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Volumn 17, Issue 1, 2011, Pages 29-33

Cytokine inhibition in severe asthma: Current knowledge and future directions

Author keywords

asthma; cytokine; monoclonal antibodies; receptor antagonists

Indexed keywords

AMG 317; BENRALIZUMAB; CYTOKINE RECEPTOR ANTAGONIST; GOLIMUMAB; INFLIXIMAB; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 5 ANTIBODY; INTERLEUKIN 9; LEBRIKIZUMAB; MEDI 528; MEPOLIZUMAB; PITRAKINRA; PLACEBO; TRALOKINUMAB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 78650515905     PISSN: 10705287     EISSN: 15316971     Source Type: Journal    
DOI: 10.1097/MCP.0b013e3283413105     Document Type: Article
Times cited : (37)

References (13)
  • 1
    • 0034995872 scopus 로고    scopus 로고
    • Efficacy of soluble IL-4 receptor for the treatment of adults with asthma
    • Borish LC, Nelson HS, Corren J, et al. Efficacy of soluble IL-4 receptor for the treatment of adults with asthma. J Allergy Clin Immunol 2001; 107:963-970.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 963-970
    • Borish, L.C.1    Nelson, H.S.2    Corren, J.3
  • 2
    • 0036379740 scopus 로고    scopus 로고
    • Preclinical efficacy and safety of pascolizumab (SB 240683): A humanized antiinterleukin-4 antibody with therapeutic potential in asthma
    • Hart TK, Blackburn MN, Brigham-Burke M, et al. Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized antiinterleukin-4 antibody with therapeutic potential in asthma. Clin Exp Immunol 2002; 130:93-100.
    • (2002) Clin Exp Immunol , vol.130 , pp. 93-100
    • Hart, T.K.1    Blackburn, M.N.2    Brigham-Burke, M.3
  • 3
    • 32644490529 scopus 로고    scopus 로고
    • Evidence of a role of tumor necrosis factor alpha in refractory asthma
    • Berry MA, Hargadon B, Shelley M, et al. Evidence of a role of tumor necrosis factor alpha in refractory asthma. N Engl J Med 2006; 354:697-708.
    • (2006) N Engl J Med , vol.354 , pp. 697-708
    • Berry, M.A.1    Hargadon, B.2    Shelley, M.3
  • 4
    • 33749438560 scopus 로고    scopus 로고
    • The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma
    • Erin EM, Leaker BR, Nicholson GC, etal. The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma. Am J Respir Crit Care Med 2006; 174:753-762.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 753-762
    • Erin, E.M.1    Leaker, B.R.2    Nicholson, G.C.3
  • 5
    • 62549084077 scopus 로고    scopus 로고
    • A randomized, double-blind placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma
    • Wenzel SE, Barnes P, Bleecker ER, et al. A randomized, double-blind placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med 2009; 179:549-558.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 549-558
    • Wenzel, S.E.1    Barnes, P.2    Bleecker, E.R.3
  • 6
    • 36749065556 scopus 로고    scopus 로고
    • A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma
    • Flood-Page P, Swenson C, Faiferman I, et al. A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma. Am J Respir Crit Care Med 2007; 176:1062-1071.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1062-1071
    • Flood-Page, P.1    Swenson, C.2    Faiferman, I.3
  • 7
    • 61849086181 scopus 로고    scopus 로고
    • Mepolizumab and exacerbations of refractory eosinophilic asthma
    • Haldar P, Brightling CE, Hargadon B, etal. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009; 360:973-984.
    • (2009) N Engl J Med , vol.360 , pp. 973-984
    • Haldar, P.1    Brightling, C.E.2    Hargadon, B.3
  • 8
    • 61849155730 scopus 로고    scopus 로고
    • Mepolizumab for prednisone-depen-dent asthma with sputum eosinophilia
    • Nair P, Pizzichini MM, Kjarsgaard M, etal. Mepolizumab for prednisone-depen-dent asthma with sputum eosinophilia. N Engl J Med 2009; 360:985-993.
    • (2009) N Engl J Med , vol.360 , pp. 985-993
    • Nair, P.1    Pizzichini, M.M.2    Kjarsgaard, M.3
  • 9
    • 35348909044 scopus 로고    scopus 로고
    • Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: Results of two phase 2a studies
    • Wenzel S, Wilbraham D, Fuller R, etal. Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet 2007; 370:1422-1431.
    • (2007) Lancet , vol.370 , pp. 1422-1431
    • Wenzel, S.1    Wilbraham, D.2    Fuller, R.3
  • 10
    • 77953039047 scopus 로고    scopus 로고
    • A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma
    • Corren J, Busse W, Meltzer EO, etal. A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am J Respir Crit Care Med 2010; 181:788-796.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 788-796
    • Corren, J.1    Busse, W.2    Meltzer, E.O.3
  • 11
    • 77950801090 scopus 로고    scopus 로고
    • MEDI-528, an anti-IL-9 humanized antibody for the treatment of asthma
    • Antoniu SA. MEDI-528, an anti-IL-9 humanized antibody for the treatment of asthma. Curr Opin Mol Ther 2010; 12:233-239.
    • (2010) Curr Opin Mol Ther , vol.12 , pp. 233-239
    • Antoniu, S.A.1
  • 12
    • 75749149721 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin
    • He R, Geha RS. Thymic stromal lymphopoietin. Ann N Y Acad Sci 2010; 1183:13-24.
    • (2010) Ann N y Acad Sci , vol.1183 , pp. 13-24
    • He, R.1    Geha, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.