-
1
-
-
16444377660
-
Dependence of self-tolerance on TRAF6-directed development of thymic stroma
-
Akiyama T., Maeda S., Yamane S., Ogino K., Kasai M., Kajiura F., Matsumoto M., Inoue J. Dependence of self-tolerance on TRAF6-directed development of thymic stroma. Science 2005, 308:248-251.
-
(2005)
Science
, vol.308
, pp. 248-251
-
-
Akiyama, T.1
Maeda, S.2
Yamane, S.3
Ogino, K.4
Kasai, M.5
Kajiura, F.6
Matsumoto, M.7
Inoue, J.8
-
2
-
-
0027465451
-
MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus
-
Anderson G., Jenkinson E.J., Moore N.C., Owen J.J. MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus. Nature 1993, 362:70-73.
-
(1993)
Nature
, vol.362
, pp. 70-73
-
-
Anderson, G.1
Jenkinson, E.J.2
Moore, N.C.3
Owen, J.J.4
-
3
-
-
34248598295
-
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
-
Aschenbrenner K., D'Cruz L.M., Vollmann E.H., Hinterberger M., Emmerich J., Swee L.K., Rolink A., Klein L. Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. Nat. Immunol. 2007, 8:351-358.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 351-358
-
-
Aschenbrenner, K.1
D'Cruz, L.M.2
Vollmann, E.H.3
Hinterberger, M.4
Emmerich, J.5
Swee, L.K.6
Rolink, A.7
Klein, L.8
-
4
-
-
20844435029
-
Prevention of toxic epidermal necrolysis by regulatory T cells
-
Azukizawa H., Sano S., Kosaka H., Sumikawa Y., Itami S. Prevention of toxic epidermal necrolysis by regulatory T cells. Eur. J. Immunol. 2005, 35:1722-1730.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 1722-1730
-
-
Azukizawa, H.1
Sano, S.2
Kosaka, H.3
Sumikawa, Y.4
Itami, S.5
-
5
-
-
0036063262
-
Identification and characterization of thymic epithelial progenitor cells
-
Bennett A.R., Farley A., Blair N.F., Gordon J., Sharp L., Blackburn C.C. Identification and characterization of thymic epithelial progenitor cells. Immunity 2002, 16:803-814.
-
(2002)
Immunity
, vol.16
, pp. 803-814
-
-
Bennett, A.R.1
Farley, A.2
Blair, N.F.3
Gordon, J.4
Sharp, L.5
Blackburn, C.C.6
-
6
-
-
0024450056
-
Positive selection of the T cell repertoire: where and when does it occur?
-
Benoist C., Mathis D. Positive selection of the T cell repertoire: where and when does it occur?. Cell 1989, 58:1027-1033.
-
(1989)
Cell
, vol.58
, pp. 1027-1033
-
-
Benoist, C.1
Mathis, D.2
-
7
-
-
0024428184
-
Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand
-
Berg L.J., Pullen A.M., Fazekas de St Groth B., Mathis D., Benoist C., Davis M.M. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell 1989, 58:1035-1046.
-
(1989)
Cell
, vol.58
, pp. 1035-1046
-
-
Berg, L.J.1
Pullen, A.M.2
Fazekas de St Groth, B.3
Mathis, D.4
Benoist, C.5
Davis, M.M.6
-
8
-
-
26844543561
-
BMP signaling is required for normal thymus development
-
Bleul C.C., Boehm T. BMP signaling is required for normal thymus development. J. Immunol. 2005, 175:5213-5221.
-
(2005)
J. Immunol.
, vol.175
, pp. 5213-5221
-
-
Bleul, C.C.1
Boehm, T.2
-
9
-
-
33745532385
-
Formation of a functional thymus initiated by a postnatal epithelial progenitor cell
-
Bleul C.C., Corbeaux T., Reuter A., Fisch P., Monting J.S., Boehm T. Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. Nature 2006, 441:992-996.
