메뉴 건너뛰기




Volumn 27, Issue 5, 2010, Pages 361-369

The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis

Author keywords

Anti invasion; Anti metastasis; Ganoderma lucidum; Polysaccharides; Triterpenoids

Indexed keywords

BETA1 INTEGRIN; GANODERMA LUCIDUM EXTRACT; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA1; UROKINASE; UROKINASE RECEPTOR; VASCULOTROPIN; PLANT EXTRACT;

EID: 77953924040     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-010-9334-z     Document Type: Review
Times cited : (94)

References (79)
  • 1
    • 0025256084 scopus 로고
    • Metastatic inefficiency
    • L Weiss 1990 Metastatic inefficiency Adv Cancer Res 54 159 211 10.1016/S0065-230X(08)60811-8 1:STN:280:DyaK3c7hvFSisw%3D%3D 1688681 (Pubitemid 20088338)
    • (1990) Advances in Cancer Research , vol.54 , pp. 159-211
    • Weiss, L.1
  • 2
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
    • 10.1016/0092-8674(91)90642-C 1:CAS:528:DyaK3MXpvFWktA%3D%3D 1703045
    • LA Liotta PS Steeg WG Stetter-Stevenson 1991 Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation Cell 64 327 336 10.1016/0092-8674(91)90642-C 1:CAS:528:DyaK3MXpvFWktA%3D%3D 1703045
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.A.1    Steeg, P.S.2    Stetter-Stevenson, W.G.3
  • 3
    • 0345059766 scopus 로고    scopus 로고
    • Intravital imaging of cell movement in tumours
    • J Condeelis JE Segall 2003 Intravital imaging of cell movement in tumours Nat Rev Cancer 3 921 930 10.1038/nrc1231 1:CAS:528:DC%2BD3sXpvFahsLc%3D 14737122 (Pubitemid 37500177)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 921-930
    • Condeelis, J.1    Segall, J.E.2
  • 4
    • 46749100200 scopus 로고    scopus 로고
    • Suppression of cancer invasiveness by dietary compounds
    • 10.2174/138955708784567412 1:CAS:528:DC%2BD1cXnslWkurw%3D 18537723
    • D Sliva 2008 Suppression of cancer invasiveness by dietary compounds Mini Rev Med Chem 8 677 688 10.2174/138955708784567412 1:CAS:528: DC%2BD1cXnslWkurw%3D 18537723
    • (2008) Mini Rev Med Chem , vol.8 , pp. 677-688
    • Sliva, D.1
  • 5
    • 0022533562 scopus 로고
    • Three new lanostanoids from Ganoderma lucidum
    • DOI 10.1021/np50046a010
    • M Aarisawa A Fujita M Saga, et al. 1986 Three new lanostanoids from Ganoderma lucidum J Nat Prod 49 621 625 10.1021/np50046a010 (Pubitemid 16001135)
    • (1986) Journal of Natural Products , vol.49 , Issue.4 , pp. 621-625
    • Arisawa, M.1    Fujita, A.2    Saga, M.3
  • 6
    • 30344462751 scopus 로고    scopus 로고
    • Chemopreventive and tumoricidal properties of Ling Zhi mushroom Ganoderma lucidum (W. Curt.: Fr.) Lloyd (Aphyllophoromycetideae). II. Mechanism considerations
    • 10.1615/IntJMedMushr.v6.i3.20 1:CAS:528:DC%2BD2cXos1ems7g%3D
    • YH Gao SF Zhou 2004 Chemopreventive and tumoricidal properties of Ling Zhi mushroom Ganoderma lucidum (W. Curt.: Fr.) Lloyd (Aphyllophoromycetideae). II. Mechanism considerations Int J Med Mushrooms 6 219 230 10.1615/IntJMedMushr. v6.i3.20 1:CAS:528:DC%2BD2cXos1ems7g%3D
    • (2004) Int J Med Mushrooms , vol.6 , pp. 219-230
    • Gao, Y.H.1    Zhou, S.F.2
  • 7
    • 16544395588 scopus 로고    scopus 로고
    • Quantitative determination of bitter principles in specimens of Ganoderma lucidum using high-performance liquid chromatography and its application to the evaluation of Ganoderma products
    • DOI 10.1248/cpb.52.688
    • JJ Gao N Nakamura BS Min, et al. 2004 Quantitative determination of bitter principles in specimens of Ganoderma lucidum using high-performance liquid chromatography and its application to the evaluation of Ganoderma products Chem Pharm Bull 52 688 695 10.1248/cpb.52.688 1:CAS:528: DC%2BD2cXltFKqs7o%3D 15187388 (Pubitemid 41685505)
    • (2004) Chemical and Pharmaceutical Bulletin , vol.52 , Issue.6 , pp. 688-695
    • Gao, J.-J.1    Nakamura, N.2    Min, B.-S.3    Hirakawa, A.4    Zuo, F.5    Hattori, M.6
  • 8
    • 8544228336 scopus 로고    scopus 로고
    • Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms
    • ZB Lin HN Zhang 2004 Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms Acta Pharmacol Sin 25 1387 1395 1:CAS:528:DC%2BD2cXpvVCjsbY%3D 15525457 (Pubitemid 39490882)
    • (2004) Acta Pharmacologica Sinica , vol.25 , Issue.11 , pp. 1387-1395
    • Lin, Z.-B.1    Zhang, H.-N.2
  • 9
    • 12844276589 scopus 로고    scopus 로고
    • Lipocalins in drug discovery: From natural ligand-binding proteins to 'anticalins'
    • DOI 10.1016/S1359-6446(04)03294-5, PII S1359644604032945
    • N Johnston 2005 Medicinal mushroom cuts off prostate cancer cells' blood supply Drug Discov Today 10 23 24 10.1016/S1359-6446(04)03294-5 (Pubitemid 40164816)
