Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 27, 2006, Pages 10180-10185

  Link, A James ^a   Vink, Mandy K S ^a   Agard, Nicholas J ^b,c   Prescher, Jennifer A ^b,c   Bertozzi, Carolyn R ^b,c   Tirrell, David A ^a  

^a California Institute of Technology   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Azide alkyne ligation; Azidohomoalanine; Azidonorleucine; Click chemistry

Indexed keywords

AMINO ACID; AMINO ACID TRANSFER RNA LIGASE; AZIDE; AZIDONORLEUCINE; CELL SURFACE PROTEIN; GLYCINE; LEUCINE; METHIONINE TRANSFER RNA LIGASE; MUTANT PROTEIN; NORLEUCINE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL MUTATION; CELL SURFACE; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; FUNCTION TEST; GENE EXPRESSION SYSTEM; INDUCED MUTATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN SYNTHESIS; PROTEIN VARIANT; SCREENING;

AMINO ACIDS; AMINO ACYL-TRNA SYNTHETASES; BINDING SITES; BIOTIN; CATALYSIS; COPPER; ESCHERICHIA COLI; KINETICS; MOLECULAR STRUCTURE; MUTATION; PEPTIDE LIBRARY; RECOMBINANT PROTEINS;

ESCHERICHIA COLI;

EID: 33745892390     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0601167103     Document Type: Article

References (32)

1. Budisa, N. (2004) Angew. Chem. Int. Ed. 43, 6426-6463.
2. Link, A. J., Mock, M. L. & Tirrell, D. A. (2003) Curr. Opin. Biotechnol. 14, 603-609.
3. Kiick, K. L., van Hest, J. C. M. & Tirrell, D. A. (2000) Angew. Chem. Int. Ed. 39, 2148-2152.
4. Kiick, K. L., Weberskirch, R. & Tirrell, D. A. (2001) FEBS Lett. 502, 25-30.
5. Tang, Y. & Tirrell, D. A. (2001) J. Am. Chem. Soc. 123, 11089-11090.
6. Wang, P., Fichera, A., Kumar, K. & Tirrell, D. A. (2004) Angew. Chem. Int. Ed. 43, 3664-3656.
7. Ibba, M. & Hennecke, H. (1995) FEBS Lett. 364, 272-275.
8. Sharma, N., Furter, R., Kast, P. & Tirrell, D. A. (2000) FEBS Lett. 467, 37-40.
9. Bentin, T., Hamzavi, R., Salomonsson, J., Roy, H., Ibba, M. & Nielsen, P. E. (2004) J. Biol. Chem. 279, 19839-19845.
10. Kirshenbaum, K., Carrico, I. S. & Tirrell, D. A. (2002) Chembiochem 3, 235-237.
11. Datta, D., Wang, P., Carrico, I. S., Mayo, S. L. & Tirrell, D. A. (2002) J. Am. Chem. Soc. 124, 5652-5653.
12. Kim, W. Y., George, A., Evans, M. & Conticello, V. P. (2004) Chembiochem 5, 928-936.
13. Tang, Y. & Tirrell, D. A. (2002) Biochemistry 41, 10635-10645.
14. Doring, V., Mootz, H. D., Nangle, L. A., Hendrickson, T. L., de Crecy-Lagard, V., Schimmel, P. & Marliere, P. (2001) Science 292, 501-504.
15. Wang, L., Brock, A., Herberich, B. & Schultz, P. G. (2001) Science 292, 498-500.
16. Wang, L. & Schultz, P. G. (2005) Angew. Chem. Int. Ed. 44, 34-66.
17. Link, A. J. & Tirrell, D. A. (2003) J. Am. Chem. Soc. 125, 11164-11165.
18. Link, A. J., Vink, M. K. S. & Tirrell, D. A. (2004) J. Am. Chem. Soc. 126, 10598-10602.
19. Wang, Q., Chan, T. R., Hilgraf, R., Fokin, V. V., Sharpless, K. B. & Finn, M. G. (2003) J. Am. Chem. Soc. 125, 3192-3193.
20. Mechulam, Y., Schmitt, E., Maveyraud, L., Zelwer, C., Nureki, O., Yokoyama, S., Konno, M. & Blanquet, S. (1999) J. Mol. Biol. 294, 1287-1297.
21. Serre, L., Verdon, G., Choinowski, T., Hervouet, N., Risler, J. L. & Zelwer, C. (2001) J. Mol. Biol. 306, 863-876.
22. Crepin, T., Schmitt, E., Mechulam, Y., Sampson, P. B., Vaughan, M. D., Honek, J. F. & Blanquet, S. (2003) J. Mol. Biol. 332, 59-72.
23. Fersht, A. R. & Kaethner, M. M. (1976) Biochemistry 15, 3342-3346.
24. Fersht, A. R. (1977) Biochemistry 16, 1025-1030.
25. Englisch, S., Englisch, U., Vonderhaar, F. & Cramer, F. (1986) Nucleic Acids Res. 14, 7529-7539.
26. Harvey, B. R., Georgiou, G., Hayhurst, A., Jeong, K. J., Iverson, B. L. & Rogers, G. K. (2004) Proc. Natl. Acad. Sci. USA 101, 9193-9198.
27. Kiick, K. L. & Tirrell, D. A. (2000) Tetrahedron 56, 9487-9493.
28. Kiick, K. L., Saxon, E., Tirrell, D. A. & Bertozzi, C. R. (2002) Proc. Natl. Acad. Sci. USA 99, 19-24.
29. Mangold, J. B., Mischke, M. R. & Lavelle, J. M. (1989) Mutat. Res. 216, 27-33.
30. Agard, N. J., Prescher, J. A. & Bertozzi, C. R. (2004) J. Am. Chem. Soc. 126, 15046-15047.
31. Chan, T. R., Hilgraf, R., Sharpless, K. B. & Fokin, V. V. (2004) Org. Lett. 6, 2853-2855.
32. Hendrickson, T. L., Nomanhhoy, T. K. & Schimmel, P. (2000) Biochemistry 39, 8180-8186.