5-Aza-2′-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins

FASEB Journal

Volumn 26, Issue 1, 2012, Pages 449-459

  Zheng, Zhixing ^a   Li, Lian ^a   Liu, Xiangyu ^a   Wang, Donglai ^a   Tu, Bo ^a   Wang, Lina ^a   Wang, Haiying ^a   Zhu, Wei Guo ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Histone modification; MDM2

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2D; HISTONE; PROTEASOME; PROTEIN MDM2; PROTEIN P107; PROTEIN P130; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A;

ARTICLE; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; RNA INTERFERENCE;

ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; CELL LINE, TUMOR; COLONIC NEOPLASMS; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HISTONES; HUMANS; LUNG NEOPLASMS; OSTEOSARCOMA; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-MDM2; RETINOBLASTOMA PROTEIN; RETINOBLASTOMA-LIKE PROTEIN P107; RETINOBLASTOMA-LIKE PROTEIN P130;

EID: 84855404223     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-190025     Document Type: Article

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