    • (2005) Drug Discovery Today , vol.10 , Issue.1 , pp. 23-33
    • Schlehuber, S.1    Skerra, A.2
  • 10
    • 22744436323 scopus 로고    scopus 로고
    • Mechanisms of the anticancer action of Ganoderma lucidum (Leyss. ex Fr.) Karst.: A new understanding
    • DOI 10.1111/j.1744-7909.2005.00037.x
    • GQ Liu KC Zhang 2005 Mechanisms of the anticancer action of Ganoderma lucidum (Leyss. Ex Fr.) Karst.: A new understanding J Integr Plant Biol 47 129 135 10.1111/j.1744-7909.2005.00037.x 1:CAS:528:DC%2BD28Xpt1ymtw%3D%3D (Pubitemid 41029910)
    • (2005) Journal of Integrative Plant Biology , vol.47 , Issue.2 , pp. 129-135
    • Liu, G.-Q.1    Zhang, K.-C.2
  • 11
    • 30344482855 scopus 로고    scopus 로고
    • Anticancer effects of Ganoderma lucidum: A review of scientific evidence
    • DOI 10.1207/s15327914nc5301-2
    • JWM Yuen MDI Gohel 2005 Anticancer effects of Ganoderma lucidum: a review of scientific evidence Nutr Cancer 53 11 17 10.1207/s15327914nc5301-2 1:CAS:528:DC%2BD28XptF2ksQ%3D%3D 16351502 (Pubitemid 43068549)
    • (2005) Nutrition and Cancer , vol.53 , Issue.1 , pp. 11-17
    • Yuen, J.W.M.1    Gohel, M.D.I.2
  • 12
    • 33748091693 scopus 로고    scopus 로고
    • Ganoderma - A therapeutic fungal biofactory
    • DOI 10.1016/j.phytochem.2006.07.004, PII S0031942206004080
    • RR Paterson 2006 Ganoderma-a therapeutic fungal biofactory Phytochemistry 67 1985 2001 10.1016/j.phytochem.2006.07.004 1:CAS:528:DC%2BD28XptFCgt7k%3D 16905165 (Pubitemid 44301285)
    • (2006) Phytochemistry , vol.67 , Issue.18 , pp. 1985-2001
    • Paterson, R.R.M.1
  • 13
    • 33646029098 scopus 로고    scopus 로고
    • Ganoderma lucidum extract inhibits proliferation of SW 480 human colorectal cancer cells
    • 1:CAS:528:DC%2BD28Xltlakt7o%3D 16614703
    • JT Xie CZ Wang S Wicks, et al. 2006 Ganoderma lucidum extract inhibits proliferation of SW 480 human colorectal cancer cells Exp Oncol 28 25 29 1:CAS:528:DC%2BD28Xltlakt7o%3D 16614703
    • (2006) Exp Oncol , vol.28 , pp. 25-29
    • Xie, J.T.1    Wang, C.Z.2    Wicks, S.3
  • 14
    • 15444362990 scopus 로고    scopus 로고
    • Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-β1 from prostate cancer cells
    • DOI 10.1016/j.bbrc.2005.02.116
    • G Stanley K Harvey V Slivova, et al. 2005 Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-b1 from prostate cancer cells Biochem Biophys Res Commun 330 46 52 10.1016/j.bbrc.2005. 02.116 1:CAS:528:DC%2BD2MXisVCnu7c%3D 15781230 (Pubitemid 40394934)
    • (2005) Biochemical and Biophysical Research Communications , vol.330 , Issue.1 , pp. 46-52
    • Stanley, G.1    Harvey, K.2    Slivova, V.3    Jiang, J.4    Sliva, D.5
  • 15
    • 0036479114 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and NF-κB regulate motility of invasive MDA-MB-231 human breast cancer cells by the secretion of urokinase-type plasminogen activator
    • DOI 10.1074/jbc.M109579200
    • D Sliva D Rizzo 2002 Phosphatidylinositol 3-kinase and NF-κB regulate motility of invasive MDA-MB-231 human breast cancer cells by the secretion of urokinase-type plasminogen activator J Biol Chem 277 3150 3157 10.1074/jbc.M109579200 1:CAS:528:DC%2BD38XhtVaks74%3D 11689575 (Pubitemid 34953176)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.5 , pp. 3150-3157
    • Sliva, D.1    Rizzo, M.T.2    English, D.3
  • 16
    • 12444286118 scopus 로고    scopus 로고
    • The effective application of Ganoderma nutriceuticals
    • B.K. Kim C.K. Moon T.S. Kim (eds). The Pharmaceutical Society of Korea Seoul
    • Teow SS (1997) The effective application of Ganoderma nutriceuticals. In: Kim BK, Moon CK, Kim TS (eds) Recent progress in Ganoderma lucidum research. The Pharmaceutical Society of Korea, Seoul
    • (1997) Recent Progress in Ganoderma Lucidum Research
    • Teow, S.S.1
  • 17
    • 0036169299 scopus 로고    scopus 로고
    • Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: Functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities
    • DOI 10.1016/S0968-0896(01)00377-7, PII S0968089601003777
    • YY Wang KH Khoo ST Chen, et al. 2002 Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi). Polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities Bioorgan Med Chem 10 1057 1062 10.1016/S0968-0896(01)00377-7 1:CAS:528:DC%2BD38XhtVKhsbg%3D (Pubitemid 34139921)
    • (2002) Bioorganic and Medicinal Chemistry , vol.10 , Issue.4 , pp. 1057-1062
    • Wang, Y.-Y.1    Khoo, K.-H.2    Chen, S.-T.3    Lin, C.-C.4    Wong, C.-H.5    Lin, C.-H.6
  • 18
    • 33044496272 scopus 로고    scopus 로고
