How do eccentric exercises work in tendinopathy?

Rheumatology

Volumn 47, Issue 10, 2008, Pages 1444-1445

  Maffulli, N ^a   Longo, U G ^b  

^a UNIVERSITY HOSPITAL OF NORTH STAFFORDSHIRE   (United Kingdom)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CHONDROITIN SULFATE; GLUTAMIC ACID; PROSTAGLANDIN E2; SUBSTANCE P;

ACHILLES TENDINITIS; BIOMECHANICS; CLINICAL TRIAL; CONSERVATIVE TREATMENT; EARLY DIAGNOSIS; EDITORIAL; ELECTROSTIMULATION THERAPY; GENE EXPRESSION REGULATION; HUMAN; KINESIOTHERAPY; MECHANOTRANSDUCTION; MUSCULOSKELETAL PAIN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REHABILITATION CARE; REST; TENDINITIS; TENDON INJURY; TENDON SURGERY; TENSILE STRENGTH; THERAPY EFFECT;

ACHILLES TENDON; EXERCISE; HUMANS; TENDINOPATHY; WOUND HEALING;

EID: 52949149761     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ken337     Document Type: Editorial

References (28)

1. Ames PR, Longo UG, Denaro V, Maffulli N. Achilles tendon problems: Not just an orthopaedic issue. Disabil Rehabil 2008;6:1-5.
2. Maffulli N, Ajis A, Longo UG, Denaro V. Chronic rupture of tendo Achillis. Foot Ankle Clin 2007;12:583-96.
3. Longo UG, Ramamurthy C, Denaro V, Maffulli N. Minimally invasive stripping for chronic Achilles tendinopathy. Disabil Rehabil 2008;19:1-5.
4. Maffulli N, Longo UG. Conservative management for tendinopathy: Is there enough scientific evidence? Rheumatology 2008;47:390-1.
5. Maffulli N, Longo UG, Franceschi F, Rabitti C, Denaro V. Movin and Bonar scores assess the same characteristics of tendon histology. Clin Orthop Relat Res 2008;466:1605-11.
6. Longo UG, Franceschi F, Ruzzini I. et al. Characteristics at Haematoxylin and Eosin staining of ruptures of the long head of the biceps tendon. Br J Sports Med. Advance Access published December 10, 2007, doi: 10.1136/bjsm.2007.039016.
7. Longo UG, Franceschi F, Ruzzini I. et al. Histopathology of the supraspinatus tendon in rotator cuff tears. Am J Sports Med 2008;36:533-8.
8. Longo UG, Franceschi F, Ruzzini I. et al. Light microscopic histology of supraspinatus tendon ruptures. Knee Surg Sports Traumatol Arthrosc 2007;15:1390-4.
9. Andres BM, Murrell GA. Treatment of tandinopathy: What works, what does not, and what is on the horizon. Clin Orthop, Relat Res 2008;466:1539-54.
10. Hampson K, Forsyth NR, El Haj A, Maffulli N. Tendon tissue engineering. In: Ashammakhi N, Reis R, Chiellini F, eds. Topics in tissue engineering, Vol. 4. 2008;1-21.
11. Wang JH. Mechanobiology of tendon. J Biomech 2006;39:1563-82.
12. Wang QW, Chen ZL, Piao YJ. Mesenchymal stem cells differentiate into tenocytes by bone morphogenetic protein (BMP) 12 gene transfer. J Biosci Bioeng 2005;100:418-22.
13. Steadman JR, Forster RS, Sifferskiold JP. Rehabilitation of the knee. Clin Sports Med 1989;8:605-27.
14. Zeichen J, van Griensven M, Bosch U. The proliferative response of isolated human tendon fibroblasts to cyclic biaxial mechanical strain. Am J Sports Med 2000;28:888-92.
15. Maffulli N, Walley G, Sayana MK, Longo UG, Denaro V. Eccentric calf muscle training in athletic patients with Achilles tendinopathy. Disabil Rehabil. Advance access published 2008, doi: 10.1080/09638280701786427.
16. Sayana MK, Maffulli N. Eccentric calf muscle training in non-athletic patients with Achilles tendinopathy. J Sci Med Sport 2007;10:52-8.
17. Mafi N, Lorenizon R, Alfredson H. Superior shon-term results with eccentric calf muscle training compared to concentric training in a randomized prospective multicenter study on patients with chronic Achilles tendinosis. Knee Surg Sports Traumatol Arthrosc 2001;9:42-7.
18. Roos EM, Engstrom M, Lagerquist A, Soderberg B. Clinical improvement after 6 weeks of eccentric exercise in patients with mid-portion Achilles tendinopathy - a randomized trial with 1-year follow-up. Scand J Med Sci Sports 2004;14:286-95.
19. Alfredson H, Pietila T, Jonsson P, Lorentzon R. Heavy-load eccentric calf muscle training for the treatment of chronic Achilles tendinosis. Am J Sports Med 1998;26:360-6.
20. Stanish WD, Rubinovich RM, Curwin S. Eccentric exercise in chronic tendinitis. Clin Orthop Relat Res 1986;208:65-8.
21. Rompe JD, Nafe B, Furia JP, Maffulli N. Eccentric loading, shock-wave treatment, or a wait-and-see policy for tendinopathy of the main body of tendo Achillis: A randomized controlled trial. Am J Sports Med 2007;35:374-83.
22. Silbernagel KG, Thomee R, Thomee P, Karlsson J. Eccentric overload training for patients with chronic Achilles tendon pain - a randomised controlled study with reliability testing of the evaluation methods. Scand J Med Sci Sports 2001;11:197-206.
23. Rees JD, Lichtwark GA, Wolman RL, Wilson AM. The mechanism for efficacy of eccentric loading in Achilles tendon injury; an in vivo study in humans. Rheumatology 2008;47:1493-7.
24. Jozsa L, Balint J, Kannus P, Jarvinen M, Lehto M. Mechanoreceptors in human myotendinous junction. Muscle Nerve 1993;16:453-7.
25. Khan KM, Cook JL, Maffulli N, Kannus P. Where is the pain coming from in tendinopathy? It may be biochemical, not only structural, in origin. Br J Sports Med 2000;34:81-3.
26. Alfredson H, Thorsen K, Lorentzon R. In situ microdlalysis in tendon tissue: High levels of glutamate, but not prostaglandin E2 in chronic Achilles tendon pain. Knee Surg Sports Traumatol Arthrosc 1999;7:378-81.
27. Leadbetter WB. Cell-matrix response in tendon injury. Clin Sports Med 1992;11:533-78.
28. Kader D, Saxena A, Movin T, Maffulli N. Achilles tendinopathy: Some aspects of basic science and clinical management. Br J Sports Med 2002;36:239-49.