Enzymes harboring unnatural amino acids: Mechanistic and structural analysis of the enhanced catalytic activity of a glutathione transferase containing 5-flourotryptophan

Biochemistry

Volumn 37, Issue 18, 1998, Pages 6286-6294

  Parsons, James F ^a   Xiao, Gaoyi ^b   Gilliland, Gary L ^b   Armstrong, Richard N ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE;

AMINO ACID COMPOSITION; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HYDROGEN BONDING; ISOENZYMES; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RATS; TRYPTOPHAN;

FELIS CATUS;

EID: 0032485881     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980219e     Document Type: Article

References (34)

1. Hull, W. E., and Sykes, B. D. (1974) Biochemistry 13, 3431-3437.
2. Sykes, B. D., Weingarten, H. L., and Schlesinger, M. J. (1974) Proc. Natl. Acad. Sci. U.S.A. 71, 469-473.
3. Lu, P., Jarema, M., Mosser, K., and Daniel, W. E., Jr. (1976) Proc. Natl. Acad. Sci. U.S.A. 78, 3471-3475.
4. Kimber, B. J., Griffiths, D. V., Birdsall, B., King, R. W., Scudder, P., Freeney, J., Roberts, G. C. K., and Burgen, A. S. V. (1977) Biochemistry 16, 3492-3500.
5. Rule, G. S., Pratt, E. A., Simplaceanu, V., and Ho, C. (1987) Biochemistry 26, 549-556.
6. Peersen, O. B., Pratt, E. A., Truong, H.-T. N., Ho, C., and Rule, G. S. (1990) Biochemistry 29, 3256-3262.
7. Lui, S. M., and Cowan, J. A. (1994) J. Am. Chem. Soc. 116, 4483-4484.
8. Hoeltzli, S. D., and Frieden, C. (1996) Biochemistry 35, 16843-168451.
9. Duewel, H., Daub, E., Robison, V., and Honek, J. F. (1997) Biochemistry 36, 3404-3416.
10. Hoeltzli, S. D., and Frieden, C. (1998) Biochemistry 36, 387-398.
11. Hendrickson, W. A., Horton, J. R., and LeMaster, D. M. (1990) EMBO J. 9, 1665-1672.
12. Yagil, G. (1967) Tetrahedron 23, 2855-2861.
13. Armstrong, R. N. (1997) Chem. Res. Toxicol. 10, 2-18.
14. Ji, X., Zhang, P., Armstrong, R. N., and Gilliland, G. L. (1992) Biochemistry 31, 10169-10184.
15. Liu, S., Zhang, P., Ji, X., Johnson, W. W., Gilliland, G. L., and Armstrong, R. N. (1992) J. Biol. Chem. 267, 4296-4299.
16. Parsons, J. F., and Armstrong, R. N. (1996) J. Am. Chem. Soc. 118, 2295-2296.
17. Xiao, G., Parsons, J. F., Armstrong, R. N., and Gilliland, G. L. (1997) J. Am. Chem. Soc. 119, 9325-9326.
18. Leatherbarrow, R. J. (1992) Grafit Version 3.0, Erithacus Software Ltd., Staines, U.K.
19. Cleland, W. W. (1979) Methods Enzymol. 63, 103-138.
20. Johnson, W. W., Liu, S., Ji, X., Gilliland, G. L., and Armstrong, R. N. (1993) J. Biol. Chem. 268, 11508-11511.
21. Otwinowski, Z., and Minor, W. (1996) Methods Enzymol. 276, 307-326.
22. Brunger, A. T., (1992) X-PLOR version 3.1 - A system for X-ray crystallography and NMR, Yale University Press, New Haven, CT.
23. Tronrud, D. E. (1994) The TNT Refinement Package, Oregon State Board of Higher Education, Eugene, OR.
24. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A47, 110-119.
25. Laskowski, R. A., MacAurther, M. W., Moss, D. S., and Thornton, J. M., (1993) J. Appl. Crystallogr. 26, 283-291.
26. Jakobson, I., Warholm, M., and Mannervik, B. (1979) J. Biol. Chem. 254, 7085-7089.
27. Graminski, G. F., Kubo, Y., and Armstrong, R. N. (1989) Biochemistry 28, 3562-3568.
28. Ji, X., Johnson, W. W., Sesay, M. A., Dickert, L., Prasad, S. M., Ammon, H. L., Armstrong, R. N., and Gilliland, G. L. (1994) Biochemistry 33, 1043-1052.
29. Shan, S., and Armstrong, R. N. (1994) J. Biol. Chem. 269, 32373-32379.
30. Liu, S., Ji, X., Gilliland, G. L., Stevens, W. J., and Armstrong, R. N. (1993) J. Am. Chem. Soc. 115, 7910-7911.
31. Xiao, G., Liu, S., Ji, X., Johnson, W. W., Chen, J., Parsons, J. F., Stevens, W. J., Gilliland, G. L., and Armstrong, R. N. (1996) Biochemistry 35, 4753-4765.
32. Bender, M. L. (1971) Mechanisms of Homogeneous Catalysis from Protons to Proteins, p 23, John Wiley, New York.
33. Chen, W.-J., Boehlert, C. C., Rider, K., and Armstrong, R. N. (1985) Biochem. Biophys. Res. Commun. 128, 233-240.
34. Johnson, K. A. (1992) Enzymes 20, 1-61.