메뉴 건너뛰기




Volumn 32, Issue 4, 2010, Pages 390-396

3-n-butylphthalide (NBP) reduces apoptosis and enhances vascular endothelial growth factor (VEGF) up-regulation in diabetic rats

Author keywords

Apoptosis; Diabetes; Gliocytes; NBP; VEGF

Indexed keywords

3 BUTYLPHTHALIDE; CASPASE 3; CD11B ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE; STREPTOZOCIN; VASCULOTROPIN;

EID: 77952145041     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164110X12670144526264     Document Type: Article
Times cited : (73)

References (44)
  • 1
    • 33845498128 scopus 로고    scopus 로고
    • Effect of Mongolian plants on in vivo insulin action in diabetic rats
    • Khookhor O, Bolin Q, Oshida Y, et al. Effect of Mongolian plants on in vivo insulin action in diabetic rats. Diabetes Res Clin Pract 2007; 75: 135-140
    • (2007) Diabetes Res Clin Pract , vol.75 , pp. 135-140
    • Khookhor, O.1    Bolin, Q.2    Oshida, Y.3
  • 2
    • 0037327402 scopus 로고    scopus 로고
    • Oxidative stress and diabetic neuropathy: A new understanding of an old problem
    • Feldman EL. Oxidative stress and diabetic neuropathy: a new understanding of an old problem. J Clin Invest 2003; 111: 431-433
    • (2003) J Clin Invest , vol.111 , pp. 431-433
    • Feldman, E.L.1
  • 3
    • 0032572613 scopus 로고    scopus 로고
    • Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: Effects of insulin treatment
    • Biessels GJ, Kamal A, Urban IJ, et al. Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: Effects of insulin treatment. Brain Res 1998; 800: 125-135
    • (1998) Brain Res , vol.800 , pp. 125-135
    • Biessels, G.J.1    Kamal, A.2    Urban, I.J.3
  • 4
    • 67349254152 scopus 로고    scopus 로고
    • Exacerbation of poststroke dementia by type 2 diabetes is associated with synergistic increases of beta-secretase activation and beta-amyloid generation in rat brains
    • Zhang T, Pan BS, Zhao B, et al. Exacerbation of poststroke dementia by type 2 diabetes is associated with synergistic increases of beta-secretase activation and beta-amyloid generation in rat brains. Neuroscience 2009; 161: 1045-1056
    • (2009) Neuroscience , vol.161 , pp. 1045-1056
    • Zhang, T.1    Pan, B.S.2    Zhao, B.3
  • 5
    • 0033380583 scopus 로고    scopus 로고
    • Neurological changes induced by stress in streptozotocin diabetic rats
    • Reagan LP, Magarinos AM, Mcewen BS. Neurological changes induced by stress in streptozotocin diabetic rats. Ann NY Acad Sci 1999; 893: 126-137
    • (1999) Ann NY Acad Sci , vol.893 , pp. 126-137
    • Reagan, L.P.1    Magarinos, A.M.2    McEwen, B.S.3
  • 6
    • 0030829777 scopus 로고    scopus 로고
    • Apoptosis: An overview
    • Wyllie AH. Apoptosis: An overview. Br Med Bull 1997; 53: 451-465
    • (1997) Br Med Bull , vol.53 , pp. 451-465
    • Wyllie, A.H.1
  • 7
    • 12944250987 scopus 로고    scopus 로고
    • Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease
    • Hartmann A, Hunot S,Michel PP, et al. Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc Natl Acad Sci USA 2000; 97: 2875-2880
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2875-2880
    • Hartmann, A.1    Hunot, S.2    Michel, P.P.3
  • 8
    • 0034647003 scopus 로고    scopus 로고
    • Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
    • Li M, Ona VO, Guegan C, et al. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 2000; 288: 335-339
    • (2000) Science , vol.288 , pp. 335-339
    • Li, M.1    Ona, V.O.2    Guegan, C.3
  • 9
