Dl-3-n-butylphthalide extends survival by attenuating glial activation in a mouse model of amyotrophic lateral sclerosis

Neuropharmacology

Volumn 62, Issue 2, 2012, Pages 1004-1010

  Feng, Xinhong ^a,b   Peng, Ying ^c   Liu, Mingsheng ^a   Cui, Liying ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Amyotrophic lateral sclerosis; dl 3 n butylphthalide; Glial activation; Neuroinflammation; Oxidative stress; SOD1 G93A transgenic mouse

Indexed keywords

3 BUTYLPHTHALIDE; CD11B ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; HEME OXYGENASE 1; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL LOSS; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; IMMUNOREACTIVITY; MALE; MICROGLIA; MOTONEURON; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL TIME; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BENZOFURANS; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; MOTOR NEURONS; NEUROGLIA; NEUROPROTECTIVE AGENTS; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 84855964449     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.10.009     Document Type: Article

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