-
(2006)
Nature
, vol.441
, pp. 992-996
-
-
Bleul, C.C.1
Corbeaux, T.2
Reuter, A.3
Fisch, P.4
Monting, J.S.5
Boehm, T.6
-
10
-
-
0346503889
-
Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice
-
Branda C.S., Dymecki S.M. Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev. Cell 2004, 6:7-28.
-
(2004)
Dev. Cell
, vol.6
, pp. 7-28
-
-
Branda, C.S.1
Dymecki, S.M.2
-
11
-
-
0035282767
-
Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells
-
Capone M., Romagnoli P., Beermann F., MacDonald H.R., van Meerwijk J.P. Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells. Blood 2001, 97:1336-1342.
-
(2001)
Blood
, vol.97
, pp. 1336-1342
-
-
Capone, M.1
Romagnoli, P.2
Beermann, F.3
MacDonald, H.R.4
van Meerwijk, J.P.5
-
12
-
-
0042941765
-
Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro
-
Chen Y., Stamatoyannopoulos G., Song C.Z. Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res. 2003, 63:4801-4804.
-
(2003)
Cancer Res.
, vol.63
, pp. 4801-4804
-
-
Chen, Y.1
Stamatoyannopoulos, G.2
Song, C.Z.3
-
13
-
-
77949312399
-
Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy
-
Cheng L., Guo J., Sun L., Fu J., Barnes P.F., Metzger D., Chambon P., Oshima R.G., Amagai T., Su D.M. Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy. J. Biol. Chem. 2010, 285:5836-5847.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 5836-5847
-
-
Cheng, L.1
Guo, J.2
Sun, L.3
Fu, J.4
Barnes, P.F.5
Metzger, D.6
Chambon, P.7
Oshima, R.G.8
Amagai, T.9
Su, D.M.10
-
14
-
-
0036592062
-
Expression, genomic structure and mapping of the thymus specific protease prss16: a candidate gene for insulin dependent diabetes mellitus susceptibility
-
Cheunsuk S., Sparks R., Noveroske J.K., Hsu T., Justice M.J., Gershwin M.E., Gruen J.R., Bowlus C.L. Expression, genomic structure and mapping of the thymus specific protease prss16: a candidate gene for insulin dependent diabetes mellitus susceptibility. J. Autoimmun. 2002, 18:311-316.
-
(2002)
J. Autoimmun.
, vol.18
, pp. 311-316
-
-
Cheunsuk, S.1
Sparks, R.2
Noveroske, J.K.3
Hsu, T.4
Justice, M.J.5
Gershwin, M.E.6
Gruen, J.R.7
Bowlus, C.L.8
-
15
-
-
0030908652
-
Long-lasting adenovirus transgene expression in mice through neonatal intrathymic tolerance induction without the use of immunosuppression
-
DeMatteo R.P., Chu G., Ahn M., Chang E., Barker C.F., Markmann J.F. Long-lasting adenovirus transgene expression in mice through neonatal intrathymic tolerance induction without the use of immunosuppression. J. Virol. 1997, 71:5330-5335.
-
(1997)
J. Virol.
, vol.71
, pp. 5330-5335
-
-
DeMatteo, R.P.1
Chu, G.2
Ahn, M.3
Chang, E.4
Barker, C.F.5
Markmann, J.F.6
-
16
-
-
0029154674
-
Gene transfer to the thymus. A means of abrogating the immune response to recombinant adenovirus
-
discussion 239-242
-
DeMatteo R.P., Raper S.E., Ahn M., Fisher K.J., Burke C., Radu A., Widera G., Claytor B.R., Barker C.F., Markmann J.F. Gene transfer to the thymus. A means of abrogating the immune response to recombinant adenovirus. Ann. Surg. 1995, 222:229-239. discussion 239-242.
-
(1995)
Ann. Surg.