    • 0034733607 scopus 로고    scopus 로고
    • Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells
    • Wellington CL, Singaraja R, Ellerby L, et al. Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells. J Biol Chem 2000; 275: 19831-19838
    • (2000) J Biol Chem , vol.275 , pp. 19831-19838
    • Wellington, C.L.1    Singaraja, R.2    Ellerby, L.3
  • 10
    • 0033954672 scopus 로고    scopus 로고
    • Caspase-3 mediated neuronal death after traumatic brain injury in rats
    • Clark RS, Kochanek PM, Watkins SC, et al. Caspase-3 mediated neuronal death after traumatic brain injury in rats. J Neurochem 2000; 74: 740-753
    • (2000) J Neurochem , vol.74 , pp. 740-753
    • Clark, R.S.1    Kochanek, P.M.2    Watkins, S.C.3
  • 11
    • 0032918137 scopus 로고    scopus 로고
    • Caspases as treatment targets in stroke and neurodegenerative diseases
    • Schulz JB, Weller M, Moskowitz MA. Caspases as treatment targets in stroke and neurodegenerative diseases. Ann Neurol 1999; 45: 421-429
    • (1999) Ann Neurol , vol.45 , pp. 421-429
    • Schulz, J.B.1    Weller, M.2    Moskowitz, M.A.3
  • 12
    • 85047694286 scopus 로고    scopus 로고
    • VEGF: A critical player in neurodegeneration
    • Storkebaum E, Carmeliet P. VEGF: A critical player in neurodegeneration. J Clin Invest 2004; 113: 14-18
    • (2004) J Clin Invest , vol.113 , pp. 14-18
    • Storkebaum, E.1    Carmeliet, P.2
  • 13
    • 0032557564 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
    • DOI 10.1074/jbc.273.21.13313
    • Gerber HP, Dixit V, Ferrara N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 1998; 273: 13313-13316 (Pubitemid 28246905)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.21 , pp. 13313-13316
    • Gerber, H.-P.1    Dixit, V.2    Ferrara, N.3
  • 14
    • 0035842544 scopus 로고    scopus 로고
    • Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor
    • Jin K, Mao XO, Batteur SP, et al. Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor. Neuroscience 2001, 108: 351-358
    • (2001) Neuroscience , vol.108 , pp. 351-358
    • Jin, K.1    Mao, X.O.2    Batteur, S.P.3
  • 15
    • 33748110956 scopus 로고    scopus 로고
    • High plasma VEGF relates to low carbohydrate intake in patients with type 2 diabetes
    • Hubold C, Oltmanns KM, Schultes B, et al. High plasma VEGF relates to low carbohydrate intake in patients with type 2 diabetes. Int J Obes (Lond) 2006; 30: 1356-1361
    • (2006) Int J Obes (Lond) , vol.30 , pp. 1356-1361
    • Hubold, C.1    Oltmanns, K.M.2    Schultes, B.3
  • 16
    • 0029456321 scopus 로고
    • Protective effect of dl-3-n-butylphthalide on ischemic neurological damage and abnormal behavior in rats subjected to focal ischemia
    • Liu XG, Feng YP. [Protective effect of dl-3-n-butylphthalide on ischemic neurological damage and abnormal behavior in rats subjected to focal ischemia]. Yao Xue Xue Bao 1995; 30: 896-903
    • (1995) Yao Xue Xue Bao , vol.30 , pp. 896-903
    • Liu, X.G.1    Feng, Y.P.2
  • 17
    • 0346823803 scopus 로고
    • Effect of DL-butylphthalide (NBP) on mouse brain energy metabolism in complete brain ischemia induced by decapitation
    • Feng YP, Hu D, Zhang LY. [Effect of DL-butylphthalide (NBP) on mouse brain energy metabolism in complete brain ischemia induced by decapitation]. Yao Xue Xue Bao 1995; 30: 741-744
    • (1995) Yao Xue Xue Bao , vol.30 , pp. 741-744
    • Feng, Y.P.1    Hu, D.2    Zhang, L.Y.3
  • 18
    • 2942640550 scopus 로고    scopus 로고