    • The relationship between molecular structure and activity of Ganoderma acids
    • 1:CAS:528:DC%2BD38XptFSiu74%3D (in Chinese with an English abstract)
    • HL Yang KC Zhang 2002 The relationship between molecular structure and activity of Ganoderma acids J Wuxi Univ Light Ind 21 249 253 1:CAS:528:DC%2BD38XptFSiu74%3D (in Chinese with an English abstract)
    • (2002) J Wuxi Univ Light Ind , vol.21 , pp. 249-253
    • Yang, H.L.1    Zhang, K.C.2
  • 19
    • 0034043914 scopus 로고    scopus 로고
    • Immunomodulation and anti-cancer activity of polysaccharide-protein complexes
    • Ooi VE, Liu F (2000) Immunomodulation and anti-cancer activity of polysaccharideprotein complexes. Curr Med Chem 7:715-729 (Pubitemid 30366638)
    • (2000) Current Medicinal Chemistry , vol.7 , Issue.7 , pp. 715-729
    • Ooi, V.E.C.1    Liu, F.2
  • 20
    • 0037210695 scopus 로고    scopus 로고
    • Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides
    • DOI 10.1007/s00253-002-1076-7
    • Wasser SP (2002) Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol 60: 258-274 (Pubitemid 35352092)
    • (2003) Applied Microbiology and Biotechnology , vol.60 , Issue.3 , pp. 258-274
    • Wasser, S.1
  • 21
    • 30544431647 scopus 로고    scopus 로고
    • Medicinal mushrooms and cancer therapy: Translating a traditional practice into western medicine
    • 10.1353/pbm.2006.0034 1:CAS:528:DC%2BD28XkvF2nsL0%3D 16702701
    • R Sullivan JE Smith NJ Rowan 2006 Medicinal mushrooms and cancer therapy: translating a traditional practice into western medicine Perspect Biol Med 49 159 170 10.1353/pbm.2006.0034 1:CAS:528:DC%2BD28XkvF2nsL0%3D 16702701
    • (2006) Perspect Biol Med , vol.49 , pp. 159-170
    • Sullivan, R.1    Smith, J.E.2    Rowan, N.J.3
  • 22
    • 34447259740 scopus 로고    scopus 로고
    • Antitumor polysaccharides from mushrooms: A review on their isolation process, structural characteristics and antitumor activity
    • DOI 10.1016/j.tifs.2006.07.013, PII S0924224406002470
    • M Zhang SW Cui PCK Cheung, et al. 2007 Antitumor polysaccharides from mushrooms: a review of their isolation process, structural characteristics and antitumor activity Trends Food Sci Tech 18 4 19 10.1016/j.tifs.2006.07.013 (Pubitemid 44827599)
    • (2007) Trends in Food Science and Technology , vol.18 , Issue.1 , pp. 4-19
    • Zhang, M.1    Cui, S.W.2    Cheung, P.C.K.3    Wang, Q.4
  • 23
    • 0007357638 scopus 로고
    • Studies on constituents of higher fungi of Korea IXII. Antitumor components of the basidiocarp of Ganoderma lucidum
    • 1:CAS:528:DyaK3MXhs1Sgu7g%3D
    • JW Hyun EC Choi BK Kim 1990 Studies on constituents of higher fungi of Korea IXII. Antitumor components of the basidiocarp of Ganoderma lucidum Korean J Mycol 18 58 69 1:CAS:528:DyaK3MXhs1Sgu7g%3D
    • (1990) Korean J Mycol , vol.18 , pp. 58-69
    • Hyun, J.W.1    Choi, E.C.2    Kim, B.K.3
  • 24
    • 0034874038 scopus 로고    scopus 로고
    • Cytotoxicity of Ganoderma lucidum triterpenes
    • DOI 10.1021/np010115w
    • TS Wu LS Shi SC Kuo 2001 Cytotoxicity of Ganoderma lucidum triterpenes J Nat Prod 64 1121 1122 10.1021/np010115w 1:CAS:528:DC%2BD3MXlsFGls7g%3D 11520245 (Pubitemid 32800357)
    • (2001) Journal of Natural Products , vol.64 , Issue.8 , pp. 1121-1122
    • Wu, T.-S.1    Shi, L.-S.2    Kuo, S.-C.3
  • 25
    • 33847745780 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidum
    • DOI 10.1002/cbdv.200790027
    • T Akihisa Y Nakamura M Tagata, et al. 2007 Ani-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidum Chem Biodivers 4 224 231 10.1002/cbdv.200790027 1:CAS:528:DC%2BD2sXisVyhu7k%3D 17311233 (Pubitemid 46929192)
    • (2007) Chemistry and Biodiversity , vol.4 , Issue.2 , pp. 224-231
    • Akihisa, T.1    Nakamura, Y.2    Tagata, M.3    Tokuda, H.4    Yasukawa, K.5    Uchiyama, E.6    Suzuki, T.7    Kimura, Y.8
  • 26
    • 43949104785 scopus 로고    scopus 로고
    • Development of a chromatographic fingerprint for the chloroform extracts of Ganoderma lucidum by HPLC and LC-MS
    • 10.1016/j.jpba.2008.01.039 1:CAS:528:DC%2BD1cXmtlyitr4%3D 18337046
    • Y Chen Y Yan MY Xie, et al. 2008 Development of a chromatographic fingerprint for the chloroform extracts of Ganoderma lucidum by HPLC and LC-MS J Pharm Biomed Anal 47 469 477 10.1016/j.jpba.2008.01.039 1:CAS:528: DC%2BD1cXmtlyitr4%3D 18337046
    • (2008) J Pharm Biomed Anal , vol.47 , pp. 469-477
    • Chen, Y.1    Yan, Y.2    Xie, M.Y.3
  • 27
    • 0141720419 scopus 로고    scopus 로고
    • Natural products of the medicinal fungus Ganoderma lucidum: Occurrence, biological activities, and pharmacological functions
    • DOI 10.1002/tcr.10058
