Effectiveness of a mucolythic agent as a local adjuvant in revision lumbar spine surgery

European Spine Journal

Volumn 17, Issue 12, 2008, Pages 1752-1756

  Denaro, Vincenzo ^a   Di Martino, Alberto ^a   Longo, Umile Giuseppe ^a   Costa, Vincenzo ^a   Papalia, Rocco ^a   Forriol, Francisco ^b   Denaro, Luca ^c  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^b Research Unit FREMAP Hospital   (Spain)

^c CATHOLIC UNIVERSITY   (Italy)

Author keywords

Chemical dissection; Epidural fibrosis; Lumbar spine; MESNA; Revision surgery

Indexed keywords

HEMOGLOBIN; MESNA; MUCOLYTIC AGENT; SODIUM CHLORIDE; UNCLASSIFIED DRUG; UROMIXETAN;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DISSECTION; DRUG EFFICACY; DURA MATER; DURA MATER TEAR; EPIDURAL FIBROSIS; EPIFASCIAL INFECTION; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; INCIDENCE; INTERVERTEBRAL DISK DEGENERATION; LENGTH OF STAY; LUMBAR SPINE; MALE; OPERATION DURATION; OUTCOME ASSESSMENT; PERIOPERATIVE COMPLICATION; PEROPERATIVE CARE; POSTOPERATIVE CARE; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE PAIN; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; REVISION LUMBAR SPINE SURGERY; SCAR FORMATION; SPINE DISEASE; SPINE SURGERY; SURGICAL TECHNIQUE; TREATMENT OUTCOME; VERTEBRAL CANAL;

ADULT; CICATRIX; DISSECTION; DURA MATER; EPIDURAL SPACE; EXPECTORANTS; FAILED BACK SURGERY SYNDROME; FEMALE; FIBROSIS; HUMANS; LUMBAR VERTEBRAE; MALE; MESNA; MIDDLE AGED; NEUROSURGICAL PROCEDURES; OUTCOME ASSESSMENT (HEALTH CARE); POSTOPERATIVE HEMORRHAGE; PROSPECTIVE STUDIES; PROTECTIVE AGENTS; REOPERATION; SPINAL CANAL; TIME FACTORS; TREATMENT OUTCOME;

EID: 57049137671     PISSN: 09406719     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00586-008-0802-y     Document Type: Article

References (26)