    • Effects of NBP on ATPase and anti-oxidant enzymes activities and lipid peroxidation in transient focal cerebral ischemic rats
    • Dong GX, Feng YP. [Effects of NBP on ATPase and anti-oxidant enzymes activities and lipid peroxidation in transient focal cerebral ischemic rats]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2002; 24: 93-97
    • (2002) Zhongguo Yi Xue Ke Xue Yuan Xue Bao , vol.24 , pp. 93-97
    • Dong, G.X.1    Feng, Y.P.2
  • 19
    • 0034030503 scopus 로고    scopus 로고
    • Inhibitory effects of chiral 3-n-butylphthalide on inflammation following focal ischemic brain injury in rats
    • Xu HL, Feng YP. Inhibitory effects of chiral 3-n-butylphthalide on inflammation following focal ischemic brain injury in rats. Acta Pharmacol Sin 2000; 21: 433-438
    • (2000) Acta Pharmacol Sin , vol.21 , pp. 433-438
    • Xu, H.L.1    Feng, Y.P.2
  • 20
    • 0031021960 scopus 로고    scopus 로고
    • Reactive astrocytosis from excitotoxic injury in hippocampal organ culture parallels that seen in vivo
    • Kunkler PE, Kraig RP. Reactive astrocytosis from excitotoxic injury in hippocampal organ culture parallels that seen in vivo. J Cereb Blood Flow Metab 1997; 17: 26-43
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 26-43
    • Kunkler, P.E.1    Kraig, R.P.2
  • 21
    • 55049120934 scopus 로고    scopus 로고
    • Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase
    • Gowing G, Philips T, van Wijmeersch B, et al. Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. J Neurosci 2008; 28: 10234-10244
    • (2008) J Neurosci , vol.28 , pp. 10234-10244
    • Gowing, G.1    Philips, T.2    Van Wijmeersch, B.3
  • 22
    • 0029830517 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in pediatric and adult cerebral arteriovenous malformations: An immunocytochemical study
    • Sonstein WJ, Kader A, Michelsen WJ, et al. Expression of vascular endothelial growth factor in pediatric and adult cerebral arteriovenous malformations: an immunocytochemical study. J Neurosurg 1996; 85: 838-845
    • (1996) J Neurosurg , vol.85 , pp. 838-845
    • Sonstein, W.J.1    Kader, A.2    Michelsen, W.J.3
  • 23
    • 3343011970 scopus 로고    scopus 로고
    • Caspase activation, inhibition, and reactivation: A mechanistic view
    • Shi Y. Caspase activation, inhibition, and reactivation: A mechanistic view. Protein Sci 2004; 13: 1979-1987
    • (2004) Protein Sci , vol.13 , pp. 1979-1987
    • Shi, Y.1
  • 24
    • 0032782809 scopus 로고    scopus 로고
    • Inverse correlation between apoptotic (Fas ligand, caspase-3) and angiogenic factors (VEGF, microvessel density) in squamous cell lung carcinomas
    • Volm M, Mattern J, Koomagi R. Inverse correlation between apoptotic (Fas ligand, caspase-3) and angiogenic factors (VEGF, microvessel density) in squamous cell lung carcinomas. Anticancer Res 1999; 19: 1669-1671
    • (1999) Anticancer Res , vol.19 , pp. 1669-1671
    • Volm, M.1    Mattern, J.2    Koomagi, R.3
  • 25
    • 0023894768 scopus 로고
    • Neurobehavioral complications of type i diabetes. Examination of possible risk factors
    • Ryan CM. Neurobehavioral complications of type I diabetes. Examination of possible risk factors. Diabetes Care 1988; 11: 86-93
    • (1988) Diabetes Care , vol.11 , pp. 86-93
    • Ryan, C.M.1
  • 26
    • 0030961020 scopus 로고    scopus 로고
    • The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy
    • Low PA, Nickander KK, Tritschler HJ. The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy. Diabetes 1997; 46 (Suppl. 2): S38-S42