    • MS Shiao 2003 Natural products of the medicinal fungus Ganoderma lucidum: occurrence, biological activities, and pharmacological functions Chem Rec 3 172 180 10.1002/tcr.10058 1:CAS:528:DC%2BD3sXmvVeku7s%3D 12900937 (Pubitemid 38569308)
    • (2003) Chemical Record , vol.3 , Issue.3 , pp. 172-180
    • Shiao, M.-S.1
  • 28
    • 0344393559 scopus 로고    scopus 로고
    • Ganoderma lucidum (Reishi) in Cancer Treatment
    • DOI 10.1177/1534735403259066
    • D Sliva 2003 Ganoderma lucidum (Reishi) in cancer treatment Integr Cancer Ther 2 358 364 10.1177/1534735403259066 14713328 (Pubitemid 37444432)
    • (2003) Integrative Cancer Therapies , vol.2 , Issue.4 , pp. 358-364
    • Sliva, D.1
  • 29
    • 33744519397 scopus 로고    scopus 로고
    • Ganoderma lucidum in cancer research
    • DOI 10.1016/j.leukres.2005.12.015, PII S0145212606000129
    • D Sliva 2006 Ganoderma lucidum in cancer research Leuk Res 30 767 768 10.1016/j.leukres.2005.12.015 16458355 (Pubitemid 43816705)
    • (2006) Leukemia Research , vol.30 , Issue.7 , pp. 767-768
    • Sliva, D.1
  • 30
    • 33748091693 scopus 로고    scopus 로고
    • Ganoderma - A therapeutic fungal biofactory
    • DOI 10.1016/j.phytochem.2006.07.004, PII S0031942206004080
    • R Russell M Paterson 2006 Ganoderma-A therapeutic fungal biofactory Phytochemistry 67 1985 2001 10.1016/j.phytochem.2006.07.004 (Pubitemid 44301285)
    • (2006) Phytochemistry , vol.67 , Issue.18 , pp. 1985-2001
    • Paterson, R.R.M.1
  • 31
    • 0002724305 scopus 로고
    • Antitumor effects of Ganoderma lucidum
    • SS Lee YH Wei CF Chen, et al. 1995 Antitumor effects of Ganoderma lucidum J Chin Med 6 1 12
    • (1995) J Chin Med , vol.6 , pp. 1-12
    • Lee, S.S.1    Wei, Y.H.2    Chen, C.F.3
  • 32
    • 45849099048 scopus 로고    scopus 로고
    • Effects of the antlered form of Ganoderma lucidum on tumor growth and metastasis in cyclophosphamide-treated mice
    • DOI 10.1271/bbb.70607
    • Y Nonaka H Ishibashi M Nakai, et al. 2008 Effects of the antlered form of Ganoderma lucidum on tumor growth and metastasis in cyclophosphamide-treated mice Biosci Biotechnol Biochem 72 1399 1408 10.1271/bbb.70607 1:CAS:528:DC%2BD1cXotlylu7c%3D 18540114 (Pubitemid 351883775)
    • (2008) Bioscience, Biotechnology and Biochemistry , vol.72 , Issue.6 , pp. 1399-1408
    • Nonaka, Y.1    Ishibashi, H.2    Nakai, M.3    Shibata, H.4    Kiso, Y.5    Abe, S.6
  • 33
    • 0034098326 scopus 로고    scopus 로고
    • Immunosuppressive drugs: The first 50 years and a glance forward
    • DOI 10.1016/S0162-3109(00)00186-7, PII S0162310900001867
    • AC Allison 2000 Immunosuppressive drugs: the first 50 years and a glance forward Immunopharmacology 47 63 83 10.1016/S0162-3109(00)00186-7 1:CAS:528:DC%2BD3cXktlKkt70%3D 10878284 (Pubitemid 30394533)
    • (2000) Immunopharmacology , vol.47 , Issue.2-3 , pp. 63-83
    • Allison, A.C.1
  • 36
    • 8444233557 scopus 로고    scopus 로고
    • Ganoderma lucidum inhibits invasiveness of breast cancer cells
    • V Slivova T Valachovicova J Jiang, et al. 2004 Ganoderma lucidum inhibits invasiveness of breast cancer cells J Cancer Integr Med 2 25 30
    • (2004) J Cancer Integr Med , vol.2 , pp. 25-30
    • Slivova, V.1    Valachovicova, T.2    Jiang, J.3
  • 37
    • 34247871452 scopus 로고    scopus 로고
    • Combined effect of green tea and Ganoderma lucidum on invasive behavior of breast cancer cells
    • 1:CAS:528:DC%2BD2sXkt1Whtb4%3D 17332936
    • A Thyagarajan J Zhu D Sliva 2007 Combined effect of green tea and Ganoderma lucidum on invasive behavior of breast cancer cells Int J Oncol 30 963 969 1:CAS:528:DC%2BD2sXkt1Whtb4%3D 17332936
    • (2007) Int J Oncol , vol.30 , pp. 963-969
    • Thyagarajan, A.1    Zhu, J.2    Sliva, D.3
  • 38
    • 33846240738 scopus 로고    scopus 로고
    • Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion
    • 1:CAS:528:DC%2BD28XhtV2rt7%2FO
    • A Thyagarajan J Jiang A Hopf, et al. 2006 Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion Intl J Mol Med 18 657 664 1:CAS:528:DC%2BD28XhtV2rt7%2FO
    • (2006) Intl J Mol Med , vol.18 , pp. 657-664
    • Thyagarajan, A.1    Jiang, J.2    Hopf, A.3
  • 39
    • 0346492926 scopus 로고    scopus 로고
    • Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum
    • DOI 10.1016/j.jep.2003.09.006
    • YS Song SH Kim JH Sa, et al. 2004 Anti-angiogenesis and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum J Ethnopharmacol 90 17 20 10.1016/j.jep.2003.09.006 14698502 (Pubitemid 38091679)
    • (2004) Journal of Ethnopharmacology , vol.90 , Issue.1 , pp. 17-20
