Growth factors and anticatabolic substances for prevention and management of intervertebral disc degeneration

Stem Cells International

Volumn , Issue , 2012, Pages

  Longo, Umile Giuseppe ^a,b   Petrillo, Stefano ^a,b   Franceschetti, Edoardo ^a,b   Maffulli, Nicola ^c   Denaro, Vincenzo ^a,b  

^a UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANTIINFLAMMATORY AGENT; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CPA 926; ETANERCEPT; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBRONECTIN; GROWTH DIFFERENTIATION FACTOR 5; GROWTH FACTOR; INFLIXIMAB; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; NITRIC OXIDE; OSTEOGENIC PROTEIN 1; PLACEBO; PROSTAGLANDIN E2; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT OSTEOGENIC PROTEIN 1; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG;

ALLOGRAFT; ARTHRODESIS; BIOLOGICAL THERAPY; CARTILAGE CELL; CHEMONUCLEOLYSIS; CONSERVATIVE TREATMENT; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; HUMAN; INTERVERTEBRAL DISK DEGENERATION; INTERVERTEBRAL DISKECTOMY; ISCHIALGIA; LOW DRUG DOSE; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SINGLE DRUG DOSE; THROMBOCYTE RICH PLASMA; UNSPECIFIED SIDE EFFECT; VIRAL GENE THERAPY;

EID: 84855272638     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2012/897183     Document Type: Review

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109. Khan W. S., Longo U. G., ACI and MACI procedures for cartilage repair utilise mesenchymal stem cells rather than chondrocytes Medical Hypotheses 2011 77 2 309
110. Khanna A., Gougoulias N., Longo U. G., Maffulli N., Minimally invasive total knee arthroplasty: a systematic review Orthopedic Clinics of North America 2009 40 4 479 489
111. Khanna A., Friel M., Gougoulias N., Longo U. G., Maffulli N., Prevention of adhesions in surgery of the flexor tendons of the hand: what is the evidence? British Medical Bulletin 2009 90 1 85 109
112. Knobloch K., Schreibmueller L., Longo U. G., Vogt P. M., Eccentric exercises for the management of tendinopathy of the main body of the Achilles tendon with or without an AirHeel Brace. A randomized controlled trial. B: effects of compliance Disability and Rehabilitation 2008 30 2022 1692 1696
113. Knobloch K., Schreibmueller L., Longo U. G., Vogt P. M., Eccentric exercises for the management of tendinopathy of the main body of the Achilles tendon with or without the AirHeel Brace. A randomized controlled trial. A: effects on pain and microcirculation Disability and Rehabilitation 2008 30 2022 1685 1691
114. Lippi G., Longo U. G., Maffulli N., Genetics and sports British Medical Bulletin 2010 93 1 27 47
115. Ames P. R.J., Longo U. G., Denaro V., Maffulli N., Achilles tendon problems: not just an orthopaedic issue Disability and Rehabilitation 2008 30 20-22 1646 1650
116. Becher C., Driessen A., Hess T., Longo U. G., Maffulli N., Thermann H., Microfracture for chondral defects of the talus: maintenance of early results at midterm follow-up Knee Surgery, Sports Traumatology, Arthroscopy 2010 18 5 656 663
117. Capuano L., Hardy P., Longo U. G., Denaro V., Maffulli N., No difference in clinical results between femoral transfixation and bio-interference screw fixation in hamstring tendon ACL reconstruction. A preliminary study Knee 2008 15 3 174 179
118. Capuano L., Poulain S., Hardy P., Longo U. G., Denaro V., Maffulli N., No correlation between physicians administered elbow rating systems and patient's satisfaction Journal of Sports Medicine and Physical Fitness 2011 51 255 259
