Ganoderic acid DM, a natural triterpenoid, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells

Fitoterapia

Volumn 83, Issue 2, 2012, Pages 408-414

  Wu, Guo Sheng ^a,b   Lu, Jin Jian ^a,b   Guo, Jia Jie ^a,b   Li, Ying Bo ^a,b   Tan, Wen ^a,b   Dang, Yuan Ye ^a,b   Zhong, Zhang Feng ^a,b   Xu, Zeng Tao ^a,b   Chen, Xiu Ping ^a,b   Wang, Yi Tao ^a,b  

^a China jack1987168 163com   (Macao)

^b University of Macau   (Macao)

Author keywords

Apoptosis; DNA damage; G1 cell cycle arrest; Ganoderic acid DM; MCF 7

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 6; GANODERIC ACID DM; GANODERMA LUCIDUM EXTRACT; HISTONE H2AX; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TRITERPENOID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL COUNT; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL VIABILITY; COLONY FORMATION; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; G1 PHASE CELL CYCLE CHECKPOINT; GANODERMA LUCIDUM; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; UPREGULATION;

APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; G1 PHASE CELL CYCLE CHECKPOINTS; HISTONES; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REISHI; STEM CELLS; TIME FACTORS; TRITERPENES; UP-REGULATION;

BASIDIOMYCOTA; GANODERMA LUCIDUM;

EID: 84855986840     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2011.12.004     Document Type: Article

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