    • Song, Y.S.1    Kim, S.-H.2    Sa, J.-H.3    Jin, C.4    Lim, C.-J.5    Park, E.-H.6
  • 40
    • 1442334390 scopus 로고    scopus 로고
    • Biologically Active Compounds from Aphyllophorales (Polypore) Fungi
    • DOI 10.1021/np030372w
    • JK Zjawiony 2004 Biologically active compounds from Aphyllophorales (Polypore) fungi J Nat Prod 67 300 310 10.1021/np030372w 1:CAS:528: DC%2BD2cXmtFWltg%3D%3D 14987072 (Pubitemid 38282922)
    • (2004) Journal of Natural Products , vol.67 , Issue.2 , pp. 300-310
    • Zjawiony, J.K.1
  • 41
    • 0026682524 scopus 로고
    • Medicinal benefits of the mushroom Ganoderma
    • 10.1016/S0065-2164(08)70253-3 1:CAS:528:DyaK3sXnt12iuw%3D%3D 1642155
    • SC Jong JM Birmingham 1992 Medicinal benefits of the mushroom Ganoderma Adv Appl Microbiol 37 101 134 10.1016/S0065-2164(08)70253-3 1:CAS:528: DyaK3sXnt12iuw%3D%3D 1642155
    • (1992) Adv Appl Microbiol , vol.37 , pp. 101-134
    • Jong, S.C.1    Birmingham, J.M.2
  • 42
    • 0001609016 scopus 로고
    • Natural products and biological activities of the chinese medicinal fungus Ganoderma lucidum
    • C.T. Ho T. Osawa M.T. Huang R.T. Rosen (eds). Oxford University Press Washington, DC
    • Shiao MS, Lee KR, Lin LJ et al. (1994) Natural products and biological activities of the chinese medicinal fungus Ganoderma lucidum. In: Ho CT, Osawa T, Huang MT, Rosen RT (eds) Food phytochemicals for cancer prevention II: teas, spices and herbs. Oxford University Press, Washington, DC
    • (1994) Food Phytochemicals for Cancer Prevention II: Teas, Spices and Herbs
    • Shiao, M.S.1    Lee, K.R.2    Lin, L.J.3
  • 43
    • 33846606129 scopus 로고    scopus 로고
    • Microwave-assisted extraction used for the isolation of total triterpenoid saponins from Ganoderma atrum
    • DOI 10.1016/j.jfoodeng.2006.10.018, PII S0260877406006522
    • Y Chen MY Xie XFJ Gong 2007 Microwave-assisted extraction used for the isolation of total triterpenoid saponins from Ganoderma atrum J Food Eng 81 162 170 10.1016/j.jfoodeng.2006.10.018 1:CAS:528:DC%2BD2sXjs1ymu7o%3D (Pubitemid 46176304)
    • (2007) Journal of Food Engineering , vol.81 , Issue.1 , pp. 162-170
    • Chen, Y.1    Xie, M.-Y.2    Gong, X.-F.3
  • 44
    • 84950000772 scopus 로고
    • Reishi, Ganoderma lucidum and Ganoderma tsugae: Bioactive substances and medicinal effects
    • 10.1080/87559129509541025 1:CAS:528:DyaK2MXltlKiu7o%3D
    • T Mizuno G Wang J Zhang, et al. 1995 Reishi, Ganoderma lucidum and Ganoderma tsugae: bioactive substances and medicinal effects Food Rev Int 11 151 166 10.1080/87559129509541025 1:CAS:528:DyaK2MXltlKiu7o%3D
    • (1995) Food Rev Int , vol.11 , pp. 151-166
    • Mizuno, T.1    Wang, G.2    Zhang, J.3
  • 45
    • 0033930342 scopus 로고    scopus 로고
    • Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against Meth-A and LLC tumor cells
    • BS Min JJ Gao N Nakamura, et al. 2000 Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells Chem Pharm Bull 48 1026 1033 1:CAS:528:DC%2BD3cXkslOnsb8%3D 10923835 (Pubitemid 30485402)
    • (2000) Chemical and Pharmaceutical Bulletin , vol.48 , Issue.7 , pp. 1026-1033
    • Min, B.-S.1    Gao, J.-J.2    Nakamura, N.3    Hattori, M.4
  • 46
    • 0038120144 scopus 로고    scopus 로고
    • Immune responses in cancer
    • DOI 10.1016/S0163-7258(03)00056-1
    • JK Adam B Odhav KD Bhoola 2003 Immune responses in cancer Food Rev Int 99 113 132 1:CAS:528:DC%2BD3sXksVegsrs%3D (Pubitemid 36700437)
    • (2003) Pharmacology and Therapeutics , vol.99 , Issue.1 , pp. 113-132
    • Adam, J.K.1    Odhav, B.2    Bhoola, K.D.3
  • 47
    • 2942539575 scopus 로고    scopus 로고
    • Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide
    • QZ Cao ZB Lin 2004 Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide Acta Pharmacol Sin 25 833 838 1:CAS:528:DC%2BD2cXkvVyqtLw%3D 15169641 (Pubitemid 38736114)
    • (2004) Acta Pharmacologica Sinica , vol.25 , Issue.6 , pp. 833-838
    • Cao, Q.-Z.1    Lin, Z.-B.2
  • 48
    • 3042526658 scopus 로고    scopus 로고
    • Immunomodulating activities of Ganoderma, a mushroom with medicinal properties
    • DOI 10.1081/FRI-120037158
    • YH Gao E Chan SF Zhou 2004 Immunomodulating activities of Ganoderma, a mushroom with medicinal properties Food Rev Int 20 123 161 10.1081/FRI-120037158 (Pubitemid 38805931)
    • (2004) Food Reviews International , vol.20 , Issue.2 , pp. 123-161
    • Gao, Y.1    Chan, E.2    Zhou, S.3
  • 49
    • 30344478630 scopus 로고    scopus 로고
    • Chemopreventive and tumoricidal properties of Lingzhi mushroom Ganoderma lucidum (W. Curt.:Fr.) Lloyd (Aphyllophorophoromycetideae). I. Preclinical and clinical studies (review)
