Manipulation of enzyme properties by noncanonical amino acid incorporation

Biotechnology Journal

Volumn 7, Issue 1, 2012, Pages 47-60

  Zheng, Shun ^a   Kwon, Inchan ^a  

^a University of Virginia   (United States)

Author keywords

Biocatalysis; Enzyme; Noncanonical amino acid; Protein engineering

Indexed keywords

AMINO ACID INCORPORATION; BIOCATALYSIS; CATALYTIC TURNOVER; DIRECTED EVOLUTION; FLUORESCENT PROTEIN; FUTURE DIRECTIONS; IN-VIVO; INTRINSIC FUNCTIONS; NATURAL AMINO ACIDS; PROTEIN DESIGN; PROTEIN ENGINEERING; RECENT PROGRESS; SITE-SPECIFIC; SOLVENT RESISTANCE; STABILITY LOSS; STRUCTURAL PERTURBATION; SUBSTRATE BINDING; SUBSTRATE SPECIFICITY; WILD-TYPE ENZYMES;

AMINO ACIDS; BINDING ENERGY; ENZYMES; GENETIC ENGINEERING; PROTEINS;

BIOCHEMICAL ENGINEERING;

HISTIDINE; LEUCINE; METHIONINE; PHENYLALANINE; PROLINE; TRYPTOPHAN; TYROSINE;

ANALYTIC METHOD; BINDING AFFINITY; CATALYSIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; NONCANONICAL AMINO ACID INCORPORATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; REVIEW;

AMINO ACIDS; ANIMALS; ENZYME STABILITY; ENZYMES; HUMANS; PROTEIN ENGINEERING; SUBSTRATE SPECIFICITY;

EID: 84855607689     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201100267     Document Type: Review

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