Interleukin-33 suppresses Notch ligand expression and prevents goblet cell depletion in dextran sulfate sodium-induced colitis

International Journal of Molecular Medicine

Volumn 28, Issue 4, 2011, Pages 573-578

  Imaeda, Hirotsugu ^a   Andoh, Akira ^a   Aomatsu, Tomoki ^a   Uchiyama, Kazuhiko ^b   Bamba, Shigeki ^a   Tsujikawa, Tomoyuki ^a   Naito, Yuji ^b   Fujiyama, Yoshihide ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Delta like 1; Goblet cell; Interleukin 33; Jagged1

Indexed keywords

DEXTRAN SULFATE; INTERLEUKIN 33; JAGGED1; MESSENGER RNA; NOTCH RECEPTOR; PROTEIN DELTA LIKE 1; PROTEIN DELTA LIKE 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL HYPERPLASIA; COLITIS; CONTROLLED STUDY; DISEASE EXACERBATION; GOBLET CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; T CELL DEPLETION;

ANIMALS; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; COLITIS; COLON; DEXTRAN SULFATE; GOBLET CELLS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 79960752111     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.718     Document Type: Article

References (23)

1. Schmitz J, Owyang A, Oldham E, et al: IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23: 479-490, 2005.
2. Arend WP, Palmer G and Gabay C: IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 223: 20-38, 2008.
3. Sanada S, Hakuno D, Higgins LJ, Schreiter ER, McKenzie AN and Lee RT: IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system. J Clin Invest 117: 1538-1549, 2007.
4. Nishida A, Andoh A, Imaeda H, et al: Expression of interleukin-1-like cytokine interleukin-33 and its receptor complex (ST2L and IL-1RAcP) in human pancreatic myofibroblasts. Gut 59: 531-541, 2009.
5. Marvie P, Lisbonne M, L'Helgoualc'h A, et al: Interleukin-33 overexpression is associated with liver fibrosis in mice and humans. J Cell Mol Med 14: 1726-1739, 2009.
6. Kondo Y, Yoshimoto T, Yasuda K, et al: Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int Immunol 20: 791-800, 2008.
7. Zhiguang X, Wei C, Steven R, et al: Over-expression of IL-33 leads to spontaneous pulmonary inflammation in mIL-33 transgenic mice. Immunol Lett 131: 159-165, 2010.
8. Shinoda M, Shin-Ya M, Naito Y, et al: Early-stage blocking of Notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-induced colitis in mice. J Gastroenterol 45: 608-617, 2010.
9. Kinoshita K, Taupin DR, Itoh H and Podolsky DK: Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor. Mol Cell Biol 20: 4680-4690, 2000.
10. Katoh M: Notch signaling in gastrointestinal tract (Review). Int J Oncol 30: 247-251, 2007.
11. Nakamura T, Tsuchiya K and Watanabe M: Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision. J Gastroenterol 42: 705-710, 2007.
12. Murayama M, Okamoto R, Tsuchiya K, et al: Musashi-1 suppresses expression of Paneth cell-specific genes in human intestinal epithelial cells. J Gastroenterol 44: 173-182, 2009.
13. Iwasaki M, Tsuchiya K, Okamoto R, et al: Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hath1 and Klf4. J Gastroenterol 46: 191-202, 2011.
14. Yang Q, Bermingham NA, Finegold MJ and Zoghbi HY: Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294: 2155-2158, 2001.
15. Jensen J, Pedersen EE, Galante P, et al: Control of endodermal endocrine development by Hes-1. Nat Genet 24: 36-44, 2000.
16. Okamoto R, Tsuchiya K, Nemoto Y, et al: Requirement of Notch activation during regeneration of the intestinal epithelia. Am J Physiol Gastrointest Liver Physiol 296: G23-G35, 2009.
17. van Es JH, van Gijn ME, Riccio O, et al: Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435: 959-963, 2005.
18. Mahida YR, Beltinger J, Makh S, et al: Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2. Am J Physiol 273: G1341-G1348, 1997.
19. Andoh A, Fujino S, Bamba S, et al: IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts. J Immunol 169: 1683-1687, 2002.
20. Uchiyama K, Naito Y, Takagi T, et al: Carbon monoxide enhance colonic epithelial restitution via FGF15 derived from colonic myofibroblasts. Biochem Biophys Res Commun 391: 1122-1126, 2010.
21. Cooper HS, Murthy SN, Shah RS and Sedergran DJ: Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69: 238-249, 1993.
22. Rath HC, Herfarth HH, Ikeda JS, et al: Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. J Clin Invest 98: 945-953, 1996.
23. Mayer L: Evolving paradigms in the pathogenesis of IBD. J Gastroenterol 45: 9-16, 2010.