    • 10.1615/IntJMedMushr.v6.i2.10 1:CAS:528:DC%2BD2cXlvVeqtrY%3D
    • YH Gao WB Tang H Gao, et al. 2004 Chemopreventive and tumoricidal properties of Lingzhi mushroom Ganoderma lucidum (W. Curt.:Fr.) Lloyd (Aphyllophorophoromycetideae). I. Preclinical and clinical studies (review) Int J Med Mushroom 6 95 106 10.1615/IntJMedMushr.v6.i2.10 1:CAS:528: DC%2BD2cXlvVeqtrY%3D
    • (2004) Int J Med Mushroom , vol.6 , pp. 95-106
    • Gao, Y.H.1    Tang, W.B.2    Gao, H.3
  • 50
    • 0036595422 scopus 로고    scopus 로고
    • New triterpene aldehydes, lucialdehydes A - C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells
    • DOI 10.1248/cpb.50.837
    • JJ Gao BS Min E Ahn, et al. 2002 New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells Chem Pharm Bull 50 837 840 10.1248/cpb.50.837 1:CAS:528: DC%2BD38XkvFOltLg%3D 12045343 (Pubitemid 41694906)
    • (2002) Chemical and Pharmaceutical Bulletin , vol.50 , Issue.6 , pp. 837-840
    • Gao, J.-J.1    Min, B.-S.2    Ahn, E.-M.3    Nakamura, N.4    Lee, H.-K.5    Hattori, M.6
  • 51
    • 27344459777 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum
    • DOI 10.1254/jphs.CRJ05008X
    • ZB Lin 2005 Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum J Pharmacol Sci 99 144 153 10.1254/jphs.CRJ05008X 1:CAS:528:DC%2BD2MXhtFOns7vM 16230843 (Pubitemid 41524452)
    • (2005) Journal of Pharmacological Sciences , vol.99 , Issue.2 , pp. 144-153
    • Lin, Z.-B.1
  • 52
    • 0037190124 scopus 로고    scopus 로고
    • Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum
    • DOI 10.1016/S0304-3835(02)00080-0, PII S0304383502000800
    • X Liu JP Yuan CK Chung, et al. 2002 Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum Cancer Lett 182 155 161 10.1016/S0304-3835(02)00080-0 1:CAS:528:DC%2BD38XktFKgsr0%3D 12048161 (Pubitemid 34621179)
    • (2002) Cancer Letters , vol.182 , Issue.2 , pp. 155-161
    • Liu, X.1    Yuan, J.-P.2    Chung, C.-K.3    Chen, X.-J.4
  • 53
    • 0001764973 scopus 로고
    • 13C-NMR correlation of stereochemistry in lanostanoids triterpenes
    • 10.1021/np50063a020 1:CAS:528:DyaK3cXnslGl
    • 13C-NMR correlation of stereochemistry in lanostanoids triterpenes J Nat Prod 52 595 605 10.1021/np50063a020 1:CAS:528:DyaK3cXnslGl
    • (1989) J Nat Prod , vol.52 , pp. 595-605
    • Lin, L.J.1    Shiao, M.S.2
  • 54
    • 0039596058 scopus 로고
    • A lanostanoid of formosan Ganoderma lucidum
    • 10.1016/0031-9422(90)85145-6 1:CAS:528:DyaK3cXhslGltbg%3D
    • CN Lin WP Tome SJ Won 1990 A lanostanoid of formosan Ganoderma lucidum Phytochemistry 29 673 675 10.1016/0031-9422(90)85145-6 1:CAS:528: DyaK3cXhslGltbg%3D
    • (1990) Phytochemistry , vol.29 , pp. 673-675
    • Lin, C.N.1    Tome, W.P.2    Won, S.J.3
  • 55
    • 0025913724 scopus 로고
    • Novel cytotoxic principles of formosan Ganoderma lucidum
    • 10.1021/np50076a012 1:CAS:528:DyaK38XjslGlug%3D%3D 1791484
    • CN Lin WP Tome 1991 Novel cytotoxic principles of formosan Ganoderma lucidum J Nat Prod 54 998 1002 10.1021/np50076a012 1:CAS:528: DyaK38XjslGlug%3D%3D 1791484
    • (1991) J Nat Prod , vol.54 , pp. 998-1002
    • Lin, C.N.1    Tome, W.P.2
  • 56
    • 0036871314 scopus 로고    scopus 로고
    • Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: Mechanism of action and isolation of an active substance
    • Y Kimura M Taniguchi K Baba 2002 Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance Anticancer Res 22 3309 3318 1:CAS:528:DC%2BD3sXoslyntw%3D%3D 12530080 (Pubitemid 36070107)
    • (2002) Anticancer Research , vol.22 , Issue.6 A , pp. 3309-3318
    • Kimura, Y.1    Taniguchi, M.2    Baba, K.3
  • 58
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • J Westermarck VM Kahari 1999 Regulation of matrix metalloproteinase expression in tumor invasion FASEB J 13 781 792 1:CAS:528:DyaK1MXjtFGksrs%3D 10224222 (Pubitemid 29220691)
    • (1999) FASEB Journal , vol.13 , Issue.8 , pp. 781-792
    • Westermarck, J.1    Kahari, V.-M.2
  • 59
    • 0041737535 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma invasiveness: The role of proteases
    • 10.1038/nrc1121 1:CAS:528:DC%2BD3sXltVSqtr8%3D 12835669
    • JS Rao 2003 Molecular mechanisms of glioma invasiveness: the role of proteases Nat Rev Cancer 3 489 501 10.1038/nrc1121 1:CAS:528: DC%2BD3sXltVSqtr8%3D 12835669
    • (2003) Nat Rev Cancer , vol.3 , pp. 489-501
    • Rao, J.S.1
  • 60
    • 0030938479 scopus 로고    scopus 로고
    • Matrix metalloproteinases as stromal effecters of human carcinoma progression: Therapeutic implications
    • DOI 10.1016/S0945-053X(97)90028-7