    • (1997) Diabetes , vol.46 , Issue.SUPPL. 2
    • Low, P.A.1    Nickander, K.K.2    Tritschler, H.J.3
  • 27
    • 12244299849 scopus 로고    scopus 로고
    • Increase of glial fibrillary acidic protein and S-100B in hippocampus and cortex of diabetic rats: Effects of vitamin e
    • Baydas G, Nedzvetskii V S, Tuzcu M, et al. Increase of glial fibrillary acidic protein and S-100B in hippocampus and cortex of diabetic rats: Effects of vitamin E. Eur J Pharmacol 2003; 462: 67-71
    • (2003) Eur J Pharmacol , vol.462 , pp. 67-71
    • Baydas, G.1    Nedzvetskii, V.S.2    Tuzcu, M.3
  • 28
    • 0030610936 scopus 로고    scopus 로고
    • Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells
    • Guastadisegni C, Minghetti L, Nicolini A, et al. Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells. FEBS Lett 1997; 413: 314-318
    • (1997) FEBS Lett , vol.413 , pp. 314-318
    • Guastadisegni, C.1    Minghetti, L.2    Nicolini, A.3
  • 29
    • 0028240615 scopus 로고
    • Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia
    • Endoh M, Maiese K, Wagner J. Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia. Brain Res 1994; 651: 92-100
    • (1994) Brain Res , vol.651 , pp. 92-100
    • Endoh, M.1    Maiese, K.2    Wagner, J.3
  • 30
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, et al. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992; 359: 843-845
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3
  • 31
    • 4644224534 scopus 로고    scopus 로고
    • The involvement of growth hormone (GH), insulin-like growth factors (IGFs) and vascular endothelial growth factor (VEGF) in diabetic kidney disease
    • Flyvbjerg A, Khatir DS, Jensen LJ, et al. The involvement of growth hormone (GH), insulin-like growth factors (IGFs) and vascular endothelial growth factor (VEGF) in diabetic kidney disease. Curr Pharm Des 2004; 10: 3385-3394
    • (2004) Curr Pharm des , vol.10 , pp. 3385-3394
    • Flyvbjerg, A.1    Khatir, D.S.2    Jensen, L.J.3
  • 32
    • 0033496252 scopus 로고    scopus 로고
    • Activated microvessels express vascular endothelial growth factor and integrin alpha(v)- beta3 during focal cerebral ischemia
    • Abumiya T, Lucero J, Heo JH, et al. Activated microvessels express vascular endothelial growth factor and integrin alpha(v)- beta3 during focal cerebral ischemia. J Cereb Blood Flow Metab 1999; 19: 1038-1050
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1038-1050
    • Abumiya, T.1    Lucero, J.2    Heo, J.H.3
  • 33
    • 0033574402 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor mRNA following transient forebrain ischemia in rats
    • Lee MY, Ju WK, Cha JH, et al. Expression of vascular endothelial growth factor mRNA following transient forebrain ischemia in rats. Neurosci Lett 1999; 265: 107-110
    • (1999) Neurosci Lett , vol.265 , pp. 107-110
    • Lee, M.Y.1    Ju, W.K.2    Cha, J.H.3
  • 34
    • 0032989129 scopus 로고    scopus 로고
    • Cell type specific upregulation of vascular endothelial growth factor in an MCA-occlusion model of cerebral infarct
    • Plate KH, Beck H, Danner S, et al. Cell type specific upregulation of vascular endothelial growth factor in an MCA-occlusion model of cerebral infarct. J Neuropathol Exp Neurol 1999; 58: 654-666
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 654-666
    • Plate, K.H.1    Beck, H.2    Danner, S.3
  • 35
  • 36
    • 0028870050 scopus 로고
    • Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