, vol.222
, pp. 229-239
-
-
DeMatteo, R.P.1
Raper, S.E.2
Ahn, M.3
Fisher, K.J.4
Burke, C.5
Radu, A.6
Widera, G.7
Claytor, B.R.8
Barker, C.F.9
Markmann, J.F.10
-
17
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
Dickins R.A., Hemann M.T., Zilfou J.T., Simpson D.R., Ibarra I., Hannon G.J., Lowe S.W. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat. Genet. 2005, 37:1289-1295.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1289-1295
-
-
Dickins, R.A.1
Hemann, M.T.2
Zilfou, J.T.3
Simpson, D.R.4
Ibarra, I.5
Hannon, G.J.6
Lowe, S.W.7
-
18
-
-
70349194383
-
Thymus-specific deletion of insulin induces autoimmune diabetes
-
Fan Y., Rudert W.A., Grupillo M., He J., Sisino G., Trucco M. Thymus-specific deletion of insulin induces autoimmune diabetes. EMBO J. 2009, 28:2812-2824.
-
(2009)
EMBO J.
, vol.28
, pp. 2812-2824
-
-
Fan, Y.1
Rudert, W.A.2
Grupillo, M.3
He, J.4
Sisino, G.5
Trucco, M.6
-
19
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
20
-
-
49449093723
-
Deletional tolerance mediated by extrathymic Aire-expressing cells
-
Gardner J.M., Devoss J.J., Friedman R.S., Wong D.J., Tan Y.X., Zhou X., Johannes K.P., Su M.A., Chang H.Y., Krummel M.F., Anderson M.S. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science 2008, 321:843-847.
-
(2008)
Science
, vol.321
, pp. 843-847
-
-
Gardner, J.M.1
Devoss, J.J.2
Friedman, R.S.3
Wong, D.J.4
Tan, Y.X.5
Zhou, X.6
Johannes, K.P.7
Su, M.A.8
Chang, H.Y.9
Krummel, M.F.10
Anderson, M.S.11
-
21
-
-
0036305567
-
Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells
-
Gill J., Malin M., Hollander G.A., Boyd R. Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells. Nat. Immunol. 2002, 3:635-642.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 635-642
-
-
Gill, J.1
Malin, M.2
Hollander, G.A.3
Boyd, R.4
-
22
-
-
77649191415
-
Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis
-
Gordon J., Patel S.R., Mishina Y., Manley N.R. Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis. Dev. Biol. 2010, 339:141-154.
-
(2010)
Dev. Biol.
, vol.339
, pp. 141-154
-
-
Gordon, J.1
Patel, S.R.2
Mishina, Y.3
Manley, N.R.4
-
23
-
-
34447104270
-
Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus
-
Gordon J., Xiao S., Hughes B., Su D.M., Navarre S.P., Condie B.G., Manley N.R. Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus. BMC Dev. Biol. 2007, 7:69.
-
(2007)
BMC Dev. Biol.
, vol.7
, pp. 69
-
-
Gordon, J.1
Xiao, S.2
Hughes, B.3
Su, D.M.4
Navarre, S.P.5
Condie, B.G.6
Manley, N.R.7
-
24
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen M., Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. U.S.A. 1992, 89:5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
25
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm D., Streetz K.L., Jopling C.L., Storm T.A., Pandey K., Davis C.R., Marion P., Salazar F., Kay M.A. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 2006, 441:537-541.
-
(2006)
Nature
, vol.441
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.7
Salazar, F.8
Kay, M.A.9
-
26
-
-
77249138258
-
A review of current large-scale mouse knockout efforts
-
Guan C., Ye C., Yang X., Gao J. A review of current large-scale mouse knockout efforts. Genesis 2010, 48:73-85.
-
(2010)
Genesis
, vol.48
, pp. 73-85
-
-
Guan, C.1
Ye, C.2
Yang, X.3
Gao, J.4
-
27
-
-
50949123978
-
TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution
-
Hauri-Hohl M.M., Zuklys S., Keller M.P., Jeker L.T., Barthlott T., Moon A.M., Roes J., Hollander G.A. TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution. Blood 2008, 112:626-634.