119. Franceschi F., Longo U. G., Ruzzini L., Rizzello G., Denaro V., Arthroscopic management of calcific tendinitis of the subscapularis tendon Knee Surgery, Sports Traumatology, Arthroscopy 2007 15 12 1482 1485
120. Franceschi F., Longo U. G., Ruzzini L., Simoni P., Zobel B. B., Denaro V., Bilateral complete discoid medial meniscus combined with posterior cyst formation Knee Surgery, Sports Traumatology, Arthroscopy 2007 15 3 266 268
121. Franceschi F., Longo U. G., Ruzzini L., Leonardi F., Rojas M., Gualdi G., Denaro V., Dislocation of an enlarged fabella as uncommon cause of knee pain. A case report Knee 2007 14 4 330 332 (Pubitemid 47044969)
122. Franceschi F., Ruzzini L., Longo U. G., Martina F. M., Beomonte Zobel B., Maffulli N., Denaro V., Equivalent clinical results of arthroscopic single-row and double-row suture anchor repair for rotator cuff tears: a randomized controlled trial American Journal of Sports Medicine 2007 35 8 1254 1260 (Pubitemid 47084206)
123. Franceschi F., Longo U. G., Ruzzini L., Denaro V., Isolated tuberculosis of the patellar tendon The Journal of Bone and Joint Surgery. British 2007 89 11 1525 1526 (Pubitemid 350273253)
124. Franceschi F., Longo G. U., Ruzzini L., Rizzello G., Maffulli N., Denaro V., The Roman Bridge: a double pulley-suture bridges technique for rotator cuff repair BMC Musculoskeletal Disorders 2007 8, article 123
125. Franceschi F., Longo U. G., Ruzzini L., Papalia R., Rizzello G., Denaro V., To detach the long head of the biceps tendon after tenodesis or not: outcome analysis at the 4-year follow-up of two different techniques International Orthopaedics 2007 31 4 537 545 (Pubitemid 47101361)
126. Franceschi F., Longo U. G., Ruzzini L., Rizzello G., Maffulli N., Denaro V., Arthroscopic salvage of failed arthroscopic Bankart repair: a prospective study with a minimum follow-up of 4 years American Journal of Sports Medicine 2008 36 7 1330 1336 (Pubitemid 352000004)
127. Franceschi F., Giuseppe Longo U., Ruzzini L., Rizzello G., Maffulli N., Denaro V., No advantages in repairing a type II superior labrum anterior and posterior (SLAP) lesion when associated with rotator cuff repair in patients over age 50: a randomized controlled trial American Journal of Sports Medicine 2008 36 2 247 253
128. Franceschi F., Longo U. G., Ruzzini L., Papalia R., Maffulli N., Denaro V., Quadriceps tendon-patellar bone autograft for anterior cruciate ligament reconstruction: a technical note Bulletin of the NYU Hospital for Joint Diseases 2008 66 2 120 123 (Pubitemid 351898377)
129. Franceschi F., Longo U. G., Ruzzini L., Marinozzi A., Maffulli N., Denaro V., Simultaneous arthroscopic implantation of autologous chondrocytes and high tibial osteotomy for tibial chondral defects in the varus knee Knee 2008 15 4 309 313
130. Franceschi F., Longo U. G., Ruzzini L., Rizzello G., Maffulli N., Denaro V., Soft tissue tenodesis of the long head of the biceps tendon associated to the Roman Bridge repair BMC Musculoskeletal Disorders 2008 9, article 78
131. Longo U. G., Franceschi F., Ruzzini L., Rabitti C., Morini S., Maffulli N., Forriol F., Denaro V., Light microscopic histology of supraspinatus tendon ruptures Knee Surgery, Sports Traumatology, Arthroscopy 2007 15 11 1390 1394
132. Longo U. G., King J. B., Denaro V., Maffulli N., Double-bundle arthroscopic reconstruction of the anterior cruciate ligament: does the evidence add up? The Journal of Bone and Joint Surgery. British 2008 90 8 995 999
133. Longo U. G., Franceschi F., Ruzzini L., Rabitti C., Morini S., Maffulli N., Denaro V., Histopathology of the supraspinatus tendon in rotator cuff tears American Journal of Sports Medicine 2008 36 3 533 538 (Pubitemid 351253387)