1. RN Alkalay DH Kim DW Urry J Xu TM Parker PA Glazer 2003 Prevention of postlaminectomy epidural fibrosis using bioelastic materials Spine 1 28 1659 1665 10.1097/00007632-200308010-00006
2. SJ Atlas RB Keller YA Wu RA Deyo DE Singer 2005 Long-term outcomes of surgical and nonsurgical management of sciatica secondary to a lumbar disc herniation: 10 year results from the maine lumbar spine study Spine 30 8 927 935
3. SJ Atlas RB Keller YA Wu RA Deyo DE Singer 2005 Long-term outcomes of surgical and nonsurgical management of lumbar spinal stenosis: 8 to 10 year results from the maine lumbar spine study Spine 30 8 936 943
4. L Benassi G Benassi CT Kaihura L Marconi L Ricci E Vadora 2003 Chemically assisted dissection of tissues in laparoscopic excision of endometriotic cysts J Am Assoc Gynecol Laparosc 10 2 205 209 10.1016/S1074-3804(05)60300-3
5. L Benassi G Lopopolo F Pazzoni L Ricci C Kaihura F Piazza 2000 Chemically assisted dissection of tissues: an interesting support in abdominal myomectomy J Am Coll Surg 191 1 65 69 10.1016/S1072-7515(00)00296-9
6. C Cabukoglu O Guven Y Yildirim H Kara SS Ramadan 2004 Effect of sagittal plane deformity of the lumbar spine on epidural fibrosis formation after laminectomy: an experimental study in the rat Spine 29 20 2242 2247
7. V Denaro F Forriol A Di Martino L Denaro R Papalia G Caione 2001 Effect of a mucolytic agent on collagen fibres: an optical and polarized light histological study Eur J Orthop Surg Traumatol 11 209 212 10.1007/BF01686890
8. EW Fritsch J Heisel S Rupp 1996 The failed back surgery syndrome: reasons, intraoperative findings, and long-term results: a report of 182 operative treatments Spine 21 5 626 633 10.1097/00007632-199603010-00017
9. FH Geisler 1999 Prevention of peridural fibrosis: current methodologies Neurol Res 21 Suppl 1 S9 S22
10. R Henderson B Weir L Davis B Mielke M Grace 1993 Attempted experimental modification of the postlaminectomy membrane by local instillation of recombinant tissue-plasminogen activator gel Spine 18 10 1268 1272 10.1097/00007632-199308000-00004
11. LD Hieb DL Stevens 2001 Spontaneous postoperative cerebrospinal fluid leaks following application of anti-adhesion barrier gel: case report and review of the literature Spine 26 7 748 751
12. JN Katz SJ Lipson MG Larson JM McInnes AH Fossel MH Liang 1991 The outcome of decompressive laminectomy for degenerative lumbar stenosis J Bone Joint Surg Am 73 6 809 816
13. S Kemaloglu U Ozkan F Yilmaz K Nas A Gur H Acemoglu 2003 Prevention of spinal epidural fibrosis by recombinant tissue plasminogen activator in rats Spinal Cord 41 8 427 431 10.1038/sj.sc.3101466
14. T Kitano JE Zerwekh ML Edwards Y Usui M Allen 1991 Viscous carboxymethylcellulose in the prevention of epidural scar formation Spine 16 7 820 823 10.1097/00007632-199107000-00023
15. AX Le DE Rogers EG Dawson MA Kropf DA De Grange RB Delamarter 2001 Unrecognized durotomy after lumbar discectomy: a report of four cases associated with the use of ADCON-L Spine 26 1 115 117 10.1097/00007632-200101010-00020
16. AD Malter B McNeney JD Loeser RA Deyo 1998 5-year reoperation rates after different types of lumbar spine surgery Spine 23 7 814 820 10.1097/00007632- 199804010-00015
17. JB Massie B Huang S Malkmus TL Yaksh CW Kim SR Garfin 2004 A preclinical post laminectomy rat model mimics the human post laminectomy syndrome J Neurosci Methods 137 2 283 289 10.1016/j.jneumeth.2004.02.036
18. Y Mikawa H Hamagami J Shikata S Higashi T Yamamuro SH Hyon 1986 An experimental study on prevention of postlaminectomy scar formation by the use of new materials Spine 11 8 843 846 10.1097/00007632-198610000-00021
19. CV Morgan-Hough PW Jones SM Eisenstein 2003 Primary and revision lumbar discectomy. A 16-year review from one centre J Bone Joint Surg Br 85 6 871 874
20. H Osterman R Sund S Seitsalo I Keskimaki 2003 Risk of multiple reoperations after lumbar discectomy: a population-based study Spine 28 6 621 627 10.1097/00007632-200303150-00019
21. S Ozgen S Naderi MM Ozek MN Pamir 1999 Findings and outcome of revision lumbar disc surgery J Spinal Disord 12 4 287 292 10.1097/00002517-199908000- 00003
22. KE Rodgers JT Robertson T Espinoza W Oppelt S Cortese GS diZerega 2003 Reduction of epidural fibrosis in lumbar surgery with Oxiplex adhesion barriers of carboxymethylcellulose and polyethylene oxide Spine J 3 4 277 283 10.1016/S1529-9430(03)00035-4
23. G Stewart BL Sachs 1996 Patient outcomes after reoperation on the lumbar spine J Bone Joint Surg Am 78 5 706 711
24. V Vincenti M Mondain E Pasanisi F Piazza JL Puel S Bacciu 1999 Cochlear effects of mesna application into the middle ear Ann N Y Acad Sci 28 884 425 432 10.1111/j.1749-6632.1999.tb08659.x
25. JC Wang HH Bohlman KD Riew 1998 Dural tears secondary to operations on the lumbar spine. Management and results after a two-year-min imum follow-up of eighty-eight patients J Bone Joint Surg Am 12 1728 1732
26. F Zheng FP Cammisa Jr HS Sandhu FP Girardi SN Khan 2002 Factors predicting hospital stay, operative time, blood loss, and transfusion in patients undergoing revision posterior lumbar spine decompression, fusion, and segmental instrumentation Spine 27 8 818 824 10.1097/00007632-200204150-00008