-
(2008)
Blood
, vol.112
, pp. 626-634
-
-
Hauri-Hohl, M.M.1
Zuklys, S.2
Keller, M.P.3
Jeker, L.T.4
Barthlott, T.5
Moon, A.M.6
Roes, J.7
Hollander, G.A.8
-
28
-
-
77952568022
-
Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance
-
Hinterberger M., Aichinger M., da Costa O.P., Voehringer D., Hoffmann R., Klein L. Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance. Nat. Immunol. 2010, 11:512-519.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 512-519
-
-
Hinterberger, M.1
Aichinger, M.2
da Costa, O.P.3
Voehringer, D.4
Hoffmann, R.5
Klein, L.6
-
29
-
-
58149154746
-
Delta-like 4 is indispensable in thymic environment specific for T cell development
-
Hozumi K., Mailhos C., Negishi N., Hirano K., Yahata T., Ando K., Zuklys S., Hollander G.A., Shima D.T., Habu S. Delta-like 4 is indispensable in thymic environment specific for T cell development. J. Exp. Med. 2008, 205:2507-2513.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2507-2513
-
-
Hozumi, K.1
Mailhos, C.2
Negishi, N.3
Hirano, K.4
Yahata, T.5
Ando, K.6
Zuklys, S.7
Hollander, G.A.8
Shima, D.T.9
Habu, S.10
-
30
-
-
0029849639
-
Induction of central tolerance by intrathymic inoculation of adenoviral antigens into the host thymus permits long-term gene therapy in Gunn rats
-
Ilan Y., Attavar P., Takahashi M., Davidson A., Horwitz M.S., Guida J., Chowdhury N.R., Chowdhury J.R. Induction of central tolerance by intrathymic inoculation of adenoviral antigens into the host thymus permits long-term gene therapy in Gunn rats. J. Clin. Invest. 1996, 98:2640-2647.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 2640-2647
-
-
Ilan, Y.1
Attavar, P.2
Takahashi, M.3
Davidson, A.4
Horwitz, M.S.5
Guida, J.6
Chowdhury, N.R.7
Chowdhury, J.R.8
-
31
-
-
0033571243
-
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases
-
Indra A.K., Warot X., Brocard J., Bornert J.M., Xiao J.H., Chambon P., Metzger D. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res. 1999, 27:4324-4327.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 4324-4327
-
-
Indra, A.K.1
Warot, X.2
Brocard, J.3
Bornert, J.M.4
Xiao, J.H.5
Chambon, P.6
Metzger, D.7
-
32
-
-
51349101423
-
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity
-
Irla M., Hugues S., Gill J., Nitta T., Hikosaka Y., Williams I.R., Hubert F.X., Scott H.S., Takahama Y., Hollander G.A., Reith W. Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity. Immunity 2008, 29:451-463.
-
(2008)
Immunity
, vol.29
, pp. 451-463
-
-
Irla, M.1
Hugues, S.2
Gill, J.3
Nitta, T.4
Hikosaka, Y.5
Williams, I.R.6
Hubert, F.X.7
Scott, H.S.8
Takahama, Y.9
Hollander, G.A.10
Reith, W.11
-
33
-
-
55749107446
-
Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells
-
Jeker L.T., Barthlott T., Keller M.P., Zuklys S., Hauri-Hohl M., Deng C.X., Hollander G.A. Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells. Blood 2008, 112:3688-3695.
-
(2008)
Blood
, vol.112
, pp. 3688-3695
-
-
Jeker, L.T.1
Barthlott, T.2
Keller, M.P.3
Zuklys, S.4
Hauri-Hohl, M.5
Deng, C.X.6
Hollander, G.A.7
-
34
-
-
2342627912
-
Control of siRNA expression using the Cre-loxP recombination system
-
Kasim V., Miyagishi M., Taira K. Control of siRNA expression using the Cre-loxP recombination system. Nucleic Acids Res. 2004, 32:e66.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Kasim, V.1
Miyagishi, M.2
Taira, K.3
-
35
-
-
72949104779
-
Antigen presentation in the thymus for positive selection and central tolerance induction
-
Klein L., Hinterberger M., Wirnsberger G., Kyewski B. Antigen presentation in the thymus for positive selection and central tolerance induction. Nat. Rev. Immunol. 2009, 9:833-844.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 833-844
-
-
Klein, L.1
Hinterberger, M.2
Wirnsberger, G.3
Kyewski, B.4
-
36
-
-
79251595980
-
Conditional RNAi in mice
-
Kleinhammer A., Deussing J., Wurst W., Kuehn R. Conditional RNAi in mice. Methods 2011, 53:142-150.