134. Longo U. G., Ramamurthy C., Denaro V., Maffulli N., Minimally invasive stripping for chronic Achilles tendinopathy Disability and Rehabilitation 2008 30 20-22 1709 1713
135. Longo U. G., Franceschi F., Loppini M., Maffulli N., Denaro V., Rating systems for evaluation of the elbow British Medical Bulletin 2008 87 1 131 161
136. Longo U. G., Garau G., Denaro V., Maffulli N., Surgical management of tendinopathy of biceps femoris tendon in athletes Disability and Rehabilitation 2008 30 20-22 1602 1607
137. Longo U. G., Ronga M., Maffulli N., Achilles tendinopathy Sports Medicine and Arthroscopy Review 2009 17 2 112 126
138. Longo U. G., Ronga M., Maffulli N., Acute ruptures of the achilles tendon Sports Medicine and Arthroscopy Review 2009 17 2 127 138
139. Longo U. G., Franceschi F., Ruzzini L., Rabitti C., Morini S., Maffulli N., Denaro V., Characteristics at haematoxylin and eosin staining of ruptures of the long head of the biceps tendon British Journal of Sports Medicine 2009 43 8 603 607
140. Longo U. G., Franceschi F., Ruzzini L., Rabitti C., Nicola M., Denaro V., Foreign-body giant-cell reaction at the donor site after autologous
141. Longo U. G., Franceschi F., Ruzzini L., Spiezia F., Maffulli N., Denaro V., Higher fasting plasma glucose levels within the normoglycaemic range and rotator cuff tears British Journal of Sports Medicine 2009 43 4 284 287
142. Longo U. G., Maffulli N., Denaro V., Minimally invasive total knee arthroplasty The New England Journal of Medicine 2009 361 6 633 634
143. Longo U. G., Rittweger J., Garau G., Radonic B., Gutwasser C., Gilliver S. F., Kusy K., Zieliski J., Felsenberg D., Maffulli N., No influence of age, gender, weight, height, and impact profile in achilles tendinopathy in masters track and field athletes American Journal of Sports Medicine 2009 37 7 1400 1405
144. Longo U. G., Maffulli N., Denaro V., Rivaroxaban versus enoxaparin after total knee arthroplasty The Lancet 2009 374 9691 681 682
145. Longo U. G., Fazio V., Poeta M. L., Rabitti C., Franceschi F., Maffulli N., Denaro V., Bilateral consecutive rupture of the quadriceps tendon in a man with BstUI polymorphism of the COL5A1 gene Knee Surgery, Sports Traumatology, Arthroscopy 2010 18 4 514 518
146. Longo U. G., Forriol F., Maffulli N., Denaro V., Evaluation of histological scoring systems for tissue-engineered, repaired and osteoarthritic cartilage Osteoarthritis and Cartilage 2010 18 7 1001
147. Longo U. G., Franceschetti E., Maffulli N., Denaro V., Hip arthroscopy: state of the art British Medical Bulletin 2010 96 1 131 157
148. Longo U. G., Loppini M., Denaro L., Maffulli N., Denaro V., Rating scales for low back pain British Medical Bulletin 2010 94 1 81 144
149. Longo U. G., Franceschi F., Spiezia F., Forriol F., Maffulli N., Denaro V., Triglycerides and total serum cholesterol in rotator cuff tears: do they matter? British Journal of Sports Medicine 2010 44 13 948 951
150. Longo U. G., Denaro L., Campi S., Maffulli N., Denaro V., Upper cervical spine injuries: indications and limits of the conservative management in Halo vest. A systematic review of efficacy and safety Injury 2010 41 11 1127 1135
151. Longo U. G., Forriol F., Campi S., Maffulli N., Denaro V., Animal models for translational research on shoulder pathologies: from bench to bedside Sports Medicine and Arthroscopy Review 2011 19 3 184 193
152. Longo U. G., Buchmann S., Berton A., Maffulli N., Denaro V., Arthroscopic knots and strength sutures for rotator cuff repair Sports Medicine and Arthroscopy Review 2011 19 3 251 265