    • P Basset A Okada MP Chenard, et al. 1997 Matrix metalloproteinases as stromal effectors of human carcinoma progression: therapeutic implications Matrix Biol 15 535 541 10.1016/S0945-053X(97)90028-7 1:CAS:528: DyaK2sXjsVKisrs%3D 9138286 (Pubitemid 27190028)
    • (1997) Matrix Biology , vol.15 , Issue.8-9 , pp. 535-541
    • Basset, P.1    Okada, A.2    Chenard, M.-P.3    Kannan, R.4    Stoll, I.5    Anglard, P.6    Bellocq, J.-P.7    Rio, M.-C.8
  • 62
    • 0036915342 scopus 로고    scopus 로고
    • Enhanced expression of matrix metalloproteinase-9 by hepatitis B virus infection in liver cells
    • DOI 10.1016/S0003-9861(02)00522-2, PII S0003986102005222
    • TW Chung SK Moon YC Lee, et al. 2002 Enhanced expression of matrix metalloproteinase-9 by hepatitis B virus infection in liver cells Arch Biochem Biophys 408 147 154 10.1016/S0003-9861(02)00522-2 1:CAS:528:DC%2BD38XpsF2lu78%3D 12464265 (Pubitemid 36027033)
    • (2002) Archives of Biochemistry and Biophysics , vol.408 , Issue.2 , pp. 147-154
    • Chung, T.-W.1    Moon, S.-K.2    Lee, Y.-C.3    Kim, J.-G.4    Ko, J.-H.5    Kim, C.-H.6
  • 63
    • 0034933664 scopus 로고    scopus 로고
    • The urokinase plasminogen activator receptor (uPAR) as a target for the diagnosis and therapy of cancer
    • DOI 10.1097/00001813-200106000-00001
    • AP Mazar 2001 The urokinase plasminogen activator receptor (uPAR) as a target for the diagnosis and therapy of cancer Anticancer Drugs 12 387 400 10.1097/00001813-200106000-00001 1:CAS:528:DC%2BD3MXlsV2gs7g%3D 11395568 (Pubitemid 32643084)
    • (2001) Anti-Cancer Drugs , vol.12 , Issue.5 , pp. 387-400
    • Mazar, A.P.1
  • 64
    • 0014484140 scopus 로고
    • Antitumor activity of aqueous extracts of edible mushrooms
    • 1:STN:280:DyaF1M7jsVSntQ%3D%3D 5813100
    • T Ikekawa M Nakanishi N Uehara, et al. 1969 Antitumor activity of aqueous extracts of edible mushrooms Cancer Res 29 734 735 1:STN:280: DyaF1M7jsVSntQ%3D%3D 5813100
    • (1969) Cancer Res , vol.29 , pp. 734-735
    • Ikekawa, T.1    Nakanishi, M.2    Uehara, N.3
  • 65
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • J Folkman 1989 What is the evidence that tumor are angiogenesis dependent? J Natl Cancer Inst 82 4 6 10.1093/jnci/82.1.4 (Pubitemid 20020880)
    • (1990) Journal of the National Cancer Institute , vol.82 , Issue.1 , pp. 4-6
    • Folkman, J.1
  • 66
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • DOI 10.1038/362841a0
    • KJ Kim B Li J Winer, et al. 1993 Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo Nature 362 841 844 10.1038/362841a0 1:CAS:528:DyaK3sXktVKju7s%3D 7683111 (Pubitemid 23132159)
    • (1993) Nature , vol.362 , Issue.6423 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3    Armanini, M.4    Gillett, N.5    Phillips, H.S.6    Ferrara, N.7
  • 67
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • DOI 10.1038/367576a0
    • B Millauer LK Shawver KH Plate, et al. 1994 Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant Nature 367 576 579 10.1038/367576a0 1:CAS:528:DyaK2cXhs1Sgt7w%3D 8107827 (Pubitemid 2027191)
    • (1994) Nature , vol.367 , Issue.6463 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 68
    • 0043204317 scopus 로고    scopus 로고
    • Isoflavone aglycon produced by culture of soybean extracts with basidiomycetes and its anti-angiogenic activity
    • T Miura L Yuan B Sun, et al. 2002 Isoflavone aglycon produced by culture of soybean extracts with basidiomycetes and its anti-angiogenic activity Biosci Biotechnol Biochem 66 2626 2631 10.1271/bbb.66.2626 1:CAS:528: DC%2BD3sXht1Gqug%3D%3D 12596858 (Pubitemid 39251135)
    • (2002) Bioscience, Biotechnology and Biochemistry , vol.66 , Issue.12 , pp. 2626-2631
    • Miura, T.1    Yuan, L.2    Sun, B.3    Fujii, H.4    Yoshida, M.5    Wakame, K.6    Kosuna, K.-I.7
  • 70
    • 77954423846 scopus 로고    scopus 로고
    • Effect of Ganoderma lucidum polysaccharides peptide on invasion of human lung carcinoma cells in vitro
    • 1:CAS:528:DC%2BD1MXjtlegsQ%3D%3D 18087562
    • QZ Cao SQ Lin SZ Wang 2007 Effect of Ganoderma lucidum polysaccharides peptide on invasion of human lung carcinoma cells in vitro Beijing Da Xue Xue Bao 39 653 656 1:CAS:528:DC%2BD1MXjtlegsQ%3D%3D 18087562
    • (2007) Beijing da Xue Xue Bao , vol.39 , pp. 653-656
    • Cao, Q.Z.1    Lin, S.Q.2    Wang, S.Z.3
  • 71
    • 33751015787 scopus 로고    scopus 로고
    • Separation of targeted ganoderic acids from Ganoderma lucidum by reversed phase liquid chromatography with ultraviolet and mass spectrometry detections
    • DOI 10.1016/j.bej.2006.09.026, PII S1369703X06002737