-
(2011)
Methods
, vol.53
, pp. 142-150
-
-
Kleinhammer, A.1
Deussing, J.2
Wurst, W.3
Kuehn, R.4
-
37
-
-
0037105620
-
Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus
-
Klug D.B., Carter C., Gimenez-Conti I.B., Richie E.R. Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus. J. Immunol. 2002, 169:2842-2845.
-
(2002)
J. Immunol.
, vol.169
, pp. 2842-2845
-
-
Klug, D.B.1
Carter, C.2
Gimenez-Conti, I.B.3
Richie, E.R.4
-
38
-
-
0038708339
-
Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype
-
Kunath T., Gish G., Lickert H., Jones N., Pawson T., Rossant J. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat. Biotechnol. 2003, 21:559-561.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 559-561
-
-
Kunath, T.1
Gish, G.2
Lickert, H.3
Jones, N.4
Pawson, T.5
Rossant, J.6
-
39
-
-
33646165128
-
A central role for central tolerance
-
Kyewski B., Klein L. A central role for central tolerance. Annu. Rev. Immunol. 2006, 24:571-606.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 571-606
-
-
Kyewski, B.1
Klein, L.2
-
40
-
-
0029835390
-
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
-
Laufer T.M., DeKoning J., Markowitz J.S., Lo D., Glimcher L.H. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 1996, 383:81-85.
-
(1996)
Nature
, vol.383
, pp. 81-85
-
-
Laufer, T.M.1
DeKoning, J.2
Markowitz, J.S.3
Lo, D.4
Glimcher, L.H.5
-
42
-
-
33846237346
-
Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells
-
Lomada D., Liu B., Coghlan L., Hu Y., Richie E.R. Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells. J. Immunol. 2007, 178:829-837.
-
(2007)
J. Immunol.
, vol.178
, pp. 829-837
-
-
Lomada, D.1
Liu, B.2
Coghlan, L.3
Hu, Y.4
Richie, E.R.5
-
43
-
-
33751177983
-
Induction of antigen-specific tolerance by intrathymic injection of lentiviral vectors
-
Marodon G., Fisson S., Levacher B., Fabre M., Salomon B.L., Klatzmann D. Induction of antigen-specific tolerance by intrathymic injection of lentiviral vectors. Blood 2006, 108:2972-2978.
-
(2006)
Blood
, vol.108
, pp. 2972-2978
-
-
Marodon, G.1
Fisson, S.2
Levacher, B.3
Fabre, M.4
Salomon, B.L.5
Klatzmann, D.6
-
44
-
-
26444493207
-
In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors
-
Marodon G., Klatzmann D. In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors. BMC Immunol. 2004, 5:18.
-
(2004)
BMC Immunol.
, vol.5
, pp. 18
-
-
Marodon, G.1
Klatzmann, D.2
-
45
-
-
0041940113
-
Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis
-
Matsumoto T., Jiang J., Kiguchi K., Ruffino L., Carbajal S., Beltran L., Bol D.K., Rosenberg M.P., DiGiovanni J. Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis. Cancer Res. 2003, 63:4819-4828.
-
(2003)
Cancer Res.
, vol.63
, pp. 4819-4828
-
-
Matsumoto, T.1
Jiang, J.2
Kiguchi, K.3
Ruffino, L.4
Carbajal, S.5
Beltran, L.6
Bol, D.K.7
Rosenberg, M.P.8
DiGiovanni, J.9
-
47
-
-
0029164598
-
Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase
-
Metzger D., Clifford J., Chiba H., Chambon P. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:6991-6995.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 6991-6995
-
-
Metzger, D.1
Clifford, J.2
Chiba, H.3
Chambon, P.4
-
48
-
-
29244472802
-
Vestigial no more
-
Miller J.F. Vestigial no more. Nat. Immunol. 2006, 7:3-5.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 3-5
-
-
Miller, J.F.1
-
49
-
-
61649110445
-
Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates
-
Moreau A., Vicente R., Dubreil L., Adjali O., Podevin G., Jacquet C., Deschamps J.Y., Klatzmann D., Cherel Y., Taylor N., et al. Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates. Mol. Ther. 2009, 17:472-479.