153. Longo U. G., Fazio V. M., Poeta M. L., Rabitti C., Franceschi F., Maffulli N., Denaro V., Bilateral consecutive rupture of the quadriceps tendon in a man with BstUI polymorphism of the COL5A1 gene Knee Surgery, Sports Traumatology, Arthroscopy 2011 19 8 1404 1405
154. Longo U. G., Berton A., Ahrens P. M., Maffulli N., Denaro V., Clinical tests for the diagnosis of rotator cuff disease Sports Medicine and Arthroscopy Review 2011 19 3 266 278
155. Longo U. G., Banerjee S., Barber J., Chambler A., Cobiella C., Corbett S., Crowther M., Drew S., Francis A., Lee M., Garlick N., Packham I., Pearse Y., Richards A., Roberts C., Tennent D., Tims E., Ahrens P. M., Conservative management versus open reduction and internal fixation for mid-shaft clavicle fractures in adultsthe Clavicle Trial: study protocol for a multicentre randomized controlled trial Trials 2011 12, article 57
156. Longo U. G., Berton A., Khan W. S., Maffulli N., Denaro V., Histopathology of rotator cuff tears Sports Medicine and Arthroscopy Review 2011 19 3 227 236
157. Longo U. G., Rittweger J., Garau G., Radonic B., Gutwasser C., Gilliver S. F., Kusy K., Zieliski J., Felsenberg D., Maffulli N., Patellar tendinopathy in master track and field athletes: influence of impact profile, weight, height, age and gender Knee Surgery, Sports Traumatology, Arthroscopy 2011 19 3 508 512
158. Longo U. G., Vasta S., Maffulli N., Denaro V., Scoring systems for the functional assessment of patients with rotator cuff pathology Sports Medicine and Arthroscopy Review 2011 19 3 310 320
159. Longo U. G., Franceschi F., Spiezia F., Marinozzi A., Maffulli N., Denaro V., The low-profile Roman bridge technique for knotless double-row repair of the rotator cuff Archives of Orthopaedic and Trauma Surgery 2011 131 3 357 361
160. Longo U. G., Lamberti A., Rizzello G., Maffulli N., Denaro V., Synthetic augmentation in massive rotator cuff tears Medicine and Sport Science 2012 57 168 177
161. Longo U. G., Marinozzi A., Cazzato L., Rabitti C., Maffulli N., Denaro V., Tuberculosis of the shoulder Journal of Shoulder and Elbow Surgery 2011 20 4 e19 e21
162. Longo U. G., Huijsmans P. E., Maffulli N., Denaro V., De Beer J. F., Video analysis of the mechanisms of shoulder dislocation in four elite rugby players Journal of Orthopaedic Science 2011 16 389 397
163. Maffulli N., Ajis A., Longo U. G., Denaro V., Chronic rupture of tendo Achillis Foot and Ankle Clinics 2007 12 4 583 596
164. Maffulli N., Longo U. G., Conservative management for tendinopathy: is there enough scientific evidence? Rheumatology 2008 47 4 390 391
165. Maffulli N., Walley G., Sayana M., Longo U. G., Denaro V., Eccentric calf muscle training in athletic patients with Achilles tendinopathy Disability and Rehabilitation 2008 30 20-22 1677 1684
166. Maffulli N., Longo U. G., How do eccentric exercises work in tendinopathy? Rheumatology 2008 47 10 1444 1445
167. Maffulli N., Longo U. G., Gougoulias N., Denaro V., Ipsilateral free semitendinosus tendon graft transfer for reconstruction of chronic tears of the Achilles tendon BMC Musculoskeletal Disorders 2008 9, article 100
168. Maffulli N., Longo U. G., Testa V., Oliva F., Capasso G., Denaro V., Italian translation of the VISA-A score for tendinopathy of the main body of the Achilles tendon Disability and Rehabilitation 2008 30 20-22 1635 1639
169. Maffulli N., Longo U. G., Franceschi F., Rabitti C., Denaro V., Movin and bonar scores assess the same characteristics of tendon histology Clinical Orthopaedics and Related Research 2008 466 7 1605 1611
