5-Aza-2′-deoxycytidine Activates the p53/p21Waf1/Cip1 Pathway to Inhibit Cell Proliferation

Journal of Biological Chemistry

Volumn 279, Issue 15, 2004, Pages 15161-15166

  Zhu, Wei Guo ^a   Hileman, Theresa ^b   Ke, Yang ^a   Wang, Peichang ^a   Lu, Shaoli ^a   Duan, Wenrui ^b   Dai, Zunyan ^c   Tong, Tanjun ^a   Villalona Calero, Miguel A ^b   Plass, Christoph ^c   Otterson, Gregory A ^b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b OHIO STATE UNIVERSITY   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCENTRATION (PROCESS); DATA REDUCTION; DNA; GENES; VIRUSES;

ANTINEOPLASTIC ACTIVITY; BINDING SITES; CELL CYCLE; CELL DEATH;

BIOCHEMISTRY;

5 AZA 2' DEOXYCYTIDINE; PROTEIN P21; PROTEIN P53;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; COVALENT BOND; DEMETHYLATION; DNA METHYLATION; DRUG MECHANISM; GENE DELETION; HUMAN; HUMAN CELL; NONHUMAN; PAPILLOMA VIRUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; WILD TYPE;

ANTIOXIDANTS; AZACITIDINE; BINDING SITES; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; COMET ASSAY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA DAMAGE; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; LUCIFERASES; MODELS, GENETIC; MUTAGENESIS, SITE-DIRECTED; ONCOGENE PROTEINS, VIRAL; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; SULFITES; TIME FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; PAPILLOMAVIRUS;

EID: 2442622595     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M311703200     Document Type: Article

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