-
(2009)
Mol. Ther.
, vol.17
, pp. 472-479
-
-
Moreau, A.1
Vicente, R.2
Dubreil, L.3
Adjali, O.4
Podevin, G.5
Jacquet, C.6
Deschamps, J.Y.7
Klatzmann, D.8
Cherel, Y.9
Taylor, N.10
-
50
-
-
34249883977
-
Regulation of CD8+ T cell development by thymus-specific proteasomes
-
Murata S., Sasaki K., Kishimoto T., Niwa S., Hayashi H., Takahama Y., Tanaka K. Regulation of CD8+ T cell development by thymus-specific proteasomes. Science 2007, 316:1349-1353.
-
(2007)
Science
, vol.316
, pp. 1349-1353
-
-
Murata, S.1
Sasaki, K.2
Kishimoto, T.3
Niwa, S.4
Hayashi, H.5
Takahama, Y.6
Tanaka, K.7
-
51
-
-
0031056062
-
Positive selection of T cells induced by viral delivery of neopeptides to the thymus
-
Nakano N., Rooke R., Benoist C., Mathis D. Positive selection of T cells induced by viral delivery of neopeptides to the thymus. Science 1997, 275:678-683.
-
(1997)
Science
, vol.275
, pp. 678-683
-
-
Nakano, N.1
Rooke, R.2
Benoist, C.3
Mathis, D.4
-
52
-
-
52149099867
-
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
-
Nedjic J., Aichinger M., Emmerich J., Mizushima N., Klein L. Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 2008, 455:396-400.
-
(2008)
Nature
, vol.455
, pp. 396-400
-
-
Nedjic, J.1
Aichinger, M.2
Emmerich, J.3
Mizushima, N.4
Klein, L.5
-
53
-
-
64049084637
-
Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules
-
Nedjic J., Aichinger M., Mizushima N., Klein L. Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules. Curr. Opin. Immunol. 2009, 21:92-97.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 92-97
-
-
Nedjic, J.1
Aichinger, M.2
Mizushima, N.3
Klein, L.4
-
54
-
-
77952302980
-
Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation
-
Nishikawa Y., Hirota F., Yano M., Kitajima H., Miyazaki J., Kawamoto H., Mouri Y., Matsumoto M. Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation. J. Exp. Med. 2010, 207:963-971.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 963-971
-
-
Nishikawa, Y.1
Hirota, F.2
Yano, M.3
Kitajima, H.4
Miyazaki, J.5
Kawamoto, H.6
Mouri, Y.7
Matsumoto, M.8
-
55
-
-
0021257136
-
Successful transplantation across major histocompatibility barrier of deoxyguanosine-treated embryonic thymus expressing class II antigens
-
Ready A.R., Jenkinson E.J., Kingston R., Owen J.J. Successful transplantation across major histocompatibility barrier of deoxyguanosine-treated embryonic thymus expressing class II antigens. Nature 1984, 310:231-233.
-
(1984)
Nature
, vol.310
, pp. 231-233
-
-
Ready, A.R.1
Jenkinson, E.J.2
Kingston, R.3
Owen, J.J.4
-
56
-
-
38449091619
-
Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection
-
Ribot J., Enault G., Pilipenko S., Huchenq A., Calise M., Hudrisier D., Romagnoli P., van Meerwijk J.P. Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection. J. Immunol. 2007, 179:6741-6748.
-
(2007)
J. Immunol.
, vol.179
, pp. 6741-6748
-
-
Ribot, J.1
Enault, G.2
Pilipenko, S.3
Huchenq, A.4
Calise, M.5
Hudrisier, D.6
Romagnoli, P.7
van Meerwijk, J.P.8
-
57
-
-
0035856960
-
Thymus medulla consisting of epithelial islets each derived from a single progenitor
-
Rodewald H.R., Paul S., Haller C., Bluethmann H., Blum C. Thymus medulla consisting of epithelial islets each derived from a single progenitor. Nature 2001, 414:763-768.
