, S.4    Sharma, S.5    Meaney, M.J.6    Szyf, M.7
  • 148
    • 23044514626 scopus 로고    scopus 로고
    • Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
    • DOI 10.1038/ng1598
    • Weber M, Davies JJ, Wittig D, Oakeley EJ, Haase M, Lam WL et al. (2005). Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet 37: 853-862. (Pubitemid 41077111)
    • (2005) Nature Genetics , vol.37 , Issue.8 , pp. 853-862
    • Weber, M.1    Davies, J.J.2    Wittig, D.3    Oakeley, E.J.4    Haase, M.5    Lam, W.L.6    Schubeler, D.7
  • 149
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
    • DOI 10.1038/ng1990, PII NG1990
    • Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, Rebhan M et al. (2007). Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 39: 457-466. (Pubitemid 46514772)
    • (2007) Nature Genetics , vol.39 , Issue.4 , pp. 457-466
    • Weber, M.1    Hellmann, I.2    Stadler, M.B.3    Ramos, L.4    Paabo, S.5    Rebhan, M.6    Schubeler, D.7
  • 150
    • 77956095231 scopus 로고    scopus 로고
    • Active DNA demethylation: Many roads lead to Rome
    • Wu SC, Zhang Y (2010). Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol 11: 607-620.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 607-620
    • Wu, S.C.1    Zhang, Y.2
  • 151
    • 34547730282 scopus 로고    scopus 로고
    • A Histone H2A Deubiquitinase Complex Coordinating Histone Acetylation and H1 Dissociation in Transcriptional Regulation
    • DOI 10.1016/j.molcel.2007.07.024, PII S1097276507005163
    • Zhu P, Zhou W, Wang J, Puc J, Ohgi KA, Erdjument-Bromage H et al. (2007). A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. Mol Cell 27: 609-621. (Pubitemid 47238636)
    • (2007) Molecular Cell , vol.27 , Issue.4 , pp. 609-621
    • Zhu, P.1    Zhou, W.2    Wang, J.3    Puc, J.4    Ohgi, K.A.5    Erdjument-Bromage, H.6    Tempst, P.7    Glass, C.K.8    Rosenfeld, M.G.9
  • 152
    • 67349198048 scopus 로고    scopus 로고
    • An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes
    • Zhubi A, Veldic M, Puri NV, Kadriu B, Caruncho H, Loza I et al. (2009). An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes. Schizophr Res 111: 115-122.
    • (2009) Schizophr Res , vol.111 , pp. 115-122
    • Zhubi, A.1    Veldic, M.2    Puri, N.V.3    Kadriu, B.4    Caruncho, H.5    Loza, I.6


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