Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells

Oncogene

Volumn 31, Issue 2, 2012, Pages 187-199

  Wang, X ^a   Venugopal, C ^a   Manoranjan, B ^a   McFarlane, N ^a   O'Farrell, E ^a   Nolte, S ^a   Gunnarsson, T ^b   Hollenberg, R ^b   Kwiecien, J ^b   Northcott, P ^c   Taylor, M D ^c   Hawkins, C ^d   Singh, S K ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Bmi1; brain tumor initiating cells; CD133; chromatin immunoprecipitation; medulloblastoma; sonic hedgehog

Indexed keywords

BMI1 PROTEIN; CYCLOPAMINE; SONIC HEDGEHOG PROTEIN;

ADOLESCENT; ARTICLE; CHILD; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEEDBACK SYSTEM; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MEDULLOBLASTOMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN FUNCTION;

BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE KNOCKDOWN TECHNIQUES; HEDGEHOG PROTEINS; HUMANS; MEDULLOBLASTOMA; NUCLEAR PROTEINS; POLYCOMB REPRESSIVE COMPLEX 1; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS;

ERINACEIDAE;

EID: 84855804948     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.232     Document Type: Article

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