-
(2001)
Nature
, vol.414
, pp. 763-768
-
-
Rodewald, H.R.1
Paul, S.2
Haller, C.3
Bluethmann, H.4
Blum, C.5
-
58
-
-
0030849637
-
Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses
-
Rooke R., Waltzinger C., Benoist C., Mathis D. Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses. Immunity 1997, 7:123-134.
-
(1997)
Immunity
, vol.7
, pp. 123-134
-
-
Rooke, R.1
Waltzinger, C.2
Benoist, C.3
Mathis, D.4
-
59
-
-
0032858292
-
Positive selection of thymocytes induced by gene transfer: MHC class II-mediated selection of CD8 lineage cells
-
Rooke R., Waltzinger C., Benoist C., Mathis D. Positive selection of thymocytes induced by gene transfer: MHC class II-mediated selection of CD8 lineage cells. Int. Immunol. 1999, 11:1595-1600.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1595-1600
-
-
Rooke, R.1
Waltzinger, C.2
Benoist, C.3
Mathis, D.4
-
60
-
-
0033643899
-
Intrathymic delivery of MHC genes using recombinant adenoviruses
-
Rooke R., Benoist C., Mathis D. Intrathymic delivery of MHC genes using recombinant adenoviruses. Methods Mol. Biol. 2000, 134:69-79.
-
(2000)
Methods Mol. Biol.
, vol.134
, pp. 69-79
-
-
Rooke, R.1
Benoist, C.2
Mathis, D.3
-
61
-
-
33745516115
-
Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium
-
Rossi S.W., Jenkinson W.E., Anderson G., Jenkinson E.J. Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature 2006, 441:988-991.
-
(2006)
Nature
, vol.441
, pp. 988-991
-
-
Rossi, S.W.1
Jenkinson, W.E.2
Anderson, G.3
Jenkinson, E.J.4
-
62
-
-
34250336454
-
RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
-
Rossi S.W., Kim M.Y., Leibbrandt A., Parnell S.M., Jenkinson W.E., Glanville S.H., McConnell F.M., Scott H.S., Penninger J.M., Jenkinson E.J., et al. RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J. Exp. Med. 2007, 204:1267-1272.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1267-1272
-
-
Rossi, S.W.1
Kim, M.Y.2
Leibbrandt, A.3
Parnell, S.M.4
Jenkinson, W.E.5
Glanville, S.H.6
McConnell, F.M.7
Scott, H.S.8
Penninger, J.M.9
Jenkinson, E.J.10
-
63
-
-
0034868746
-
Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival
-
Sano S., Takahama Y., Sugawara T., Kosaka H., Itami S., Yoshikawa K., Miyazaki J., van Ewijk W., Takeda J. Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival. Immunity 2001, 15:261-273.
-
(2001)
Immunity
, vol.15
, pp. 261-273
-
-
Sano, S.1
Takahama, Y.2
Sugawara, T.3
Kosaka, H.4
Itami, S.5
Yoshikawa, K.6
Miyazaki, J.7
van Ewijk, W.8
Takeda, J.9
-
65
-
-
77955379515
-
The power of reversibility regulating gene activities via tetracycline-controlled transcription
-
Schonig K., Bujard H., Gossen M. The power of reversibility regulating gene activities via tetracycline-controlled transcription. Methods Enzymol. 2010, 477:429-453.
-
(2010)
Methods Enzymol.
, vol.477
, pp. 429-453
-
-
Schonig, K.1
Bujard, H.2
Gossen, M.3
-
66
-
-
54049118794
-
Maintenance of thymic epithelial phenotype requires extrinsic signals in mouse and zebrafish
-
Soza-Ried C., Bleul C.C., Schorpp M., Boehm T. Maintenance of thymic epithelial phenotype requires extrinsic signals in mouse and zebrafish. J. Immunol. 2008, 181:5272-5277.
