Valproate induces DNA demethylation in nuclear extracts from adult mouse brain

Epigenetics

Volumn 5, Issue 8, 2010, Pages 730-735

  Dong, Erbo ^a   Chen, Ying ^a   Gavin, David P ^a   Grayson, Dennis R ^a   Guidotti, Alessandro ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

DNA demethylase; HDAC inhibitors; Mouse frontal cortex; Reelin (Reln) promoter; Valproate (VPA)

Indexed keywords

GLUTAMATE DECARBOXYLASE 67; MESSENGER RNA; REELIN; VALPROIC ACID; ANTICONVULSIVE AGENT; DNA METHYLTRANSFERASE; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; REELIN PROTEIN; SCLEROPROTEIN; SERINE PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BIPOLAR DISORDER; COGNITIVE DEFECT; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; FRONTAL CORTEX; MALE; MOUSE; NONHUMAN; SCHIZOPHRENIA; SOUTHERN BLOTTING; UPREGULATION; ANIMAL; BIOSYNTHESIS; BRAIN; CELL NUCLEUS; CHEMICALLY INDUCED DISORDER; CPG ISLAND; DEGENERATIVE DISEASE; DRUG EFFECT; GENETICS; GLIA; MENTAL DISEASE; METABOLISM; NERVE CELL; PROMOTER REGION;

MAMMALIA; MUS;

ANIMALS; ANTICONVULSANTS; BRAIN; CELL ADHESION MOLECULES, NEURONAL; CELL NUCLEUS; CPG ISLANDS; DNA METHYLATION; DNA MODIFICATION METHYLASES; EXTRACELLULAR MATRIX PROTEINS; MALE; MENTAL DISORDERS; MICE; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEUROGLIA; NEURONS; PROMOTER REGIONS, GENETIC; SERINE ENDOPEPTIDASES; VALPROIC ACID;

EID: 78449250771     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.5.8.13053     Document Type: Article

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