170. Maffulli N., Testa V., Capasso G., Oliva F., Panni A. S., Longo U. G., King J. B., Surgery for chronic Achilles tendinopathy produces worse results in women Disability and Rehabilitation 2008 30 20-22 1714 1720
171. Maffulli N., Longo U. G., Testa V., Oliva F., Capasso G., Denaro V., VISA-P score for patellar tendinopathy in males: adaptation to Italian Disability and Rehabilitation 2008 30 20-22 1621 1624
172. Maffulli N., Longo U. G., Denaro V., Anterior cruciate ligament tear The New England Journal of Medicine 2009 360 14 1463
173. Maffulli N., Longo U. G., Oliva F., Denaro V., Coppola C., Bosch osteotomy and scarf osteotomy for hallux valgus correction Orthopedic Clinics of North America 2009 40 4 515 524
174. Maffulli N., Longo U. G., Oliva F., Ronga M., Denaro V., Minimally invasive surgery of the achilles tendon Orthopedic Clinics of North America 2009 40 4 491 498
175. Maffulli N., Longo U. G., Loppini M., Denaro V., Current treatment options for tendinopathy Expert Opinion on Pharmacotherapy 2010 11 13 2177 2186
176. Maffulli N., Longo U. G., Ronga M., Khanna A., Denaro V., Favorable outcome of percutaneous repair of achilles tendon ruptures in the elderly Clinical Orthopaedics and Related Research 2010 468 4 1039 1046
177. Maffulli N., Longo U. G., Spiezia F., Denaro V., Free hamstrings tendon transfer and interference screw fixation for less invasive reconstruction of chronic avulsions of the Achilles tendon Knee Surgery, Sports Traumatology, Arthroscopy 2010 18 2 269 273
178. Maffulli N., Spiezia F., Longo U. G., Denaro V., Less-invasive reconstruction of chronic achilles tendon ruptures using a peroneus brevis tendon transfer American Journal of Sports Medicine 2010 38 11 2304 2312
179. Maffulli N., Longo U. G., Gougoulias N., Loppini M., Denaro V., Long-term health outcomes of youth sports injuries British Journal of Sports Medicine 2010 44 1 21 25
180. Maffulli N., Longo U. G., Denaro V., Novel approaches for the management of tendinopathy The Journal of Bone and Joint Surgery. American 2010 92 15 2604 2613
181. Maffulli N., Longo U. G., Spiezia F., Denaro V., Sports injuries in young athletes: long-term outcome and prevention strategies Physician and Sportsmedicine 2010 38 2 29 34
182. Maffulli N., Longo U. G., Maffulli G. D., Khanna A., Denaro V., Achilles tendon ruptures in diabetic patients Archives of Orthopaedic and Trauma Surgery 2011 131 1 33 38
183. Maffulli N., Longo U. G., Maffulli G. D., Khanna A., Denaro V., Achilles tendon ruptures in elite athletes Foot and Ankle International 2011 32 1 9 15
184. Maffulli N., Longo U. G., Spiezia F., Denaro V., Aetiology and prevention of injuries in elite young athletes Medicine and Sport Science 2010 56 187 200
185. Maffulli N., Longo U. G., Berton A., Loppini M., Denaro V., Biological factors in the pathogenesis of rotator cuff tears Sports Medicine and Arthroscopy Review 2011 19 3 194 201
186. Maffulli N., Longo U. G., Marinozzi A., Denaro V., Hallux valgus: effectiveness and safety of minimally invasive surgery. A systematic review British Medical Bulletin 2011 97 1 149 167
187. Maffulli N., Longo U. G., Maffulli G. D., Rabitti C., Khanna A., Denaro V., Marked pathological changes proximal and distal to the site of rupture in acute Achilles tendon ruptures Knee Surgery, Sports Traumatology, Arthroscopy 2011 19 4 680 687
188. Maffulli N., Longo U. G., Gougoulias N., Caine D., Denaro V., Sport injuries: a review of outcomes British Medical Bulletin 2011 97 1 47 80