-
(2008)
J. Immunol.
, vol.181
, pp. 5272-5277
-
-
Soza-Ried, C.1
Bleul, C.C.2
Schorpp, M.3
Boehm, T.4
-
67
-
-
24944560377
-
A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
-
Stegmeier F., Hu G., Rickles R.J., Hannon G.J., Elledge S.J. A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:13212-13217.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 13212-13217
-
-
Stegmeier, F.1
Hu, G.2
Rickles, R.J.3
Hannon, G.J.4
Elledge, S.J.5
-
68
-
-
2442584612
-
CRE recombinase-inducible RNA interference mediated by lentiviral vectors
-
Tiscornia G., Tergaonkar V., Galimi F., Verma I.M. CRE recombinase-inducible RNA interference mediated by lentiviral vectors. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:7347-7351.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 7347-7351
-
-
Tiscornia, G.1
Tergaonkar, V.2
Galimi, F.3
Verma, I.M.4
-
69
-
-
0024279866
-
Compartmentalization of MHC class II gene expression in transgenic mice
-
van Ewijk W., Ron Y., Monaco J., Kappler J., Marrack P., Le Meur M., Gerlinger P., Durand B., Benoist C., Mathis D. Compartmentalization of MHC class II gene expression in transgenic mice. Cell 1988, 53:357-370.
-
(1988)
Cell
, vol.53
, pp. 357-370
-
-
van Ewijk, W.1
Ron, Y.2
Monaco, J.3
Kappler, J.4
Marrack, P.5
Le Meur, M.6
Gerlinger, P.7
Durand, B.8
Benoist, C.9
Mathis, D.10
-
70
-
-
9244244736
-
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells
-
van Santen H.M., Benoist C., Mathis D. Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. J. Exp. Med. 2004, 200:1221-1230.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1221-1230
-
-
van Santen, H.M.1
Benoist, C.2
Mathis, D.3
-
71
-
-
0000425845
-
Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice
-
Vassar R., Rosenberg M., Ross S., Tyner A., Fuchs E. Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc. Natl. Acad. Sci. U.S.A. 1989, 86:1563-1567.
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 1563-1567
-
-
Vassar, R.1
Rosenberg, M.2
Ross, S.3
Tyner, A.4
Fuchs, E.5
-
72
-
-
0037296091
-
Expression of conditional cre recombinase in epithelial tissues of transgenic mice
-
Wen F., Cecena G., Munoz-Ritchie V., Fuchs E., Chambon P., Oshima R.G. Expression of conditional cre recombinase in epithelial tissues of transgenic mice. Genesis 2003, 35:100-106.
-
(2003)
Genesis
, vol.35
, pp. 100-106
-
-
Wen, F.1
Cecena, G.2
Munoz-Ritchie, V.3
Fuchs, E.4
Chambon, P.5
Oshima, R.G.6
-
74
-
-
0034677036
-
Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules
-
Witherden D., van Oers N., Waltzinger C., Weiss A., Benoist C., Mathis D. Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules. J. Exp. Med. 2000, 191:355-364.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 355-364
-
-
Witherden, D.1
van Oers, N.2
Waltzinger, C.3
Weiss, A.4
Benoist, C.5
Mathis, D.6
-
75
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng Y., Wagner E.J., Cullen B.R. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 2002, 9:1327-1333.
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
76
-
-
64849101655
-
Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function
-
Zuklys S., Gill J., Keller M.P., Hauri-Hohl M., Zhanybekova S., Balciunaite G., Na K.J., Jeker L.T., Hafen K., Tsukamoto N., et al. Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J. Immunol. 2009, 182:2997-3007.
-
(2009)
J. Immunol.
, vol.182
, pp. 2997-3007
-
-
Zuklys, S.1
Gill, J.2
Keller, M.P.3
Hauri-Hohl, M.4
Zhanybekova, S.5
Balciunaite, G.6
Na, K.J.7
Jeker, L.T.8
Hafen, K.9
Tsukamoto, N.10
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