    • W Tang TY Gu JJ Zhong 2006 Separation of targeted ganoderic acids from Ganoderma lucidum by reversed phase liquid chromatography with ultraviolet and mass spectrometry detections Biochem Eng J 32 205 210 10.1016/j.bej.2006.09.026 1:CAS:528:DC%2BD28Xht1CisLrP (Pubitemid 44751583)
    • (2006) Biochemical Engineering Journal , vol.32 , Issue.3 , pp. 205-210
    • Tang, W.1    Gu, T.2    Zhong, J.-J.3
  • 72
    • 34247353700 scopus 로고    scopus 로고
    • Enhancement of IL-2 and IFN-γ expression and NK cells activity involved in the anti-tumor effect of ganoderic acid Me in vivo
    • DOI 10.1016/j.intimp.2007.02.006, PII S1567576907000574
    • G Wang J Zhao JW Liu, et al. 2007 Enhancement of IL-2 and IFN-gamma expression and NK cells activity involved in the anti-tumor effect of ganoderic acid Me in vivo Int Immunopharmacol 7 864 870 10.1016/j.intimp.2007.02.006 1:CAS:528:DC%2BD2sXkslKqsLc%3D 17466920 (Pubitemid 46635284)
    • (2007) International Immunopharmacology , vol.7 , Issue.6 , pp. 864-870
    • Wang, G.1    Zhao, J.2    Liu, J.3    Huang, Y.4    Zhong, J.-J.5    Tang, W.6
  • 73
    • 55549103741 scopus 로고    scopus 로고
    • Ganoderic acid Me inhibits tumor invasion through down-regulating matrix metalloproteinases 2/9 gene expression
    • 10.1254/jphs.SC0080019 1:CAS:528:DC%2BD1cXhtlehs7%2FM 18946196
    • NH Chen JW Liu JJ Zhong 2008 Ganoderic acid Me inhibits tumor invasion through down-regulating matrix metalloproteinases 2/9 gene expression J Pharmacol Sci 108 212 216 10.1254/jphs.SC0080019 1:CAS:528:DC%2BD1cXhtlehs7%2FM 18946196
    • (2008) J Pharmacol Sci , vol.108 , pp. 212-216
    • Chen, N.H.1    Liu, J.W.2    Zhong, J.J.3
  • 74
    • 46449138184 scopus 로고    scopus 로고
    • Ganoderic acid suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling
    • 1:CAS:528:DC%2BD1cXmt1amtL4%3D 18425349
    • J Jiang B Grieb A Thyagarajan, et al. 2008 Ganoderic acid suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling Int J Mol Med 21 577 584 1:CAS:528:DC%2BD1cXmt1amtL4%3D 18425349
    • (2008) Int J Mol Med , vol.21 , pp. 577-584
    • Jiang, J.1    Grieb, B.2    Thyagarajan, A.3
  • 75
    • 77950818771 scopus 로고    scopus 로고
    • Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression
    • 20360625
    • NH Chen JW Liu JJ Zhong 2010 Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression Pharmacol Rep 62 150 163 20360625
    • (2010) Pharmacol Rep , vol.62 , pp. 150-163
    • Chen, N.H.1    Liu, J.W.2    Zhong, J.J.3
  • 76
    • 38049016812 scopus 로고    scopus 로고
    • The anti-invasive effects of lucidenic acids isolated from a new Ganoderma lucidum strain
    • 10.1002/mnfr.200700155 1:CAS:528:DC%2BD1cXhsFyqsg%3D%3D 17979098
    • CJ Weng CF Chau KD Chen, et al. 2007 The anti-invasive effects of lucidenic acids isolated from a new Ganoderma lucidum strain Mol Nutr Food Res 51 1472 1477 10.1002/mnfr.200700155 1:CAS:528:DC%2BD1cXhsFyqsg%3D%3D 17979098
    • (2007) Mol Nutr Food Res , vol.51 , pp. 1472-1477
    • Weng, C.J.1    Chau, C.F.2    Chen, K.D.3
  • 77
    • 6944253323 scopus 로고    scopus 로고
    • Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3
    • 1:CAS:528:DC%2BD2cXjvVGgu7s%3D 15067330
    • J Jiang V Slivova T Valachovicova, et al. 2004 Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3 Int J Oncol 24 1093 1100 1:CAS:528:DC%2BD2cXjvVGgu7s%3D 15067330
    • (2004) Int J Oncol , vol.24 , pp. 1093-1100
    • Jiang, J.1    Slivova, V.2    Valachovicova, T.3
  • 78
    • 38849178686 scopus 로고    scopus 로고
    • Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-κB and AP-1
    • DOI 10.1093/carcin/bgm261
    • CJ Weng CF Chau YS Hsieh, et al. 2008 Lucidenic acid inhibit PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kB and AP-1 Carcinogenesis 29 147 156 10.1093/carcin/bgm261 1:CAS:528:DC%2BD1cXhs1aisb8%3D 18024477 (Pubitemid 351201753)
    • (2008) Carcinogenesis , vol.29 , Issue.1 , pp. 147-156
    • Weng, C.-J.1    Chau, C.-F.2    Hsieh, Y.-S.3    Yang, S.-F.4    Yen, G.-C.5
  • 79
    • 67149099452 scopus 로고    scopus 로고
    • Inhibitory effects of Ganoderma lucidum on tumorigenesis and metastasis of human hepatoma cells in cells and animal models
    • 10.1021/jf900828k 1:CAS:528:DC%2BD1MXlsFKrsLw%3D 19422227
    • CJ Weng CF Chau GC Yen, et al. 2009 Inhibitory effects of Ganoderma lucidum on tumorigenesis and metastasis of human hepatoma cells in cells and animal models J Agric Food Chem 57 5049 5057 10.1021/jf900828k 1:CAS:528:DC%2BD1MXlsFKrsLw%3D 19422227
    • (2009) J Agric Food Chem , vol.57 , pp. 5049-5057
    • Weng, C.J.1    Chau, C.F.2    Yen, G.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.