    • Shweiki D, Neeman M, Itin A, et al. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis. Proc Natl Acad Sci USA 1995; 92: 768-772
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 768-772
    • Shweiki, D.1    Neeman, M.2    Itin, A.3
  • 37
    • 0029926439 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is induced by long-term high glucose concentration and up-regulated by acute glucose deprivation in cultured bovine retinal pigmented epithelial cells
    • Sone H, Kawakami Y, Okuda Y, et al. Vascular endothelial growth factor is induced by long-term high glucose concentration and up-regulated by acute glucose deprivation in cultured bovine retinal pigmented epithelial cells. Biochem Biophys Res Commun 1996; 221: 193-198
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 193-198
    • Sone, H.1    Kawakami, Y.2    Okuda, Y.3
  • 38
    • 0030665927 scopus 로고    scopus 로고
    • Apoptosis: Clinical relevance and pharmacological manipulation
    • Thatte U, Dahanukar S. Apoptosis: Clinical relevance and pharmacological manipulation. Drugs 1997; 54: 511-532
    • (1997) Drugs , vol.54 , pp. 511-532
    • Thatte, U.1    Dahanukar, S.2
  • 39
    • 34249828655 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative disease
    • Burke RE. Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative disease. Pharmacol Ther 2007; 114: 261-277
    • (2007) Pharmacol Ther , vol.114 , pp. 261-277
    • Burke, R.E.1
  • 40
    • 0033848792 scopus 로고    scopus 로고
    • Vascular endothelial growth factor rescues HN33 neural cells from death induced by serum withdrawal
    • Jin KL, Mao XO, Greenberg DA. Vascular endothelial growth factor rescues HN33 neural cells from death induced by serum withdrawal. J Mol Neurosci 2000; 14: 197-203
    • (2000) J Mol Neurosci , vol.14 , pp. 197-203
    • Jin, K.L.1    Mao, X.O.2    Greenberg, D.A.3
  • 41
    • 0000481740 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia
    • Jin KL, Mao XO, Greenberg DA. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc Natl Acad Sci USA 2000; 97: 10242-11027
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10242-11027
    • Jin, K.L.1    Mao, X.O.2    Greenberg, D.A.3
  • 42
    • 0041733627 scopus 로고    scopus 로고
    • Effects of chiral 3-n-butylphthalide on apoptosis induced by transient focal cerebral ischemia in rats
    • Chang Q, Wang XL. Effects of chiral 3-n-butylphthalide on apoptosis induced by transient focal cerebral ischemia in rats. Acta Pharmacol Sin 2003; 24: 796-804
    • (2003) Acta Pharmacol Sin , vol.24 , pp. 796-804
    • Chang, Q.1    Wang, X.L.2
  • 43
    • 34248560915 scopus 로고    scopus 로고
    • L-3-n-Butylphthalide improves cognitive impairment induced by chronic cerebral hypoperfusion in rats
    • Peng Y, Xu S, Chen G, et al. l-3-n-Butylphthalide improves cognitive impairment induced by chronic cerebral hypoperfusion in rats. J Pharmacol Exp Ther 2007; 321: 902-910
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 902-910
    • Peng, Y.1    Xu, S.2    Chen, G.3
  • 44
    • 0034717542 scopus 로고    scopus 로고
    • Activity-dependent neuronal control of gap-junctional communication in astrocytes
    • Rouach N, Glowinski J, Giaume C. Activity-dependent neuronal control of gap-junctional communication in astrocytes. J Cell Biol 2000; 149: 1513-1526
    • (2000) J Cell Biol , vol.149 , pp. 1513-1526
    • Rouach, N.1    Glowinski, J.2    Giaume, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.